Direct interstitial infusion of NK1-targeted neurotoxin into the spinal cord: A computational model

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 285, Issue 1 54-1, 2003, Pages

  Sarntinoranont, Malisa ^a,d   Iadarola, Michael J ^b   Lonser, Russell R ^c   Morrison, Paul F ^a  

^a Office of Research Services   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Convection; Convection enhanced delivery; Finite element method; Intraparenchymal infusions; Pain therapy; Pharmacodynamic model

Indexed keywords

DIPHTHERIA TOXIN; NEUROKININ 1 RECEPTOR; NEUROTOXIN; PEPTIDASE; SUBSTANCE P; SUBSTANCE P DIPHTHERIA TOXIN FUSION PROTEIN; SUBSTANCE P RECEPTOR; UNCLASSIFIED DRUG;

ANISOTROPY; ARTICLE; CHRONIC PAIN; DIFFUSION; DRUG CYTOTOXICITY; DRUG INFUSION; DRUG TRANSPORT; FINITE ELEMENT ANALYSIS; FLOW KINETICS; HUMAN; HYDROLYSIS; INTERSTITIUM; INTRACELLULAR TRANSPORT; PHARMACODYNAMICS; PRIORITY JOURNAL; RECEPTOR DENSITY; SPINAL CORD; WHITE MATTER;

EID: 0038376039     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00472.2002     Document Type: Article

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