Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 15, 2003, Pages 2449-2453

  Scott, R John ^a   Lian, Lu Yun ^b   Muharram, S Hanna ^a   Cockayne, Alan ^a   Wood, Stewart J ^a   Bycroft, Barrie W ^a   Williams, Paul ^a   Chan, Weng C ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGR PROTEIN, STAPHYLOCOCCUS AUREUS; BACTERIAL PROTEIN; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; GAMMA BUTYROLACTONE; LACTONE; N (3 OXOHEXANOYL) 3 AMINODIHYDRO 2(3H) FURANONE; N-(3-OXOHEXANOYL)-3-AMINODIHYDRO-2(3H)-FURANONE; PEPTIDE; PROTEIN INHIBITOR; REGULATOR PROTEIN; THIOLACTONE; TRANSACTIVATOR PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; BINDING KINETICS; CONTROLLED STUDY; CYCLIZATION; DOSE RESPONSE; DRUG DESIGN; DRUG EFFECT; DRUG SYNTHESIS; GENETICS; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PHARMACOPHORE; PHYSIOLOGY; PROTON NUCLEAR MAGNETIC RESONANCE; REPORTER GENE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SIGNAL TRANSDUCTION; SOLID; STAPHYLOCOCCUS; STRUCTURE ACTIVITY RELATION;

EID: 0037633762     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00497-9     Document Type: Article

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