Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2-containing membranes

Proteins: Structure, Function and Bioinformatics

Volumn 83, Issue 5, 2015, Pages 952-969

  Khelashvili, George ^a   Doktorova, Milka ^a,b   Sahai, Michelle A ^a   Johner, Niklaus ^c   Shi, Lei ^a   Weinstein, Harel ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Amphetamine; Efflux; Electrostatics; Molecular dynamics; Neurotransmitter transporter; Phosphorylation; Signaling; Sodium symporter

Indexed keywords

AMINO ACID; DOPAMINE TRANSPORTER; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLSERINE; PLECTASIN; LIPID BILAYER;

AB INITIO CALCULATION; ARTICLE; BETA SHEET; CLUSTER ANALYSIS; COMPUTER MODEL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DENSITY; DISULFIDE BOND; HUMAN; HYDROPHOBICITY; LIPID ANALYSIS; LIPID BILAYER; LIPID COMPOSITION; LIPID MEMBRANE; MOLECULAR DYNAMICS; PREDICTION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LIPID INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; STATIC ELECTRICITY; STEADY STATE; CELL MEMBRANE; CHEMICAL PHENOMENA; CHEMISTRY; PROTEIN TERTIARY STRUCTURE;

CELL MEMBRANE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHATIDYLSERINES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84927698227     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24792     Document Type: Article

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