Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair

EMBO Journal

Volumn 34, Issue 8, 2015, Pages 1126-1142

  Gouge, Jérôme ^a,c   Rosario, Sandrine ^a   Romain, Félix ^a   Poitevin, Frédéric ^b   Béguin, Pierre ^a   Delarue, Marc ^a  

^a INSTITUT PASTEUR   (France)

^b CEA SACLAY   (France)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

DNA repair; DNA synapsis; micro homology base pair; non homologous end joining; X ray crystallography

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; DNA POLYMERASE; OLIGONUCLEOTIDE; PROTEIN POLX; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; DNA POLYMERASE MU;

3' UNTRANSLATED REGION; ARTICLE; BASE PAIRING; CRYSTAL STRUCTURE; DNA END JOINING REPAIR; DNA REPAIR; DNA STRUCTURE; DOUBLE STRANDED DNA BREAK; EUKARYOTE; GENETIC RECOMBINATION; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN FAMILY; SITE DIRECTED MUTAGENESIS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; EUKARYOTIC CELL; METABOLISM; MOUSE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN CONFORMATION; VDJ RECOMBINATION; X RAY CRYSTALLOGRAPHY;

EUKARYOTA; SYNAPSIS;

ANIMALS; BASE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA NUCLEOTIDYLEXOTRANSFERASE; DNA-DIRECTED DNA POLYMERASE; EUKARYOTIC CELLS; MICE; MODELS, MOLECULAR; PROTEIN CONFORMATION; V(D)J RECOMBINATION;

EID: 84927690488     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201489643     Document Type: Article

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