Mitochondrial Dysfunction Reveals the Role of mRNA Poly(A) Tail Regulation in Oculopharyngeal Muscular Dystrophy Pathogenesis

PLoS Genetics

Volumn 11, Issue 3, 2015, Pages

  Chartier, Aymeric ^a   Klein, Pierre ^b   Pierson, Stéphanie ^a   Barbezier, Nicolas ^a   Gidaro, Teresa ^b   Casas, François ^c   Carberry, Steven ^d   Dowling, Paul ^d   Maynadier, Laurie ^a   Bellec, Maëlle ^a   Oloko, Martine ^b   Jardel, Claude ^e   Moritz, Bodo ^f   Dickson, George ^g   Mouly, Vincent ^b   Ohlendieck, Kay ^d   Butler Browne, Gillian ^b   Trollet, Capucine ^b   Simonelig, Martine ^a  

^a INSTITUTE OF HUMAN GENETICS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c University of Montpellier   (France)

^d NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^e ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^f MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^g UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SYNTHASE; CYTOCHROME C; MITOCHONDRIAL PROTEIN; POLYADENYLATED RNA; POLYADENYLIC ACID BINDING PROTEIN; POLYADENYLIC ACID BINDING PROTEIN NUCLEAR 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; RNA BINDING PROTEIN; SMAUG PROTEIN; SUCCINATE DEHYDROGENASE; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; MESSENGER RNA; PABPN1 PROTEIN, HUMAN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CCR4 GENE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DROSOPHILA; ENZYME ACTIVITY; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; MUSCLE BIOPSY; NONHUMAN; OCULOPHARYNGEAL MUSCULAR DYSTROPHY; PABP2 GENE; PABPN1 17ALA GENE; PHENOTYPE; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEIN MODIFICATION; RNA ANALYSIS; RNA CLEAVAGE; RNA STABILITY; RNA STRUCTURE; SMG GENE; TRANSCRIPTOMICS; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENETICS; PATHOLOGY; POLYADENYLATION; SKELETAL MUSCLE;

ANIMALS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HUMANS; MICE; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, OCULOPHARYNGEAL; POLY(A)-BINDING PROTEIN I; POLYADENYLATION; RNA, MESSENGER;

EID: 84926362619     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005092     Document Type: Article

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