Prediction of colloidal stability of high concentration protein formulations

Pharmaceutical Development and Technology

Volumn 20, Issue 3, 2015, Pages 367-374

  Garidel, Patrick ^a   Blume, Alfred ^b   Wagner, Michael ^c  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Colloidal stability; DLS; PCS; Protein diffusivity; Protein protein interaction; QELS

Indexed keywords

BUFFER; MONOCLONAL ANTIBODY; POLYSORBATE; PROTEIN; TREHALOSE; COLLOID; SOLUTION AND SOLUBILITY;

ARTICLE; COLLOID; DIFFERENTIAL SCANNING CALORIMETRY; IONIC STRENGTH; LIGHT SCATTERING; NEPHELOMETRY; PH; PHYSICAL STRESS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; THERMODYNAMICS; CHEMISTRY; LIGHT; MEDICINAL CHEMISTRY; OSMOLARITY; PROCEDURES; RADIATION SCATTERING; SOLUTION AND SOLUBILITY;

ANTIBODIES, MONOCLONAL; CHEMISTRY, PHARMACEUTICAL; COLLOIDS; HYDROGEN-ION CONCENTRATION; LIGHT; OSMOLAR CONCENTRATION; PHARMACEUTICAL SOLUTIONS; PROTEIN STABILITY; PROTEINS; SCATTERING, RADIATION; THERMODYNAMICS;

EID: 84927618742     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2013.871032     Document Type: Article

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