Recent advances in lipophilicity measurement by reversed-phase high-performance liquid chromatography

TrAC - Trends in Analytical Chemistry

Volumn 68, Issue , 2015, Pages 28-36

  Liang, Chao ^a   Lian, Hong zhen ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Dissociable compound; Gradient elution; High performance liquid chromatography; Isocratic elution; Lipophilicity; Mobile phase; Mobile phase additive; N octanol water partition coefficient; Retention time correction; Stationary phase

Indexed keywords

ALCOHOLS; CHROMATOGRAPHY; DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS;

DISSOCIABLE COMPOUND; GRADIENT ELUTION; ISOCRATIC ELUTION; LIPOPHILICITY; MOBILE PHASE; MOBILE PHASE ADDITIVES; N-OCTANOL; RETENTION TIME; STATIONARY PHASE;

LIQUID CHROMATOGRAPHY;

CHEMICAL COMPOUND; ORGANIC COMPOUND; POLYMER; SILICON DIOXIDE;

ANALYTICAL PARAMETERS; CONCEPTUAL FRAMEWORK; DEGRADATION; DISTRIBUTION COEFFICIENT; ELUTION; EXPERIMENTAL STUDY; LIPOPHILICITY; MATHEMATICAL COMPUTING; MEASUREMENT; METHODOLOGY; ONLINE ANALYSIS; PARTITION COEFFICIENT; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE PROPERTY RELATION; REPRODUCIBILITY; RETENTION TIME CORRECTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVIEW; SAMPLE SIZE; TIME; VELOCITY;

EID: 84927512551     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2015.02.009     Document Type: Review

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