Cisplatin ototoxicity involves cytokines and STAT6 signaling network

Cell Research

Volumn 21, Issue 6, 2011, Pages 944-956

  Kim, Hyung Jin ^a   Oh, Gi Su ^a   Lee, Jeong Han ^a   Lyu, Ah Ra ^a   Ji, Hye Min ^a   Lee, Sang Heon ^a   Song, Jeho ^a   Park, Sung Joo ^b   You, Yong Ouk ^a   Sul, Jeong Dug ^c   Park, Channy ^d   Chung, Sang Young ^e   Moon, Sung Kyun ^f   Lim, David J ^f   So, Hong Seob ^a   Park, Raekil ^a  

^a Wonkwang University   (South Korea)

^b Wonkwang University   (South Korea)

^c Chung Ang University   (South Korea)

^d Nambu University   (South Korea)

^e Chonnam National University Medical School   (South Korea)

^f HOUSE EAR INSTITUTE   (United States)

Author keywords

apoptosis; cisplatin; inflammation; ototoxicity; STAT

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYTOKINE; CYTOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; STAT4 PROTEIN; STAT4 PROTEIN, MOUSE; STAT6 PROTEIN; STAT6 PROTEIN, MOUSE;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; COCHLEA; DRUG EFFECT; EVOKED BRAIN STEM AUDITORY RESPONSE; GENETIC TRANSCRIPTION; GENETICS; HAIR CELL; HEARING LOSS; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PROMOTER REGION; REPORTER GENE; RNA INTERFERENCE; SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CISPLATIN; COCHLEA; CYTOKINES; CYTOTOXINS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GENES, REPORTER; HAIR CELLS, AUDITORY; HEARING LOSS; LUCIFERASES; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STAT4 TRANSCRIPTION FACTOR; STAT6 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC;

MUS;

EID: 79960054388     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2011.27     Document Type: Article

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