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Volumn 30, Issue 5, 2015, Pages 869-877

Genomewide comprehensive analysis reveals critical cooperation between smad and c-Fos in RANKL-induced osteoclastogenesis

Author keywords

Cell tissue signaling; Cytokines; Molecular pathways; Osteoclast; Transcription factors

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; NUCLEAR FACTOR OF ACTIVATED T CELL CYTOPLASMIC 1; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C FOS; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR NFAT; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CHROMATIN; NFATC1 PROTEIN, MOUSE; PROTEIN BINDING; SMAD PROTEIN;

EID: 84927747957     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2418     Document Type: Article
Times cited : (29)

References (37)
  • 1
    • 34748847496 scopus 로고    scopus 로고
    • Signaling axis in osteoclast biology and therapeutic targeting in the RANKL/RANK/OPG system
    • Tanaka S,. Signaling axis in osteoclast biology and therapeutic targeting in the RANKL/RANK/OPG system. Am J Nephrol. 2007; 27 (5): 466-478.
    • (2007) Am J Nephrol. , vol.27 , Issue.5 , pp. 466-478
    • Tanaka, S.1
  • 2
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 1998; 93 (2): 165-176.
    • (1998) Cell. , vol.93 , Issue.2 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3
  • 3
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ,. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev. 1999; 20 (3): 345-357.
    • (1999) Endocr Rev. , vol.20 , Issue.3 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3    Jimi, E.4    Gillespie, M.T.5    Martin, T.J.6
  • 4
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor,is identical to TRANCE/RANKL
    • Yasuda H, Shima N, Nakagawa N, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor,is identical to TRANCE/RANKL. Proc Natl Acad Sci U S.A. 1998; 95 (7): 3597-3602.
    • (1998) Proc Natl Acad Sci U S.A. , vol.95 , Issue.7 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3
  • 5
    • 80055018787 scopus 로고    scopus 로고
    • Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1
    • Yasui T, Hirose J, Tsutsumi S, Nakamura K, Aburatani H, Tanaka S,. Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1. J Bone Miner Res. 2011; 26 (11): 2665-2671.
    • (2011) J Bone Miner Res. , vol.26 , Issue.11 , pp. 2665-2671
    • Yasui, T.1    Hirose, J.2    Tsutsumi, S.3    Nakamura, K.4    Aburatani, H.5    Tanaka, S.6
  • 6
    • 0347296131 scopus 로고    scopus 로고
    • The possible role of TGF-beta-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro
    • Fox SW, Haque SJ, Lovibond AC, Chambers TJ,. The possible role of TGF-beta-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro. J Immunol. 2003; 170 (7): 3679-3687.
    • (2003) J Immunol. , vol.170 , Issue.7 , pp. 3679-3687
    • Fox, S.W.1    Haque, S.J.2    Lovibond, A.C.3    Chambers, T.J.4
  • 7
    • 0028179120 scopus 로고
    • The TGF-beta family and its composite receptors
    • Massague J, Attisano L, Wrana JL,. The TGF-beta family and its composite receptors. Trends Cell Biol. 1994; 4 (5): 172-178.
    • (1994) Trends Cell Biol. , vol.4 , Issue.5 , pp. 172-178
    • Massague, J.1    Attisano, L.2    Wrana, J.L.3
  • 8
    • 48449086316 scopus 로고    scopus 로고
    • A master of all T cell trades
    • Li MO, Flavell RA,. A master of all T cell trades. Cell. 2008; 134 (3): 392-404.
    • (2008) Cell. , vol.134 , Issue.3 , pp. 392-404
    • Li, M.O.1    Flavell, R.A.2
  • 9
    • 0029940972 scopus 로고    scopus 로고
    • Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily
    • Graff JM, Bansal A, Melton DA,. Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily. Cell. 1996; 85 (4): 479-487.
    • (1996) Cell. , vol.85 , Issue.4 , pp. 479-487
    • Graff, J.M.1    Bansal, A.2    Melton, D.A.3
  • 10
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE,. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature. 2003; 425 (6958): 577-584.
    • (2003) Nature. , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 11
    • 0029829230 scopus 로고    scopus 로고
    • A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
    • Baker JC, Harland RM,. A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes Dev. 1996; 10 (15): 1880-1889.
    • (1996) Genes Dev. , vol.10 , Issue.15 , pp. 1880-1889
    • Baker, J.C.1    Harland, R.M.2
  • 12
    • 33646562542 scopus 로고    scopus 로고
    • The logic of TGFbeta signaling
    • Massague J, Gomis RR,. The logic of TGFbeta signaling. FEBS Lett. 2006; 580 (12): 2811-2820.
    • (2006) FEBS Lett. , vol.580 , Issue.12 , pp. 2811-2820
    • Massague, J.1    Gomis, R.R.2
  • 13
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J,. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 2003; 113 (6): 685-700.
    • (2003) Cell. , vol.113 , Issue.6 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 14
    • 67649524640 scopus 로고    scopus 로고
    • Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (formaldehyde assisted isolation of regulatory elements)
    • Giresi PG, Lieb JD,. Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (formaldehyde assisted isolation of regulatory elements). Methods. 2009; 48 (3): 233-239.
    • (2009) Methods. , vol.48 , Issue.3 , pp. 233-239
    • Giresi, P.G.1    Lieb, J.D.2
  • 15
    • 79959531020 scopus 로고    scopus 로고
    • Regulation of RANKL-induced osteoclastogenesis by TGF-beta through molecular interaction between Smad3 and Traf6
    • Yasui T, Kadono Y, Nakamura M, et al. Regulation of RANKL-induced osteoclastogenesis by TGF-beta through molecular interaction between Smad3 and Traf6. J Bone Miner Res. 2011; 26 (7): 1447-1456.
    • (2011) J Bone Miner Res. , vol.26 , Issue.7 , pp. 1447-1456
    • Yasui, T.1    Kadono, Y.2    Nakamura, M.3
  • 16
    • 33749057086 scopus 로고    scopus 로고
    • Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role
    • Sasaki T, Kojima H, Kishimoto R, Ikeda A, Kunimoto H, Nakajima K,. Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role. Mol Cell. 2006; 24 (1): 63-75.
    • (2006) Mol Cell. , vol.24 , Issue.1 , pp. 63-75
    • Sasaki, T.1    Kojima, H.2    Kishimoto, R.3    Ikeda, A.4    Kunimoto, H.5    Nakajima, K.6
  • 17
    • 0037174944 scopus 로고    scopus 로고
    • Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator
    • Ishida N, Hayashi K, Hoshijima M, et al. Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator. J Biol Chem. 2002; 277 (43): 41147-41156.
    • (2002) J Biol Chem. , vol.277 , Issue.43 , pp. 41147-41156
    • Ishida, N.1    Hayashi, K.2    Hoshijima, M.3
  • 18
    • 18744366041 scopus 로고    scopus 로고
    • Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
    • Takayanagi H, Kim S, Koga T, et al. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell. 2002; 3 (6): 889-901.
    • (2002) Dev Cell. , vol.3 , Issue.6 , pp. 889-901
    • Takayanagi, H.1    Kim, S.2    Koga, T.3
  • 19
    • 0030933226 scopus 로고    scopus 로고
    • Osteopetrosis in mice lacking haematopoietic transcription factor PU
    • Tondravi MM, McKercher SR, Anderson K, et al. Osteopetrosis in mice lacking haematopoietic transcription factor PU. 1. Nature. 1997; 386 (6620): 81-84.
    • (1997) 1. Nature. , vol.386 , Issue.6620 , pp. 81-84
    • Tondravi, M.M.1    McKercher, S.R.2    Anderson, K.3
  • 20
    • 0036486771 scopus 로고    scopus 로고
    • The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts
    • Mansky KC, Marfatia K, Purdom GH, Luchin A, Hume DA, Ostrowski MC,. The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts. J Leukoc Biol. 2002; 71 (2): 295-303.
    • (2002) J Leukoc Biol. , vol.71 , Issue.2 , pp. 295-303
    • Mansky, K.C.1    Marfatia, K.2    Purdom, G.H.3    Luchin, A.4    Hume, D.A.5    Ostrowski, M.C.6
  • 21
    • 34447508339 scopus 로고    scopus 로고
    • MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation
    • Sharma SM, Bronisz A, Hu R, et al. MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. J Biol Chem. 2007; 282 (21): 15921-15929.
    • (2007) J Biol Chem. , vol.282 , Issue.21 , pp. 15921-15929
    • Sharma, S.M.1    Bronisz, A.2    Hu, R.3
  • 22
    • 5444225805 scopus 로고    scopus 로고
    • Elongation by RNA polymerase II: The short and long of it
    • Sims RJ, 3rd, Belotserkovskaya R, Reinberg D,. Elongation by RNA polymerase II: the short and long of it. Genes Dev. 2004; 18 (20): 2437-2468.
    • (2004) Genes Dev. , vol.18 , Issue.20 , pp. 2437-2468
    • Sims, R.J.1    Belotserkovskaya, R.2    Reinberg, D.3
  • 23
    • 41349094797 scopus 로고    scopus 로고
    • Transcription regulation through promoter-proximal pausing of RNA polymerase II
    • Core LJ, Lis JT,. Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science. 2008; 319 (5871): 1791-1792.
    • (2008) Science. , vol.319 , Issue.5871 , pp. 1791-1792
    • Core, L.J.1    Lis, J.T.2
  • 24
    • 0032191407 scopus 로고    scopus 로고
    • Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene
    • Hua X, Liu X, Ansari DO, Lodish HF,. Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene. Genes Dev. 1998; 12 (19): 3084-3095.
    • (1998) Genes Dev. , vol.12 , Issue.19 , pp. 3084-3095
    • Hua, X.1    Liu, X.2    Ansari, D.O.3    Lodish, H.F.4
  • 25
    • 0032110707 scopus 로고    scopus 로고
    • Characterization of human FAST-1, a TGF beta and activin signal transducer
    • Zhou S, Zawel L, Lengauer C, Kinzler KW, Vogelstein B,. Characterization of human FAST-1, a TGF beta and activin signal transducer. Mol Cell. 1998; 2 (1): 121-127.
    • (1998) Mol Cell. , vol.2 , Issue.1 , pp. 121-127
    • Zhou, S.1    Zawel, L.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 26
    • 0039844411 scopus 로고    scopus 로고
    • Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter
    • Hanai J, Chen LF, Kanno T, et al. Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter. J Biol Chem. 1999; 274 (44): 31577-31582.
    • (1999) J Biol Chem. , vol.274 , Issue.44 , pp. 31577-31582
    • Hanai, J.1    Chen, L.F.2    Kanno, T.3
  • 27
    • 0035971432 scopus 로고    scopus 로고
    • AP-1 in mouse development and tumorigenesis
    • Jochum W, Passegue E, Wagner EF,. AP-1 in mouse development and tumorigenesis. Oncogene. 2001; 20 (19): 2401-2412.
    • (2001) Oncogene. , vol.20 , Issue.19 , pp. 2401-2412
    • Jochum, W.1    Passegue, E.2    Wagner, E.F.3
  • 28
    • 0026486816 scopus 로고
    • Pleiotropic effects of a null mutation in the c-fos proto-oncogene
    • Johnson RS, Spiegelman BM, Papaioannou V,. Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell. 1992; 71 (4): 577-586.
    • (1992) Cell. , vol.71 , Issue.4 , pp. 577-586
    • Johnson, R.S.1    Spiegelman, B.M.2    Papaioannou, V.3
  • 30
    • 0033621698 scopus 로고    scopus 로고
    • Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation
    • Matsuo K, Owens JM, Tonko M, Elliott C, Chambers TJ, Wagner EF,. Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation. Nat Genet. 2000; 24 (2): 184-187.
    • (2000) Nat Genet. , vol.24 , Issue.2 , pp. 184-187
    • Matsuo, K.1    Owens, J.M.2    Tonko, M.3    Elliott, C.4    Chambers, T.J.5    Wagner, E.F.6
  • 31
    • 2942731511 scopus 로고    scopus 로고
    • Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos
    • Matsuo K, Galson DL, Zhao C, et al. Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. J Biol Chem. 2004; 279 (25): 26475-26480.
    • (2004) J Biol Chem. , vol.279 , Issue.25 , pp. 26475-26480
    • Matsuo, K.1    Galson, D.L.2    Zhao, C.3
  • 32
    • 0032572723 scopus 로고    scopus 로고
    • Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription
    • Zhang Y, Feng XH, Derynck R,. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature. 1998; 394 (6696): 909-913.
    • (1998) Nature. , vol.394 , Issue.6696 , pp. 909-913
    • Zhang, Y.1    Feng, X.H.2    Derynck, R.3
  • 33
    • 0037020178 scopus 로고    scopus 로고
    • Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene
    • Norwitz ER,., Xu S, Xu J, et al. Direct binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene. J Biol Chem. 2002; 277 (40): 37469-37478.
    • (2002) J Biol Chem , vol.277 , Issue.40 , pp. 37469-37478
    • Norwitz, E.R.1    Xu, S.2    Xu, J.3
  • 34
    • 0030697971 scopus 로고    scopus 로고
    • Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein
    • Yingling JM, Datto MB, Wong C, Frederick JP, Liberati NT, Wang XF,. Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein. Mol Cell Biol. 1997; 17 (12): 7019-7028.
    • (1997) Mol Cell Biol. , vol.17 , Issue.12 , pp. 7019-7028
    • Yingling, J.M.1    Datto, M.B.2    Wong, C.3    Frederick, J.P.4    Liberati, N.T.5    Wang, X.F.6
  • 35
    • 84881236485 scopus 로고    scopus 로고
    • Specific interactions between Smad proteins and AP-1 components determine TGFbeta-induced breast cancer cell invasion
    • Sundqvist A, Zieba A, Vasilaki E, et al. Specific interactions between Smad proteins and AP-1 components determine TGFbeta-induced breast cancer cell invasion. Oncogene. 2013; 32 (31): 3606-3615.
    • (2013) Oncogene. , vol.32 , Issue.31 , pp. 3606-3615
    • Sundqvist, A.1    Zieba, A.2    Vasilaki, E.3
  • 36
    • 79959911826 scopus 로고    scopus 로고
    • Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding
    • Biddie SC, John S, Sabo PJ, et al. Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding. Mol Cell. 2011; 43 (1): 145-155.
    • (2011) Mol Cell. , vol.43 , Issue.1 , pp. 145-155
    • Biddie, S.C.1    John, S.2    Sabo, P.J.3
  • 37
    • 80053539409 scopus 로고    scopus 로고
    • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
    • Song L, Zhang Z, Grasfeder LL, et al. Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. Genome Res. 2011; 21 (10): 1757-1767.
    • (2011) Genome Res. , vol.21 , Issue.10 , pp. 1757-1767
    • Song, L.1    Zhang, Z.2    Grasfeder, L.L.3


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