Ketoconazole in the fathead minnow (Pimephales promelas): Reproductive toxicity and biological compensation

Environmental Toxicology and Chemistry

Volumn 26, Issue 6, 2007, Pages 1214-1223

  Ankley, Gerald T ^a   Jensen, Kathleen M ^a   Kahl, Michael D ^a   Makynen, Elizabeth A ^a   Blake, Lindsey S ^a   Greene, Katie J ^a   Johnson, Rodney D ^a   Villeneuve, Daniel L ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Compensation; Endocrine function; Fish; Ketoconazole; Reproductive effects

Indexed keywords

BIOACTIVITY; BIOSYNTHESIS; CHOLESTEROL; CONCENTRATION (PROCESS); FUNGI; FUNGICIDES; GROWTH KINETICS; WATER;

BIOLOGICAL COMPENSATION; ENDOCRINE FUNCTIONS; KETOCONAZOLE (KTC); REPRODUCTIVE EFFECTS;

TOXICITY;

CYTOCHROME P450; CYTOCHROME P450 17; ESTRADIOL; KETOCONAZOLE; OXYGENASE; TESTOSTERONE; WATER;

ASSESSMENT METHOD; CONCENTRATION (COMPOSITION); CYPRINID; EGG PRODUCTION; FUNGICIDE; PHYSIOLOGICAL RESPONSE; REPRODUCTION; SPAWNING POPULATION; TESTOSTERONE; TOXICITY TEST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; COMPENSATION; CONTROLLED STUDY; EGG PRODUCTION; EX VIVO STUDY; FEMALE; FISH; GONAD; LEYDIG CELL; MALE; NONHUMAN; PRIORITY JOURNAL; REPRODUCTION; REPRODUCTIVE TOXICITY; STEROIDOGENESIS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTIFUNGAL AGENTS; CYPRINIDAE; CYTOCHROME P-450 ENZYME SYSTEM; KETOCONAZOLE; REPRODUCTION; RNA, MESSENGER;

MAMMALIA; PIMEPHALES PROMELAS; VERTEBRATA;

EID: 34250622120     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/06-428R.1     Document Type: Article

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