Ubiquitinated Sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival

Journal of Biological Chemistry

Volumn 290, Issue 14, 2015, Pages 8904-8912

  Peng, Lirong ^a   Yuan, Zhigang ^a   Li, Yixuan ^a   Ling, Hongbo ^a   Izumi, Victoria ^a   Fang, Bin ^a   Fukasawa, Kenji ^a   Koomen, John ^a   Chen, Jiandong ^a   Seto, Edward ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; DNA; PHYSIOLOGICAL MODELS; PHYSIOLOGY;

DNA DAMAGE RESPONSE; ENZYMATIC ACTIVITIES; HISTONE DEACETYLASES; NORMAL CONDITION; NUCLEAR LOCALIZATION; PATHOLOGICAL CELLS; PATHOLOGICAL PROCESS; POST-TRANSLATIONAL MODIFICATIONS;

CELL SIGNALING;

HISTONE DEACETYLASE; PROTEIN MDM2; SIRTUIN 1; MDM2 PROTEIN, HUMAN; PRIMER DNA; SIRT1 PROTEIN, HUMAN;

ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME DEGRADATION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; UBIQUITINATION; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; WESTERN BLOTTING;

BASE SEQUENCE; BLOTTING, WESTERN; CELL DEATH; CELL LINE; CELL SURVIVAL; DNA DAMAGE; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; PROTO-ONCOGENE PROTEINS C-MDM2; SIRTUIN 1; UBIQUITINATION;

EID: 84926429973     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.612796     Document Type: Article

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