Convection-enhanced delivery of topotecan into diffuse intrinsic brainstem tumors in children

Journal of Neurosurgery: Pediatrics

Volumn 11, Issue 3, 2013, Pages 289-295

  Anderson, Richard C E ^a   Kennedy, Benjamin ^a   Yanes, Candix L ^a   Garvin, James ^a   Needle, Michael ^a   Canoll, Peter ^b   Feldstein, Neil A ^a   Bruce, Jeffrey N ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NONE   (United States)

Author keywords

Brainstem tumor; Convection enhanced delivery; Oncology; Pediatric neurosurgery; Pontine glioma; Topotecan

Indexed keywords

DEXAMETHASONE; TOPOTECAN;

ARTICLE; BRAIN STEM TUMOR; CANCER RADIOTHERAPY; CANCER SURVIVAL; CASE REPORT; CHILD; CONVECTION ENHANCED DELIVERY; CRANIAL NERVE PARALYSIS; DRUG DELIVERY SYSTEM; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEASIBILITY STUDY; FEMALE; GLIOBLASTOMA; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT SELECTION; PILOT STUDY; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; PRIORITY JOURNAL; STEREOTACTIC BIOPSY; TUMOR VOLUME;

ANTINEOPLASTIC AGENTS; BIOPSY; BRAIN; BRAIN STEM NEOPLASMS; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; CONVECTION; DRUG DELIVERY SYSTEMS; FATAL OUTCOME; FEMALE; GAIT DISORDERS, NEUROLOGIC; GLIOMA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KARNOFSKY PERFORMANCE STATUS; MAGNETIC RESONANCE IMAGING; NERVOUS SYSTEM DISEASES; TOPOTECAN; TREATMENT OUTCOME;

EID: 84874709507     PISSN: 19330707     EISSN: 19330715     Source Type: Journal    
DOI: 10.3171/2012.10.PEDS12142     Document Type: Article

References (36)

1. Albright AL, Price RA, Guthkelch AN: Brain stem gliomas of children. A clinicopathological study. Cancer 52:2313-2319, 1983.
2. Allen JC, Siffert J: Contemporary chemotherapy issues for children with brainstem gliomas. Pediatr Neurosurg 24:98- 102, 1996.
3. Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH: Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci U S A 91:2076-2080, 1994.
4. Bruce JN, Falavigna A, Johnson JP, Hall JS, Birch BD, Yoon JT, et al: Intracerebral clysis in a rat glioma model. Neurosurgery 46:683-691, 2000.
5. Bruce JN, Fine RL, Canoll P, Yun J, Kennedy BC, Rosenfeld SS, et al: Regression of recurrent malignant gliomas with convection- enhanced delivery of topotecan. Neurosurgery 69: 1272-1280, 2011.
6. Frazier JL, Lee J, Thomale UW, Noggle JC, Cohen KJ, Jallo GI: Treatment of diffuse intrinsic brainstem gliomas: failed approaches and future strategies. A review. J Neurosurg Pediatr 3:259-269, 2009.
7. Friedman HS, Kerby T, Fields S, Zilisch JE, Graden D, McLendon RE, et al: Topotecan treatment of adults with primary malignant glioma. Cancer 85:1160-1165, 1999.
8. Gerstner ER, Fine RL: Increased permeability of the bloodbrain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigm. J Clin Oncol 25:2306-2312, 2007.
9. Groothuis DR, Benalcazar H, Allen CV, Wise RM, Dills C, Dobrescu C, et al: Comparison of cytosine arabinoside delivery to rat brain by intravenous, intrathecal, intraventricular and intraparenchymal routes of administration. Brain Res 856:281-290, 2000.
10. Hargrave D, Bartels U, Bouffet E: Diffuse brainstem glioma in children: critical review of clinical trials. Lancet Oncol 7: 241-248, 2006.
11. Iyer RR, Butman JA, Walbridge S, Gai ND, Heiss JD, Lonser RR: Tracking accuracy of T2- and diffusion-weighted magnetic resonance imaging for infusate distribution by convection- enhanced delivery. Laboratory investigation. J Neurosurg 115:474-480, 2011.
12. Kaiser MG, Parsa AT, Fine RL, Hall JS, Chakrabarti I, Bruce JN: Tissue distribution and antitumor activity of topotecan delivered by intracerebral clysis in a rat glioma model. Neurosurgery 47:1391-1399, 2000.
13. Khatua S, Moore KR, Vats TS, Kestle JR: Diffuse intrinsic pontine glioma-current status and future strategies. Childs Nerv Syst 27:1391-1397, 2011.
14. Kunwar S: Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies. Acta Neurochir Suppl 88:105-111, 2003.
15. Langer R: New methods of drug delivery. Science 249:1527- 1533, 1990.
16. Laske DW, Youle RJ, Oldfield EH: Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors. Nat Med 3:1362-1368, 1997.
17. Lonser RR, Warren KE, Butman JA, Quezado Z, Robison RA, Walbridge S, et al: Real-time image-guided direct convective perfusion of intrinsic brainstem lesions. Technical note. J Neurosurg 107:190-197, 2007.
18. Morrison PF, Chen MY, Chadwick RS, Lonser RR, Oldfield EH: Focal delivery during direct infusion to brain: role of flow rate, catheter diameter, and tissue mechanics. Am J Physiol 277:R1218-R1229, 1999.
19. Murad GJ, Walbridge S, Morrison PF, Garmestani K, Degen JW, Brechbiel MW, et al: Real-time, image-guided, convection- enhanced delivery of interleukin 13 bound to pseudomonas exotoxin. Clin Cancer Res 12:3145-3151, 2006.
20. Murad GJ, Walbridge S, Morrison PF, Szerlip N, Butman JA, Oldfield EH, et al: Image-guided convection-enhanced delivery of gemcitabine to the brainstem. J Neurosurg 106:351- 356, 2007.
21. Occhiogrosso G, Edgar MA, Sandberg DI, Souweidane MM: Prolonged convection-enhanced delivery into the rat brainstem. Neurosurgery 52:388-394, 2003.
22. Pardridge WM: Drug delivery to the brain. J Cereb Blood Flow Metab 17:713-731, 1997.
23. Patel SJ, Shapiro WR, Laske DW, Jensen RL, Asher AL, Wessels BW, et al: Safety and feasibility of convection-enhanced delivery of Cotara for the treatment of malignant glioma: initial experience in 51 patients. Neurosurgery 56:1243-1253, 2005.
24. Pierre-Kahn A, Hirsch JF, Vinchon M, Payan C, Sainte-Rose C, Renier D, et al: Surgical management of brain-stem tumors in children: results and statistical analysis of 75 cases. J Neurosurg 79:845-852, 1993.
25. Pöpperl G, Goldbrunner R, Gildehaus FJ, Kreth FW, Tanner P, Holtmannspötter M, et al: O-(2-[18F]fluoroethyl)-L-tyrosine PET for monitoring the effects of convection-enhanced delivery of paclitaxel in patients with recurrent glioblastoma. Eur J Nucl Med Mol Imaging 32:1018-1025, 2005.
26. Rand RW, Kreitman RJ, Patronas N, Varricchio F, Pastan I, Puri RK: Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma. Clin Cancer Res 6:2157-2165, 2000.
27. Saito R, Sonoda Y, Kumabe T, Nagamatsu K, Watanabe M, Tominaga T: Regression of recurrent glioblastoma infiltrating the brainstem after convection-enhanced delivery of nimustine hydrochloride. Case report. J Neurosurg Pediatr 7: 522-526, 2011.
28. Sampson JH, Akabani G, Archer GE, Bigner DD, Berger MS, Friedman AH, et al: Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J Neurooncol 65:27-35, 2003.
29. Sandberg DI, Edgar MA, Souweidane MM: Convection-enhanced delivery into the rat brainstem. J Neurosurg 96:885- 891, 2002.
30. Thomale UW, Tyler B, Renard V, Dorfman B, Chacko VP, Carson BS, et al: Neurological grading, survival, MR imaging, and histological evaluation in the rat brainstem glioma model. Childs Nerv Syst 25:433-441, 2009.
31. Thomale UW, Tyler B, Renard VM, Dorfman B, Guarnieri M, Haberl HE, et al: Local chemotherapy in the rat brainstem with multiple catheters: a feasibility study. Childs Nerv Syst 25:21-28, 2009.
32. Voges J, Reszka R, Gossmann A, Dittmar C, Richter R, Garlip G, et al: Imaging-guided convection-enhanced delivery and gene therapy of glioblastoma. Ann Neurol 54:479-487, 2003.
33. Walker DA, Punt JA, Sokal M: Clinical management of brain stem glioma. Arch Dis Child 80:558-564, 1999.
34. Weber FW, Floeth F, Asher A, Bucholz R, Berger M, Prados M, et al: Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma. Acta Neurochir Suppl 88:93- 103, 2003.
35. Yang W, Barth RF, Wu G, Bandyopadhyaya AK, Thirumamagal BT, Tjarks W, et al: Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas. Appl Radiat Isot 61:981-985, 2004.
36. Yin D, Richardson RM, Fiandaca MS, Bringas J, Forsayeth J, Berger MS, et al: Cannula placement for effective convectionenhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics. Laboratory investigation. J Neurosurg 113:240-248, 2010.