Nutraceutical oleuropein supplementation prevents high fat diet-induced adiposity in mice

Journal of Functional Foods

Volumn 14, Issue , 2015, Pages 702-715

  van der Stelt, Inge ^a   Hoek van den Hil, Elise F ^a   Swarts, Hans J M ^a   Vervoort, Jacques J M ^a   Hoving, Lisa ^a   Skaltsounis, Leandros ^b   Lemonakis, Nikolaos ^b   Andreadou, Ioanna ^b   van Schothorst, Evert M ^a   Keijer, Jaap ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

Adiposity; Energy balance; Functional food ingredient; Lipid metabolism; Obesity; Polyphenol

Indexed keywords

MUS; OLEACEAE;

EID: 84926379773     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2015.02.040     Document Type: Article

References (50)

1. Abbott C.R., Monteiro M., Small C.J., Sajedi A., Smith K.L., Parkinson J.R., Ghatei M.A., Bloom S.R. The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Research 2005, 1044:127-131.
2. Amiot M.J., Fleuriet A., Macheix J.J. Importance and evolution of phenolic-compounds in olive during growth and maturation. Journal of Agricultural and Food Chemistry 1986, 34:823-826.
3. Andreadou I., Iliodromitis E.K., Mikros E., Constantinou M., Agalias A., Magiatis P., Skaltsounis A.L., Kamber E., Tsantili-Kakoulidou A., Kremastinos D.T. The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits. The Journal of Nutrition 2006, 136:2213-2219.
4. Andreadou I., Mikros E., Ioannidis K., Sigala F., Naka K., Kostidis S., Farmakis D., Tenta R., Kavantzas N., Bibli S.I., Gikas E., Skaltsounis L., Kremastinos D.T., Iliodromitis E.K. Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism. Journal of Molecular and Cellular Cardiology 2014, 69:4-16.
5. Bonoli M., Bendini A., Cerretani L., Lercker G., Toschi T.G. Qualitative and semiquantitative analysis of phenolic compounds in extra virgin olive oils as a function of the ripening degree of olive fruits by different analytical techniques. Journal of Agricultural and Food Chemistry 2004, 52:7026-7032.
6. Bustin S.A., Benes V., Garson J.A., Hellemans J., Huggett J., Kubista M., Mueller R., Nolan T., Pfaffl M.W., Shipley G.L., Vandesompele J., Wittwer C.T. The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments. Clinical Chemistry 2009, 55:611-622.
7. Cabou C., Burcelin R. GLP-1, the gut-brain, and brain-periphery axes. The Review of Diabetic Studies 2011, 8:418-431.
8. Cummings D.E., Overduin J. Gastrointestinal regulation of food intake. The Journal of Clinical Investigation 2007, 117:13-23.
9. de Bock M., Derraik J.G., Brennan C.M., Biggs J.B., Morgan P.E., Hodgkinson S.C., Hofman P.L., Cutfield W.S. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: A randomized, placebo-controlled, crossover trial. PLoS ONE 2013, 8:e57622.
10. de Bock M., Thorstensen E.B., Derraik J.G., Henderson H.V., Hofman P.L., Cutfield W.S. Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract. Molecular Nutrition & Food Research 2013, 57:2079-2085.
11. de Boer V.C., Dihal A.A., van der Woude H., Arts I.C., Wolffram S., Alink G.M., Rietjens I.M., Keijer J., Hollman P.C. Tissue distribution of quercetin in rats and pigs. The Journal of Nutrition 2005, 135:1718-1725.
12. Dao T.M., Waget A., Klopp P., Serino M., Vachoux C., Pechere L., Drucker D.J., Champion S., Barthelemy S., Barra Y., Burcelin R., Seree E. Resveratrol increases glucose induced GLP-1 secretion in mice: A mechanism which contributes to the glycemic control. PLoS ONE 2011, 6:e20700.
13. Duivenvoorde L.P., van Schothorst E.M., Swarts H.J., Keijer J. Assessment of metabolic flexibility of old and adult mice using three noninvasive, indirect calorimetry-based treatments. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2015, 70:282-293.
14. Ebaid G.M., Seiva F.R., Rocha K.K., Souza G.A., Novelli E.L. Effects of olive oil and its minor phenolic constituents on obesity-induced cardiac metabolic changes. Nutrition Journal 2010, 9:46.
15. Eguchi J., Wada J., Hida K., Zhang H., Matsuoka T., Baba M., Hashimoto I., Shikata K., Ogawa N., Makino H. Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity. The Biochemical Journal 2005, 387:343-353.
16. Hamdi H.K., Castellon R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochemical and Biophysical Research Communications 2005, 334:769-778.
17. Hamers F.P., Lankhorst A.J., van Laar T.J., Veldhuis W.B., Gispen W.H. Automated quantitative gait analysis during overground locomotion in the rat: Its application to spinal cord contusion and transection injuries. Journal of Neurotrauma 2001, 18:187-201.
18. Han J., Talorete T.P., Yamada P., Isoda H. Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology 2009, 59:45-53.
19. Hassen I., Casabianca H., Hosni K. Biological activities of the natural antioxidant oleuropein: Exceeding the expectation - A mini review. Journal of Functional Foods 2014, 10.1016/j.jff.2014.1009.1001.
20. Hoek-van den Hil E.F., Keijer J., Bunschoten A., Vervoort J.J., Stankova B., Bekkenkamp M., Herreman L., Venema D., Hollman P.C., Tvrzicka E., Rietjens I.M., van Schothorst E.M. Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice. PLoS ONE 2013, 8:e51588.
21. Hoek-van den Hil E.F., van Schothorst E.M., van der Stelt I., Swarts H.J.M., Venema D., Sailer M., Vervoort J.J.M., Hollman P.C.H., Rietjens I.M.C.M., Keijer J. Quercetin decreases high-fat diet induced body weight gain and accumulation of hepatic and circulating lipids in mice. Genes and Nutrition 2014, 9:1-8.
22. Hoevenaars F.P.M., Bekkenkamp-Grovenstein M., Janssen R.J.R.J., Heil S.G., Bunschoten A., Hoek-van den Hil E.F., Snaas-Alders S., Teerds K., van Schothorst E.M., Keijer J. Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences. Molecular Nutrition & Food Research 2014, 58:799-807.
23. Hoevenaars F.P.M., Keijer J., Herreman L., Palm I., Hegeman M.A., Swarts H.J.M., van Schothorst E.M. Adipose tissue metabolism and inflammation are differently affected by weight loss in obese mice due to either a high-fat diet restriction or change to a low-fat diet. Genes and Nutrition 2014, 9:391.
24. Hoevenaars F.P., van Schothorst E.M., Horakova O., Voigt A., Rossmeisl M., Pico C., Caimari A., Kopecky J., Klaus S., Keijer J. BIOCLAIMS standard diet (BIOsd): A reference diet for nutritional physiology. Genes and Nutrition 2012, 7:399-404.
25. Impellizzeri D., Esposito E., Mazzon E., Paterniti I., Di Paola R., Morittu V.M., Procopio A., Britti D., Cuzzocrea S. Oleuropein aglycone, an olive oil compound, ameliorates development of arthritis caused by injection of collagen type II in mice. The Journal of Pharmacology and Experimental Therapeutics 2011, 339:859-869.
26. Keys A., Menotti A., Aravanis C., Blackburn H., Djordevic B.S., Buzina R., Dontas A.S., Fidanza F., Karvonen M.J., Kimura N., Mohacek I., Nedeljkovic S., Puddu V., Punsar S., Taylor H.L., Conti S., Kromhout D., Toshima H. The seven countries study: 2,289 deaths in 15 years. Preventive Medicine 1984, 13:141-154.
27. Kim S., Jin Y., Choi Y., Park T. Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice. Biochemical Pharmacology 2011, 81:1343-1351.
28. Kim Y., Choi Y., Park T. Hepatoprotective effect of oleuropein in mice: Mechanisms uncovered by gene expression profiling. Biotechnology Journal 2010, 5:950-960.
29. Klaus S., Pultz S., Thone-Reineke C., Wolfram S. Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation. International Journal of Obesity 2005, 29:615-623.
30. Le Tutour B., Guedon D. Antioxidative activities of Olea europaea leaves and related phenolic compounds. Phytochemistry 1992, 31:1173-1178.
31. Lin P., Qian W., Wang X., Cao L., Li S., Qian T. The biotransformation of oleuropein in rats. Biomedical Chromatography 2013, 27:1162-1167.
32. Meeran K., O'Shea D., Edwards C.M., Turton M.D., Heath M.M., Gunn I., Abusnana S., Rossi M., Small C.J., Goldstone A.P., Taylor G.M., Sunter D., Steere J., Choi S.J., Ghatei M.A., Bloom S.R. Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat. Endocrinology 1999, 140:244-250.
33. Nogueiras R., Perez-Tilve D., Veyrat-Durebex C., Morgan D.A., Varela L., Haynes W.G., Patterson J.T., Disse E., Pfluger P.T., Lopez M., Woods S.C., DiMarchi R., Dieguez C., Rahmouni K., Rohner-Jeanrenaud F., Tschop M.H. Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity. The Journal of neuroscience 2009, 29:5916-5925.
34. Oi-Kano Y., Kawada T., Watanabe T., Koyama F., Watanabe K., Senbongi R., Iwai K. Oleuropein, a phenolic compound in extra virgin olive oil, increases uncoupling protein 1 content in brown adipose tissue and enhances noradrenaline and adrenaline secretions in rats. Journal of Nutritional Science and Vitaminology 2008, 54:363-370.
35. Oliveras-Lopez M.J., Berna G., Jurado-Ruiz E., de la Serrana H.L.G., Martin F. Consumption of extra-virgin olive oil rich in phenolic compounds has beneficial antioxidant effects in healthy human adults. Journal of Functional Foods 2014, 10:475-484.
36. Park S., Choi Y., Um S.J., Yoon S.K., Park T. Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice. Journal of Hepatology 2011, 54:984-993.
37. Polzonetti V., Egidi D., Vita A., Vincenzetti S., Natalini P. Involvement of oleuropein in (some) digestive metabolic pathways. Food Chemistry 2004, 88:11-15.
38. Reagan-Shaw S., Nihal M., Ahmad N. Dose translation from animal to human studies revisited. FASEB Journal 2008, 22:659-661.
39. Sackmann-Sala L., Berryman D.E., Munn R.D., Lubbers E.R., Kopchick J.J. Heterogeneity among white adipose tissue depots in male C57BL/6J mice. Obesity 2012, 20:101-111.
40. Sepporta M.V., Fuccelli R., Rosignoli P., Ricci G., Servili M., Morozzi G., Fabiani R. Oleuropein inhibits tumour growth and metastases dissemination in ovariectomised nude mice with MCF-7 human breast tumour xenografts. Journal of Functional Foods 2014, 8:269-273.
41. Tschop M.H., Speakman J.R., Arch J.R., Auwerx J., Bruning J.C., Chan L., Eckel R.H., Farese R.V., Galgani J.E., Hambly C., Herman M.A., Horvath T.L., Kahn B.B., Kozma S.C., Maratos-Flier E., Muller T.D., Munzberg H., Pfluger P.T., Plum L., Reitman M.L., Rahmouni K., Shulman G.I., Thomas G., Kahn C.R., Ravussin E. A guide to analysis of mouse energy metabolism. Nature Methods 2012, 9:57-63.
42. Van Schothorst E.M., Bunschoten A., Hoevenaars F.P., van der Stelt I., Janovska P., Venema D., Kopecky J., Hollman P.C., Keijer J. Direct comparison of health effects by dietary polyphenols at equimolar doses in wildtype moderate high-fat fed C57BL/6JolaHsd mice. Food Research International 2014, 65:95-102.
43. Van Schothorst E.M., Franssen-van Hal N., Schaap M.M., Pennings J., Hoebee B., Keijer J. Adipose gene expression patterns of weight gain suggest counteracting steroid hormone synthesis. Obesity Research 2005, 13:1031-1041.
44. Verdich C., Flint A., Gutzwiller J.P., Naslund E., Beglinger C., Hellstrom P.M., Long S.J., Morgan L.M., Holst J.J., Astrup A. A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans. The Journal of Clinical Endocrinology and Metabolism 2001, 86:4382-4389.
45. Visioli F., Bellomo G., Galli C. Free radical-scavenging properties of olive oil polyphenols. Biochemical and Biophysical Research Communications 1998, 247:60-64.
46. Visioli F., Bellosta S., Galli C. Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages. Life Sciences 1998, 62:541-546.
47. Visioli F., Galli C. Biological properties of olive oil phytochemicals. Critical Reviews in Food Science and Nutrition 2002, 42:209-221.
48. Vissers M.N., Zock P.L., Roodenburg A.J., Leenen R., Katan M.B. Olive oil phenols are absorbed in humans. The Journal of Nutrition 2002, 132:409-417.
49. Zbakh H., El Abbassi A. Potential use of olive mill wastewater in the preparation of functional beverages: A review. Journal of Functional Foods 2012, 4:53-65.
50. Zoidou E., Melliou E., Gikas E., Tsarbopoulos A., Magiatis P., Skaltsounis A.L. Identification of Throuba Thassos, a traditional Greek table olive variety, as a nutritional rich source of oleuropein. Journal of Agricultural and Food Chemistry 2010, 58:46-50.