-
1
-
-
84892138934
-
The impact of plant flavonoids on mammalian biology: Implications for immunity, inflammation and cancer
-
J.B. Harborne Chapman & Hall London
-
E. Middleton, and C. Kandaswami The impact of plant flavonoids on mammalian biology: implications for immunity, inflammation and cancer J.B. Harborne The Flavonoids 1994 Chapman & Hall London 619 652
-
(1994)
The Flavonoids
, pp. 619-652
-
-
Middleton, E.1
Kandaswami, C.2
-
2
-
-
0029888128
-
Structure-antioxidant activity relationships of flavonoids and phenolic acids
-
C.A. Rice-Evans, N.J. Miller, and G. Paganga Structure-antioxidant activity relationships of flavonoids and phenolic acids Free Rad. Biol. Med. 20 1996 933 956
-
(1996)
Free Rad. Biol. Med.
, vol.20
, pp. 933-956
-
-
Rice-Evans, C.A.1
Miller, N.J.2
Paganga, G.3
-
3
-
-
0026701521
-
Fruit, vegetables and cancer prevention: A review of the epidemiological evidence
-
G. Block, S. Patterson, and A. Subar Fruit, vegetables and cancer prevention: a review of the epidemiological evidence Nutr. Cancer 18 1992 1 29
-
(1992)
Nutr. Cancer
, vol.18
, pp. 1-29
-
-
Block, G.1
Patterson, S.2
Subar, A.3
-
4
-
-
0030254151
-
The Leon Goldberg memorial lecture: Antioxidants and disease prevention
-
A.T. Diplock The Leon Goldberg memorial lecture: antioxidants and disease prevention Food Chem. Toxicol. 34 1996 1013 1023
-
(1996)
Food Chem. Toxicol.
, vol.34
, pp. 1013-1023
-
-
Diplock, A.T.1
-
5
-
-
0031656737
-
Functional food science and defense against reactive oxidative species
-
A.T. Diplock, J.-L. Charleux, G. Crozier-Will, F.J. Kok, C. Rice-Evans, M. Roberfroid, W. Stahl, and J. Vina-Ribes Functional food science and defense against reactive oxidative species Br. J. Nutr. 80 1998 S77
-
(1998)
Br. J. Nutr.
, vol.80
, pp. 77
-
-
Diplock, A.T.1
Charleux, J.-L.2
Crozier-Will, G.3
Kok, F.J.4
Rice-Evans, C.5
Roberfroid, M.6
Stahl, W.7
Vina-Ribes, J.8
-
6
-
-
0030346857
-
Micronutrients (vitamins and minerals) as cancer-preventive agents
-
G.S. Omenn Micronutrients (vitamins and minerals) as cancer-preventive agents IARC Sci. Publ. 139 1997 33 45
-
(1997)
IARC Sci. Publ.
, vol.139
, pp. 33-45
-
-
Omenn, G.S.1
-
7
-
-
0025885064
-
Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia
-
E.E. Deschner, J. Ruperto, G. Wong, and H.L. Newmark Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia Carcinogenesis 12 1991 1193 1196
-
(1991)
Carcinogenesis
, vol.12
, pp. 1193-1196
-
-
Deschner, E.E.1
Ruperto, J.2
Wong, G.3
Newmark, H.L.4
-
8
-
-
0025734510
-
Quercetin inhibits the growth of a multidrug resistant estrogen-receptor-negative MCF-7 human breast-cancer cell line expressing type II estrogen binding sites
-
G. Scambia, F.O. Ranelletti, P. Benedetti Panici, M. Piantelli, G. Bonanno, R. DeVincemo, G. Ferrandina, L. Piercelli, A. Capelli, and S. Mancuso Quercetin inhibits the growth of a multidrug resistant estrogen-receptor- negative MCF-7 human breast-cancer cell line expressing type II estrogen binding sites Cancer Chemother. Pharmacol. 28 1991 255 258
-
(1991)
Cancer Chemother. Pharmacol.
, vol.28
, pp. 255-258
-
-
Scambia, G.1
Ranelletti, F.O.2
Benedetti Panici, P.3
Piantelli, M.4
Bonanno, G.5
Devincemo, R.6
Ferrandina, G.7
Piercelli, L.8
Capelli, A.9
Mancuso, S.10
-
9
-
-
0026726483
-
The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs
-
W.F. Matter, R.F. Brown, and C.J. Vlahos The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs Biochem. Biophys. Res. Commun. 186 1992 624 631
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.186
, pp. 624-631
-
-
Matter, W.F.1
Brown, R.F.2
Vlahos, C.J.3
-
10
-
-
0028180143
-
Quercetin mediates the down-regulation of mutant p53 in the human breast cancer cell line MDA-MB468
-
M.A. Avila, J.A. Velasco, J. Cansado, and V. Notario Quercetin mediates the down-regulation of mutant p53 in the human breast cancer cell line MDA-MB468 Cancer Res. 54 1994 2424 2428
-
(1994)
Cancer Res.
, vol.54
, pp. 2424-2428
-
-
Avila, M.A.1
Velasco, J.A.2
Cansado, J.3
Notario, V.4
-
11
-
-
0030842112
-
Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition
-
G. Agullo, L. Gamet-Payrastre, S. Manenti, C. Viala, C. Rémésy, H. Chap, and B. Payrastre Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition Biochem. Pharmacol. 53 1997 1649 1657
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 1649-1657
-
-
Agullo, G.1
Gamet-Payrastre, L.2
Manenti, S.3
Viala, C.4
Rémésy, C.5
Chap, H.6
Payrastre, B.7
-
12
-
-
0032718128
-
Expression of antioxidant proteins in human intestinal Caco-2 cells treated with dietary flavonoids
-
S. Kameoka, P. Leavitt, C. Chang, and S.M. Kuo Expression of antioxidant proteins in human intestinal Caco-2 cells treated with dietary flavonoids Cancer Lett. 146 1999 161 167
-
(1999)
Cancer Lett.
, vol.146
, pp. 161-167
-
-
Kameoka, S.1
Leavitt, P.2
Chang, C.3
Kuo, S.M.4
-
13
-
-
0033050025
-
Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain
-
R. Garcia-Closas, C.A. Gonzalez, A. Agudo, and E. Riboli Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain Cancer Causes Control 10 1999 71 75
-
(1999)
Cancer Causes Control
, vol.10
, pp. 71-75
-
-
Garcia-Closas, R.1
Gonzalez, C.A.2
Agudo, A.3
Riboli, E.4
-
14
-
-
0034807826
-
Dietary agents in cancer prevention: Flavonoids and isoflavonoids
-
D.F. Birt, S. Hendrich, and W. Wang Dietary agents in cancer prevention: flavonoids and isoflavonoids Pharmacol. Ther. 90 2001 157 177
-
(2001)
Pharmacol. Ther.
, vol.90
, pp. 157-177
-
-
Birt, D.F.1
Hendrich, S.2
Wang, W.3
-
15
-
-
0028925089
-
Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study
-
M.G.L. Hertog, D. Kromhout, C. Aravanis, H. Blackburn, R. Buzina, F. Fidanza, S. Giampaoli, A. Jansen, A. Menotti, S. Nedeljkovic, M. Pekkarinen, B.S. Simic, H. Toshima, E.J.M. Feskens, P.C.H. Hollman, and M.B. Katan Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study Arch. Int. Med. 155 1995 381 386
-
(1995)
Arch. Int. Med.
, vol.155
, pp. 381-386
-
-
Hertog, M.G.L.1
Kromhout, D.2
Aravanis, C.3
Blackburn, H.4
Buzina, R.5
Fidanza, F.6
Giampaoli, S.7
Jansen, A.8
Menotti, A.9
Nedeljkovic, S.10
Pekkarinen, M.11
Simic, B.S.12
Toshima, H.13
Feskens, E.J.M.14
Hollman, P.C.H.15
Katan, M.B.16
-
16
-
-
0018079525
-
Mutagenicity of plant flavonoids: Structural requirements for mutagenic activity in Salmonella typhimurium
-
J.T. MacGregor, and L. Jurd Mutagenicity of plant flavonoids: structural requirements for mutagenic activity in Salmonella typhimurium Mut. Res. 54 1978 297 309
-
(1978)
Mut. Res.
, vol.54
, pp. 297-309
-
-
MacGregor, J.T.1
Jurd, L.2
-
17
-
-
0018854928
-
A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds
-
J.P. Brown A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds Mut. Res. 75 1980 243 277
-
(1980)
Mut. Res.
, vol.75
, pp. 243-277
-
-
Brown, J.P.1
-
18
-
-
0034073601
-
Regioselectivity and reversibility of the glutathione conjugation of quercetin quinone methide
-
M.G. Boersma, J. Vervoort, H. Szymusiak, K. Lemanska, B. Tyrakowska, N. Cenas, J. Segura-Aguilar, and I.M.C.M. Rietjens Regioselectivity and reversibility of the glutathione conjugation of quercetin quinone methide Chem. Res. Toxicol. 13 2000 185 191
-
(2000)
Chem. Res. Toxicol.
, vol.13
, pp. 185-191
-
-
Boersma, M.G.1
Vervoort, J.2
Szymusiak, H.3
Lemanska, K.4
Tyrakowska, B.5
Cenas, N.6
Segura-Aguilar, J.7
Rietjens, I.M.C.M.8
-
20
-
-
0035064608
-
Structure-activity study on the quinone/quinone methide chemistry of flavonoids
-
H.M. Awad, M.G. Boersma, S. Boeren, P.J. Van Bladeren, J. Vervoort, and I.M.C.M. Rietjens Structure-activity study on the quinone/quinone methide chemistry of flavonoids Chem. Res. Toxicol. 14 2001 398 408
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 398-408
-
-
Awad, H.M.1
Boersma, M.G.2
Boeren, S.3
Van Bladeren, P.J.4
Vervoort, J.5
Rietjens, I.M.C.M.6
-
21
-
-
0033052299
-
Glutathione-dependent generation of reactive oxygen species by the peroxidase-catalyzed redox cycling of flavonoids
-
G. Galati, T. Chan, B. Wu, and P.J. O'Brien Glutathione-dependent generation of reactive oxygen species by the peroxidase-catalyzed redox cycling of flavonoids Chem. Res. Toxicol. 12 1999 521 525
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 521-525
-
-
Galati, G.1
Chan, T.2
Wu, B.3
O'Brien, P.J.4
-
22
-
-
0037024378
-
Identification of o-quinone/quinone methide metabolites of quercetin in a cellular in vitro system
-
H.M. Awad, M.G. Boersma, S. Boeren, H. van der Woude, J.J. van Zanden, P.J. van Bladeren, J. Vervoort, and I.M.C.M. Rietjens Identification of o-quinone/quinone methide metabolites of quercetin in a cellular in vitro system FEBS Lett. 520 2002 30 34
-
(2002)
FEBS Lett.
, vol.520
, pp. 30-34
-
-
Awad, H.M.1
Boersma, M.G.2
Boeren, S.3
Van Der Woude, H.4
Van Zanden, J.J.5
Van Bladeren, P.J.6
Vervoort, J.7
Rietjens, I.M.C.M.8
-
23
-
-
0141863169
-
Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans
-
H. van der Woude, A. Gliszczynska-Swiglo, K. Struijs, A. Smeets, G.M. Alink, and I.M.C.M. Rietjens Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans Cancer Lett. 200 2003 41 47
-
(2003)
Cancer Lett.
, vol.200
, pp. 41-47
-
-
Van Der Woude, H.1
Gliszczynska-Swiglo, A.2
Struijs, K.3
Smeets, A.4
Alink, G.M.5
Rietjens, I.M.C.M.6
-
24
-
-
0038730962
-
Evidence of covalent binding of the dietary flavonoid quercetin to DNA and protein in human intestinal and hepatic cells
-
T. Walle, T.S. Vincent, and U.K. Walle Evidence of covalent binding of the dietary flavonoid quercetin to DNA and protein in human intestinal and hepatic cells Biochem. Pharmacol. 65 2003 1603 1610
-
(2003)
Biochem. Pharmacol.
, vol.65
, pp. 1603-1610
-
-
Walle, T.1
Vincent, T.S.2
Walle, U.K.3
-
25
-
-
0041307025
-
Quenching of quercetin quinones/quinone methides by different thiolate scavengers: Stability and reversibility of conjugate formation
-
H.M. Awad, M.G. Boersma, S. Boeren, P.J. Van Bladeren, J. Vervoort, and I.M.C.M. Rietjens Quenching of quercetin quinones/quinone methides by different thiolate scavengers: stability and reversibility of conjugate formation Chem. Res. Toxicol. 16 2003 822 831
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 822-831
-
-
Awad, H.M.1
Boersma, M.G.2
Boeren, S.3
Van Bladeren, P.J.4
Vervoort, J.5
Rietjens, I.M.C.M.6
-
27
-
-
0019726446
-
Mutagenicities of 61 flavonoids and 11 related compounds
-
M. Nagao, N. Morita, T. Yahagi, M. Shimizu, M. Kuroyanagi, M. Fukuoka, K. Yoshihira, S. Natori, T. Fujino, and T. Sugimura Mutagenicities of 61 flavonoids and 11 related compounds Environ. Mut. 3 1981 401 419
-
(1981)
Environ. Mut.
, vol.3
, pp. 401-419
-
-
Nagao, M.1
Morita, N.2
Yahagi, T.3
Shimizu, M.4
Kuroyanagi, M.5
Fukuoka, M.6
Yoshihira, K.7
Natori, S.8
Fujino, T.9
Sugimura, T.10
-
28
-
-
8944232918
-
Toxicology and carcinogenesis studies of quercetin (Cas No. 117-39-5) in F344 rats (Feed studies)
-
NI publication No 91-3140, US Department of Health and Human Services, Public Health Service, National Toxicology Program, Research Triangle Park, NC
-
NTP, Toxicology and carcinogenesis studies of quercetin (Cas No. 117-39-5) in F344 rats (Feed studies), NTP technical report (TR-409), NI publication No 91-3140, US Department of Health and Human Services, Public Health Service, National Toxicology Program, Research Triangle Park, NC, 1991.
-
(1991)
NTP Technical Report (TR-409)
-
-
-
29
-
-
77957178533
-
Toxicity and carcinogenicity studies of quercetin, a natural component of foods
-
J.K. Dunnick, and J.R. Hailey Toxicity and carcinogenicity studies of quercetin, a natural component of foods Fundam. Appl. Toxicol. 19 1992 423 431
-
(1992)
Fundam. Appl. Toxicol.
, vol.19
, pp. 423-431
-
-
Dunnick, J.K.1
Hailey, J.R.2
-
30
-
-
0018954540
-
Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium aquilinum)
-
A.M. Pamukcu, S. Yalciner, J.F. Hatcher, and G.T. Bryan Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (Pteridium aquilinum) Cancer Res. 40 1980 3468 3472
-
(1980)
Cancer Res.
, vol.40
, pp. 3468-3472
-
-
Pamukcu, A.M.1
Yalciner, S.2
Hatcher, J.F.3
Bryan, G.T.4
-
31
-
-
0019412478
-
Carcinogenicity examination of quercetin and rutin in ACI rats
-
I. Hirono, I. Ueno, S. Hosaka, H. Takanashi, T. Matsushima, T. Sugimura, and S. Natori Carcinogenicity examination of quercetin and rutin in ACI rats Cancer Lett. 13 1981 15 21
-
(1981)
Cancer Lett.
, vol.13
, pp. 15-21
-
-
Hirono, I.1
Ueno, I.2
Hosaka, S.3
Takanashi, H.4
Matsushima, T.5
Sugimura, T.6
Natori, S.7
-
32
-
-
0020079933
-
Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration
-
K. Morino, N. Matsukura, T. Kawachi, H. Ohgaki, T. Sugimura, and I. Hirono Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration Carcinogenesis 3 1982 93 97
-
(1982)
Carcinogenesis
, vol.3
, pp. 93-97
-
-
Morino, K.1
Matsukura, N.2
Kawachi, T.3
Ohgaki, H.4
Sugimura, T.5
Hirono, I.6
-
33
-
-
0021741760
-
Quercetin: A mutagen, not a carcinogen in Fisher rats
-
G.S. Stoewsand, J.L. Anderson, J.N. Boyd, G. Hrazdina, J.G. Babish, K.M. Walsh, and P. Losco Quercetin: a mutagen, not a carcinogen in Fisher rats J. Toxicol. Environ. Health 14 1984 105 114
-
(1984)
J. Toxicol. Environ. Health
, vol.14
, pp. 105-114
-
-
Stoewsand, G.S.1
Anderson, J.L.2
Boyd, J.N.3
Hrazdina, G.4
Babish, J.G.5
Walsh, K.M.6
Losco, P.7
-
34
-
-
0021025445
-
Effect of quercetin on two-stage carcinogenesis of the rat urinary bladder
-
M. Hirose, S. Fukushima, T. Sakata, M. Inui, and N. Ito Effect of quercetin on two-stage carcinogenesis of the rat urinary bladder Cancer Lett. 21 1983 23 27
-
(1983)
Cancer Lett.
, vol.21
, pp. 23-27
-
-
Hirose, M.1
Fukushima, S.2
Sakata, T.3
Inui, M.4
Ito, N.5
-
35
-
-
0024851499
-
Lack of carcinogenicity of quercetin in F334/DuCrj rats
-
N. Ito, A. Hagiwara, S. Tamano, M. Kagawa, M.A. Shibata, Y. Kurata, and S. Fukushima Lack of carcinogenicity of quercetin in F334/DuCrj rats Jpn. J. Cancer Res. 80 1989 317 325
-
(1989)
Jpn. J. Cancer Res.
, vol.80
, pp. 317-325
-
-
Ito, N.1
Hagiwara, A.2
Tamano, S.3
Kagawa, M.4
Shibata, M.A.5
Kurata, Y.6
Fukushima, S.7
-
36
-
-
0026825965
-
Is quercetin carcinogenic?
-
N. Ito Is quercetin carcinogenic? Jpn. J. Cancer Res. 83 1992 312 313
-
(1992)
Jpn. J. Cancer Res.
, vol.83
, pp. 312-313
-
-
Ito, N.1
-
37
-
-
0028085081
-
Catechol-O-methyltransferase-catalyzed rapid O-methylation of mutagenic flavonoids. Metabolic inactivation as a possible reason for their lack of carcinogenicity in vivo
-
B.T. Zhu, E.L. Ezell, and J.G. Liehr Catechol-O-methyltransferase- catalyzed rapid O-methylation of mutagenic flavonoids. Metabolic inactivation as a possible reason for their lack of carcinogenicity in vivo J. Biol. Chem. 269 1994 292 299
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 292-299
-
-
Zhu, B.T.1
Ezell, E.L.2
Liehr, J.G.3
-
39
-
-
0030050728
-
Inhibition of catechol O-methyltransferase-catalyzed O-methylation of 2- and 4-hydroxyestradiol by quercetin. Possible role in estrogen-induced tumorigenesis
-
B.T. Zhu, and J.G. Liehr Inhibition of catechol O-methyltransferase- catalyzed O-methylation of 2- and 4-hydroxyestradiol by quercetin. Possible role in estrogen-induced tumorigenesis J. Biol. Chem. 271 1996 1357 1363
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1357-1363
-
-
Zhu, B.T.1
Liehr, J.G.2
-
41
-
-
0034068228
-
Role of quinones in toxicology
-
J.L. Bolton, M.A. Trush, T.M. Penning, G. Dryhurst, and T.J. Monks Role of quinones in toxicology Chem. Res. Toxicol. 13 2000 135 160
-
(2000)
Chem. Res. Toxicol.
, vol.13
, pp. 135-160
-
-
Bolton, J.L.1
Trush, M.A.2
Penning, T.M.3
Dryhurst, G.4
Monks, T.J.5
-
42
-
-
0037422461
-
Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin
-
J.J. van Zanden, O. Ben Hamman, M.L.P.S. van Iersel, S. Boeren, N.H.P. Cnubben, M. Lo Bello, J. Vervoort, P.J. van Bladeren, and I.M.C.M. Rietjens Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin Chem. Biol. Interact. 145 2003 139 148
-
(2003)
Chem. Biol. Interact.
, vol.145
, pp. 139-148
-
-
Van Zanden, J.J.1
Ben Hamman, O.2
Van Iersel, M.L.P.S.3
Boeren, S.4
Cnubben, N.H.P.5
Lo Bello, M.6
Vervoort, J.7
Van Bladeren, P.J.8
Rietjens, I.M.C.M.9
-
43
-
-
0032574751
-
Increased skin tumorigenesis in mice lacking pi-class glutathione-S-transferases
-
C.J. Henderson, A.G. Smith, J. Ure, K. Brown, E.J. Bacon, and C.R. Wolf Increased skin tumorigenesis in mice lacking pi-class glutathione-S-transferases Proc. Natl. Acad. Sci. U.S.A. 95 1998 5275 5280
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 5275-5280
-
-
Henderson, C.J.1
Smith, A.G.2
Ure, J.3
Brown, K.4
Bacon, E.J.5
Wolf, C.R.6
-
44
-
-
0031034001
-
Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro
-
D.T. Zava, and G. Duwe Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro Nutr. Cancer 27 1997 31 40
-
(1997)
Nutr. Cancer
, vol.27
, pp. 31-40
-
-
Zava, D.T.1
Duwe, G.2
-
45
-
-
0032170032
-
Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo
-
C.Y. Hsieh, R.C. Santell, S.Z. Haslam, and W.G. Helferich Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo Cancer Res. 58 1998 3833 3838
-
(1998)
Cancer Res.
, vol.58
, pp. 3833-3838
-
-
Hsieh, C.Y.1
Santell, R.C.2
Haslam, S.Z.3
Helferich, W.G.4
-
46
-
-
0031619956
-
Phytochemicals for the prevention of breast and endometrial cancer
-
J.M. Cline, and C.L. Hughes Jr. Phytochemicals for the prevention of breast and endometrial cancer Cancer Treat. Res. 94 1998 107 134
-
(1998)
Cancer Treat. Res.
, vol.94
, pp. 107-134
-
-
Cline, J.M.1
Hughes Jr., C.L.2
-
47
-
-
0030860896
-
Association of soy and fiber consumption with the risk of endometrial cancer
-
M.T. Goodman, L.R. Wilkens, J.H. Hankin, L.C. Lyu, A.H. Wu, and L.N. Kolonel Association of soy and fiber consumption with the risk of endometrial cancer Am. J. Epidemiol. 146 1997 294 306
-
(1997)
Am. J. Epidemiol.
, vol.146
, pp. 294-306
-
-
Goodman, M.T.1
Wilkens, L.R.2
Hankin, J.H.3
Lyu, L.C.4
Wu, A.H.5
Kolonel, L.N.6
-
48
-
-
0035033774
-
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids
-
E.M. Leslie, Q. Mao, C.J. Oleschuk, R.G. Deeley, and S.P. Cole Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids Mol. Pharmacol. 59 2001 1171 1180
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1171-1180
-
-
Leslie, E.M.1
Mao, Q.2
Oleschuk, C.J.3
Deeley, R.G.4
Cole, S.P.5
-
49
-
-
1642385070
-
Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells
-
J.J. van Zanden, L. Geraets, H.M. Wortelboer, P.J. van Bladeren, I.M.C.M. Rietjens, and N.H.P. Cnubben Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells Biochem. Pharmacol. 67 2004 1607 1617
-
(2004)
Biochem. Pharmacol.
, vol.67
, pp. 1607-1617
-
-
Van Zanden, J.J.1
Geraets, L.2
Wortelboer, H.M.3
Van Bladeren, P.J.4
Rietjens, I.M.C.M.5
Cnubben, N.H.P.6
-
50
-
-
12744256734
-
Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
-
J.J. van Zanden, H.M. Wortelboer, S. Bijlsma, A. Punt, M. Usta, P.J. van Bladeren, I.M.C.M. Rietjens, and N.H.P. Cnubben Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2 Biochem. Pharmacol. 69 2005 699 708
-
(2005)
Biochem. Pharmacol.
, vol.69
, pp. 699-708
-
-
Van Zanden, J.J.1
Wortelboer, H.M.2
Bijlsma, S.3
Punt, A.4
Usta, M.5
Van Bladeren, P.J.6
Rietjens, I.M.C.M.7
Cnubben, N.H.P.8
-
51
-
-
18244376403
-
Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters
-
A. Di Pietro, G. Conseil, J.M. Perez-Victoria, G. Dayan, H. Baubichon-Cortay, D. Trompier, E. Steinfels, J.M. Jault, H. de Wet, M. Maitrejean, G. Comte, A. Boumendjel, A.M. Mariotte, C. Dumontet, D.B. McIntosh, A. Goffeau, S. Castanys, F. Gamarro, and D. Barron Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters Cell. Mol. Life Sci. 59 2002 307 322
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, pp. 307-322
-
-
Di Pietro, A.1
Conseil, G.2
Perez-Victoria, J.M.3
Dayan, G.4
Baubichon-Cortay, H.5
Trompier, D.6
Steinfels, E.7
Jault, J.M.8
De Wet, H.9
Maitrejean, M.10
Comte, G.11
Boumendjel, A.12
Mariotte, A.M.13
Dumontet, C.14
McIntosh, D.B.15
Goffeau, A.16
Castanys, S.17
Gamarro, F.18
Barron, D.19
-
52
-
-
2142711101
-
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport
-
S. Zhang, X. Yang, and M.E. Morris Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport Mol. Pharmacol. 65 2004 1208 1216
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 1208-1216
-
-
Zhang, S.1
Yang, X.2
Morris, M.E.3
-
53
-
-
0034119967
-
Expression and localization of multidrug resistant protein MRP2 in rat small intestine
-
A.D. Mottino, T. Hoffman, L. Jennes, and M. Vore Expression and localization of multidrug resistant protein MRP2 in rat small intestine J. Pharmacol. Exp. Ther. 293 2000 717 723
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 717-723
-
-
Mottino, A.D.1
Hoffman, T.2
Jennes, L.3
Vore, M.4
-
54
-
-
0032723724
-
Transport of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo-[4, 5-b]pyridine (PhIP) across the human intestinal Caco-2 cell monolayer: Role of efflux pumps
-
U.K. Walle, and T. Walle Transport of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) across the human intestinal Caco-2 cell monolayer: role of efflux pumps Carcinogenesis 20 1999 2153 2157
-
(1999)
Carcinogenesis
, vol.20
, pp. 2153-2157
-
-
Walle, U.K.1
Walle, T.2
-
55
-
-
0035034532
-
Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats
-
C.G. Dietrich, D.R. de Waart, R. Ottenhoff, I.G. Schoots, and R.P. Elferink Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats Mol. Pharmacol. 59 2001 974 980
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 974-980
-
-
Dietrich, C.G.1
De Waart, D.R.2
Ottenhoff, R.3
Schoots, I.G.4
Elferink, R.P.5
-
59
-
-
0036286160
-
Safety assessment of allylalkoxybenzene derivatives used as flavouring substances - Methyl eugenol and estragole
-
R.L. Smith, T.B. Adams, J. Doull, V.J. Feron, J.L. Goodman, L.J. Marnett, P.S. Portoghese, W.J. Waddell, B.M. Wagner, A.E. Rogers, J. Caldwell, and I.G. Sipes Safety assessment of allylalkoxybenzene derivatives used as flavouring substances - methyl eugenol and estragole Food Chem. Toxicol. 40 2002 851 870
-
(2002)
Food Chem. Toxicol.
, vol.40
, pp. 851-870
-
-
Smith, R.L.1
Adams, T.B.2
Doull, J.3
Feron, V.J.4
Goodman, J.L.5
Marnett, L.J.6
Portoghese, P.S.7
Waddell, W.J.8
Wagner, B.M.9
Rogers, A.E.10
Caldwell, J.11
Sipes, I.G.12
-
60
-
-
0017029682
-
Hepatocarcinogenicity of estragole and 1′-hydroxyestragole in the mouse and mutagenicity of 1′-acetoxyestragole in bacteria
-
N.R. Drinkwater, E.C. Miller, J.A. Miller, and H.C. Pitot Hepatocarcinogenicity of estragole and 1′-hydroxyestragole in the mouse and mutagenicity of 1′-acetoxyestragole in bacteria J. Natl. Cancer Inst. 57 1976 1323 1331
-
(1976)
J. Natl. Cancer Inst.
, vol.57
, pp. 1323-1331
-
-
Drinkwater, N.R.1
Miller, E.C.2
Miller, J.A.3
Pitot, H.C.4
-
61
-
-
0020692513
-
Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole
-
C. Miller, A.B. Swanson, D.H. Phillips, T.L. Fletcher, A. Liem, and J.A. Miller Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole Cancer Res. 43 1983 1124 1134
-
(1983)
Cancer Res.
, vol.43
, pp. 1124-1134
-
-
Miller, C.1
Swanson, A.B.2
Phillips, D.H.3
Fletcher, T.L.4
Liem, A.5
Miller, J.A.6
-
62
-
-
0021856770
-
Further characterisation of the DNA adducts formed by electrophilic esters of the hepatocarcinogens 1′-hydroxysafrole and 1′- hydroxyestragole in vitro and in mouse liver in vivo, including new adducts at C-8 and N-7 of guanine residues
-
R.W. Wiseman, T.R. Fennel, J.A. Miller, and E.C. Miller Further characterisation of the DNA adducts formed by electrophilic esters of the hepatocarcinogens 1′-hydroxysafrole and 1′-hydroxyestragole in vitro and in mouse liver in vivo, including new adducts at C-8 and N-7 of guanine residues Cancer Res. 45 1985 3096 3105
-
(1985)
Cancer Res.
, vol.45
, pp. 3096-3105
-
-
Wiseman, R.W.1
Fennel, T.R.2
Miller, J.A.3
Miller, E.C.4
-
63
-
-
0023241740
-
Structure-activity studies of the hepatocarcinogenicities of alkylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6JXC3H/HeJF1 mice
-
R.W. Wiseman, E.C. Miller, J.A. Miller, and A. Liem Structure-activity studies of the hepatocarcinogenicities of alkylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6JXC3H/HeJF1 mice Cancer Res. 47 1987 2275 2283
-
(1987)
Cancer Res.
, vol.47
, pp. 2275-2283
-
-
Wiseman, R.W.1
Miller, E.C.2
Miller, J.A.3
Liem, A.4
-
64
-
-
0028170840
-
The genotoxic potential in vitro and in vivo of the allyl benzene etheric oils estragole, basil oil and trans-anethole
-
L. Müller, P. Kasper, K. Muller-Tegethoff, and T. Petr The genotoxic potential in vitro and in vivo of the allyl benzene etheric oils estragole, basil oil and trans-anethole Mut. Res. 325 1994 129 136
-
(1994)
Mut. Res.
, vol.325
, pp. 129-136
-
-
Müller, L.1
Kasper, P.2
Muller-Tegethoff, K.3
Petr, T.4
-
65
-
-
0021646473
-
32P-Postlabelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally occurring alkenylbenzenes. I. Adult female CD-1 mice
-
32P-Postlabelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally occurring alkenylbenzenes. I. Adult female CD-1 mice Carcinogenesis 5 1984 1613 1622
-
(1984)
Carcinogenesis
, vol.5
, pp. 1613-1622
-
-
Randerath, K.1
Haglund, R.E.2
Phillips, D.H.3
Reddy, M.V.4
-
66
-
-
0021646474
-
32P-Postlabelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. II. Newborn male B6C3F1 mice
-
32P-Postlabelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. II. Newborn male B6C3F1 mice Carcinogenesis 5 1984 1623 1628
-
(1984)
Carcinogenesis
, vol.5
, pp. 1623-1628
-
-
Phillips, D.1
Reddy, M.V.2
Randerath, K.3
-
68
-
-
0038663111
-
Glucuronidation of 1′-hydroxyestragole (1′-HE) by human UDP-glucuronosyltransferases UGT2B7 and UGT1A9
-
L.V. Iyer, M.N. Ho, W.M. Shinn, W.W. Bradford, M.J. Tanga, S.S. Nath, and C.E. Green Glucuronidation of 1′-hydroxyestragole (1′-HE) by human UDP-glucuronosyltransferases UGT2B7 and UGT1A9 Toxicol. Sci. 73 2003 36 43
-
(2003)
Toxicol. Sci.
, vol.73
, pp. 36-43
-
-
Iyer, L.V.1
Ho, M.N.2
Shinn, W.M.3
Bradford, W.W.4
Tanga, M.J.5
Nath, S.S.6
Green, C.E.7
-
69
-
-
0023543566
-
Metabolism of estragole in rat and mouse and influence of dose size on excretion of the proximate carcinogen 1′-hydroxyestragole
-
A. Anthony, J. Caldwell, A.J. Hutt, and R.L. Smith Metabolism of estragole in rat and mouse and influence of dose size on excretion of the proximate carcinogen 1′-hydroxyestragole Food Chem. Toxicol. 25 1987 799 806
-
(1987)
Food Chem. Toxicol.
, vol.25
, pp. 799-806
-
-
Anthony, A.1
Caldwell, J.2
Hutt, A.J.3
Smith, R.L.4
-
70
-
-
0019421614
-
Dose-dependent conversion of estragole in the rat and mouse to the carcinogenic metabolite 1-hydroxyestragole
-
A. Zangouras, J. Caldwell, A.J. Hutt, and R.L. Smith Dose-dependent conversion of estragole in the rat and mouse to the carcinogenic metabolite 1-hydroxyestragole Biochem. Pharmacol. 30 1981 1383 1386
-
(1981)
Biochem. Pharmacol.
, vol.30
, pp. 1383-1386
-
-
Zangouras, A.1
Caldwell, J.2
Hutt, A.J.3
Smith, R.L.4
-
71
-
-
0018379379
-
The mutagenicities of safrole, estragole, trans-anethole and some of their known or possible metabolites for Salmonella typhimurium mutants
-
A.B. Swanson, D.D. Chambliss, J.C. Blanquist, E.C. Miller, and J.A. Miller The mutagenicities of safrole, estragole, trans-anethole and some of their known or possible metabolites for Salmonella typhimurium mutants Mut. Res. 60 1979 143 153
-
(1979)
Mut. Res.
, vol.60
, pp. 143-153
-
-
Swanson, A.B.1
Chambliss, D.D.2
Blanquist, J.C.3
Miller, E.C.4
Miller, J.A.5
-
72
-
-
0028978705
-
32P-Postlabelling analysis of adducts formed between DNA and safrole 2′,3′-epoxide: Absence of adduct formation in vivo
-
32P-Postlabelling analysis of adducts formed between DNA and safrole 2′,3′-epoxide: absence of adduct formation in vivo Toxicol. Lett. 75 1995 201 207
-
(1995)
Toxicol. Lett.
, vol.75
, pp. 201-207
-
-
Qato, M.K.1
Guenthner, T.M.2
-
73
-
-
0029809858
-
Covalent binding to DNA in vitro of 2′,3′-oxides derived from allylbenzene analogs
-
G. Luo, and T.M. Guenthner Covalent binding to DNA in vitro of 2′,3′-oxides derived from allylbenzene analogs Drug Metab. Dispos. 24 1996 1020 1027
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 1020-1027
-
-
Luo, G.1
Guenthner, T.M.2
-
74
-
-
0035819912
-
Investigation of the role of the 2′,3′-epoxidation pathway in the bioactivation and genotoxicity of dietary allylbenzene analogs
-
T.M. Guenthner, and G. Luo Investigation of the role of the 2′,3′-epoxidation pathway in the bioactivation and genotoxicity of dietary allylbenzene analogs Toxicology 160 2001 47 58
-
(2001)
Toxicology
, vol.160
, pp. 47-58
-
-
Guenthner, T.M.1
Luo, G.2
-
76
-
-
0026459531
-
Comparative induction of unscheduled DNA synthesis in cultured rat hepatocytes by allylbenzenes and their 1′-hydroxy metabolites
-
V.S.W. Chan, and J. Caldwell Comparative induction of unscheduled DNA synthesis in cultured rat hepatocytes by allylbenzenes and their 1′-hydroxy metabolites Food Chem. Toxicol. 30 1992 831 836
-
(1992)
Food Chem. Toxicol.
, vol.30
, pp. 831-836
-
-
Chan, V.S.W.1
Caldwell, J.2
-
77
-
-
0025113923
-
Structure-specificity of the genotoxicity of some naturally occuring alkenylbenzenes determined by the unscheduled DNA synthesis assay in rat hepatocytes
-
A.J. Howes, V.S.W. Chan, and J. Caldwell Structure-specificity of the genotoxicity of some naturally occuring alkenylbenzenes determined by the unscheduled DNA synthesis assay in rat hepatocytes Food Chem. Toxicol. 28 1990 537 542
-
(1990)
Food Chem. Toxicol.
, vol.28
, pp. 537-542
-
-
Howes, A.J.1
Chan, V.S.W.2
Caldwell, J.3
-
78
-
-
15044355842
-
Formation of alkenylbenzene macromolecular adducts in human fibroblast V79 cells transfected with human sulfotransferases
-
P. Stening, I. Gardner, J.E. Kenna, M.W.H. Coughtrie, and J. Caldwell Formation of alkenylbenzene macromolecular adducts in human fibroblast V79 cells transfected with human sulfotransferases Human Exp. Toxicol. 16 1997 62
-
(1997)
Human Exp. Toxicol.
, vol.16
, pp. 62
-
-
Stening, P.1
Gardner, I.2
Kenna, J.E.3
Coughtrie, M.W.H.4
Caldwell, J.5
-
79
-
-
0017286721
-
Metabolism of alkylbenzene derivatives in the rat. II. Eugenol and isoeugenol methyl ethers
-
E. Solheim, and R.R. Scheline Metabolism of alkylbenzene derivatives in the rat. II. Eugenol and isoeugenol methyl ethers Xenobiotica 6 1973 137 150
-
(1973)
Xenobiotica
, vol.6
, pp. 137-150
-
-
Solheim, E.1
Scheline, R.R.2
-
80
-
-
0019210482
-
Biotransformation of allylbenzene analogues in vivo and in vitro through the epoxide diol pathway
-
M. Delaforge, P. Janiaud, O. Levi, and J.P. Moritoz Biotransformation of allylbenzene analogues in vivo and in vitro through the epoxide diol pathway Xenobiotica 10 1980 737 744
-
(1980)
Xenobiotica
, vol.10
, pp. 737-744
-
-
Delaforge, M.1
Janiaud, P.2
Levi, O.3
Moritoz, J.P.4
-
81
-
-
0012092005
-
The metabolic activation and carcinogenicity of alkenylbenzenes that occur naturally in many spices
-
H.F. Stich CRC Press Boca Raton
-
J.A. Miller, E.C. Miller, and D.H. Phillips The metabolic activation and carcinogenicity of alkenylbenzenes that occur naturally in many spices H.F. Stich Carcinogens and Mutagens in the Environment vol. I 1982 CRC Press Boca Raton 83 96
-
(1982)
Carcinogens and Mutagens in the Environment
, vol.1
, pp. 83-96
-
-
Miller, J.A.1
Miller, E.C.2
Phillips, D.H.3
-
82
-
-
0014750455
-
Carcinogenicity testing of selected food additives by parenteral administration to infant swiss mice
-
S.S. Epstein, D. Fujii, J. Andrea, and N. Mantel Carcinogenicity testing of selected food additives by parenteral administration to infant swiss mice Toxicol. Appl. Pharmacol. 16 1970 321 334
-
(1970)
Toxicol. Appl. Pharmacol.
, vol.16
, pp. 321-334
-
-
Epstein, S.S.1
Fujii, D.2
Andrea, J.3
Mantel, N.4
-
83
-
-
0015591485
-
1′-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse
-
P. Borchert, J.A. Miller, E.C. Miller, and T.K. Shires 1′-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse Cancer Res. 33 1973 590 600
-
(1973)
Cancer Res.
, vol.33
, pp. 590-600
-
-
Borchert, P.1
Miller, J.A.2
Miller, E.C.3
Shires, T.K.4
-
84
-
-
0022558710
-
32P-Postlabelling assay in mice of transplacental DNA damage induced by environmental carcinogens safrole, 4-aminobiphenyl, benzo[a]pyrene
-
32P- Postlabelling assay in mice of transplacental DNA damage induced by environmental carcinogens safrole, 4-aminobiphenyl, benzo[a]pyrene Cancer Res. 46 1986 3046 3054
-
(1986)
Cancer Res.
, vol.46
, pp. 3046-3054
-
-
Lu, L.J.W.1
Disher, R.M.2
Reddy, M.V.3
Randerath, K.4
-
85
-
-
0018598175
-
Transplacental and lactational carcinogenesis by safrole
-
S.D. Vesselinovitch, K.V. Rao, and N. Mihailovich Transplacental and lactational carcinogenesis by safrole Cancer Res. 39 1979 4378 4380
-
(1979)
Cancer Res.
, vol.39
, pp. 4378-4380
-
-
Vesselinovitch, S.D.1
Rao, K.V.2
Mihailovich, N.3
-
86
-
-
0016742929
-
Gastrointestinal absorption in the rat of anisole, trans-anethole, butyl-hydroxyanisole and safrole
-
P. Fritsch, G. de Saint Blanque, and R. Deranche Gastrointestinal absorption in the rat of anisole, trans-anethole, butyl-hydroxyanisole and safrole Food Cosmet. Toxicol. 13 1975 359 363
-
(1975)
Food Cosmet. Toxicol.
, vol.13
, pp. 359-363
-
-
Fritsch, P.1
De Saint Blanque, G.2
Deranche, R.3
-
87
-
-
0016769907
-
Effect of anisole, anethole, butyl-hydroxyanisole and safrole on intestinal absorption in the rat
-
P. Fritsch, Y. Lamboeuf, and G. de Saint Blanquet Effect of anisole, anethole, butyl-hydroxyanisole and safrole on intestinal absorption in the rat Toxicology 4 1975 341 346
-
(1975)
Toxicology
, vol.4
, pp. 341-346
-
-
Fritsch, P.1
Lamboeuf, Y.2
De Saint Blanquet, G.3
-
88
-
-
0028285123
-
Evidence that 4-allyl-o-quinones spontaneously rearrange to their more electrophilic quinone methides: Potential bioactivation mechanism for the hepatocarcinogen safrole
-
J.L. Bolton, N.M. Acay, and V. Vukomanovic Evidence that 4-allyl-o-quinones spontaneously rearrange to their more electrophilic quinone methides: potential bioactivation mechanism for the hepatocarcinogen safrole Chem. Res. Toxicol. 7 1994 443 450
-
(1994)
Chem. Res. Toxicol.
, vol.7
, pp. 443-450
-
-
Bolton, J.L.1
Acay, N.M.2
Vukomanovic, V.3
-
89
-
-
0028899066
-
The influence of 4-alkyl substituents on the formation and reactivity of 2-methoxy-quinone methides: Evidence that extended π-conjugation dramatically stabilizes the quinone methide formed from eugenol
-
J.L. Bolton, E. Comeau, and V. Vukomanovic The influence of 4-alkyl substituents on the formation and reactivity of 2-methoxy-quinone methides: evidence that extended π-conjugation dramatically stabilizes the quinone methide formed from eugenol Chem. Biol. Interact. 95 1995 279 290
-
(1995)
Chem. Biol. Interact.
, vol.95
, pp. 279-290
-
-
Bolton, J.L.1
Comeau, E.2
Vukomanovic, V.3
-
90
-
-
0027272606
-
Flavor constituents in cola drinks induce hepatic DNA adducts in adult and fetal mice
-
K.P. Randerath, K.L. Putman, and E. Randerath Flavor constituents in cola drinks induce hepatic DNA adducts in adult and fetal mice Biochem. Biophys. Res. Commun. 192 1993 61 68
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.192
, pp. 61-68
-
-
Randerath, K.P.1
Putman, K.L.2
Randerath, E.3
-
91
-
-
0021054404
-
Strong evidence from studies with brachimorphic mice and pentachlorophenol that 1′-sulphooxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1′-hydroxysafrole in mouse liver
-
E.W. Boberg, E.C. Miller, J.A. Miller, A. Poland, and A. Liem Strong evidence from studies with brachimorphic mice and pentachlorophenol that 1′-sulphooxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1′-hydroxysafrole in mouse liver Cancer Res. 43 1983 5163 5173
-
(1983)
Cancer Res.
, vol.43
, pp. 5163-5173
-
-
Boberg, E.W.1
Miller, E.C.2
Miller, J.A.3
Poland, A.4
Liem, A.5
-
92
-
-
4644226386
-
Human cytochrome P450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1′-hydroxysafrole
-
S.M.F. Jeurissen, J.J.P. Bogaards, H.M. Awad, M.G. Boersma, W. Brand, Y.C. Fiamegos, T.A. van Beek, G.M. Alink, E.J.R. Sudhölter, N.H.P. Cnubben, and I.M.C.M. Rietjens Human cytochrome P450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1′-hydroxysafrole Chem. Res. Toxicol. 17 2004 1245 1250
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 1245-1250
-
-
Jeurissen, S.M.F.1
Bogaards, J.J.P.2
Awad, H.M.3
Boersma, M.G.4
Brand, W.5
Fiamegos, Y.C.6
Van Beek, T.A.7
Alink, G.M.8
Sudhölter, E.J.R.9
Cnubben, N.H.P.10
Rietjens, I.M.C.M.11
-
93
-
-
4243125326
-
Identification of the main human cytochrome P450 enzymes involved in safrole 1′-hydroxylation
-
Y.F. Ueng, C.H. Hsieh, M.J. Don, C.W. Chi, and L.K. Ho Identification of the main human cytochrome P450 enzymes involved in safrole 1′- hydroxylation Chem. Res. Toxicol. 17 2004 1151 1156
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 1151-1156
-
-
Ueng, Y.F.1
Hsieh, C.H.2
Don, M.J.3
Chi, C.W.4
Ho, L.K.5
-
94
-
-
0032793249
-
Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
-
M. Ingelman-Sundberg, M. Oscarson, and R.A. McLellan Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment Trend Pharmacol. Sci. 20 1999 342 349
-
(1999)
Trend Pharmacol. Sci.
, vol.20
, pp. 342-349
-
-
Ingelman-Sundberg, M.1
Oscarson, M.2
McLellan, R.A.3
-
95
-
-
0029055831
-
Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
-
B.J. Roberts, S.E. Shoaf, and B.J. Song Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats Biochem. Pharmacol. 49 1995 1665 1673
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 1665-1673
-
-
Roberts, B.J.1
Shoaf, S.E.2
Song, B.J.3
-
96
-
-
0032818506
-
Expression of cytochromes P450 2E1, 3A4 and 1A1/1A2 in growing and confluent human HepG2 hepatoma cells - Effect of ethanol
-
E. Alexandre, P. David, C. Viollon, P. Wolf, D. Jaeck, A. Azimzadeh, L. Nicod, K. Boudjema, and L. Richert Expression of cytochromes P450 2E1, 3A4 and 1A1/1A2 in growing and confluent human HepG2 hepatoma cells - effect of ethanol Toxicol. In Vitro 13 1999 427 435
-
(1999)
Toxicol. in Vitro
, vol.13
, pp. 427-435
-
-
Alexandre, E.1
David, P.2
Viollon, C.3
Wolf, P.4
Jaeck, D.5
Azimzadeh, A.6
Nicod, L.7
Boudjema, K.8
Richert, L.9
-
97
-
-
0035118826
-
Induction of CYP2C genes in human hepatocytes in primary culture
-
S. Gerbal-Chaloin, J.-M. Pascussi, L. Pichard-Garcia, M. Daujat, F. Waechter, J.-M. Fabre, N. Carrere, and P. Maurel Induction of CYP2C genes in human hepatocytes in primary culture Drug Metab. Dispos. 29 2001 242 251
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 242-251
-
-
Gerbal-Chaloin, S.1
Pascussi, J.-M.2
Pichard-Garcia, L.3
Daujat, M.4
Waechter, F.5
Fabre, J.-M.6
Carrere, N.7
Maurel, P.8
-
98
-
-
0034760929
-
Cytochrome P450 activity in control and induced long-term cultures of rat hepatocyte spheroids
-
A.J.M. Walker, and A.J.M. Woodrooffe Cytochrome P450 activity in control and induced long-term cultures of rat hepatocyte spheroids Toxicol. In Vitro 15 2001 713 719
-
(2001)
Toxicol. in Vitro
, vol.15
, pp. 713-719
-
-
Walker, A.J.M.1
Woodrooffe, A.J.M.2
-
99
-
-
0037194641
-
Frequent occurrence of CYP2D6*10 duplication allele in a Japanese population
-
Y. Mitsunaga, T. Kubota, A. Ishiguro, Y. Yamada, H. Sasaki, K. Chiba, and T. Iga Frequent occurrence of CYP2D6*10 duplication allele in a Japanese population Mut. Res. 505 2002 83 85
-
(2002)
Mut. Res.
, vol.505
, pp. 83-85
-
-
Mitsunaga, Y.1
Kubota, T.2
Ishiguro, A.3
Yamada, Y.4
Sasaki, H.5
Chiba, K.6
Iga, T.7
-
100
-
-
0034638766
-
Pharmacogenetics and adverse drug reactions
-
U.A. Meyer Pharmacogenetics and adverse drug reactions Lancet 356 2000 1667 1671
-
(2000)
Lancet
, vol.356
, pp. 1667-1671
-
-
Meyer, U.A.1
|