Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections

Expert Opinion on Investigational Drugs

Volumn 24, Issue 5, 2015, Pages 689-704

  Khan, Burhan A ^a   Yeh, Anthony J ^b   Cheung, Gordon Yc ^b   Otto, Michael ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Quorum sensing; Quorum sensing blockers; Staphylococcus aureus; Staphylococcus epidermidis

Indexed keywords

MONOCLONAL ANTIBODY; ANTIINFECTIVE AGENT; NEW DRUG;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; BACTERIAL GENOME; BACTERIAL VIRULENCE; CELL COMMUNICATION; DOWN REGULATION; EXPERIMENTAL THERAPY; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MORBIDITY; MORTALITY; NONHUMAN; QUORUM SENSING; REGULATOR GENE; REVIEW; STAPHYLOCOCCUS INFECTION; UPREGULATION; VIRUS PATHOGENESIS; VIRUS VIRULENCE; ANIMAL; DRUG DESIGN; DRUG EFFECTS; MICROBIOLOGY; PATHOGENICITY; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; DRUGS, INVESTIGATIONAL; HUMANS; QUORUM SENSING; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84927631961     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2015.1019062     Document Type: Review

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