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Volumn 21, Issue 1, 2015, Pages 16-23

B Cells in Chronic Graft-versus-Host Disease

Author keywords

B cell; Chronic graft versus host disease; Stem cell transplantation

Indexed keywords

4 (4 CHLOROPHENYL) 2,3,9 TRIMETHYL 6H THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE 6 ACETIC ACID TERT BUTYL ESTER; B CELL ACTIVATING FACTOR; CORTICOSTEROID; CYCLOPHOSPHAMIDE; FOSTAMATINIB; IBRUTINIB; IMATINIB; IMMUNOGLOBULIN; KD 025; PREDNISONE; RHO KINASE INHIBITOR; RITUXIMAB; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG; B CELL ACTIVATING FACTOR RECEPTOR; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY; TNFRSF13C PROTEIN, HUMAN; TNFSF13B PROTEIN, HUMAN;

EID: 84926638546     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2014.10.029     Document Type: Review
Times cited : (75)

References (87)
  • 2
    • 84891851431 scopus 로고    scopus 로고
    • Uptake and use of recommendations for the diagnosis, severity scoring and management of chronic GVHD: an international survey of the EBMT-NCI Chronic GVHD Task Force
    • Duarte R.F., Greinix H., Rabin B., et al. Uptake and use of recommendations for the diagnosis, severity scoring and management of chronic GVHD: an international survey of the EBMT-NCI Chronic GVHD Task Force. Bone Marrow Transplant 2014, 49:49-54.
    • (2014) Bone Marrow Transplant , vol.49 , pp. 49-54
    • Duarte, R.F.1    Greinix, H.2    Rabin, B.3
  • 3
    • 84904470709 scopus 로고    scopus 로고
    • Current issues in chronic graft-versus-host disease
    • Socie G., Ritz J. Current issues in chronic graft-versus-host disease. Blood 2014, 124:374-384.
    • (2014) Blood , vol.124 , pp. 374-384
    • Socie, G.1    Ritz, J.2
  • 4
    • 20144386800 scopus 로고    scopus 로고
    • Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission
    • Miklos D.B., Kim H.T., Miller K.H., et al. Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission. Blood 2005, 105:2973-2978.
    • (2005) Blood , vol.105 , pp. 2973-2978
    • Miklos, D.B.1    Kim, H.T.2    Miller, K.H.3
  • 5
    • 65549132114 scopus 로고    scopus 로고
    • Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease
    • Sarantopoulos S., Stevenson K.E., Kim H.T., et al. Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease. Blood 2009, 113:3865-3874.
    • (2009) Blood , vol.113 , pp. 3865-3874
    • Sarantopoulos, S.1    Stevenson, K.E.2    Kim, H.T.3
  • 6
    • 84856908923 scopus 로고    scopus 로고
    • Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans
    • Srinivasan M., Flynn R., Price A., et al. Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans. Blood 2012, 119:1570-1580.
    • (2012) Blood , vol.119 , pp. 1570-1580
    • Srinivasan, M.1    Flynn, R.2    Price, A.3
  • 7
    • 80052938004 scopus 로고    scopus 로고
    • Rituximab for prevention and treatment of graft-versus-host disease
    • Kharfan-Dabaja M.A., Cutler C.S. Rituximab for prevention and treatment of graft-versus-host disease. Int J Hematol 2011, 93:578-585.
    • (2011) Int J Hematol , vol.93 , pp. 578-585
    • Kharfan-Dabaja, M.A.1    Cutler, C.S.2
  • 8
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • Wardemann H., Yurasov S., Schaefer A., et al. Predominant autoantibody production by early human B cell precursors. Science 2003, 301:1374-1377.
    • (2003) Science , vol.301 , pp. 1374-1377
    • Wardemann, H.1    Yurasov, S.2    Schaefer, A.3
  • 9
    • 0029556119 scopus 로고
    • Does immunological tolerance explain the waste in the B-lymphocyte immune system? Experiment and theory
    • Nemazee D. Does immunological tolerance explain the waste in the B-lymphocyte immune system? Experiment and theory. Ann N Y Acad Sci 1995, 764:397-401.
    • (1995) Ann N Y Acad Sci , vol.764 , pp. 397-401
    • Nemazee, D.1
  • 10
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: deleting and tuninglymphocyte repertoires
    • Goodnow C.C. Balancing immunity and tolerance: deleting and tuninglymphocyte repertoires. Proc Natl Acad Sci U S A 1996, 93:2264-2271.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2264-2271
    • Goodnow, C.C.1
  • 11
    • 0034278588 scopus 로고    scopus 로고
    • Circulating human B cells that express surrogate light chains and edited receptors
    • Meffre E., Davis E., Schiff C., et al. Circulating human B cells that express surrogate light chains and edited receptors. Nat Immunol 2000, 1:207-213.
    • (2000) Nat Immunol , vol.1 , pp. 207-213
    • Meffre, E.1    Davis, E.2    Schiff, C.3
  • 12
    • 15444365480 scopus 로고    scopus 로고
    • Defective B cell tolerance checkpoints in systemic lupus erythematosus
    • Yurasov S., Wardemann H., Hammersen J., et al. Defective B cell tolerance checkpoints in systemic lupus erythematosus. JExp Med 2005, 201:703-711.
    • (2005) JExp Med , vol.201 , pp. 703-711
    • Yurasov, S.1    Wardemann, H.2    Hammersen, J.3
  • 13
    • 0942268734 scopus 로고    scopus 로고
    • Peripheral B-cell maturation: the intersection of selection and homeostasis
    • Cancro M.P. Peripheral B-cell maturation: the intersection of selection and homeostasis. Immunol Rev 2004, 197:89-101.
    • (2004) Immunol Rev , vol.197 , pp. 89-101
    • Cancro, M.P.1
  • 14
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive Bcells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • Thien M., Phan T.G., Gardam S., et al. Excess BAFF rescues self-reactive Bcells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 2004, 20:785-798.
    • (2004) Immunity , vol.20 , pp. 785-798
    • Thien, M.1    Phan, T.G.2    Gardam, S.3
  • 15
    • 1842633887 scopus 로고    scopus 로고
    • Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
    • Lesley R., Xu Y., Kalled S.L., et al. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity 2004, 20:441-453.
    • (2004) Immunity , vol.20 , pp. 441-453
    • Lesley, R.1    Xu, Y.2    Kalled, S.L.3
  • 16
    • 84921477151 scopus 로고    scopus 로고
    • High-throughput immunoglobulin heavy chain variable region repertoire analysis of CD27+ B cell subsets from patients with chronic GVHD
    • [ASH Annual Meeting Abstracts]
    • Tata P.V., Vincent B.G., Kuan P.F., et al. High-throughput immunoglobulin heavy chain variable region repertoire analysis of CD27+ B cell subsets from patients with chronic GVHD. Blood 2013, 122:2055. [ASH Annual Meeting Abstracts].
    • (2013) Blood , vol.122 , pp. 2055
    • Tata, P.V.1    Vincent, B.G.2    Kuan, P.F.3
  • 17
    • 33644926381 scopus 로고    scopus 로고
    • The development of autoantibodies after allogeneic stem cell transplantation is related with chronic graft-vs-host disease and immune recovery
    • Patriarca F., Skert C., Sperotto A., et al. The development of autoantibodies after allogeneic stem cell transplantation is related with chronic graft-vs-host disease and immune recovery. Exp Hematol 2006, 34:389-396.
    • (2006) Exp Hematol , vol.34 , pp. 389-396
    • Patriarca, F.1    Skert, C.2    Sperotto, A.3
  • 18
    • 34347386226 scopus 로고    scopus 로고
    • Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease
    • Svegliati S., Olivieri A., Campelli N., et al. Stimulatory autoantibodies to PDGF receptor in patients with extensive chronic graft-versus-host disease. Blood 2007, 110:237-241.
    • (2007) Blood , vol.110 , pp. 237-241
    • Svegliati, S.1    Olivieri, A.2    Campelli, N.3
  • 19
    • 0025075980 scopus 로고
    • Autoantibodies in chronic GVHD: high prevalence of antinucleolar antibodies
    • Kier P., Penner E., Bakos S., et al. Autoantibodies in chronic GVHD: high prevalence of antinucleolar antibodies. Bone Marrow Transplant 1990, 6:93-96.
    • (1990) Bone Marrow Transplant , vol.6 , pp. 93-96
    • Kier, P.1    Penner, E.2    Bakos, S.3
  • 20
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster J.G., Hartley S.B., Goodnow C.C. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 1994, 371:389-395.
    • (1994) Nature , vol.371 , pp. 389-395
    • Cyster, J.G.1    Hartley, S.B.2    Goodnow, C.C.3
  • 21
    • 84897960209 scopus 로고    scopus 로고
    • Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease
    • Jacobson C.A., Sun L., Kim H.T., et al. Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease. Biol Blood Marrow Transplant 2014, 20:668-675.
    • (2014) Biol Blood Marrow Transplant , vol.20 , pp. 668-675
    • Jacobson, C.A.1    Sun, L.2    Kim, H.T.3
  • 22
    • 84860805172 scopus 로고    scopus 로고
    • Bone marrow B cell precursor number after allogeneic stem cell transplantation and GVHD development
    • Fedoriw Y., Samulski T.D., Deal A.M., et al. Bone marrow B cell precursor number after allogeneic stem cell transplantation and GVHD development. Biol Blood Marrow Transplant 2012, 18:968-973.
    • (2012) Biol Blood Marrow Transplant , vol.18 , pp. 968-973
    • Fedoriw, Y.1    Samulski, T.D.2    Deal, A.M.3
  • 23
    • 35948938957 scopus 로고    scopus 로고
    • High levels of B-cell activating factor in patients with active chronic graft-versus-host disease
    • Sarantopoulos S., Stevenson K.E., Kim H.T., et al. High levels of B-cell activating factor in patients with active chronic graft-versus-host disease. Clin Cancer Res 2007, 13:6107-6114.
    • (2007) Clin Cancer Res , vol.13 , pp. 6107-6114
    • Sarantopoulos, S.1    Stevenson, K.E.2    Kim, H.T.3
  • 24
    • 0029664331 scopus 로고    scopus 로고
    • Lack of B cells precursors in marrow transplant recipients with chronic graft-versus-host disease
    • Storek J., Witherspoon R.P., Webb D., Storb R. Lack of B cells precursors in marrow transplant recipients with chronic graft-versus-host disease. Am J Hematol 1996, 52:82-89.
    • (1996) Am J Hematol , vol.52 , pp. 82-89
    • Storek, J.1    Witherspoon, R.P.2    Webb, D.3    Storb, R.4
  • 25
    • 84907652276 scopus 로고    scopus 로고
    • Impact of acute and chronic graft-versus-host disease on human B-cell generation and replication
    • Glauzy S., Soret J., Fournier I., et al. Impact of acute and chronic graft-versus-host disease on human B-cell generation and replication. Blood 2014, 124:2459-2462.
    • (2014) Blood , vol.124 , pp. 2459-2462
    • Glauzy, S.1    Soret, J.2    Fournier, I.3
  • 26
    • 84879154724 scopus 로고    scopus 로고
    • Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease
    • Le Huu D., Matsushita T., Jin G., et al. Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease. Blood 2013, 121:3274-3283.
    • (2013) Blood , vol.121 , pp. 3274-3283
    • Le Huu, D.1    Matsushita, T.2    Jin, G.3
  • 27
    • 84907272636 scopus 로고    scopus 로고
    • Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD
    • Khoder A., Sarvaria A., Alsuliman A., et al. Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD. Blood 2014, 124:2034-2045.
    • (2014) Blood , vol.124 , pp. 2034-2045
    • Khoder, A.1    Sarvaria, A.2    Alsuliman, A.3
  • 28
    • 79951830638 scopus 로고    scopus 로고
    • Recovery of B-cell homeostasisafter rituximab in chronic graft-versus-host disease
    • Sarantopoulos S., Stevenson K.E., Kim H.T., et al. Recovery of B-cell homeostasisafter rituximab in chronic graft-versus-host disease. Blood 2011, 117:2275-2283.
    • (2011) Blood , vol.117 , pp. 2275-2283
    • Sarantopoulos, S.1    Stevenson, K.E.2    Kim, H.T.3
  • 29
    • 84921498948 scopus 로고    scopus 로고
    • Bcells from patients with chronic GVHD signal via the AKT-driven survival and metabolic fitness pathway
    • [BMT Tandem Meeting Abstracts]
    • Allen J.L., Wooten J., Fore M., et al. Bcells from patients with chronic GVHD signal via the AKT-driven survival and metabolic fitness pathway. Biol Blood Marrow Transplant 2012, 18:S208. [BMT Tandem Meeting Abstracts].
    • (2012) Biol Blood Marrow Transplant , vol.18 , pp. S208
    • Allen, J.L.1    Wooten, J.2    Fore, M.3
  • 30
    • 33645086656 scopus 로고    scopus 로고
    • Loss of the proapoptotic protein, Bim, breaks B cell anergy
    • Oliver P.M., Vass T., Kappler J., Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. JExp Med 2006, 203:731-741.
    • (2006) JExp Med , vol.203 , pp. 731-741
    • Oliver, P.M.1    Vass, T.2    Kappler, J.3    Marrack, P.4
  • 31
    • 0141959215 scopus 로고    scopus 로고
    • Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
    • Enders A., Bouillet P., Puthalakath H., et al. Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells. JExp Med 2003, 198:1119-1126.
    • (2003) JExp Med , vol.198 , pp. 1119-1126
    • Enders, A.1    Bouillet, P.2    Puthalakath, H.3
  • 32
    • 84866603654 scopus 로고    scopus 로고
    • Bcells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways
    • Allen J.L., Fore M.S., Wooten J., et al. Bcells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways. Blood 2012, 120:2529-2536.
    • (2012) Blood , vol.120 , pp. 2529-2536
    • Allen, J.L.1    Fore, M.S.2    Wooten, J.3
  • 33
    • 84898606445 scopus 로고    scopus 로고
    • Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells
    • Caro-Maldonado A., Wang R., Nichols A.G., et al. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. JImmunol 2014, 192:3626-3636.
    • (2014) JImmunol , vol.192 , pp. 3626-3636
    • Caro-Maldonado, A.1    Wang, R.2    Nichols, A.G.3
  • 34
    • 70249086961 scopus 로고    scopus 로고
    • Signalling crosstalk in B cells: managing worth and need
    • Cancro M.P. Signalling crosstalk in B cells: managing worth and need. Nat Rev Immunol 2009, 9:657-661.
    • (2009) Nat Rev Immunol , vol.9 , pp. 657-661
    • Cancro, M.P.1
  • 35
    • 33750524262 scopus 로고    scopus 로고
    • BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism
    • Patke A., Mecklenbrauker I., Erdjument-Bromage H., et al. BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism. JExp Med 2006, 203:2551-2562.
    • (2006) JExp Med , vol.203 , pp. 2551-2562
    • Patke, A.1    Mecklenbrauker, I.2    Erdjument-Bromage, H.3
  • 36
    • 84897483138 scopus 로고    scopus 로고
    • Increased BCR responsiveness in B cells from patients with chronic GVHD
    • Allen J.L., Tata P.V., Fore M.S., et al. Increased BCR responsiveness in B cells from patients with chronic GVHD. Blood 2014, 123:2108-2115.
    • (2014) Blood , vol.123 , pp. 2108-2115
    • Allen, J.L.1    Tata, P.V.2    Fore, M.S.3
  • 37
    • 0035827623 scopus 로고    scopus 로고
    • The adaptor protein BLNK is required for b cell antigen receptor-induced activation of nuclear factor-kappa B and cell cycle entry and survival of B lymphocytes
    • Tan J.E., Wong S.C., Gan S.K., et al. The adaptor protein BLNK is required for b cell antigen receptor-induced activation of nuclear factor-kappa B and cell cycle entry and survival of B lymphocytes. JBiol Chem 2001, 276:20055-20063.
    • (2001) JBiol Chem , vol.276 , pp. 20055-20063
    • Tan, J.E.1    Wong, S.C.2    Gan, S.K.3
  • 38
    • 66549095183 scopus 로고    scopus 로고
    • BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells
    • Fu L., Lin-Lee Y.C., Pham L.V., et al. BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells. Blood 2009, 113:4627-4636.
    • (2009) Blood , vol.113 , pp. 4627-4636
    • Fu, L.1    Lin-Lee, Y.C.2    Pham, L.V.3
  • 39
    • 20444362731 scopus 로고    scopus 로고
    • Emergent autoimmunity in graft-versus-host disease
    • Tivol E., Komorowski R., Drobyski W.R. Emergent autoimmunity in graft-versus-host disease. Blood 2005, 105:4885-4891.
    • (2005) Blood , vol.105 , pp. 4885-4891
    • Tivol, E.1    Komorowski, R.2    Drobyski, W.R.3
  • 40
    • 84862888262 scopus 로고    scopus 로고
    • Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease
    • Young J.S., Wu T., Chen Y., et al. Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease. JImmunol 2012, 189:222-233.
    • (2012) JImmunol , vol.189 , pp. 222-233
    • Young, J.S.1    Wu, T.2    Chen, Y.3
  • 41
    • 79251551077 scopus 로고    scopus 로고
    • Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease
    • Zhao D., Young J.S., Chen Y.H., et al. Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease. JImmunol 2011, 186:856-868.
    • (2011) JImmunol , vol.186 , pp. 856-868
    • Zhao, D.1    Young, J.S.2    Chen, Y.H.3
  • 42
    • 2442534666 scopus 로고    scopus 로고
    • Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation
    • Zorn E., Miklos D.B., Floyd B.H., et al. Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation. JExp Med 2004, 199:1133-1142.
    • (2004) JExp Med , vol.199 , pp. 1133-1142
    • Zorn, E.1    Miklos, D.B.2    Floyd, B.H.3
  • 43
    • 79961021737 scopus 로고    scopus 로고
    • Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation
    • Porcheray F., Miklos D.B., Floyd B.H., et al. Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation. Transplantation 2011, 92:359-365.
    • (2011) Transplantation , vol.92 , pp. 359-365
    • Porcheray, F.1    Miklos, D.B.2    Floyd, B.H.3
  • 44
    • 0037097033 scopus 로고    scopus 로고
    • Endothelial injury mediated by cytotoxic T lymphocytes and loss of microvessels in chronic graft versus host disease
    • Biedermann B.C., Sahner S., Gregor M., et al. Endothelial injury mediated by cytotoxic T lymphocytes and loss of microvessels in chronic graft versus host disease. Lancet 2002, 359:2078-2083.
    • (2002) Lancet , vol.359 , pp. 2078-2083
    • Biedermann, B.C.1    Sahner, S.2    Gregor, M.3
  • 45
    • 0035004320 scopus 로고    scopus 로고
    • Regulation of the T-independent humoral response by TACI
    • von Bulow G.U., van Deursen J.M., Bram R.J. Regulation of the T-independent humoral response by TACI. Immunity 2001, 14:573-582.
    • (2001) Immunity , vol.14 , pp. 573-582
    • von Bulow, G.U.1    van Deursen, J.M.2    Bram, R.J.3
  • 46
    • 17844363748 scopus 로고    scopus 로고
    • Blymphocytes participate in cross-presentation of antigen following gene gun vaccination
    • Hon H., Oran A., Brocker T., Jacob J. Blymphocytes participate in cross-presentation of antigen following gene gun vaccination. JImmunol 2005, 174:5233-5242.
    • (2005) JImmunol , vol.174 , pp. 5233-5242
    • Hon, H.1    Oran, A.2    Brocker, T.3    Jacob, J.4
  • 47
    • 0018098193 scopus 로고
    • Deposition of IgM and complement at the dermoepidermal junction in acute and chronic cutaneous graft-vs-host disease in man
    • Tsoi M.S., Storb R., Jones E., et al. Deposition of IgM and complement at the dermoepidermal junction in acute and chronic cutaneous graft-vs-host disease in man. JImmunol 1978, 120:1485-1492.
    • (1978) JImmunol , vol.120 , pp. 1485-1492
    • Tsoi, M.S.1    Storb, R.2    Jones, E.3
  • 48
    • 18144365892 scopus 로고    scopus 로고
    • Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells
    • Groh V., Li Y.Q., Cioca D., et al. Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells. Proc Natl Acad Sci U S A 2005, 102:6461-6466.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 6461-6466
    • Groh, V.1    Li, Y.Q.2    Cioca, D.3
  • 49
    • 0037033367 scopus 로고    scopus 로고
    • Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells
    • Kita H., Lian Z.X., Van de Water J., et al. Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells. JExp Med 2002, 195:113-123.
    • (2002) JExp Med , vol.195 , pp. 113-123
    • Kita, H.1    Lian, Z.X.2    Van de Water, J.3
  • 50
    • 0036307752 scopus 로고    scopus 로고
    • Immune complex-mediated antigen presentation induces tumor immunity
    • Rafiq K., Bergtold A., Clynes R. Immune complex-mediated antigen presentation induces tumor immunity. JClin Invest 2002, 110:71-79.
    • (2002) JClin Invest , vol.110 , pp. 71-79
    • Rafiq, K.1    Bergtold, A.2    Clynes, R.3
  • 51
    • 74849138095 scopus 로고    scopus 로고
    • Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
    • Simpson N., Gatenby P.A., Wilson A., et al. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum 2010, 62:234-244.
    • (2010) Arthritis Rheum , vol.62 , pp. 234-244
    • Simpson, N.1    Gatenby, P.A.2    Wilson, A.3
  • 52
    • 84859726737 scopus 로고    scopus 로고
    • Tcells that promote B-Cell maturation in systemic autoimmunity
    • Weinstein J.S., Hernandez S.G., Craft J. Tcells that promote B-Cell maturation in systemic autoimmunity. Immunol Rev 2012, 247:160-171.
    • (2012) Immunol Rev , vol.247 , pp. 160-171
    • Weinstein, J.S.1    Hernandez, S.G.2    Craft, J.3
  • 53
    • 84902668500 scopus 로고    scopus 로고
    • Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans
    • Flynn R., Du J., Veenstra R.G., et al. Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood 2014, 123:3988-3998.
    • (2014) Blood , vol.123 , pp. 3988-3998
    • Flynn, R.1    Du, J.2    Veenstra, R.G.3
  • 54
    • 33748671153 scopus 로고    scopus 로고
    • BLyS receptor signatures resolve homeostatically independent compartments among naive and antigen-experienced B cells
    • Treml L.S., Crowley J.E., Cancro M.P. BLyS receptor signatures resolve homeostatically independent compartments among naive and antigen-experienced B cells. Semin Immunol 2006, 18:297-304.
    • (2006) Semin Immunol , vol.18 , pp. 297-304
    • Treml, L.S.1    Crowley, J.E.2    Cancro, M.P.3
  • 55
    • 33747838476 scopus 로고    scopus 로고
    • Regulation of B cell self-tolerance by BAFF
    • Brink R. Regulation of B cell self-tolerance by BAFF. Semin Immunol 2006, 18:276-283.
    • (2006) Semin Immunol , vol.18 , pp. 276-283
    • Brink, R.1
  • 56
    • 34848879797 scopus 로고    scopus 로고
    • Anew murine model for bronchiolitis obliterans post-bone marrow transplant
    • Panoskaltsis-Mortari A., Tram K.V., Price A.P., et al. Anew murine model for bronchiolitis obliterans post-bone marrow transplant. Am J Respir Crit Care Med 2007, 176:713-723.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 713-723
    • Panoskaltsis-Mortari, A.1    Tram, K.V.2    Price, A.P.3
  • 57
    • 84886855920 scopus 로고    scopus 로고
    • Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial
    • Cutler C., Kim H.T., Bindra B., et al. Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial. Blood 2013, 122:1510-1517.
    • (2013) Blood , vol.122 , pp. 1510-1517
    • Cutler, C.1    Kim, H.T.2    Bindra, B.3
  • 58
    • 84903991044 scopus 로고    scopus 로고
    • Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects
    • Johnston H.F., Xu Y., Racine J.J., et al. Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects. Biol Blood Marrow Transplant 2014, 20:1089-1103.
    • (2014) Biol Blood Marrow Transplant , vol.20 , pp. 1089-1103
    • Johnston, H.F.1    Xu, Y.2    Racine, J.J.3
  • 59
    • 84879209826 scopus 로고    scopus 로고
    • New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes
    • Bunting K.L., Melnick A.M. New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes. Curr Opin Immunol 2013, 25:339-346.
    • (2013) Curr Opin Immunol , vol.25 , pp. 339-346
    • Bunting, K.L.1    Melnick, A.M.2
  • 60
    • 84878972552 scopus 로고    scopus 로고
    • The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
    • Floyd S.R., Pacold M.E., Huang Q., et al. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. Nature 2013, 498:246-250.
    • (2013) Nature , vol.498 , pp. 246-250
    • Floyd, S.R.1    Pacold, M.E.2    Huang, Q.3
  • 61
    • 65349119454 scopus 로고    scopus 로고
    • Apeptomimetic inhibitor of BCL6 with potent antilymphoma effects invitro and invivo
    • Cerchietti L.C., Yang S.N., Shaknovich R., et al. Apeptomimetic inhibitor of BCL6 with potent antilymphoma effects invitro and invivo. Blood 2009, 113:3397-3405.
    • (2009) Blood , vol.113 , pp. 3397-3405
    • Cerchietti, L.C.1    Yang, S.N.2    Shaknovich, R.3
  • 62
    • 77953494012 scopus 로고    scopus 로고
    • BCL6 is critical for the development of a diverse primary B cell repertoire
    • Duy C., Yu J.J., Nahar R., et al. BCL6 is critical for the development of a diverse primary B cell repertoire. JExp Med 2010, 207:1209-1221.
    • (2010) JExp Med , vol.207 , pp. 1209-1221
    • Duy, C.1    Yu, J.J.2    Nahar, R.3
  • 63
    • 84879750981 scopus 로고    scopus 로고
    • An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1
    • Konze K.D., Ma A., Li F., et al. An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1. ACS Chem Biol 2013, 8:1324-1334.
    • (2013) ACS Chem Biol , vol.8 , pp. 1324-1334
    • Konze, K.D.1    Ma, A.2    Li, F.3
  • 64
    • 84863012446 scopus 로고    scopus 로고
    • Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells
    • He S., Wang J., Kato K., et al. Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells. Blood 2012, 119:1274-1282.
    • (2012) Blood , vol.119 , pp. 1274-1282
    • He, S.1    Wang, J.2    Kato, K.3
  • 65
    • 78650847770 scopus 로고    scopus 로고
    • Selective inhibition of BET bromodomains
    • Filippakopoulos P., Qi J., Picaud S., et al. Selective inhibition of BET bromodomains. Nature 2010, 468:1067-1073.
    • (2010) Nature , vol.468 , pp. 1067-1073
    • Filippakopoulos, P.1    Qi, J.2    Picaud, S.3
  • 66
    • 84859715609 scopus 로고    scopus 로고
    • Roles of BCL6 in normal and transformed germinal center B cells
    • Basso K., Dalla-Favera R. Roles of BCL6 in normal and transformed germinal center B cells. Immunol Rev 2012, 247:172-183.
    • (2012) Immunol Rev , vol.247 , pp. 172-183
    • Basso, K.1    Dalla-Favera, R.2
  • 67
    • 67049097382 scopus 로고    scopus 로고
    • The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL
    • Ci W., Polo J.M., Cerchietti L., et al. The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL. Blood 2009, 113:5536-5548.
    • (2009) Blood , vol.113 , pp. 5536-5548
    • Ci, W.1    Polo, J.M.2    Cerchietti, L.3
  • 68
    • 55049134780 scopus 로고    scopus 로고
    • Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin
    • Boerma M., Fu Q., Wang J., et al. Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin. Blood Coagul Fibrinolysis 2008, 19:709-718.
    • (2008) Blood Coagul Fibrinolysis , vol.19 , pp. 709-718
    • Boerma, M.1    Fu, Q.2    Wang, J.3
  • 69
    • 84913580141 scopus 로고    scopus 로고
    • Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells
    • Zanin-Zhorov A., Mo R., Scher J., et al. Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells. Proc Natl Acad Sci U S A 2014, 10.1073/pnas.1414189111.
    • (2014) Proc Natl Acad Sci U S A
    • Zanin-Zhorov, A.1    Mo, R.2    Scher, J.3
  • 71
    • 0033945186 scopus 로고    scopus 로고
    • The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective
    • Satterthwaite A.B., Witte O.N. The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective. Immunol Rev 2000, 175:120-127.
    • (2000) Immunol Rev , vol.175 , pp. 120-127
    • Satterthwaite, A.B.1    Witte, O.N.2
  • 72
    • 79960133279 scopus 로고    scopus 로고
    • The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
    • Chang B.Y., Huang M.M., Francesco M., et al. The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells. Arthritis Res Ther 2011, 13:R115.
    • (2011) Arthritis Res Ther , vol.13 , pp. R115
    • Chang, B.Y.1    Huang, M.M.2    Francesco, M.3
  • 73
    • 79959404661 scopus 로고    scopus 로고
    • Bruton tyrosine kinase representsa promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
    • Herman S.E., Gordon A.L., Hertlein E., et al. Bruton tyrosine kinase representsa promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765. Blood 2011, 117:6287-6296.
    • (2011) Blood , vol.117 , pp. 6287-6296
    • Herman, S.E.1    Gordon, A.L.2    Hertlein, E.3
  • 74
    • 84888216911 scopus 로고    scopus 로고
    • Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1 selective pressure in T-lymphocytes
    • Dubovsky J.A., Beckwith K.A., Natarajan G., et al. Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1 selective pressure in T-lymphocytes. Blood 2013, 122:2539-2549.
    • (2013) Blood , vol.122 , pp. 2539-2549
    • Dubovsky, J.A.1    Beckwith, K.A.2    Natarajan, G.3
  • 75
    • 0020521723 scopus 로고
    • Acute and chronic graft-versus-host disease induced by minor histocompatibility antigens in mice
    • Hamilton B.L., Parkman R. Acute and chronic graft-versus-host disease induced by minor histocompatibility antigens in mice. Transplantation 1983, 36:150-155.
    • (1983) Transplantation , vol.36 , pp. 150-155
    • Hamilton, B.L.1    Parkman, R.2
  • 76
    • 78650294662 scopus 로고    scopus 로고
    • An oral Syk kinase inhibitor in the treatment of rheumatoid arthritis: a three-month randomized, placebo-controlled, phase II study in patients with active rheumatoid arthritis that did not respond to biologic agents
    • Genovese M.C., Kavanaugh A., Weinblatt M.E., et al. An oral Syk kinase inhibitor in the treatment of rheumatoid arthritis: a three-month randomized, placebo-controlled, phase II study in patients with active rheumatoid arthritis that did not respond to biologic agents. Arthritis Rheum 2011, 63:337-345.
    • (2011) Arthritis Rheum , vol.63 , pp. 337-345
    • Genovese, M.C.1    Kavanaugh, A.2    Weinblatt, M.E.3
  • 77
    • 55849114400 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial
    • Weinblatt M.E., Kavanaugh A., Burgos-Vargas R., et al. Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial. Arthritis Rheum 2008, 58:3309-3318.
    • (2008) Arthritis Rheum , vol.58 , pp. 3309-3318
    • Weinblatt, M.E.1    Kavanaugh, A.2    Burgos-Vargas, R.3
  • 78
    • 0034662901 scopus 로고    scopus 로고
    • Anti-CD20 chimeric monoclonal antibody treatment of refractory immune-mediated thrombocytopenia in a patient with chronic graft-versus-host disease
    • Ratanatharathorn V., Carson E., Reynolds C., et al. Anti-CD20 chimeric monoclonal antibody treatment of refractory immune-mediated thrombocytopenia in a patient with chronic graft-versus-host disease. Ann Intern Med 2000, 133:275-279.
    • (2000) Ann Intern Med , vol.133 , pp. 275-279
    • Ratanatharathorn, V.1    Carson, E.2    Reynolds, C.3
  • 79
    • 9144219634 scopus 로고    scopus 로고
    • Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors
    • Miklos D.B., Kim H.T., Zorn E., et al. Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors. Blood 2004, 103:353-359.
    • (2004) Blood , vol.103 , pp. 353-359
    • Miklos, D.B.1    Kim, H.T.2    Zorn, E.3
  • 80
    • 33745964855 scopus 로고    scopus 로고
    • Rituximab for steroid-refractory chronic graft-versus-host disease
    • Cutler C., Miklos D., Kim H.T., et al. Rituximab for steroid-refractory chronic graft-versus-host disease. Blood 2006, 108:756-762.
    • (2006) Blood , vol.108 , pp. 756-762
    • Cutler, C.1    Miklos, D.2    Kim, H.T.3
  • 81
    • 67849108291 scopus 로고    scopus 로고
    • Efficacy of rituximab in the setting of steroid-refractory chronic graft-versus-host disease: a systematic review and meta-analysis
    • Kharfan-Dabaja M.A., Mhaskar A.R., Djulbegovic B., et al. Efficacy of rituximab in the setting of steroid-refractory chronic graft-versus-host disease: a systematic review and meta-analysis. Biol Blood Marrow Transplant 2009, 15:1005-1013.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 1005-1013
    • Kharfan-Dabaja, M.A.1    Mhaskar, A.R.2    Djulbegovic, B.3
  • 82
    • 33644984521 scopus 로고    scopus 로고
    • Rituximab is effective for steroid-refractory sclerodermatous chronic graft-versus-host disease
    • Okamoto M., Okano A., Akamatsu S., et al. Rituximab is effective for steroid-refractory sclerodermatous chronic graft-versus-host disease. Leukemia 2006, 20:172-173.
    • (2006) Leukemia , vol.20 , pp. 172-173
    • Okamoto, M.1    Okano, A.2    Akamatsu, S.3
  • 83
    • 84921495607 scopus 로고    scopus 로고
    • Rituximab provides steroid-sparing therapy in new-onset chronic graft-versus-host disease
    • [BMT TandemMeeting Abstracts]
    • Sahaf B., Arai S., Otani J., et al. Rituximab provides steroid-sparing therapy in new-onset chronic graft-versus-host disease. Biol Blood Marrow Transplant 2013, 19:S140. [BMT TandemMeeting Abstracts].
    • (2013) Biol Blood Marrow Transplant , vol.19 , pp. S140
    • Sahaf, B.1    Arai, S.2    Otani, J.3
  • 84
    • 84862744899 scopus 로고    scopus 로고
    • Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence
    • Arai S., Sahaf B., Narasimhan B., et al. Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence. Blood 2012, 119:6145-6154.
    • (2012) Blood , vol.119 , pp. 6145-6154
    • Arai, S.1    Sahaf, B.2    Narasimhan, B.3
  • 85
    • 70349246939 scopus 로고    scopus 로고
    • TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors
    • Kohrt H.E., Turnbull B.B., Heydari K., et al. TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors. Blood 2009, 114:1099-1109.
    • (2009) Blood , vol.114 , pp. 1099-1109
    • Kohrt, H.E.1    Turnbull, B.B.2    Heydari, K.3
  • 86
    • 77953244782 scopus 로고    scopus 로고
    • Rituximab for graft-versus-host-disease prophylaxis after allogeneic stem cell transplantation given as treatment of high risk relapse of aggressive lymphoma: results of a randomized phase II study
    • [ASH Annual Meeting Abstracts]
    • Glass B., Hasenkamp J., Gorlitz A., et al. Rituximab for graft-versus-host-disease prophylaxis after allogeneic stem cell transplantation given as treatment of high risk relapse of aggressive lymphoma: results of a randomized phase II study. Blood 2008, 112:1974. [ASH Annual Meeting Abstracts].
    • (2008) Blood , vol.112 , pp. 1974
    • Glass, B.1    Hasenkamp, J.2    Gorlitz, A.3
  • 87
    • 84855744204 scopus 로고    scopus 로고
    • Invivo B-cell depletion with rituximab for alternative donor hemopoietic SCT
    • Dominietto A., Tedone E., Soracco M., et al. Invivo B-cell depletion with rituximab for alternative donor hemopoietic SCT. Bone Marrow Transplant 2012, 47:101-106.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 101-106
    • Dominietto, A.1    Tedone, E.2    Soracco, M.3


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