Novel RPLC stationary phases for lipophilicity measurement: Solvatochromic analysis of retention mechanisms for neutral and basic compounds

Journal of Separation Science

Volumn 28, Issue 17, 2005, Pages 2350-2362

  Stella, Cinzia ^a   Galland, Alexandra ^a   Liu, Xiangli ^a   Testa, Bernard ^b   Rudaz, Serge ^a   Veuthey, Jean Luc ^a   Carrupt, Pierre Alain ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Basic compounds; Neutral compounds; Quantitative structure property relationships; RPLC

Indexed keywords

AGENTS; LIPIDS; PH EFFECTS; PHARMACODYNAMICS; PHARMACOKINETICS; STATISTICAL METHODS;

BASIC COMPOUNDS; LIPOPHILICITY; NEUTRAL COMPOUNDS; QUANTITATIVE STRUCTURE PROPERTY RELATIONSHIPS; RPLC; SOLVATOCHROMIC ANALYSIS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ARTICLE; CHEMICAL ANALYSIS; CLUSTER ANALYSIS; CORRELATION ANALYSIS; HUMAN; LIPOPHILICITY; METHODOLOGY; MULTIVARIATE ANALYSIS; PH; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLVATION;

CHROMATOGRAPHY, LIQUID; HYDROGEN-ION CONCENTRATION; LIPIDS; SOLUBILITY; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 28844504247     PISSN: 16159306     EISSN: None     Source Type: Journal    
DOI: 10.1002/jssc.200500104     Document Type: Article

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