Mechanisms that lead to the regulation of NLRP3 inflammasome expression and activation in human dental pulp fibroblasts

Molecular Immunology

Volumn 66, Issue 2, 2015, Pages 253-262

  Zhang, Ansheng ^a   Wang, Peina ^a   Ma, Xiaoying ^b   Yin, Xiao ^a   Li, Jiguo ^a   Wang, Haijing ^a   Jiang, Wenkai ^a   Jia, Qian ^a   Ni, Longxing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b The 323 Hospital of PLA   (China)

Author keywords

Human dental pulp fibroblasts; Innate immunity; NLRP3 inflammasome; Reactive oxygen species; TLR

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; CRYOPYRIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LENTIVIRUS VECTOR; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; SUPEROXIDE; TOLL LIKE RECEPTOR 4; CARRIER PROTEIN; I KAPPA B; MYD88 PROTEIN, HUMAN; NF-KAPPAB INHIBITOR ALPHA; NLRP3 PROTEIN, HUMAN; PEPTIDE; SMALL INTERFERING RNA; TLR4 PROTEIN, HUMAN;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SIMULATION; TOOTH PULP; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; PREMOLAR TOOTH; PRIMARY CELL CULTURE; TOOTH EXTRACTION;

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; BICUSPID; CARRIER PROTEINS; CASPASE 1; DENTAL PULP; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MYELOID DIFFERENTIATION FACTOR 88; PEPTIDES; PHOSPHORYLATION; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TOOTH EXTRACTION;

EID: 84926290803     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.03.009     Document Type: Article

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