A novel framework for interpretation of data from the fish short-term reproduction assay (FSTRA) for the detection of endocrine-disrupting chemicals

Environmental Toxicology and Chemistry

Volumn 33, Issue 11, 2014, Pages 2529-2540

  Ankley, Gerald T ^a   Jensen, Kathleen M ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Endocrine disrupting chemicals; Fish; Regulation; Reproduction; Screening

Indexed keywords

ASSAYS; CHEMICAL DETECTION; ENDOCRINE DISRUPTERS; ENVIRONMENTAL PROTECTION AGENCY; FISH; PHYSIOLOGICAL MODELS; POINT CONTACTS; SCREENING; WAVE PLASMA INTERACTIONS;

ENDOCRINE DISRUPTING CHEMICALS; ENDOCRINE DISRUPTOR; INTERPRETATION OF DATA; PATHWAY IDENTIFICATION; REGULATION; REPRODUCTION; US ENVIRONMENTAL PROTECTION AGENCY; WEIGHT OF EVIDENCES;

CHEMICALS;

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 17ALPHA ESTRADIOL; 17ALPHA TRENBOLONE; ANDROGEN RECEPTOR; ANDROSTENEDIONE; AROMATASE; BICALUTAMIDE; DUTASTERIDE; ENDOCRINE DISRUPTOR; ESTRADIOL; ESTROGEN RECEPTOR; ETHINYLESTRADIOL; FADROZOLE; FENARIMOL; FLUTAMIDE; HALOPERIDOL; KETOCONAZOLE; LEVONORGESTREL; MESSENGER RNA; METHOXYCHLOR; METHYLTESTOSTERONE; PROCHLORAZ; PROGESTERONE; PROPICONAZOLE; SPIRONOLACTONE; TESTOSTERONE; TRENBOLONE; TRILOSTANE; VINCLOZOLIN; VITELLOGENIN; ANDROGEN; ANDROGEN RECEPTOR ANTAGONIST; ESTROGEN;

ANDROGEN; BIOASSAY; CONCENTRATION (COMPOSITION); CYPRINID; DATA INTERPRETATION; DETECTION METHOD; ENDOCRINE DISRUPTOR; ENVIRONMENTAL PROTECTION; ENZYME ACTIVITY; ESTROGENIC COMPOUND; HISTOPATHOLOGY; INHIBITION; PHYSIOLOGICAL RESPONSE; POLLUTION EXPOSURE; PROTEIN; REPRODUCTION; SECONDARY SEXUAL CHARACTERISTICS; STEROID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EGG PRODUCTION; ENVIRONMENTAL MONITORING; ENVIRONMENTAL PROTECTION; FEMALE; FISH; FISH SHORT TERM REPRODUCTION ASSAY; GONAD; HISTOPATHOLOGY; MALE; NONHUMAN; PIMEPHALES PROMELAS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REPRODUCTIVE TOXICITY; SEXUAL DEVELOPMENT; STEROID BLOOD LEVEL; STEROIDOGENESIS; VITELLOGENESIS; ANIMAL; BIOASSAY; CHEMISTRY; CYPRINIFORMES; DRUG EFFECTS; ENDOCRINE SYSTEM; GOVERNMENT; METABOLISM; PHYSIOLOGY; REPRODUCTION; UNITED STATES;

UNITED STATES;

PIMEPHALES PROMELAS;

ANDROGEN RECEPTOR ANTAGONISTS; ANDROGENS; ANIMALS; BIOLOGICAL ASSAY; CYPRINIDAE; ENDOCRINE DISRUPTORS; ENDOCRINE SYSTEM; ESTROGENS; FEMALE; GONADS; MALE; RECEPTORS, ANDROGEN; REPRODUCTION; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY; VITELLOGENINS;

EID: 84926492328     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.2708     Document Type: Article

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