Cytochrome P450 mediated bioactivation of methyleugenol to 1'-hydroxymethyleugenol in Fischer 344 rat and human liver microsomes

Carcinogenesis

Volumn 18, Issue 9, 1997, Pages 1775-1783

  Gardner, Iain ^a   Wakazono, Hiroshi ^a   Bergin, Pauline ^a   De Waziers, Isabelle ^b   Beaune, Phillippe ^b   Kenna, J Gerald ^a   Caldwell, John ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; CARCINOGEN; CYTOCHROME P450; DEXAMETHASONE; EUGENOL; FURAFYLLINE; METHYL GROUP; PHENOBARBITAL; TOLBUTAMIDE; TROLEANDOMYCIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; EUGENOL; HUMANS; HYDROXYLATION; ISOENZYMES; MALE; MICROSOMES, LIVER; RATS; RATS, INBRED F344;

EID: 0031410088     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.9.1775     Document Type: Article

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