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Volumn 46, Issue 2, 2011, Pages 148-155

Down-regulation of Bcl-2 is mediated by NF-κB activation in Helicobacter pylori-induced apoptosis of gastric epithelial cells

Author keywords

Apoptosis; Bcl 2; Helicobacter pylori; NF B

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

EID: 79951749918     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2010.525255     Document Type: Article
Times cited : (26)

References (43)
  • 1
    • 69449084254 scopus 로고    scopus 로고
    • Pathogenesis of Helicobacter pylori infection
    • Costa AC, Figueiredo C, Touati E. Pathogenesis of Helicobacter pylori infection. Helicobacter 2009;14(Suppl 1):15-20.
    • (2009) Helicobacter , vol.14 , Issue.1 , pp. 15-20
    • Costa, A.C.1    Figueiredo, C.2    Touati, E.3
  • 2
    • 70349211747 scopus 로고    scopus 로고
    • Coadaptation of helicobacter pylori and humans: Ancient history modern implications
    • Atherton JC, Blaser MJ. Coadaptation of Helicobacter pylori and humans: ancient history, modern implications. Clin Invest 2009;119:2475-87.
    • (2009) Clin. Invest , vol.119 , pp. 2475-2487
    • Atherton, J.C.1    Blaser, M.J.2
  • 5
    • 0029987967 scopus 로고    scopus 로고
    • Induction of gastric epithelial apoptosis by Helicobacter pylori
    • Moss SF, Calam J, Agarwal B, Wang S, Holt PR. Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut 1996; 38:498-501. (Pubitemid 26111366)
    • (1996) Gut , vol.38 , Issue.4 , pp. 498-501
    • Moss, S.F.1    Calam, J.2    Agarwal, B.3    Wang, S.4    Holt, P.R.5
  • 10
    • 0035430836 scopus 로고    scopus 로고
    • NF-κB, inducible nitric oxide synthase and apoptosis by Helicobacter pylori infection
    • DOI 10.1016/S0891-5849(01)00592-5, PII S0891584901005925
    • Lim JW, Kim H, Kim KH. NF-kB, inducible nitric oxide synthase and apoptosis by Helicobacter pylori infection. Free Rad Bio Med 2001;31:355-66. (Pubitemid 32675341)
    • (2001) Free Radical Biology and Medicine , vol.31 , Issue.3 , pp. 355-366
    • Lim, J.W.1    Kim, H.2    Kim, K.H.3
  • 11
    • 0028174061 scopus 로고
    • Function and activation of NF-kB in the immune system
    • Baeuerle PA, Henkel T. Function and activation of NF-kB in the immune system. Annu Rev Immunol 1994;12:141-79.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 12
    • 0028986193 scopus 로고
    • NF-kB: A lesson in family values
    • Thanos D, Maniatis T. NF-kB: a lesson in family values. Cell 1995;80:529-32.
    • (1995) Cell , vol.80 , pp. 529-532
    • Thanos, D.1    Maniatis, T.2
  • 13
    • 0027453548 scopus 로고
    • Promoter analysis of the gene encoding the IκB-α/MAD3 inhibitor of NF-κB: Positive regulation by members of the reI/NF-κB family
    • Le Bail O, Schmidt-Ullrich R, Israel A. Promoter analysis of the gene encoding the IkB-a/MAD3 inhibitor of NF-kB: positive regulation by members of the rel/NF-kB family. EMBO J 1993;12:5043-9. (Pubitemid 23358492)
    • (1993) EMBO Journal , vol.12 , Issue.13 , pp. 5043-5049
    • Le Bail, O.1    Schmidt-Ullrich, R.2    Israel, A.3
  • 14
    • 0028986075 scopus 로고
    • Control of IkBa proteolysis by site-specific signal-induced phosphorylation
    • Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U. Control of IkBa proteolysis by site-specific, signal-induced phosphorylation. Science 1995;267:1485-8.
    • (1995) Science , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 15
    • 0028978032 scopus 로고
    • Phosphorylation of human IkBa on serines 32 and 36 controls IkBa proteolysis and NF-kB activation in response to diverse stimuli
    • Traenckner EB, Pahl HL, Henkel T, Schmidt KN, Wilk S, Baeuerle PA. Phosphorylation of human IkBa on serines 32 and 36 controls IkBa proteolysis and NF-kB activation in response to diverse stimuli. EMBO J 1995;14:2876-83.
    • (1995) EMBO J. , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 16
    • 0035086794 scopus 로고    scopus 로고
    • Nuclear factor-κB regulates cyclooxyoenase-2 expression and cell proliferation in human gastric cancer cells
    • Lim JW, Kim H, Kim KH. Nuclear factor-kB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. Lab Invest 2001;81:349-60. (Pubitemid 32245067)
    • (2001) Laboratory Investigation , vol.81 , Issue.3 , pp. 349-360
    • Joo Weon Lim1    Kim, H.2    Kyung Hwan Kim3
  • 17
    • 0032844277 scopus 로고    scopus 로고
    • Effects of mannitol and dimethylthiourea on Helicobacter pylori-induced IL-8 production in gastric epithelial cells
    • DOI 10.1159/000028321
    • Kim H, Seo JY, Kim KH. Effects of mannitol and dimethylthiourea on Helicobacter pylori -induced IL-8- production in gastric epithelial cells. Pharmacology 1999; 59:201-11. (Pubitemid 29419602)
    • (1999) Pharmacology , vol.59 , Issue.4 , pp. 201-211
    • Kim, H.1    Seo, J.Y.2    Kim, K.H.3
  • 18
    • 0034070950 scopus 로고    scopus 로고
    • Inhibition of lipid peroxidation, NF-κB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells
    • DOI 10.1023/A:1005474013988
    • Kim H, Seo JY, Kim KH. Inhibition of lipid peroxidation, NF-kB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells. Dig Dis Sci 2000;45:621-8. (Pubitemid 30171942)
    • (2000) Digestive Diseases and Sciences , vol.45 , Issue.3 , pp. 621-628
    • Kim, H.1    Seo, J.Y.2    Kim, K.H.3
  • 20
    • 77049101945 scopus 로고    scopus 로고
    • Cell death mechanisms in the early stages of acute glutamate neurotoxicity
    • Kumar A, Singh RL, Babu GN. Cell death mechanisms in the early stages of acute glutamate neurotoxicity. Neurosci Res 2009;66(3):271-82.
    • (2009) Neurosci. Res. , vol.66 , Issue.3 , pp. 271-282
    • Kumar, A.1    Singh, R.L.2    Babu, G.N.3
  • 21
    • 0031046848 scopus 로고    scopus 로고
    • Apoptosis and disease: Regulation and clinical relevance of programmed cell death
    • DOI 10.1146/annurev.med.48.1.267
    • Rudin CM, Thompson CB. Apoptosis and disease: regulation and clinical relevance of programmed cell death. Annu Rev Med 1997;48:267-81. (Pubitemid 27101830)
    • (1997) Annual Review of Medicine , vol.48 , pp. 267-281
    • Rudin, C.M.1    Thompson, C.B.2
  • 23
    • 19244370521 scopus 로고    scopus 로고
    • Hypoxia-induced endothelial apoptosis through nuclear factor-κb (NF- κb)-mediated bcl-2 suppression: In vivo evidence of the importance of NF-κb in endothelial cell regulation
    • Matsushita H, Morishita R, Nata T, Aoki M, Nakagami H, Taniyama Y, et al. Hypoxia-induced endothelial apoptosis through nuclear factor-kB (NF-kB)-mediated bcl-2 suppression: in vivo evidence of the importance of NF-kB in endothelial cell regulation. Circ Res 2000;86: 974-81. (Pubitemid 30324310)
    • (2000) Circulation Research , vol.86 , Issue.9 , pp. 974-981
    • Matsushita, H.1    Morishita, R.2    Nata, T.3    Aoki, M.4    Nakagami, H.5    Taniyama, Y.6    Yamamoto, K.7    Higaki, J.8    Yasufumi, K.9    Ogihara, T.10
  • 26
    • 0035903124 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kB-mediated apoptosis induced by helicobacter pylori in gastric epithelial cells
    • Gupta RA, Polk DB, Krishna U, Israel DA, Yan F, DuBois RN, Peek RM. Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kB-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells. J Biol Chem 2001;276:31059-66.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31059-31066
    • Gupta, R.A.1    Polk, D.B.2    Krishna, U.3    Israel, D.A.4    Yan, F.5    DuBois, R.N.6    Peek, R.M.7
  • 27
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidine isothiocyanate-phenolchloroform extraction. Anal Biochem 1987;162:156-9. (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 28
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72: 248-54.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 29
    • 0036100766 scopus 로고    scopus 로고
    • Analysis of apoptotic and antiapoptotic signalling pathways induced by Helicobacter pylori
    • DOI 10.1136/gut.50.6.771
    • Maeda S, Yoshida H, Mitsuno Y, Hirata Y, Ogura K, Shiratori Y, Omata M. Analysis of apoptotic and antiapoptotic signaling pathways induced by Helicobacter pylori. Gut 2002;50:771-8. (Pubitemid 34539037)
    • (2002) Gut , vol.50 , Issue.6 , pp. 771-778
    • Maeda, S.1    Yoshida, H.2    Mitsuno, Y.3    Hirata, Y.4    Ogura, K.5    Shiratori, Y.6    Omata, M.7
  • 32
    • 1642380279 scopus 로고    scopus 로고
    • Helicobacter pylori Induces Plasminogen Activator Inhibitor 2 in Gastric Epithelial Cells through Nuclear Factor-κB and RhoA: Implications for Invasion and Apoptosis
    • DOI 10.1158/0008-5472.CAN-03-2399
    • Varro A, Noble PJ, Pritchard DM, Kennedy S, Hart CA, Dimaline R, Dockray GJ. Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-kB and RhoA: implications for invasion and apoptosis. Cancer Res 2004;64:1695-702. (Pubitemid 38428691)
    • (2004) Cancer Research , vol.64 , Issue.5 , pp. 1695-1702
    • Varro, A.1    Noble, P.-J.M.2    Pritchard, D.M.3    Kennedy, S.4    Hart, C.A.5    Dimaline, R.6    Dockray, G.J.7
  • 33
    • 11144300205 scopus 로고    scopus 로고
    • Protective mechanism of epigallocatechin-3-gallate against Helicobocter pylori-induced gastric epithelial cytotoxicity via the blockage of TLR-4 signaling
    • DOI 10.1111/j.1083-4389.2004.00281.x
    • Lee KM, Yeo M, Choue JS, Jin JH, Park SJ, Cheong JY, et al. Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori -induced gastric epithelial cytotoxicity via the blockage of TLR-4 signaling. Helicobacter 2004;9: 632-42. (Pubitemid 40023721)
    • (2004) Helicobacter , vol.9 , Issue.6 , pp. 632-642
    • Lee, K.-M.1    Yeo, M.2    Choue, J.-S.3    Jin, J.-H.4    Park, S.J.5    Cheong, J.-Y.6    Lee, K.J.7    Kim, J.-H.8    Hahm, K.-B.9
  • 34
    • 0030797727 scopus 로고    scopus 로고
    • Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death
    • DOI 10.1083/jcb.139.1.205
    • Miller TM, Moulder KL, Knudson CM, Creedon DJ, Deshmukh M, Korsmeyer SJ, Johnson EM. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J Biol Chem 1997;139:205-17. (Pubitemid 27444092)
    • (1997) Journal of Cell Biology , vol.139 , Issue.1 , pp. 205-217
    • Miller, T.M.1    Moulder, K.L.2    Knudson, C.M.3    Creedon, D.J.4    Deshmukh, M.5    Korsmeyer, S.J.6    Johnson Jr., E.M.7
  • 35
    • 0031453495 scopus 로고    scopus 로고
    • Expression of Bax and Bcl-2 protein in the gerbil hippocampus following transient forebrain ischemia and its modification by phencyclidine
    • Niwa M, Hara A, Iwai T, Sassa T, Mori H, Uematsu T. Expression of Bax and Bcl-2 protein in the gerbil hippocampus following transient forebrain ischemia and its modification by phencyclidine. Neurol Res 1997;19:629-33. (Pubitemid 28006647)
    • (1997) Neurological Research , vol.19 , Issue.6 , pp. 629-633
    • Niwa, M.1    Hara, A.2    Iwai, T.3    Sassa, T.4    Mori, H.5    Uematsu, T.6
  • 36
    • 0032409781 scopus 로고    scopus 로고
    • Bcl-2 family proteins
    • Reed JC. Bcl-2 family proteins. Oncogene 1998;17:3225-36. (Pubitemid 29043975)
    • (1998) Oncogene , vol.17 , Issue.25 , pp. 3225-3236
    • Reed, J.C.1
  • 37
    • 0035906546 scopus 로고    scopus 로고
    • Expression of Bax and Bcl-2 proteins during hypoxia in cerebral cortical neuronal nuclei of newborn piglets: Effect of administration of magnesium sulfate
    • DOI 10.1016/S0006-8993(01)02109-6, PII S0006899301021096
    • Ravishankar S, Ashraf QM, Fritz K, Mishra OP, Delivoria- Papadopoulos M. Expression of Bax and Bcl-2 proteins during hypoxia in cerebral cortical neuronal nuclei of newborn piglets: effect of administration of magnesium sulfate. Brain Res 2001;901:23-9. (Pubitemid 32718801)
    • (2001) Brain Research , vol.901 , Issue.1-2 , pp. 23-29
    • Ravishankar, S.1    Ashraf, Q.M.2    Fritz, K.3    Mishra, O.P.4    Delivoria-Papadopoulos, M.5
  • 38
    • 0028167599 scopus 로고
    • NF-kB activation of p53 a potential mechanism for suppressing cell growth in response to stress
    • Wu H, Lozano G. NF-kB activation of p53. A potential mechanism for suppressing cell growth in response to stress. J Biol Chem 1994;269:20067-74.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20067-20074
    • Wu, H.1    Lozano, G.2
  • 39
    • 0028032360 scopus 로고
    • Hypoxic activation of nuclear factor-κB is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2)
    • Koong AC, Chen EY, Mivechi NF, Denko NC, Stambrook P, Giaccia, AJ. Hypoxic activation of nuclear factor-kB is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2). Cancer Res 1994;54:5273-9. (Pubitemid 24336013)
    • (1994) Cancer Research , vol.54 , Issue.20 , pp. 5273-5279
    • Koong, A.C.1    Chen, E.Y.2    Mivechi, N.F.3    Denko, N.C.4    Stambrook, P.5    Giaccia, A.J.6
  • 40
    • 0028181243 scopus 로고
    • Autoregulation of the NF-kB transactivator RelA p65 by multiple cytoplasmic inhibitors containing ankyrin motifs
    • USA
    • Sun SC, Ganchi PA, Beraud C, Ballard DW, Greene WC. Autoregulation of the NF-kB transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proc Natl Acad Sci USA 1994;91:1346-50.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 1346-1350
    • Sun, S.C.1    Ganchi, P.A.2    Beraud, C.3    Ballard, D.W.4    Greene, W.C.5
  • 41
    • 0033596127 scopus 로고    scopus 로고
    • Control of apoptosis by Rel/NF-kB transcription factors
    • Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-kB transcription factors. Oncogene 1999;18:6910-24.
    • (1999) Oncogene , vol.18 , pp. 6910-6924
    • Barkett, M.1    Gilmore, T.D.2
  • 42
    • 0033561799 scopus 로고    scopus 로고
    • Nuclear factor κB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum
    • Qin ZH, Chen RW, Wang Y, Nakai M, Chuang DM, Chase TN. Nuclear factor kB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptormediated apoptosis in rat striatum. J Neurosci 1999;19: 4023-33. (Pubitemid 29222275)
    • (1999) Journal of Neuroscience , vol.19 , Issue.10 , pp. 4023-4033
    • Qin, Z.-H.1    Chen, R.-W.2    Wang, Y.3    Nakai, M.4    Chuang, D.-M.5    Chase, T.N.6


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