HECT domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting dishevelled for proteasomal degradation

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8289-8298

  Ding, Yi ^a   Zhang, Yan ^a   Xu, Chao ^a   Tao, Qing Hua ^a   Chen, Ye Guang ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL POLARITY; NEGATIVE FEEDBACK REGULATORS; POLYUBIQUITINATION; PROTEASOMAL DEGRADATION; UBIQUITIN LIGASES; UBIQUITINATION; WNT SIGNALING; XENOPUS EMBRYO;

SIGNALING;

CELL SIGNALING;

BETA CATENIN; DISHEVELLED 2; PROTEASOME; STRESS ACTIVATED PROTEIN KINASE; UBIQUITIN PROTEIN LIGASE NEDD4; WNT5A PROTEIN;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; UBIQUITINATION; WNT SIGNALING PATHWAY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; ANIMALS; CONSERVED SEQUENCE; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; FEEDBACK, PHYSIOLOGICAL; HEK293 CELLS; HELA CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; WNT SIGNALING PATHWAY; XENOPUS LAEVIS;

EID: 84875416382     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.433185     Document Type: Article

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