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Volumn 288, Issue 1, 2013, Pages 20-32

Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE BINDING; CONFORMATIONAL EQUILIBRIUM; DOPAMINE TRANSPORTERS; IN-VITRO; N-TERMINALS; PEPTIDE FRAGMENTS; PHOSPHOPEPTIDES; POTENTIAL SITES; PROTEIN KINASE; PROTEIN KINASE A; PROTEIN KINASE C; PURIFIED PROTEIN; SITE DIRECTED MUTAGENESIS;

EID: 84872069593     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.407874     Document Type: Article
Times cited : (46)

References (64)
  • 1
    • 33646649339 scopus 로고    scopus 로고
    • Regulation of monoamine transporters: Influence of psychostimulants and therapeutic antidepressants
    • Jayanthi, L. D., and Ramamoorthy, S. (2005) Regulation of monoamine transporters: influence of psychostimulants and therapeutic antidepressants. AAPS J. 7, E728-E738
    • (2005) AAPS J. , vol.7
    • Jayanthi, L.D.1    Ramamoorthy, S.2
  • 2
    • 0027446493 scopus 로고
    • Neurotransmitter transporters. Recent progress
    • Amara, S. G., and Kuhar, M. J. (1993) Neurotransmitter transporters. Recent progress. Annu. Rev. Neurosci. 16, 73-93
    • (1993) Annu. Rev. Neurosci. , vol.16 , pp. 73-93
    • Amara, S.G.1    Kuhar, M.J.2
  • 3
    • 73949083478 scopus 로고    scopus 로고
    • The rocking bundle. A mechanism for ion-coupled solute flux by symmetrical transporters
    • Forrest, L. R., and Rudnick, G. (2009) The rocking bundle. A mechanism for ion-coupled solute flux by symmetrical transporters. Physiology 24, 377-386
    • (2009) Physiology , vol.24 , pp. 377-386
    • Forrest, L.R.1    Rudnick, G.2
  • 4
    • 40849134173 scopus 로고    scopus 로고
    • Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors
    • DOI 10.1124/mol.107.039800
    • Loland, C. J., Desai, R. I., Zou, M. F., Cao, J., Grundt, P., Gerstbrein, K., Sitte, H. H., Newman, A. H., Katz, J. L., and Gether, U. (2008) Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors. Mol. Pharmacol. 73, 813-823 (Pubitemid 351397886)
    • (2008) Molecular Pharmacology , vol.73 , Issue.3 , pp. 813-823
    • Loland, C.J.1    Desai, R.I.2    Zou, M.-F.3    Cao, J.4    Grundt, P.5    Gerstbrein, K.6    Sitte, H.H.7    Newman, A.H.8    Katz, J.L.9    Gether, U.10
  • 8
    • 66149087730 scopus 로고    scopus 로고
    • A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters
    • Robertson, S. D., Matthies, H. J., and Galli, A. (2009) A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters. Mol. Neurobiol. 39, 73-80
    • (2009) Mol. Neurobiol. , vol.39 , pp. 73-80
    • Robertson, S.D.1    Matthies, H.J.2    Galli, A.3
  • 9
    • 0242660419 scopus 로고    scopus 로고
    • The effect of phosphorylation on amphetamine-mediated outward transport
    • Gnegy, M. E. (2003) The effect of phosphorylation on amphetamine-mediated outward transport. Eur. J. Pharmacol. 479, 83-91
    • (2003) Eur. J. Pharmacol. , vol.479 , pp. 83-91
    • Gnegy, M.E.1
  • 10
    • 0031846705 scopus 로고    scopus 로고
    • Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter
    • Sitte, H. H., Huck, S., Reither, H., Boehm, S., Singer, E. A., and Pifl, C. (1998) Carrier-mediated release, transport rates, and charge transfer in- duced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter. J. Neurochem. 71, 1289-1297 (Pubitemid 28390284)
    • (1998) Journal of Neurochemistry , vol.71 , Issue.3 , pp. 1289-1297
    • Sitte, H.H.1    Huck, S.2    Reither, H.3    Boehm, S.4    Singer, E.A.5    Pifl, C.6
  • 11
    • 77956188433 scopus 로고    scopus 로고
    • Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression
    • Cervinski, M. A., Foster, J. D., and Vaughan, R. A. (2010) Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression. Neuroscience 170, 408-416
    • (2010) Neuroscience , vol.170 , pp. 408-416
    • Cervinski, M.A.1    Foster, J.D.2    Vaughan, R.A.3
  • 13
    • 52949117702 scopus 로고    scopus 로고
    • Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission
    • Carvelli, L., Blakely, R. D., and DeFelice, L. J. (2008) Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission. Proc. Natl. Acad. Sci. U.S.A. 105, 14192-14197
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 14192-14197
    • Carvelli, L.1    Blakely, R.D.2    DeFelice, L.J.3
  • 15
    • 79151476913 scopus 로고    scopus 로고
    • Regulation of monoamine transporters. Role of transporter phosphorylation
    • Ramamoorthy, S., Shippenberg, T. S., and Jayanthi, L. D. (2011) Regulation of monoamine transporters. Role of transporter phosphorylation. Pharmacol. Ther. 129, 220-238
    • (2011) Pharmacol. Ther. , vol.129 , pp. 220-238
    • Ramamoorthy, S.1    Shippenberg, T.S.2    Jayanthi, L.D.3
  • 17
    • 0242408679 scopus 로고    scopus 로고
    • Regulation of dopamine transporter function and plasma membrane expression by dopamine, amphetamine, and cocaine
    • DOI 10.1016/j.ejphar.2003.08.065
    • Kahlig, K. M., and Galli, A. (2003) Regulation of dopamine transporter function and plasma membrane expression by dopamine, amphetamine, and cocaine. Eur. J. Pharmacol. 479, 153-158 (Pubitemid 37377884)
    • (2003) European Journal of Pharmacology , vol.479 , Issue.1-3 , pp. 153-158
    • Kahlig, K.M.1    Galli, A.2
  • 18
    • 3042648050 scopus 로고    scopus 로고
    • Phosphorylation and regulation of psychostimulant-sensitive neurotransmitter transporters
    • Vaughan, R. A. (2004) Phosphorylation and regulation of psychostimulant-sensitive neurotransmitter transporters. J. Pharmacol. Exp. Ther. 310, 1-7
    • (2004) J. Pharmacol. Exp. Ther. , vol.310 , pp. 1-7
    • Vaughan, R.A.1
  • 19
    • 77949281313 scopus 로고    scopus 로고
    • Regulation of the dopamine transporter: Aspects relevant to psychostimulant drugs of abuse
    • Schmitt, K. C., and Reith, M. E. (2010) Regulation of the dopamine transporter: aspects relevant to psychostimulant drugs of abuse. Ann. N.Y. Acad. Sci. 1187, 316-340
    • (2010) Ann. N.Y. Acad. Sci. , vol.1187 , pp. 316-340
    • Schmitt, K.C.1    Reith, M.E.2
  • 20
    • 28844445514 scopus 로고    scopus 로고
    • Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms
    • DOI 10.1074/jbc.M501969200
    • Cervinski, M. A., Foster, J. D., and Vaughan, R. A. (2005) Psychoactive substrates stimulate dopamine transporter phosphorylation and downregulation by cocaine-sensitive and protein kinase C-dependent mechanisms. J. Biol. Chem. 280, 40442-40449 (Pubitemid 41780531)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.49 , pp. 40442-40449
    • Cervinski, M.A.1    Foster, J.D.2    Vaughan, R.A.3
  • 23
    • 0035007651 scopus 로고    scopus 로고
    • Protein kinase C-mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein
    • DOI 10.1046/j.1471-4159.2001.00284.x
    • Chang, M. Y., Lee, S. H., Kim, J. H., Lee, K. H., Kim, Y. S., Son, H., and Lee, Y. S. (2001) Protein kinase C-mediated functional regulation of dopamine transporter is not achieved by direct phosphorylation of the dopamine transporter protein. J. Neurochem. 77, 754-761 (Pubitemid 32471848)
    • (2001) Journal of Neurochemistry , vol.77 , Issue.3 , pp. 754-761
    • Chang, M.-Y.1    Lee, S.-H.2    Kim, J.-H.3    Lee, K.-H.4    Kim, Y.-S.5    Son, H.6    Lee, Y.-S.7
  • 24
    • 0037775994 scopus 로고    scopus 로고
    • N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization
    • DOI 10.1074/jbc.M205058200
    • Granas, C., Ferrer, J., Loland, C. J., Javitch, J. A., and Gether, U. (2003) N-terminal truncation of the dopamine transporter abolishes phorbol es-ter- and substance P receptor-stimulated phosphorylation without impairing transporter internalization. J. Biol. Chem. 278, 4990-5000 (Pubitemid 36801008)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.7 , pp. 4990-5000
    • Granas, C.1    Ferrer, J.2    Loland, C.J.3    Javitch, J.A.4    Gether, U.5
  • 26
    • 0030972751 scopus 로고    scopus 로고
    • Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
    • DOI 10.1074/jbc.272.24.15541
    • Vaughan, R. A., Huff, R. A., Uhl, G. R., and Kuhar, M. J. (1997) Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes. J. Biol. Chem. 272, 15541-15546 (Pubitemid 27255584)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.24 , pp. 15541-15546
    • Vaughan, R.A.1    Huff, R.A.2    Uhl, G.R.3    Kuhar, M.J.4
  • 27
    • 0037067690 scopus 로고    scopus 로고
    • Dopamine transporters are phosphorylated on N-terminal serines in rat striatum
    • DOI 10.1074/jbc.M200294200
    • Foster, J. D., Pananusorn, B., and Vaughan, R. A. (2002) Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. J. Biol. Chem. 277, 25178-25186 (Pubitemid 34951824)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.28 , pp. 25178-25186
    • Foster, J.D.1    Pananusorn, B.2    Vaughan, R.A.3
  • 28
    • 61449170264 scopus 로고    scopus 로고
    • Proline-directed phosphorylation of the dopamine transporter N-terminal domain
    • Gorentla, B. K., Moritz, A. E., Foster, J. D., and Vaughan, R. A. (2009) Proline-directed phosphorylation of the dopamine transporter N-terminal domain. Biochemistry 48, 1067-1076
    • (2009) Biochemistry , vol.48 , pp. 1067-1076
    • Gorentla, B.K.1    Moritz, A.E.2    Foster, J.D.3    Vaughan, R.A.4
  • 31
    • 1342265784 scopus 로고    scopus 로고
    • Uptake Inhibitors but not Substrates Induce Protease Resistance in Extracellular Loop Two of the Dopamine Transporter
    • DOI 10.1124/mol.65.3.692
    • Gaffaney, J. D., and Vaughan, R. A. (2004) Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Mol. Pharmacol. 65, 692-701 (Pubitemid 38264037)
    • (2004) Molecular Pharmacology , vol.65 , Issue.3 , pp. 692-701
    • Gaffaney, J.D.1    Vaughan, R.A.2
  • 33
    • 0029816108 scopus 로고    scopus 로고
    • Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis
    • DOI 10.1074/jbc.271.35.21672
    • Vaughan, R. A., and Kuhar, M. J. (1996) Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis. J. Biol. Chem. 271, 21672-21680 (Pubitemid 26293039)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.35 , pp. 21672-21680
    • Vaughan, R.A.1    Kuhar, M.J.2
  • 34
    • 0025998840 scopus 로고
    • Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
    • Boyle, W. J., van der Geer, P., and Hunter, T. (1991) Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol. 201, 110-149
    • (1991) Methods Enzymol. , vol.201 , pp. 110-149
    • Boyle, W.J.1    Van Der Geer, P.2    Hunter, T.3
  • 36
    • 0035830829 scopus 로고    scopus 로고
    • Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells
    • Schmid, J. A., Scholze, P., Kudlacek, O., Freissmuth, M., Singer, E. A., and Sitte, H. H. (2001) Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells. J. Biol. Chem. 276, 3805-3810
    • (2001) J. Biol. Chem. , vol.276 , pp. 3805-3810
    • Schmid, J.A.1    Scholze, P.2    Kudlacek, O.3    Freissmuth, M.4    Singer, E.A.5    Sitte, H.H.6
  • 37
    • 38049132028 scopus 로고    scopus 로고
    • Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression
    • Yang, J. W., Vacher, H., Park, K. S., Clark, E., and Trimmer, J. S. (2007) Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression. Proc. Natl. Acad. Sci. U.S.A. 104, 20055-20060
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 20055-20060
    • Yang, J.W.1    Vacher, H.2    Park, K.S.3    Clark, E.4    Trimmer, J.S.5
  • 38
    • 70349977109 scopus 로고    scopus 로고
    • Hippocampal protein levels related to spatial memory are different in the Barnes maze and in the multiple T-maze
    • Zheng, J. F., Patil, S. S., Chen, W. Q., An, W., He, J. Q., Höger, H., and Lubec, G. (2009) Hippocampal protein levels related to spatial memory are different in the Barnes maze and in the multiple T-maze. J. Proteome Res. 8, 4479-4486
    • (2009) J. Proteome Res. , vol.8 , pp. 4479-4486
    • Zheng, J.F.1    Patil, S.S.2    Chen, W.Q.3    An, W.4    He, J.Q.5    Höger, H.6    Lubec, G.7
  • 39
    • 43049179873 scopus 로고    scopus 로고
    • Phosphopeptide mapping and identification of phosphorylation sites
    • Chapter 13, Unit 13.9
    • Meisenhelder, J., Hunter, T., and van der Geer, P. (2001) Phosphopeptide mapping and identification of phosphorylation sites. Curr. Protoc. Protein Sci. Chapter 13, Unit 13.9
    • (2001) Curr. Protoc. Protein Sci.
    • Meisenhelder, J.1    Hunter, T.2    Van Der Geer, P.3
  • 40
    • 0028169067 scopus 로고
    • Phorbol esters alter functions of the expressed dopamine transporter
    • Kitayama, S., Dohi, T., and Uhl, G. R. (1994) Phorbol esters alter functions of the expressed dopamine transporter. Eur. J. Pharmacol. 268, 115-119
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 115-119
    • Kitayama, S.1    Dohi, T.2    Uhl, G.R.3
  • 41
    • 0030936222 scopus 로고    scopus 로고
    • Regulation of the functional activity of the human dopamine transporter by protein kinase C
    • DOI 10.1016/S0006-2952(96)00898-2, PII S0006295296008982
    • Zhang, L., Coffey, L. L., and Reith, M. E. (1997) Regulation of the functional activity of the human dopamine transporter by protein kinase C. Biochem. Pharmacol. 53, 677-688 (Pubitemid 27148245)
    • (1997) Biochemical Pharmacology , vol.53 , Issue.5 , pp. 677-688
    • Zhang, L.1    Coffey, L.L.2    Reith, M.E.A.3
  • 42
    • 0032535582 scopus 로고    scopus 로고
    • Cocaine acts as an apparent competitive inhibitor at the outward-facing conformation of the human norepinephrine transporter: Kinetic analysis of inward and outward transport
    • Chen, N., and Justice, J. B., Jr. (1998) Cocaine acts as an apparent competitive inhibitor at the outward-facing conformation of the human norepinephrine transporter. Kinetic analysis of inward and outward transport. J. Neurosci. 18, 10257-10268 (Pubitemid 29016545)
    • (1998) Journal of Neuroscience , vol.18 , Issue.24 , pp. 10257-10268
    • Chen, N.1    Justice Jr., J.B.2
  • 43
    • 0037022356 scopus 로고    scopus 로고
    • 2+ switch in the dopamine transporter. Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle
    • 2+ switch in the dopamine transporter. Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle. Proc. Natl. Acad. Sci. U.S.A. 99, 1683-1688
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 1683-1688
    • Loland, C.J.1    Norregaard, L.2    Litman, T.3    Gether, U.4
  • 44
    • 77957791961 scopus 로고    scopus 로고
    • Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding
    • Hong, W. C., and Amara, S. G. (2010) Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J. Biol. Chem. 285, 32616-32626
    • (2010) J. Biol. Chem. , vol.285 , pp. 32616-32626
    • Hong, W.C.1    Amara, S.G.2
  • 45
    • 0027455744 scopus 로고
    • Zinc modulation of drug binding, cocaine affinity states, and dopamine uptake on the dopamine uptake complex
    • Richfield, E. K. (1993) Zinc modulation of drug binding, cocaine affinity states, and dopamine uptake on the dopamine uptake complex. Mol. Pharmacol. 43, 100-108
    • (1993) Mol. Pharmacol. , vol.43 , pp. 100-108
    • Richfield, E.K.1
  • 46
    • 0032480011 scopus 로고    scopus 로고
    • Delineation of an endogenous zinc-binding site in the human dopamine transporter
    • DOI 10.1093/emboj/17.15.4266
    • Norregaard, L., Frederiksen, D., Nielsen, E. O., and Gether, U. (1998) Delineation of an endogenous zinc-binding site in the human dopamine transporter. EMBO J. 17, 4266-4273 (Pubitemid 28362617)
    • (1998) EMBO Journal , vol.17 , Issue.15 , pp. 4266-4273
    • Norregaard, L.1    Frederiksen, D.2    Nielsen, E.O.3    Gether, U.4
  • 47
    • 72849113289 scopus 로고    scopus 로고
    • --coupled neurotransmitter transporters-why amphetamines take two to tango
    • --coupled neurotransmitter transporters-why amphetamines take two to tango. J. Neurochem. 112, 340-355
    • (2010) J. Neurochem. , vol.112 , pp. 340-355
    • Sitte, H.H.1    Freissmuth, M.2
  • 51
    • 79951978579 scopus 로고    scopus 로고
    • Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters
    • Guptaroy, B., Fraser, R., Desai, A., Zhang, M., and Gnegy, M. E. (2011) Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters. Mol. Pharmacol. 79, 520-532
    • (2011) Mol. Pharmacol. , vol.79 , pp. 520-532
    • Guptaroy, B.1    Fraser, R.2    Desai, A.3    Zhang, M.4    Gnegy, M.E.5
  • 53
    • 2542420799 scopus 로고    scopus 로고
    • Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine
    • DOI 10.1111/j.1471-4159.2004.02386.x
    • Chen, N., Zhen, J., and Reith, M. E. (2004) Mutation of Trp-84 and Asp-313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine. J. Neurochem. 89, 853-864 (Pubitemid 38684733)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.4 , pp. 853-864
    • Chen, N.1    Zhen, J.2    Reith, M.E.A.3
  • 54
    • 1242317021 scopus 로고    scopus 로고
    • Aspartate 345 of the Dopamine Transporter Is Critical for Conformational Changes in Substrate Translocation and Cocaine Binding
    • DOI 10.1074/jbc.M306294200
    • Chen, N., Rickey, J., Berfield, J. L., and Reith, M. E. (2004) Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding. J. Biol. Chem. 279, 5508-5519 (Pubitemid 38220576)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 5508-5519
    • Chen, N.1    Rickey, J.2    Berfield, J.L.3    Reith, M.E.A.4
  • 55
    • 0031035072 scopus 로고    scopus 로고
    • Phorbol esters increase dopamine transporter phosphorylation and decrease transport V(max)
    • Huff, R. A., Vaughan, R. A., Kuhar, M. J., and Uhl, G. R. (1997) Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax. J. Neurochem. 68, 225-232 (Pubitemid 26427311)
    • (1997) Journal of Neurochemistry , vol.68 , Issue.1 , pp. 225-232
    • Huff, R.A.1    Vaughan, R.A.2    Kuhar, M.J.3    Uhl, G.R.4
  • 56
    • 43549127315 scopus 로고    scopus 로고
    • Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol
    • DOI 10.1111/j.1471-4159.2008.05262.x
    • Foster, J. D., Adkins, S. D., Lever, J. R., and Vaughan, R. A. (2008) Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol. J. Neurochem. 105, 1683-1699 (Pubitemid 351678491)
    • (2008) Journal of Neurochemistry , vol.105 , Issue.5 , pp. 1683-1699
    • Foster, J.D.1    Adkins, S.D.2    Lever, J.R.3    Vaughan, R.A.4
  • 57
    • 47749083479 scopus 로고    scopus 로고
    • An intracellular interaction network regulates conformational transitions in the dopamine transporter
    • Kniazeff, J., Shi, L., Loland, C. J., Javitch, J. A., Weinstein, H., and Gether, U. (2008) An intracellular interaction network regulates conformational transitions in the dopamine transporter. J. Biol. Chem. 283, 17691-17701
    • (2008) J. Biol. Chem. , vol.283 , pp. 17691-17701
    • Kniazeff, J.1    Shi, L.2    Loland, C.J.3    Javitch, J.A.4    Weinstein, H.5    Gether, U.6
  • 58
    • 84856225222 scopus 로고    scopus 로고
    • X-ray structures of LeuT in substrate-free outward-open and apo inward-open states
    • Krishnamurthy, H., and Gouaux, E. (2012) X-ray structures of LeuT in substrate-free outward-open and apo inward-open states. Nature 481, 469-474
    • (2012) Nature , vol.481 , pp. 469-474
    • Krishnamurthy, H.1    Gouaux, E.2
  • 59
    • 3442895932 scopus 로고    scopus 로고
    • Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter
    • Lee, K. H., Kim, M. Y., Kim, D. H., and Lee, Y. S. (2004) Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter. Neurochem. Res. 29, 1405-1409
    • (2004) Neurochem. Res. , vol.29 , pp. 1405-1409
    • Lee, K.H.1    Kim, M.Y.2    Kim, D.H.3    Lee, Y.S.4
  • 60
    • 3042543911 scopus 로고    scopus 로고
    • The up-regulation of the striatal dopamine transporter's activity by cAMP is PKA-, CaMK II- and phosphatase-dependent
    • DOI 10.1016/j.neuint.2004.04.002, PII S0197018604000774
    • Page, G., Barc-Pain, S., Pontcharraud, R., Cante, A., Piriou, A., and Barrier, L. (2004) The up-regulation of the striatal dopamine transporter's activity by cAMP is PKA-, CaMK II-, and phosphatase-dependent. Neurochem. Int. 45, 627-632 (Pubitemid 38844883)
    • (2004) Neurochemistry International , vol.45 , Issue.5 , pp. 627-632
    • Page, G.1    Barc-Pain, S.2    Pontcharraud, R.3    Cante, A.4    Piriou, A.5    Barrier, L.6
  • 61
    • 0347064325 scopus 로고    scopus 로고
    • Repeated amphetamine treatment induces neurite outgrowth and enhanced amphetamine-stimulated dopamine release in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism
    • Park, Y. H., Kantor, L., Guptaroy, B., Zhang, M., Wang, K. K., and Gnegy, M. E. (2003) Repeated amphetamine treatment induces neurite outgrowth and enhanced amphetamine-stimulated dopamine release in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism. J. Neurochem. 87, 1546-1557 (Pubitemid 38020588)
    • (2003) Journal of Neurochemistry , vol.87 , Issue.6 , pp. 1546-1557
    • Park, Y.H.1    Kantor, L.2    Guptaroy, B.3    Zhang, M.4    Wang, K.K.W.5    Gnegy, M.E.6
  • 62
    • 0031855610 scopus 로고    scopus 로고
    • Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter
    • DOI 10.1002/(SICI)1098-2396(199809)30:1<79::AID-SYN10>3.0.CO;2-K
    • Pristupa, Z. B., McConkey, F., Liu, F., Man, H. Y., Lee, F. J., Wang, Y. T., and Niznik, H. B. (1998) Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter. Synapse 30, 79-87 (Pubitemid 28361186)
    • (1998) Synapse , vol.30 , Issue.1 , pp. 79-87
    • Pristupa, Z.B.1    McConkey, F.2    Liu, F.3    Man, H.Y.4    Lee, F.J.S.5    Wang, Y.T.6    Niznik, H.B.7
  • 63
    • 0032535497 scopus 로고    scopus 로고
    • Protein kinase A activity may kinetically up-regulate the striatal transporter for dopamine
    • Batchelor, M., and Schenk, J. O. (1998) Protein kinase A activity may kinetically up-regulate the striatal transporter for dopamine. J. Neurosci. 18, 10304-10309
    • (1998) J. Neurosci. , vol.18 , pp. 10304-10309
    • Batchelor, M.1    Schenk, J.O.2
  • 64
    • 15744403400 scopus 로고    scopus 로고
    • Regulation of amphetamine-stimulated dopamine efflux by protein kinase C β
    • DOI 10.1074/jbc.M413887200
    • Johnson, L. A., Guptaroy, B., Lund, D., Shamban, S., and Gnegy, M. E. (2005) Regulation of amphetamine-stimulated dopamine efflux by protein kinase Cβ. J. Biol. Chem. 280, 10914-10919 (Pubitemid 40418392)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.12 , pp. 10914-10919
    • Johnson, L.A.1    Guptaroy, B.2    Lund, D.3    Shamban, S.4    Gnegy, M.E.5


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