Methyleugenol genotoxicity in the Fischer 344 rat using the Comet assay and pathway-focused gene expression profiling

Toxicological Sciences

Volumn 123, Issue 1, 2011, Pages 103-112

  Ding, Wei ^a   Levy, Dan D ^b   Bishop, Michelle E ^a   Lascelles, E Lyn Cook ^a   Kulkarni, Rohan ^a   Chang, Ching We ^a   Aidoo, Anane ^a   Manjanatha, Mugimane G ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Comet assay; Gene expression; Genotoxicity; Methyl methanesulfonate; Methyleugenol; Oxidative DNA damage

Indexed keywords

DNA GLYCOSYLTRANSFERASE; METHYLEUGENOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER; BONE MARROW; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOTOXICITY; KIDNEY; LIVER; LUNG; MALE; NONHUMAN; RAT;

ANIMALS; BONE MARROW CELLS; COMET ASSAY; DEOXYRIBONUCLEASES, TYPE III SITE-SPECIFIC; DNA; DNA DAMAGE; DNA REPAIR; EUGENOL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LIVER; MALE; MUTAGENS; OXIDATION-REDUCTION; RATS; RATS, INBRED F344; URINARY BLADDER;

MUS; RATTUS; RODENTIA;

EID: 80052486079     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr153     Document Type: Article

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