Effect of n-octanol in the mobile phase on lipophilicity determination by reversed-phase high-performance liquid chromatography on a modified silica column

Journal of Chromatography A

Volumn 1209, Issue 1-2, 2008, Pages 111-119

  Benhaim, Deborah ^a   Grushka, Eli ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Hybrid based reversed phase column; Linear solvation energy relationshiop; Lipophilicity determination; Log k ; Log P; Octanol additive to mobile phase

Indexed keywords

ACIDS; BIOCHEMISTRY; CHROMATOGRAPHIC ANALYSIS; COLUMNS (STRUCTURAL); HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; PH; PH EFFECTS; SILICA;

HYBRID-BASED REVERSED-PHASE COLUMN; LINEAR SOLVATION ENERGY RELATIONSHIOP; LIPOPHILICITY DETERMINATION; LOG P; OCTANOL ADDITIVE TO MOBILE PHASE;

COLUMN CHROMATOGRAPHY;

ACEBUTOLOL; ALPRENOLOL; ATENOLOL; CINCHOCAINE; CORTICOSTERONE; CORTISONE; CORTISONE ACETATE; FENBUFEN; FENOPROFEN CALCIUM; FLURBIPROFEN; HYDROCORTISONE; HYDROCORTISONE ACETATE; IBUPROFEN; INDOPROFEN; LIDOCAINE; METOPROLOL TARTRATE; NADOLOL; NAPROXEN; OCTANOL; PINDOLOL; PREDNISOLONE; PREDNISONE; PRILOCAINE; PROCAINE; PROPRANOLOL; SILICON DIOXIDE; SOTALOL; TETRACAINE;

ARTICLE; LIPOPHILICITY; PARTITION COEFFICIENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; THEORETICAL MODEL;

1-OCTANOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROPHOBICITY; REPRODUCIBILITY OF RESULTS; SILICON DIOXIDE;

EID: 53749085576     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.08.118     Document Type: Article

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