The use of phospholipid modified column for the determination of lipophilic properties in high performance liquid chromatography

Journal of Chromatography A

Volumn 1218, Issue 9, 2011, Pages 1211-1218

  Godard, Tal ^a   Grushka, Eli ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Dynamic coating; Linear solvation energy relationships; Lipophilicity determination; Phospholipid based stationary phase

Indexed keywords

CHROMATOGRAPHIC PROPERTIES; CHROMATOGRAPHIC STATIONARY PHASE; CLOSED LOOPS; COATING SOLUTION; DYNAMIC COATING; EXTRACTION SYSTEMS; GOOD CORRELATIONS; LINEAR SOLVATION ENERGY RELATIONSHIPS; LIPOPHILIC PROPERTIES; LIPOPHILICITY DETERMINATION; OCTANOL/WATER PARTITION COEFFICIENT; P-VALUES; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID-COATING; RETENTION FACTORS; REVERSED PHASE; SHAKE-FLASK METHOD; SYSTEM CONSTANTS;

ALCOHOLS; ALGEBRA; AMIDES; COATINGS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOSOMES; PHOSPHOLIPIDS; SOLVATION;

COLUMN CHROMATOGRAPHY;

ACEBUTOLOL; ALPRENOLOL; AMIDE; ATENOLOL; CORTICOSTERONE; CORTISONE; FENBUFEN; FENOPROFEN; FLURBIPROFEN; HYDROCORTISONE; HYDROCORTISONE ACETATE; IBUPROFEN; INDOPROFEN; LIDOCAINE; LIPOSOME; MEPIVACAINE; METOPROLOL; NADOLOL; NAPROXEN; OCTANOL; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; PINDOLOL; PREDNISOLONE; PREDNISONE; PRILOCAINE; PROPRANOLOL; SOTALOL; UNINDEXED DRUG; WATER;

ARTICLE; CHEMICAL MODIFICATION; DRUG RETENTION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOPHILICITY; PARTITION COEFFICIENT; PRIORITY JOURNAL;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPOSOMES; MODELS, CHEMICAL; OCTANOLS; ORGANIC CHEMICALS; PHOSPHATIDYLCHOLINES; WATER;

EID: 79551600405     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.12.105     Document Type: Article

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