Protective mechanism of Korean Red Ginseng in cisplatin-induced ototoxicity through attenuation of nuclear factor-κB and caspase-1 activation

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 315-322

  Kim, Su Jin ^a   Kwak, Hyun Jeong ^b   Kim, Dae Seung ^c   Choi, Hyun Myung ^b   Sim, Jung Eun ^b   Kim, Sung Hoon ^b   Um, Jae Young ^b   Hong, Seung Heon ^c  

^a Daegu Haany University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Wonkwang University   (South Korea)

Author keywords

Auditory cell; Caspase 1; Cisplatin; Korean Red Ginseng; Nuclear factor B

Indexed keywords

CISPLATIN; CYTOCHROME C; GINSENG EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT; CASPASE 3; PLANT EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUDITORY THRESHOLD; CELL DESTRUCTION; CONTROLLED STUDY; CORTI ORGAN; CYTOTOXICITY; ENZYME ACTIVATION; GINSENG; HAIR CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; OTOTOXICITY; RAT; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EVOKED BRAIN STEM AUDITORY RESPONSE; METABOLISM; MOUSE; PANAX; PATHOLOGY; SOUTH KOREA;

MUS; PANAX GINSENG; RATTUS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 1; CASPASE 3; CELL LINE; CISPLATIN; CYTOCHROMES C; ENZYME ACTIVATION; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; HAIR CELLS, AUDITORY; INTERLEUKIN-6; MALE; MICE; MICE, INBRED BALB C; NF-KAPPA B; ORGAN OF CORTI; PANAX; PLANT EXTRACTS; RATS; REACTIVE OXYGEN SPECIES; REPUBLIC OF KOREA;

EID: 84926651264     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3396     Document Type: Article

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