Labeled ligand displacement: Extending NMR-based screening of protein targets

ACS Medicinal Chemistry Letters

Volumn 1, Issue 6, 2010, Pages 295-299

  Swann, Steven L ^a   Song, Danying ^a   Sun, Chaohong ^a   Hajduk, Philip J ^a   Petros, Andrew M ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

fragment; labeling; ligand; NMR; screening

Indexed keywords

CARBON 13; CARBONATE DEHYDRATASE; HEAT SHOCK PROTEIN 90; LIGAND;

ANALYTIC METHOD; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HETERONUCLEAR SINGLE QUANTUM COHERENCE; ISOTOPE LABELING; LABELED LIGAND DISPLACEMENT; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN TARGETING;

EID: 77956515615     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml1000849     Document Type: Article

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