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Volumn 33, Issue , 2015, Pages 29-48

HLA-B27

Author keywords

Ankylosing spondylitis; Antigen presentation; Arthritogenic peptide; Homodimer; Spondyloarthritis

Indexed keywords

AMINOPEPTIDASE; AMYLOID; CD8 ANTIGEN; ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1; HLA B27 ANTIGEN; PEPTIDASE; UNCLASSIFIED DRUG;

EID: 84927631241     PISSN: 07320582     EISSN: 15453278     Source Type: Book Series    
DOI: 10.1146/annurev-immunol-032414-112110     Document Type: Review
Times cited : (207)

References (109)
  • 1
    • 0015899336 scopus 로고
    • Cytotoxic thymus-derived lymphocytes in cerebrospinal fluid of mice with lymphocytic choriomeningitis
    • Zinkernagel RM, Doherty PC. 1973. Cytotoxic thymus-derived lymphocytes in cerebrospinal fluid of mice with lymphocytic choriomeningitis. J. Exp. Med. 138(5):1266-69
    • (1973) J. Exp. Med. , vol.138 , Issue.5 , pp. 1266-1269
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 2
    • 0016345568 scopus 로고
    • Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system
    • Zinkernagel RM, Doherty PC. 1974. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 248(5450):701-2
    • (1974) Nature , vol.248 , Issue.5450 , pp. 701-702
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 3
    • 0022483534 scopus 로고
    • The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides
    • Townsend AR, Rothbard J, Gotch FM, Bahadur G, Wraith D, McMichael AJ. 1986. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 44(6):959-68
    • (1986) Cell , vol.44 , Issue.6 , pp. 959-968
    • Townsend, A.R.1    Rothbard, J.2    Gotch, F.M.3    Bahadur, G.4    Wraith, D.5    McMichael, A.J.6
  • 4
    • 0023685463 scopus 로고
    • HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides
    • Nixon DF, Townsend AR, Elvin JG, Rizza CR, Gallwey J, McMichael AJ. 1988. HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides. Nature 336(6198):484-87
    • (1988) Nature , vol.336 , Issue.6198 , pp. 484-487
    • Nixon, D.F.1    Townsend, A.R.2    Elvin, J.G.3    Rizza, C.R.4    Gallwey, J.5    McMichael, A.J.6
  • 5
    • 0025305927 scopus 로고
    • Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27
    • Huet S, Nixon DF, Rothbard JB, Townsend A, Ellis SA, McMichael AJ. 1990. Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27. Int. Immunol. 2(4):311-16
    • (1990) Int. Immunol. , vol.2 , Issue.4 , pp. 311-316
    • Huet, S.1    Nixon, D.F.2    Rothbard, J.B.3    Townsend, A.4    Ellis, S.A.5    McMichael, A.J.6
  • 6
    • 0025813156 scopus 로고
    • The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation
    • Madden DR, Gorga JC, Strominger JL,Wiley DC. 1991. The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation. Nature 353(6342):321-25
    • (1991) Nature , vol.353 , Issue.6342 , pp. 321-325
    • Madden, D.R.1    Gorga, J.C.2    Strominger, J.L.3    Wiley, D.C.4
  • 7
    • 0026794581 scopus 로고
    • The three-dimensional structure of HLA-B27 at 2. 1A resolution suggests a general mechanism for tight peptide binding to MHC
    • MaddenDR, Gorga JC, Strominger JL,WileyDC. 1992. The three-dimensional structure of HLA-B27 at 2. 1A resolution suggests a general mechanism for tight peptide binding to MHC. Cell 70(6):1035. 48
    • (1992) Cell , vol.70 , Issue.6 , pp. 1035-1048
    • Madden, D.R.1    Gorga, J.C.2    Strominger, J.L.3    Wiley, D.C.4
  • 9
    • 0027261331 scopus 로고
    • Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide
    • Brooks JM, Murray RJ, Thomas WA, Kurilla MG, Rickinson AB. 1993. Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide. J. Exp. Med. 178(3):879. 87
    • (1993) J. Exp. Med. , vol.178 , Issue.3 , pp. 879-887
    • Brooks, J.M.1    Murray, R.J.2    Thomas, W.A.3    Kurilla, M.G.4    Rickinson, A.B.5
  • 10
    • 0029970715 scopus 로고    scopus 로고
    • Extended repertoire of permissible peptide ligands for HLA-B. 2702
    • Raghavan M, Lebrón JA, Johnson JL, Bjorkman PJ. 1996. Extended repertoire of permissible peptide ligands for HLA-B. 2702. Protein Sci. 5(10):2080.
    • (1996) Protein Sci. , vol.5 , Issue.10 , pp. 2080
    • Raghavan, M.1    Lebrón, J.A.2    Johnson, J.L.3    Bjorkman, P.J.4
  • 12
    • 0032076171 scopus 로고    scopus 로고
    • HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class i peptide loading
    • Peh CA, Burrows SR, Barnden M, Khanna R, Cresswell P, et al. 1998. HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading. Immunity 8(5):531. 42
    • (1998) Immunity , vol.8 , Issue.5 , pp. 531-542
    • Peh, C.A.1    Burrows, S.R.2    Barnden, M.3    Khanna, R.4    Cresswell, P.5
  • 13
    • 16944366524 scopus 로고    scopus 로고
    • Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS
    • Goulder PJ, Phillips RE, Colbert RA, McAdam S, OggG, et al. 1997. Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS. Nat. Med. 3(2):212. 17
    • (1997) Nat. Med. , vol.3 , Issue.2 , pp. 212-217
    • Goulder, P.J.1    Phillips, R.E.2    Colbert, R.A.3    McAdam, S.4    Ogg, G.5
  • 15
    • 61749103383 scopus 로고    scopus 로고
    • Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response
    • Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, et al. 2009. Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response. J. Clin. Investig. 119(2):376. 86
    • (2009) J. Clin. Investig. , vol.119 , Issue.2 , pp. 376-386
    • Dazert, E.1    Neumann-Haefelin, C.2    Bressanelli, S.3    Fitzmaurice, K.4    Kort, J.5
  • 16
    • 0036045424 scopus 로고    scopus 로고
    • HLA B27 in health and disease: A double-edged sword?
    • Bowness P. 2002. HLA B27 in health and disease: a double-edged sword? Rheumatology 41(8):857. 68
    • (2002) Rheumatology , vol.41 , Issue.8 , pp. 857-868
    • Bowness, P.1
  • 17
    • 0029902892 scopus 로고    scopus 로고
    • A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B2705
    • Peruzzi M, Wagtmann N, Long EO. 1996. A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B. 2705. J. Exp. Med. 184(4):1585. 90
    • (1996) J. Exp. Med. , vol.184 , Issue.4 , pp. 1585-1590
    • Peruzzi, M.1    Wagtmann, N.2    Long, E.O.3
  • 18
    • 0028920065 scopus 로고
    • Peptide specificity in the recognition of MHC class i by natural killer cell clones
    • Malnati MS, Peruzzi M, Parker KC, Biddison WE, Ciccone E, et al. 1995. Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science 267(5200):1016. 18
    • (1995) Science , vol.267 , Issue.5200 , pp. 1016-1018
    • Malnati, M.S.1    Peruzzi, M.2    Parker, K.C.3    Biddison, W.E.4    Ciccone, E.5
  • 20
    • 0032036434 scopus 로고    scopus 로고
    • Cutting edge: Human myelomonocytic cells express an inhibitory receptor for classical and nonclassicalMHCclass Imolecules
    • Colonna M, Samaridis J, Cella M, Angman L, Allen RL, et al. 1998. Cutting edge: Human myelomonocytic cells express an inhibitory receptor for classical and nonclassicalMHCclass Imolecules. J. Immunol. 160(7):3096. 100
    • (1998) J. Immunol. , vol.160 , Issue.7 , pp. 3096-3100
    • Colonna, M.1    Samaridis, J.2    Cella, M.3    Angman, L.4    Allen, R.L.5
  • 21
    • 84897386464 scopus 로고    scopus 로고
    • LILRB2 interaction withHLA class i correlates with control of HIV-1 infection
    • Bashirova AA, Martin-Gayo E, Jones DC,Qi Y, Apps R, et al. 2014. LILRB2 interaction withHLA class I correlates with control of HIV-1 infection. PLOS Genet. 10(3):e1004196
    • (2014) PLOS Genet. , vol.10 , Issue.3 , pp. e1004196
    • Bashirova, A.A.1    Martin-Gayo, E.2    Jones, D.C.3    Qi, Y.4    Apps, R.5
  • 22
    • 0028082509 scopus 로고
    • A subset of HLA-B27 molecules contains peptides much longer than nonamers
    • Urban RG, Chicz RM, LaneWS, Strominger JL, Rehm A, et al. 1994. A subset of HLA-B27 molecules contains peptides much longer than nonamers. PNAS 91(4):1534. 38
    • (1994) PNAS , vol.91 , Issue.4 , pp. 1534-1538
    • Urban, R.G.1    Chicz, R.M.2    Lane, W.S.3    Strominger, J.L.4    Rehm, A.5
  • 23
    • 0037108486 scopus 로고    scopus 로고
    • Uniquely conformed peptidecontaining β2-microglobulin-free heavy chains of HLA-B2705 on the cell surface
    • Malik P, Klimovitsky P, Deng L-W, Boyson JE, Strominger JL. 2002. Uniquely conformed peptidecontaining β2-microglobulin-free heavy chains of HLA-B2705 on the cell surface. J. Immunol. Baltim. Md 1950 169(8):4379. 87
    • (2002) J. Immunol. Baltim. Md 1950 , vol.169 , Issue.8 , pp. 4379-4387
    • Malik, P.1    Klimovitsky, P.2    Deng, L.-W.3    Boyson, J.E.4    Strominger, J.L.5
  • 24
  • 25
    • 0346734194 scopus 로고    scopus 로고
    • Fully functional HLA B27-restricted CD4+ as well as CD8+ T cell responses in TCR transgenic mice
    • Roddis M, Carter RW, Sun M-Y,Weissensteiner T, McMichael AJ, et al. 2004. Fully functional HLA B27-restricted CD4+ as well as CD8+ T cell responses in TCR transgenic mice. J. Immunol. 1950 172(1):155. 61
    • (2004) J. Immunol. 1950 , vol.172 , Issue.1 , pp. 155-161
    • Roddis, M.1    Carter, R.W.2    Sun, M.-Y.3    Weissensteiner, T.4    McMichael, A.J.5
  • 26
    • 84862979660 scopus 로고    scopus 로고
    • Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
    • Illing PT, Vivian JP, Dudek NL, Kostenko L, Chen Z, et al. 2012. Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature 486(7404):554. 58
    • (2012) Nature , vol.486 , Issue.7404 , pp. 554-558
    • Illing, P.T.1    Vivian, J.P.2    Dudek, N.L.3    Kostenko, L.4    Chen, Z.5
  • 27
    • 0025358734 scopus 로고
    • Activated humanTlymphocytes express MHC class i heavy chains not associated with β2-microglobulin
    • Schnabl E, Stockinger H, Majdic O, Gaugitsch H, Lindley IJ, et al. 1990. Activated humanTlymphocytes express MHC class I heavy chains not associated with β2-microglobulin. J. Exp. Med. 171(5):1431. 42
    • (1990) J. Exp. Med. , vol.171 , Issue.5 , pp. 1431-1442
    • Schnabl, E.1    Stockinger, H.2    Majdic, O.3    Gaugitsch, H.4    Lindley, I.J.5
  • 28
    • 0027302856 scopus 로고
    • The soluble pool of beta microglobulin free HLA class i alpha-chains: Qualitative and quantitative characterization
    • Pickl WF, Majdic O, Faé I, Reuschel R, Holter W, Knapp W. 1993. The soluble pool of beta microglobulin free HLA class I alpha-chains: qualitative and quantitative characterization. J. Immunol. 151(5):2613. 22
    • (1993) J. Immunol. , vol.151 , Issue.5 , pp. 2613-2622
    • Pickl, W.F.1    Majdic, O.2    Faé, I.3    Reuschel, R.4    Holter, W.5    Knapp, W.6
  • 29
    • 84899426320 scopus 로고    scopus 로고
    • Synapse elimination and learning rules co-regulated by MHC class i H2-Db
    • Lee H, Brott BK, Kirkby LA, Adelson JD, Cheng S, et al. 2014. Synapse elimination and learning rules co-regulated by MHC class I H2-Db. Nature 509(7499):195. 200
    • (2014) Nature , vol.509 , Issue.7499 , pp. 195-200
    • Lee, H.1    Brott, B.K.2    Kirkby, L.A.3    Adelson, J.D.4    Cheng, S.5
  • 30
    • 84988295459 scopus 로고    scopus 로고
    • Sexual selection explains more functional variation in the mammalian major histocompatibility complex than parasitism
    • Winternitz JC, Minchey SG, Garamszegi LZ, Huang S, Stephens PR, Altizer S. 2013. Sexual selection explains more functional variation in the mammalian major histocompatibility complex than parasitism. Proc. R. Soc. B 280(1769):20131605
    • (2013) Proc. R. Soc. B , vol.280 , Issue.1769 , pp. 20131605
    • Winternitz, J.C.1    Minchey, S.G.2    Garamszegi, L.Z.3    Huang, S.4    Stephens, P.R.5    Altizer, S.6
  • 31
    • 84925688578 scopus 로고    scopus 로고
    • Prevalence of spondyloarthritis in reference to HLA-B27 in the French population: Results of the GAZEL cohort
    • In press
    • Costantino F, Talpin A, Said-Nahal R,Goldberg M, Henny J, et al. 2013. Prevalence of spondyloarthritis in reference to HLA-B27 in the French population: results of the GAZEL cohort. Ann. Rheum. Dis. In press. doi: 10. 1136/annrheumdis-2013-204436
    • (2013) Ann. Rheum. Dis.
    • Costantino, F.1    Talpin, A.2    Said-Nahal, R.3    Goldberg, M.4    Henny, J.5
  • 32
    • 79953190459 scopus 로고    scopus 로고
    • Epidemiology of spondyloarthritis in North America
    • Reveille JD. 2011. Epidemiology of spondyloarthritis in North America. Am. J. Med. Sci. 341(4):284-86
    • (2011) Am. J. Med. Sci. , vol.341 , Issue.4 , pp. 284-286
    • Reveille, J.D.1
  • 34
    • 79960899377 scopus 로고    scopus 로고
    • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
    • Evans DM, Spencer CCA, Pointon JJ, Su Z, Harvey D, et al. 2011. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat. Genet. 43(8):761-67
    • (2011) Nat. Genet. , vol.43 , Issue.8 , pp. 761-767
    • Evans, D.M.1    Spencer, C.C.A.2    Pointon, J.J.3    Su, Z.4    Harvey, D.5
  • 35
    • 84879691837 scopus 로고    scopus 로고
    • Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
    • Int. Genet. Ankyl. Spondylitis Consort. (IGAS), Cortes A, Hadler J, Pointon JP, Robinson PC, et al. 2013. Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat. Genet. 45(7):730-38
    • (2013) Nat. Genet. , vol.45 , Issue.7 , pp. 730-738
    • Int. Genet. Ankyl. Spondylitis Consort. (IGAS)1    Cortes, A.2    Hadler, J.3    Pointon, J.P.4    Robinson, P.C.5
  • 36
    • 0015840838 scopus 로고
    • Human lymphocyte antigen association in ankylosing spondylitis
    • CaffreyMF, James DC. 1973. Human lymphocyte antigen association in ankylosing spondylitis. Nature 242(5393):121
    • (1973) Nature , vol.242 , Issue.5393 , pp. 121
    • Caffrey, M.F.1    James, D.C.2
  • 37
    • 0015914854 scopus 로고
    • High association of AN HL-A antigen, W27, with ankylosing spondylitis
    • Schlosstein L, Terasaki PI, Bluestone R, Pearson CM. 1973. High association of AN HL-A antigen, W27, with ankylosing spondylitis. N. Engl. J. Med. 288(14):704-6
    • (1973) N. Engl. J. Med. , vol.288 , Issue.14 , pp. 704-706
    • Schlosstein, L.1    Terasaki, P.I.2    Bluestone, R.3    Pearson, C.M.4
  • 39
    • 84918829479 scopus 로고    scopus 로고
    • Prevalence of extra-articular manifestations in patients with ankylosing spondylitis: A systematic review and meta-analysis
    • Stolwijk C, van Tubergen A, Castillo-Ortiz JD, Boonen A. 2015. Prevalence of extra-articular manifestations in patients with ankylosing spondylitis: a systematic review and meta-analysis. Ann. Rheum. Dis. 74(1):65-73
    • (2015) Ann. Rheum. Dis. , vol.74 , Issue.1 , pp. 65-73
    • Stolwijk, C.1    Van Tubergen, A.2    Castillo-Ortiz, J.D.3    Boonen, A.4
  • 41
    • 0029879899 scopus 로고    scopus 로고
    • HLA class i associations of ankylosing spondylitis in the white population in the United Kingdom
    • BrownMA, Pile KD, Kennedy LG, Calin A, Darke C, et al. 1996. HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom. Ann. Rheum. Dis. 55(4):268-70
    • (1996) Ann. Rheum. Dis. , vol.55 , Issue.4 , pp. 268-270
    • Brown, M.A.1    Pile, K.D.2    Kennedy, L.G.3    Calin, A.4    Darke, C.5
  • 42
    • 84896414737 scopus 로고    scopus 로고
    • Polymorphism of HLA-B27: 105 subtypes currently known
    • Khan MA. 2013. Polymorphism of HLA-B27: 105 subtypes currently known. Curr. Rheumatol. Rep. 15(10):362
    • (2013) Curr. Rheumatol. Rep. , vol.15 , Issue.10 , pp. 362
    • Khan, M.A.1
  • 43
    • 72649096490 scopus 로고    scopus 로고
    • Predominant association ofHLA-B∗2704 with ankylosing spondylitis in Chinese Han patients
    • Liu Y, Jiang L,Cai Q, Danoy P, BarnardoMCNM, et al. 2010. Predominant association ofHLA-B∗2704 with ankylosing spondylitis in Chinese Han patients. Tissue Antigens 75(1):61-64
    • (2010) Tissue Antigens , vol.75 , Issue.1 , pp. 61-64
    • Liu, Y.1    Jiang, L.2    Cai, Q.3    Danoy, P.4    Barnardo, M.C.N.M.5
  • 44
    • 0028960650 scopus 로고
    • HLA-B27 subtypes in Asian patients with ankylosing spondylitis: Evidence for new associations
    • López-Larrea C, Sujirachato K,Mehra NK, Chiewsilp P, Isarangkura D, et al. 1995. HLA-B27 subtypes in Asian patients with ankylosing spondylitis: Evidence for new associations. Tissue Antigens 45(3):169-76
    • (1995) Tissue Antigens , vol.45 , Issue.3 , pp. 169-176
    • López-Larrea, C.1    Sujirachato, K.2    Mehra, N.K.3    Chiewsilp, P.4    Isarangkura, D.5
  • 45
    • 0028839838 scopus 로고
    • Relevance of residue 116 of HLA-B27 in determining susceptibility to ankylosing spondylitis
    • D'Amato M, Fiorillo MT, Carcassi C, Mathieu A, Zuccarelli A, et al. 1995. Relevance of residue 116 of HLA-B27 in determining susceptibility to ankylosing spondylitis. Eur. J. Immunol. 25(11):3199-201
    • (1995) Eur. J. Immunol. , vol.25 , Issue.11 , pp. 3199-3201
    • D'amato, M.1    Fiorillo, M.T.2    Carcassi, C.3    Mathieu, A.4    Zuccarelli, A.5
  • 46
    • 0031051908 scopus 로고    scopus 로고
    • Susceptibility to ankylosing spondylitis correlates with the C-terminal residue of peptides presented by various HLA-B27 subtypes
    • Fiorillo MT,Meadows L,D'Amato M, Shabanowitz J, Hunt DF, et al. 1997. Susceptibility to ankylosing spondylitis correlates with the C-terminal residue of peptides presented by various HLA-B27 subtypes. Eur. J. Immunol. 27(2):368-73
    • (1997) Eur. J. Immunol. , vol.27 , Issue.2 , pp. 368-373
    • Fiorillo, M.T.1    Meadows, L.2    D'amato, M.3    Shabanowitz, J.4    Hunt, D.F.5
  • 47
    • 0345425057 scopus 로고    scopus 로고
    • High T cell epitope sharing between two HLA-B27 subtypes (B∗2705 and B∗2709) differentially associated to ankylosing spondylitis
    • García-Peydr ó M, Martí M, López de Castro JA. 1999. High T cell epitope sharing between two HLA-B27 subtypes (B∗2705 and B∗2709) differentially associated to ankylosing spondylitis. J. Immunol. 163(4):2299-305
    • (1999) J. Immunol. , vol.163 , Issue.4 , pp. 2299-2305
    • García-Peydr Ó., M.1    Martí, M.2    López De Castro, J.A.3
  • 49
    • 0025234494 scopus 로고
    • Guilt by association: HLA-B27 and ankylosing spondylitis
    • Benjamin R, Parham P. 1990. Guilt by association: HLA-B27 and ankylosing spondylitis. Immunol. Today 11(4):137-42
    • (1990) Immunol. Today , vol.11 , Issue.4 , pp. 137-142
    • Benjamin, R.1    Parham, P.2
  • 50
    • 0025881471 scopus 로고
    • Peptide binding to empty HLA-B27 molecules of viable human cells
    • Benjamin RJ, Madrigal JA, Parham P. 1991. Peptide binding to empty HLA-B27 molecules of viable human cells. Nature 351(6321):74-77
    • (1991) Nature , vol.351 , Issue.6321 , pp. 74-77
    • Benjamin, R.J.1    Madrigal, J.A.2    Parham, P.3
  • 51
    • 0027328672 scopus 로고
    • HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis
    • Hermann E, Yu DT, Meyer zum Büschenfelde KH, Fleischer B. 1993. HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis. Lancet 342(8872):646-50
    • (1993) Lancet , vol.342 , Issue.8872 , pp. 646-650
    • Hermann, E.1    Yu, D.T.2    Meyer Zum Büschenfelde, K.H.3    Fleischer, B.4
  • 52
    • 9144232394 scopus 로고    scopus 로고
    • Use of HLA-B27 tetramers to identify lowfrequency antigen-specificTcells in Chlamydia-triggered reactive arthritis
    • AppelH,KuonW,Kuhne M,WuP, Kuhlmann S, et al. 2004. Use of HLA-B27 tetramers to identify lowfrequency antigen-specificTcells in Chlamydia-triggered reactive arthritis. Arthritis Res. Ther. 6(6):R521. 34
    • (2004) Arthritis Res. Ther. , vol.6 , Issue.6 , pp. R521-R534
    • Appel, H.1    Kuon, W.2    Kuhne, M.3    Wu, P.4    Kuhlmann, S.5
  • 53
    • 0033935853 scopus 로고    scopus 로고
    • CD8+ T-cell autoreactivity to an HLA-B27-restricted self-epitope correlates with ankylosing spondylitis
    • Fiorillo MT, Maragno M, Butler R, Dupuis ML, Sorrentino R. 2000. CD8+ T-cell autoreactivity to an HLA-B27-restricted self-epitope correlates with ankylosing spondylitis. J. Clin. Investig. 106(1):47. 53
    • (2000) J. Clin. Investig. , vol.106 , Issue.1 , pp. 47-53
    • Fiorillo, M.T.1    Maragno, M.2    Butler, R.3    Dupuis, M.L.4    Sorrentino, R.5
  • 54
    • 0030764230 scopus 로고    scopus 로고
    • Multiple T cell expansions are found in the blood and synovial fluid of patients with reactive arthritis
    • Allen RL, Gillespie GM, Hall F, Edmonds S, Hall MA, et al. 1997. Multiple T cell expansions are found in the blood and synovial fluid of patients with reactive arthritis. J. Rheumatol. 24(9):1750. 57
    • (1997) J. Rheumatol. , vol.24 , Issue.9 , pp. 1750-1757
    • Allen, R.L.1    Gillespie, G.M.2    Hall, F.3    Edmonds, S.4    Hall, M.A.5
  • 55
    • 0036818765 scopus 로고    scopus 로고
    • Conserved TCR βchain usage in reactive arthritis; Evidence for selection by a putativeHLA-B27-associated autoantigen
    • May E, Dulphy N, Frauendorf E, Duchmann R, Bowness P, et al. 2002. Conserved TCR βchain usage in reactive arthritis; evidence for selection by a putativeHLA-B27-associated autoantigen. Tissue Antigens 60(4):299. 308
    • (2002) Tissue Antigens , vol.60 , Issue.4 , pp. 299-308
    • May, E.1    Dulphy, N.2    Frauendorf, E.3    Duchmann, R.4    Bowness, P.5
  • 56
    • 70249113699 scopus 로고    scopus 로고
    • Individual characterization of stably expanded T cell clones in ankylosing spondylitis patients
    • Mamedov IZ, Britanova OV, Chkalina AV, Staroverov DB, Amosova AL, et al. 2009. Individual characterization of stably expanded T cell clones in ankylosing spondylitis patients. Autoimmunity 42(6):525. 36
    • (2009) Autoimmunity , vol.42 , Issue.6 , pp. 525-536
    • Mamedov, I.Z.1    Britanova, O.V.2    Chkalina, A.V.3    Staroverov, D.B.4    Amosova, A.L.5
  • 57
    • 0037438486 scopus 로고    scopus 로고
    • CD8αβT cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats
    • May E, Dorris ML, Satumtira N, Iqbal I, Rehman MI, et al. 2003. CD8αβT cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats. J. Immunol. 170(2):1099. 105
    • (2003) J. Immunol. , vol.170 , Issue.2 , pp. 1099-1105
    • May, E.1    Dorris, M.L.2    Satumtira, N.3    Iqbal, I.4    Rehman, M.I.5
  • 58
    • 67650074528 scopus 로고    scopus 로고
    • Spondylarthritis in HLAB27/ human β2-microglobulin-transgenic rats is not prevented by lack of CD8
    • Taurog JD, Dorris ML, Satumtira N, Tran TM, Sharma R, et al. 2009. Spondylarthritis in HLAB27/ human β2-microglobulin-transgenic rats is not prevented by lack of CD8. Arthritis Rheumatol. 60(7):1977. 84
    • (2009) Arthritis Rheumatol. , vol.60 , Issue.7 , pp. 1977-1984
    • Taurog, J.D.1    Dorris, M.L.2    Satumtira, N.3    Tran, T.M.4    Sharma, R.5
  • 59
    • 84863697312 scopus 로고    scopus 로고
    • Il-23 induces spondyloarthropathy by acting on ROR-αt+ CD3+CD4. CD8. Entheseal resident T cells
    • Sherlock JP, Joyce-Shaikh B, Turner SP, Chao C-C, Sathe M, et al. 2012. Il-23 induces spondyloarthropathy by acting on ROR-αt+ CD3+CD4. CD8. entheseal resident T cells. Nat. Med. 18(7):1069. 76
    • (2012) Nat. Med. , vol.18 , Issue.7 , pp. 1069-1076
    • Sherlock, J.P.1    Joyce-Shaikh, B.2    Turner, S.P.3    Chao, C.-C.4    Sathe, M.5
  • 60
    • 0033136630 scopus 로고    scopus 로고
    • Cutting edge: HLA-B27 can form a novel β2-microglobulin-free heavy chain homodimer structure
    • Allen RL, O'Callaghan CA, McMichael AJ, Bowness P. 1999. Cutting edge: HLA-B27 can form a novel β2-microglobulin-free heavy chain homodimer structure. J. Immunol. 162(9):5045. 48
    • (1999) J. Immunol. , vol.162 , Issue.9 , pp. 5045-5048
    • Allen, R.L.1    O'callaghan, C.A.2    McMichael, A.J.3    Bowness, P.4
  • 61
    • 0032742012 scopus 로고    scopus 로고
    • Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies
    • Mear JP, Schreiber KL, Munz C, Zhu X, Stevanovilc S, et al. 1999. Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies. J. Immunol. 163(12):6665. 70
    • (1999) J. Immunol. , vol.163 , Issue.12 , pp. 6665-6670
    • Mear, J.P.1    Schreiber, K.L.2    Munz, C.3    Zhu, X.4    Stevanovilc, S.5
  • 62
    • 1542305542 scopus 로고    scopus 로고
    • Formation of HLA-B27 homodimers and their relationship to assembly kinetics
    • Antoniou AN, Ford S, Taurog JD, Butcher GW, Powis SJ. 2004. Formation of HLA-B27 homodimers and their relationship to assembly kinetics. J. Biol. Chem. 279(10):8895. 902
    • (2004) J. Biol. Chem. , vol.279 , Issue.10 , pp. 8895-8902
    • Antoniou, A.N.1    Ford, S.2    Taurog, J.D.3    Butcher, G.W.4    Powis, S.J.5
  • 63
    • 33846194065 scopus 로고    scopus 로고
    • HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease
    • Turner MJ, Delay ML, Bai S, Klenk E, Colbert RA. 2007. HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: implications for the pathogenesis of spondylarthritis-like disease. Arthritis Rheumatol. 56(1):215. 23
    • (2007) Arthritis Rheumatol. , vol.56 , Issue.1 , pp. 215-223
    • Turner, M.J.1    Delay, M.L.2    Bai, S.3    Klenk, E.4    Colbert, R.A.5
  • 64
    • 69449086287 scopus 로고    scopus 로고
    • HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with th17 activation in transgenic rats
    • DeLayML, Turner MJ, Klenk EI, Smith JA, Sowders DP, Colbert RA. 2009. HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with th17 activation in transgenic rats. Arthritis Rheumatol. 60(9):2633. 43
    • (2009) Arthritis Rheumatol. , vol.60 , Issue.9 , pp. 2633-2643
    • Delay, M.L.1    Turner, M.J.2    Klenk, E.I.3    Smith, J.A.4    Sowders, D.P.5    Colbert, R.A.6
  • 65
    • 84867525970 scopus 로고    scopus 로고
    • Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis
    • Utriainen L, Firmin D, Wright P, Cerovic V, Breban M, et al. 2012. Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis. Arthritis Rheumatol. 64(10):3199. 209
    • (2012) Arthritis Rheumatol. , vol.64 , Issue.10 , pp. 3199-3209
    • Utriainen, L.1    Firmin, D.2    Wright, P.3    Cerovic, V.4    Breban, M.5
  • 66
    • 84881362894 scopus 로고    scopus 로고
    • HLA-B27 alters the response to tumor necrosis factor α and promotes osteoclastogenesis in bone marrow monocytes from HLA-B27-transgenic rats
    • Layh-Schmitt G, Yang EY, Kwon G, Colbert RA. 2013. HLA-B27 alters the response to tumor necrosis factor α and promotes osteoclastogenesis in bone marrow monocytes from HLA-B27-transgenic rats. Arthritis Rheumatol. 65(8):2123. 31
    • (2013) Arthritis Rheumatol. , vol.65 , Issue.8 , pp. 2123-2131
    • Layh-Schmitt, G.1    Yang, E.Y.2    Kwon, G.3    Colbert, R.A.4
  • 67
    • 78049271424 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression
    • Goodall JC, Wu C, Zhang Y, McNeill L, Ellis L, et al. 2010. Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression. PNAS 107(41):17698. 703
    • (2010) PNAS , vol.107 , Issue.41 , pp. 17698-17703
    • Goodall, J.C.1    Wu, C.2    Zhang, Y.3    McNeill, L.4    Ellis, L.5
  • 68
    • 84880672279 scopus 로고    scopus 로고
    • Altered regulation of ELAVL1/HuR in HLA-B27-expressing U937 monocytic cells
    • Sahlberg AS, Ruuska M, Granfors K, Penttinen MA. 2013. Altered regulation of ELAVL1/HuR in HLA-B27-expressing U937 monocytic cells. PLOS ONE 8(7):e70377
    • (2013) PLOS ONE , vol.8 , Issue.7 , pp. e70377
    • Sahlberg, A.S.1    Ruuska, M.2    Granfors, K.3    Penttinen, M.A.4
  • 69
    • 73249153202 scopus 로고    scopus 로고
    • From HLA-B27 to spondyloarthritis: A journey through the ER
    • Colbert RA, DeLay ML, Klenk EI, Layh-Schmitt G. 2010. From HLA-B27 to spondyloarthritis: a journey through the ER. Immunol. Rev. 233(1):181. 202
    • (2010) Immunol. Rev. , vol.233 , Issue.1 , pp. 181-202
    • Colbert, R.A.1    Delay, M.L.2    Klenk, E.I.3    Layh-Schmitt, G.4
  • 70
    • 33645852216 scopus 로고    scopus 로고
    • Additional human β2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats
    • Tran TM, Dorris ML, Satumtira N, Richardson JA, Hammer RE, et al. 2006. Additional human β2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats. Arthritis Rheumatol. 54(4):1317. 27
    • (2006) Arthritis Rheumatol. , vol.54 , Issue.4 , pp. 1317-1327
    • Tran, T.M.1    Dorris, M.L.2    Satumtira, N.3    Richardson, J.A.4    Hammer, R.E.5
  • 71
    • 79957819259 scopus 로고    scopus 로고
    • Expression of MHC class i dimers and ERAP1 in an ankylosing spondylitis patient cohort
    • Campbell EC, Fettke F, Bhat S, Morley KD, Powis SJ. 2011. Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort. Immunology 133(3):379. 85
    • (2011) Immunology , vol.133 , Issue.3 , pp. 379-385
    • Campbell, E.C.1    Fettke, F.2    Bhat, S.3    Morley, K.D.4    Powis, S.J.5
  • 72
    • 84903907928 scopus 로고    scopus 로고
    • Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation
    • Ciccia F, Accardo-Palumbo A, Rizzo A, Guggino G, Raimondo S, et al. 2013. Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. Ann. Rheum. Dis. 73:1566. 74
    • (2013) Ann. Rheum. Dis. , vol.73 , pp. 1566-1574
    • Ciccia, F.1    Accardo-Palumbo, A.2    Rizzo, A.3    Guggino, G.4    Raimondo, S.5
  • 73
    • 56249104422 scopus 로고    scopus 로고
    • Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis
    • Dong W, Zhang Y, Yan M, LiuH,Chen Z, Zhu P. 2008. Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis. Scand. J. Rheumatol. 37(6):427-34
    • (2008) Scand. J. Rheumatol. , vol.37 , Issue.6 , pp. 427-434
    • Dong, W.1    Zhang, Y.2    Yan, M.3    Liu, H.4    Chen, Z.5    Zhu, P.6
  • 74
    • 0037352755 scopus 로고    scopus 로고
    • Lymphoblastoid cells expressHLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling
    • Bird LA, Peh CA, Kollnberger S, Elliott T, McMichael AJ, Bowness P. 2003. Lymphoblastoid cells expressHLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling. Eur. J. Immunol. 33(3):748-59
    • (2003) Eur. J. Immunol. , vol.33 , Issue.3 , pp. 748-759
    • Bird, L.A.1    Peh, C.A.2    Kollnberger, S.3    Elliott, T.4    McMichael, A.J.5    Bowness, P.6
  • 75
    • 0036846149 scopus 로고    scopus 로고
    • Cell-surface expression and immune receptor recognition of HLA-B27 homodimers
    • Kollnberger S, Bird L, SunM-Y, Retiere C, Braud VM, et al. 2002. Cell-surface expression and immune receptor recognition of HLA-B27 homodimers. Arthritis Rheumatol. 46(11):2972-82
    • (2002) Arthritis Rheumatol. , vol.46 , Issue.11 , pp. 2972-2982
    • Kollnberger, S.1    Bird, L.2    Sun, M.-Y.3    Retiere, C.4    Braud, V.M.5
  • 76
    • 3242798755 scopus 로고    scopus 로고
    • HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors
    • Kollnberger S, Bird LA, Roddis M, Hacquard-Bouder C, Kubagawa H, et al. 2004. HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors. J. Immunol. 173(3):1699-710
    • (2004) J. Immunol. , vol.173 , Issue.3 , pp. 1699-1710
    • Kollnberger, S.1    Bird, L.A.2    Roddis, M.3    Hacquard-Bouder, C.4    Kubagawa, H.5
  • 77
    • 84862597826 scopus 로고    scopus 로고
    • HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class i
    • Giles J, Shaw J, Piper C, Wong-Baeza I, McHugh K, et al. 2012. HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I. J. Immunol. 188(12):6184-93
    • (2012) J. Immunol. , vol.188 , Issue.12 , pp. 6184-6193
    • Giles, J.1    Shaw, J.2    Piper, C.3    Wong-Baeza, I.4    McHugh, K.5
  • 78
    • 84875448412 scopus 로고    scopus 로고
    • KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class i and promotes the expansion of T cells in ankylosing spondylitis
    • Wong-Baeza I, Ridley A, Shaw J,HatanoH, Rysnik O, et al. 2013. KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis. J. Immunol. 190(7):3216-24
    • (2013) J. Immunol. , vol.190 , Issue.7 , pp. 3216-3224
    • Wong-Baeza, I.1    Ridley, A.2    Shaw, J.3    Hatano, H.4    Rysnik, O.5
  • 79
    • 27744513659 scopus 로고    scopus 로고
    • Expansion and enhanced survival of natural killer cells expressing the killer immunoglobulin-like receptor KIR3DL2 in spondylarthritis
    • Chan AT, Kollnberger SD, Wedderburn LR, Bowness P. 2005. Expansion and enhanced survival of natural killer cells expressing the killer immunoglobulin-like receptor KIR3DL2 in spondylarthritis. Arthritis Rheumatol. 52(11):3586-95
    • (2005) Arthritis Rheumatol. , vol.52 , Issue.11 , pp. 3586-3595
    • Chan, A.T.1    Kollnberger, S.D.2    Wedderburn, L.R.3    Bowness, P.4
  • 80
    • 79951835541 scopus 로고    scopus 로고
    • Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis
    • Bowness P,Ridley A, Shaw J,Chan AT, Wong-Baeza I, et al. 2011. Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis. J. Immunol. 186(4):2672-80
    • (2011) J. Immunol. , vol.186 , Issue.4 , pp. 2672-2680
    • Bowness, P.1    Ridley, A.2    Shaw, J.3    Chan, A.T.4    Wong-Baeza, I.5
  • 81
    • 0036246467 scopus 로고    scopus 로고
    • Free HLA class i heavy chain-carrying monocytes- A potential role in the pathogenesis of spondyloarthropathies
    • Tsai WC, Chen CJ, Yen JH, Ou TT, Tsai JJ, et al. 2002. Free HLA class I heavy chain-carrying monocytes- A potential role in the pathogenesis of spondyloarthropathies. J. Rheumatol. 29(5):966-72
    • (2002) J. Rheumatol. , vol.29 , Issue.5 , pp. 966-972
    • Tsai, W.C.1    Chen, C.J.2    Yen, J.H.3    Ou, T.T.4    Tsai, J.J.5
  • 82
    • 33750201148 scopus 로고    scopus 로고
    • Consistent patterns of expression of HLA class i free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles
    • Raine T, Brown D, Bowness P, Hill Gaston JS,Moffett A, et al. 2006. Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles. Rheumatology 45(11):1338-44
    • (2006) Rheumatology , vol.45 , Issue.11 , pp. 1338-1344
    • Raine, T.1    Brown, D.2    Bowness, P.3    Hill Gaston, J.S.4    Moffett, A.5
  • 83
    • 0022533999 scopus 로고
    • Monoclonal antibodies raised against denaturedHLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products
    • Stam NJ, Spits H, Ploegh HL. 1986. Monoclonal antibodies raised against denaturedHLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products. J. Immunol. 137(7):2299-306
    • (1986) J. Immunol. , vol.137 , Issue.7 , pp. 2299-2306
    • Stam, N.J.1    Spits, H.2    Ploegh, H.L.3
  • 85
    • 84873725322 scopus 로고    scopus 로고
    • Microscopic gut inflammation in axial spondyloarthritis: A multiparametric predictive model
    • Van Praet L, Van den Bosch FE, Jacques P, Carron P, Jans L, et al. 2013. Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model. Ann. Rheum. Dis. 72(3):414-17
    • (2013) Ann. Rheum. Dis. , vol.72 , Issue.3 , pp. 414-417
    • Van Praet, L.1    Van Den Bosch, F.E.2    Jacques, P.3    Carron, P.4    Jans, L.5
  • 86
    • 84920951756 scopus 로고    scopus 로고
    • HLA-B27 and human β2-microglobulin affect the gut microbiota of transgenic rats
    • Lin P, Bach M, Asquith M, Lee AY, Akileswaran L, et al. 2014. HLA-B27 and human β2-microglobulin affect the gut microbiota of transgenic rats. PLOS ONE 9(8):e105684
    • (2014) PLOS ONE , vol.9 , Issue.8 , pp. e105684
    • Lin, P.1    Bach, M.2    Asquith, M.3    Lee, A.Y.4    Akileswaran, L.5
  • 87
    • 4544369464 scopus 로고    scopus 로고
    • HLA-B27 lacking associated β2-microglobulin rearranges to auto-display or cross-display residues 169-181: A novel molecular mechanism for spondyloarthropathies
    • Luthra-Guptasarma M, Singh B. 2004. HLA-B27 lacking associated β2-microglobulin rearranges to auto-display or cross-display residues 169-181: a novel molecular mechanism for spondyloarthropathies. FEBS Lett. 575(1-3):1-8
    • (2004) FEBS Lett. , vol.575 , Issue.1-3 , pp. 1-8
    • Luthra-Guptasarma, M.1    Singh, B.2
  • 88
    • 0037289693 scopus 로고    scopus 로고
    • Ankylosing spondylitis: A β2m-deposition disease?
    • Uchanska-Ziegler B, ZieglerA. 2003. Ankylosing spondylitis: a β2m-deposition disease? Trends Immunol. 24(2):73-76
    • (2003) Trends Immunol. , vol.24 , Issue.2 , pp. 73-76
    • Uchanska-Ziegler, B.1    Ziegler, A.2
  • 89
    • 0023245617 scopus 로고
    • HLA-restricted recognition of viral antigens in HLA transgenic mice
    • Kievits F, Ivanyi P, Krimpenfort P, Berns A, Ploegh HL. 1987. HLA-restricted recognition of viral antigens in HLA transgenic mice. Nature 329(6138):447-49
    • (1987) Nature , vol.329 , Issue.6138 , pp. 447-449
    • Kievits, F.1    Ivanyi, P.2    Krimpenfort, P.3    Berns, A.4    Ploegh, H.L.5
  • 90
    • 0030482194 scopus 로고    scopus 로고
    • HLA-B27 heavy chains contribute to spontaneous inflammatory disease in B27/human β2-microglobulin (β2m) double transgenic mice with disrupted mouse β2m
    • Khare SD, Hansen J, Luthra HS, David CS. 1996. HLA-B27 heavy chains contribute to spontaneous inflammatory disease in B27/human β2-microglobulin (β2m) double transgenic mice with disrupted mouse β2m. J. Clin. Investig. 98(12):2746-55
    • (1996) J. Clin. Investig. , vol.98 , Issue.12 , pp. 2746-2755
    • Khare, S.D.1    Hansen, J.2    Luthra, H.S.3    David, C.S.4
  • 91
    • 0033789614 scopus 로고    scopus 로고
    • Development of spontaneous arthritis in β2-microglobulin-deficient mice without expression of HLA-B27: Association with deficiency of endogenous major histocompatibility complex class i expression
    • Kingsbury DJ, Mear JP, Witte DP, Taurog JD, Roopenian DC, Colbert RA. 2000. Development of spontaneous arthritis in β2-microglobulin-deficient mice without expression of HLA-B27: association with deficiency of endogenous major histocompatibility complex class I expression. Arthritis Rheumatol. 43(10):2290-96
    • (2000) Arthritis Rheumatol. , vol.43 , Issue.10 , pp. 2290-2296
    • Kingsbury, D.J.1    Mear, J.P.2    Witte, D.P.3    Taurog, J.D.4    Roopenian, D.C.5    Colbert, R.A.6
  • 92
    • 0025633436 scopus 로고
    • Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and humanβ2m: An animal model ofHLA-B27-associated human disorders
    • Hammer RE, Maika SD, Richardson JA, Tang JP, Taurog JD. 1990. Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and humanβ2m: an animal model ofHLA-B27-associated human disorders. Cell 63(5):1099-112
    • (1990) Cell , vol.63 , Issue.5 , pp. 1099-1112
    • Hammer, R.E.1    Maika, S.D.2    Richardson, J.A.3    Tang, J.P.4    Taurog, J.D.5
  • 93
    • 0027453544 scopus 로고
    • Transfer of the inflammatory disease of HLA-B27 transgenic rats by bone marrow engraftment
    • Breban M, Hammer RE, Richardson JA, Taurog JD. 1993. Transfer of the inflammatory disease of HLA-B27 transgenic rats by bone marrow engraftment. J. Exp. Med. 178(5):1607. 16
    • (1993) J. Exp. Med. , vol.178 , Issue.5 , pp. 1607-1616
    • Breban, M.1    Hammer, R.E.2    Richardson, J.A.3    Taurog, J.D.4
  • 94
    • 3543113108 scopus 로고    scopus 로고
    • The specificity of peptides bound to human histocompatibility leukocyte antigen (HLA)-B27 influences the prevalence of arthritis in HLAB27 transgenic rats
    • Zhou M, Sayad A, Simmons WA, Jones RC,Maika SD, et al. 1998. The specificity of peptides bound to human histocompatibility leukocyte antigen (HLA)-B27 influences the prevalence of arthritis in HLAB27 transgenic rats. J. Exp. Med. 188(5):877. 86
    • (1998) J. Exp. Med. , vol.188 , Issue.5 , pp. 877-886
    • Zhou, M.1    Sayad, A.2    Simmons, W.A.3    Jones, R.C.4    Maika, S.D.5
  • 96
    • 84873091770 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis betweenHLA-B. 51 andERAP1
    • Kirino Y, Bertsias G, Ishigatsubo Y, Mizuki N, Tugal-Tutkun I, et al. 2013. Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis betweenHLA-B. 51 andERAP1. Nat. Genet. 45(2):202. 7
    • (2013) Nat. Genet. , vol.45 , Issue.2 , pp. 202-207
    • Kirino, Y.1    Bertsias, G.2    Ishigatsubo, Y.3    Mizuki, N.4    Tugal-Tutkun, I.5
  • 97
    • 79956348710 scopus 로고    scopus 로고
    • Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
    • Kochan G, Krojer T, Harvey D, Fischer R, Chen L, et al. 2011. Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. PNAS 108(19):7745. 50
    • (2011) PNAS , vol.108 , Issue.19 , pp. 7745-7750
    • Kochan, G.1    Krojer, T.2    Harvey, D.3    Fischer, R.4    Chen, L.5
  • 98
    • 79957819259 scopus 로고    scopus 로고
    • Expression of MHC class i dimers and ERAP1 in an ankylosing spondylitis patient cohort
    • Campbell EC, Fettke F, Bhat S, Morley KD, Powis SJ. 2011. Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort. Immunology 133(3):379. 85
    • (2011) Immunology , vol.133 , Issue.3 , pp. 379-385
    • Campbell, E.C.1    Fettke, F.2    Bhat, S.3    Morley, K.D.4    Powis, S.J.5
  • 99
    • 33846233912 scopus 로고    scopus 로고
    • ERAAP synergizes with MHC class i molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum
    • Kanaseki T, Blanchard N, Hammer GE, Gonzalez F, Shastri N. 2006. ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum. Immunity 25(5):795. 806
    • (2006) Immunity , vol.25 , Issue.5 , pp. 795-806
    • Kanaseki, T.1    Blanchard, N.2    Hammer, G.E.3    Gonzalez, F.4    Shastri, N.5
  • 100
    • 84880816750 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens
    • Seregin SS, Rastall DPW, Evnouchidou I, Aylsworth CF, Quiroga D, et al. 2013. Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens. Autoimmunity 46(8):497. 508
    • (2013) Autoimmunity , vol.46 , Issue.8 , pp. 497-508
    • Seregin, S.S.1    Rastall, D.P.W.2    Evnouchidou, I.3    Aylsworth, C.F.4    Quiroga, D.5
  • 101
    • 33846988640 scopus 로고    scopus 로고
    • In the absence of aminopeptidase ERAAP, MHCclass Imolecules presentmany unstable and highly immunogenic peptides
    • HammerGE, Gonzalez F, James E, Nolla H, Shastri N. 2007. In the absence of aminopeptidase ERAAP, MHCclass Imolecules presentmany unstable and highly immunogenic peptides. Nat. Immunol. 8(1):101. 8
    • (2007) Nat. Immunol. , vol.8 , Issue.1 , pp. 101-108
    • Hammer, G.E.1    Gonzalez, F.2    James, E.3    Nolla, H.4    Shastri, N.5
  • 102
    • 84896269583 scopus 로고    scopus 로고
    • Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented byHLA-B27
    • Chen L, Fischer R, Peng Y, Reeves E, McHugh K, et al. 2014. Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented byHLA-B27. Arthritis Rheumatol. 66(2):284. 94
    • (2014) Arthritis Rheumatol. , vol.66 , Issue.2 , pp. 284-294
    • Chen, L.1    Fischer, R.2    Peng, Y.3    Reeves, E.4    McHugh, K.5
  • 103
    • 84921561531 scopus 로고    scopus 로고
    • Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis
    • Kenna TJ, Lau MC, Keith P, Ciccia F, Costello M-E, et al. 2015. Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis. Genes Immun. 16(1):35. 42
    • (2015) Genes Immun. , vol.16 , Issue.1 , pp. 35-42
    • Kenna, T.J.1    Lau, M.C.2    Keith, P.3    Ciccia, F.4    Costello, M.-E.5
  • 104
    • 84857924158 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis
    • Haroon N, Tsui FW, Uchanska-Ziegler B, Ziegler A, Inman RD. 2012. Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis. Ann. Rheum. Dis. 71(4):589. 95
    • (2012) Ann. Rheum. Dis. , vol.71 , Issue.4 , pp. 589-595
    • Haroon, N.1    Tsui, F.W.2    Uchanska-Ziegler, B.3    Ziegler, A.4    Inman, R.D.5
  • 105
    • 84889671845 scopus 로고    scopus 로고
    • Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses
    • Zervoudi E, Saridakis E, Birtley JR, Seregin SS, Reeves E, et al. 2013. Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. PNAS 110(49):19890. 95
    • (2013) PNAS , vol.110 , Issue.49 , pp. 19890-19895
    • Zervoudi, E.1    Saridakis, E.2    Birtley, J.R.3    Seregin, S.S.4    Reeves, E.5
  • 106
    • 0016189462 scopus 로고
    • HL-A 27 and arthropathies associated with ulcerative colitis and psoriasis
    • Brewerton DA, Caffrey M, Nicholls A, Walters D, James DC. 1974. HL-A 27 and arthropathies associated with ulcerative colitis and psoriasis. Lancet 1(7864):956. 58
    • (1974) Lancet , vol.1 , Issue.7864 , pp. 956-958
    • Brewerton, D.A.1    Caffrey, M.2    Nicholls, A.3    Walters, D.4    James, D.C.5
  • 107
    • 0036797034 scopus 로고    scopus 로고
    • Juvenile idiopathic arthritis classified by the ILAR criteria: HLA associations in UK patients
    • Thomson W, Barrett JH, Donn R, Pepper L, Kennedy LJ, et al. 2002. Juvenile idiopathic arthritis classified by the ILAR criteria: HLA associations in UK patients. Rheumatology 41(10):1183. 89
    • (2002) Rheumatology , vol.41 , Issue.10 , pp. 1183-1189
    • Thomson, W.1    Barrett, J.H.2    Donn, R.3    Pepper, L.4    Kennedy, L.J.5


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