N-Methyl and peptoid scans of an autoinducing peptide reveal new structural features required for inhibition and activation of AgrC quorum sensing receptors in Staphylococcus aureus

Chemical Communications

Volumn 50, Issue 23, 2014, Pages 3000-3003

  Tal Gan, Yftah ^a   Stacy, Danielle M ^a   Blackwell, Helen E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AUTOINDUCING PEPTIDE; MACROCYCLIC COMPOUND; MEMBRANE RECEPTOR; PEPTIDE; PEPTOID; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ACCESSORY GENE REGULATOR C; ARTICLE; BACTERIAL GENE; GENE ACTIVATION; NONHUMAN; QUORUM SENSING; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; HUMANS; METHYLATION; PEPTOIDS; PROTEIN KINASES; QUORUM SENSING; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84894500955     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c4cc00117f     Document Type: Article

References (18)

1. H. F. Chambers, F. R. DeLeo, Nat. Rev. Microbiol., 2009, 7, 629-641
2. E. A. George, T. W. Muir, ChemBioChem, 2007, 8, 847-855
3. J. R. Li, W. L. Wang, S. X. Xu, N. A. Magarvey, J. K. McCormick, Proc. Natl. Acad. Sci. U. S. A., 2011, 108, 3360-3365
4. G. Ji, R. Beavis, R. P. Novick, Science, 1997, 276, 2027-2030
5. R. P. Novick, E. Geisinger, Annu. Rev. Genet., 2008, 42, 541-564
6. P. McDowell, Z. Affas, C. Reynolds, M. T. Holden, S. J. Wood, S. Saint, A. Cockayne, P. J. Hill, C. E. Dodd, B. W. Bycroft, W. C. Chan, P. Williams, Mol. Microbiol., 2001, 41, 503-512
7. S. Jarraud, G. J. Lyon, A. M. Figueiredo, L. Gerard, F. Vandenesch, J. Etienne, T. W. Muir, R. P. Novick, J. Bacteriol., 2000, 182, 6517-6522
8. M. Thoendel, J. S. Kavanaugh, C. E. Flack, A. R. Horswill, Chem. Rev., 2011, 111, 117-151
9. C. P. Gordon, P. Williams, W. C. Chan, J. Med. Chem., 2013, 56, 1389-1404
10. N. Amara, B. P. Krom, G. F. Kaufmann, M. M. Meijler, Chem. Rev., 2011, 111, 195-208
11. Y. Tal-Gan, D. M. Stacy, M. K. Foegen, D. W. Koenig, H. E. Blackwell, J. Am. Chem. Soc., 2013, 135, 7869-7882
12. V. Fleming, E. Feil, A. K. Sewell, N. Day, A. Buckling, R. C. Massey, J. Bacteriol., 2006, 188, 7686-7688
13. G. J. Lyon, J. S. Wright, T. W. Muir, R. P. Novick, Biochemistry, 2002, 41, 10095-10104
14. Y. Tal-Gan, M. Ivancic, G. Cornilescu, C. C. Cornilescu, H. E. Blackwell, J. Am. Chem. Soc., 2013, 135, 18436-18444
15. S. A. Fowler, D. M. Stacy, H. E. Blackwell, Org. Lett., 2008, 10, 2329-2332
16. E. A. George, R. P. Novick, T. W. Muir, J. Am. Chem. Soc., 2008, 130, 4914-4924
17. R. N. Kirchdoerfer, A. L. Garner, C. E. Flack, J. M. Mee, A. R. Horswill, K. D. Janda, G. F. Kaufmann, I. A. Wilson, J. Biol. Chem., 2011, 286, 17351-17358
18. G. J. Lyon, P. Mayville, T. W. Muir, R. P. Novick, Proc. Natl. Acad. Sci. U. S. A., 2000, 97, 13330-13335