Convection-enhanced delivery to the central nervous system

Journal of Neurosurgery

Volumn 122, Issue 3, 2015, Pages 697-706

  Lonser, Russell R ^a,b   Sarntinoranont, Malisa ^c   Morrison, Paul F ^d   Oldfield, Edward H ^b,e  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Bulk flow; Central nervous system; Convection enhanced delivery; Drug delivery; Technique

Indexed keywords

BLOOD BRAIN BARRIER; BRAIN EDEMA; CENTRAL NERVOUS SYSTEM; CONVECTION ENHANCED DRUG DELIVERY SYSTEM; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG SAFETY; EXTRACELLULAR FLUID; EXTRACELLULAR SPACE; HUMAN; HYDRAULIC CONDUCTIVITY; INFUSION SYSTEM; MATHEMATICAL MODEL; MOLECULAR WEIGHT; NONHUMAN; PERIPHERAL INFUSION CATHETER; PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; SYSTEMIC CIRCULATION; TISSUE PERFUSION; VOLUME OF DISTRIBUTION; WHITE MATTER; BIOPHYSICS; INJECTION; THERMODYNAMICS;

BIOPHYSICS; CENTRAL NERVOUS SYSTEM; CONVECTION; DRUG DELIVERY SYSTEMS; HUMANS; INJECTIONS;

EID: 84927965748     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2014.10.JNS14229     Document Type: Review

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