Salubrinal protects cardiomyocytes against apoptosis in a rat myocardial infarction model via suppressing the dephosphorylation of eukaryotic translation initiation factor 2α

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 1043-1049

  Li, Rui Jun ^a   He, Kun Lun ^a   Li, Xin ^a   Wang, Li Li ^b   Liu, Chun Lei ^a   He, Yun Yun ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Apoptosis; Cardiomyocytes; Endoplasmic reticulum stress; Eukaryotic translation initiation factor 2 ; Myocardial infarction

Indexed keywords

CASPASE 12; CREATINE KINASE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; LACTATE DEHYDROGENASE; MESSENGER RNA; SALUBRINAL; SUPEROXIDE DISMUTASE; CARDIOTONIC AGENT; CINNAMIC ACID DERIVATIVE; DDIT3 PROTEIN, RAT; GRP78 PROTEIN, RAT; HEAT SHOCK PROTEIN; INITIATION FACTOR 2; THIOUREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; HEART; HEART INFARCTION; HEART INFARCTION SIZE; HEART PROTECTION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CARDIAC MUSCLE CELL; DISEASE EXACERBATION; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; WISTAR RAT;

EUKARYOTA; RATTUS;

ANIMALS; APOPTOSIS; CARDIOTONIC AGENTS; CASPASE 12; CINNAMATES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; MALE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; RATS; RATS, WISTAR; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; THIOUREA; TRANSCRIPTION FACTOR CHOP;

EID: 84926660144     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3508     Document Type: Article

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