Sustained active site rigidity during synthesis by human DNA polymerase μ

Nature Structural and Molecular Biology

Volumn 21, Issue 3, 2014, Pages 253-260

  Moon, Andrea F ^a   Pryor, John M ^b   Ramsden, Dale A ^b   Kunkel, Thomas A ^a   Bebenek, Katarzyna ^a   Pedersen, Lars C ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPROTEIN; DNA POLYMERASE; DNA POLYMERASE MU; DOUBLE STRANDED DNA; NUCLEOTIDE; THYMIDINE TRIPHOSPHATE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DNA BINDING; DNA END JOINING REPAIR; DNA SYNTHESIS; DNA TEMPLATE; DOUBLE STRANDED DNA BREAK; ENTROPY; ENZYME ACTIVE SITE; HUMAN; HYDROGEN BOND; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; STATIC ELECTRICITY; WILD TYPE; X RAY CRYSTALLOGRAPHY;

CATALYSIS; CATALYTIC DOMAIN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; ELECTRONS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; NUCLEOTIDES; PROTEIN BINDING; SUBSTRATE SPECIFICITY;

EID: 84895890321     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2766     Document Type: Article

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