메뉴 건너뛰기




Volumn 11, Issue 3, 2015, Pages

HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; HISTONE DEACETYLASE 4; MYOGENIN; HDAC5 PROTEIN, MOUSE; HISTONE DEACETYLASE; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, MOUSE;

EID: 84926191823     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005021     Document Type: Article
Times cited : (54)

References (69)
  • 2
    • 0027432418 scopus 로고
    • Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues
    • Strong TV, Tagle DA, Valdes JM, Elmer LW, Boehm K, et al. (1993) Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues. Nat Genet 5: 259–265. 8275091
    • (1993) Nat Genet , vol.5 , pp. 259-265
    • Strong, T.V.1    Tagle, D.A.2    Valdes, J.M.3    Elmer, L.W.4    Boehm, K.5
  • 3
    • 0027484673 scopus 로고
    • Huntington's disease gene (IT15) is widely expressed in human and rat tissues
    • Li SH, Schilling G, Young WS, 3rdLi XJ, Margolis RL, et al. (1993) Huntington's disease gene (IT15) is widely expressed in human and rat tissues. Neuron 11: 985–993. 8240819
    • (1993) Neuron , vol.11 , pp. 985-993
    • Li, S.H.1    Schilling, G.2    Young, W.S.3    Li, X.J.4    Margolis, R.L.5
  • 4
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • Li SH, Li XJ, (2004) Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet 20: 146–154. 15036808
    • (2004) Trends Genet , vol.20 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 5
    • 33744921670 scopus 로고    scopus 로고
    • Expression and characterization of full-length human huntingtin, an elongated HEAT repeat protein
    • Li W, Serpell LC, Carter WJ, Rubinsztein DC, Huntington JA, (2006) Expression and characterization of full-length human huntingtin, an elongated HEAT repeat protein. J Biol Chem 281: 15916–15922. 16595690
    • (2006) J Biol Chem , vol.281 , pp. 15916-15922
    • Li, W.1    Serpell, L.C.2    Carter, W.J.3    Rubinsztein, D.C.4    Huntington, J.A.5
  • 6
    • 0041656292 scopus 로고    scopus 로고
    • The hunt for huntingtin function: interaction partners tell many different stories
    • Harjes P, Wanker EE, (2003) The hunt for huntingtin function: interaction partners tell many different stories. Trends Biochem Sci 28: 425–433. 12932731
    • (2003) Trends Biochem Sci , vol.28 , pp. 425-433
    • Harjes, P.1    Wanker, E.E.2
  • 7
    • 84993912315 scopus 로고
    • Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
    • Zeitlin S, Liu JP, Chapman DL, Papaioannou VE, Efstratiadis A, (1995) Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nat Genet 11: 155–163. 7550343
    • (1995) Nat Genet , vol.11 , pp. 155-163
    • Zeitlin, S.1    Liu, J.P.2    Chapman, D.L.3    Papaioannou, V.E.4    Efstratiadis, A.5
  • 8
    • 0033119123 scopus 로고    scopus 로고
    • Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology
    • Gutekunst CA, Li SH, Yi H, Mulroy JS, Kuemmerle S, et al. (1999) Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. J Neurosci 19: 2522–2534. 10087066
    • (1999) J Neurosci , vol.19 , pp. 2522-2534
    • Gutekunst, C.A.1    Li, S.H.2    Yi, H.3    Mulroy, J.S.4    Kuemmerle, S.5
  • 9
    • 77649297870 scopus 로고    scopus 로고
    • Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease
    • Sathasivam K, Lane A, Legleiter J, Warley A, Woodman B, et al. (2010) Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease. Hum Mol Genet 19: 65–78. doi: 10.1093/hmg/ddp467 19825844
    • (2010) Hum Mol Genet , vol.19 , pp. 65-78
    • Sathasivam, K.1    Lane, A.2    Legleiter, J.3    Warley, A.4    Woodman, B.5
  • 10
    • 77950547661 scopus 로고    scopus 로고
    • Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease
    • Moffitt H, McPhail GD, Woodman B, Hobbs C, Bates GP, (2009) Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease. PLoS One 4: e8025. doi: 10.1371/journal.pone.0008025 19956633
    • (2009) PLoS One , vol.4 , pp. 8025
    • Moffitt, H.1    McPhail, G.D.2    Woodman, B.3    Hobbs, C.4    Bates, G.P.5
  • 12
    • 44449104300 scopus 로고    scopus 로고
    • Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure
    • Pattison JS, Sanbe A, Maloyan A, Osinska H, Klevitsky R, et al. (2008) Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure. Circulation 117: 2743–2751. doi: 10.1161/CIRCULATIONAHA.107.750232 18490523
    • (2008) Circulation , vol.117 , pp. 2743-2751
    • Pattison, J.S.1    Sanbe, A.2    Maloyan, A.3    Osinska, H.4    Klevitsky, R.5
  • 13
    • 84944718721 scopus 로고    scopus 로고
    • Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease
    • Mielcarek M, Inuabasi L, Bondulich MK, Muller T, Osborne GF, et al. (2014) Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease. PLoS Genet 10: e1004550. doi: 10.1371/journal.pgen.1004550 25101683
    • (2014) PLoS Genet , vol.10 , pp. 1004550
    • Mielcarek, M.1    Inuabasi, L.2    Bondulich, M.K.3    Muller, T.4    Osborne, G.F.5
  • 14
    • 84907484531 scopus 로고    scopus 로고
    • The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model
    • Mielcarek M, Bondulich MK, Inuabasi L, Franklin SA, Muller T, et al. (2014) The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model. PLoS One 9: e108961. doi: 10.1371/journal.pone.0108961 25268775
    • (2014) PLoS One , vol.9 , pp. 108961
    • Mielcarek, M.1    Bondulich, M.K.2    Inuabasi, L.3    Franklin, S.A.4    Muller, T.5
  • 15
    • 67650095269 scopus 로고    scopus 로고
    • Beyond the brain: widespread pathology in Huntington's disease
    • van der Burg JM, Bjorkqvist M, Brundin P, (2009) Beyond the brain: widespread pathology in Huntington's disease. Lancet Neurol 8: 765–774. doi: 10.1016/S1474-4422(09)70178-4 19608102
    • (2009) Lancet Neurol , vol.8 , pp. 765-774
    • van der Burg, J.M.1    Bjorkqvist, M.2    Brundin, P.3
  • 18
    • 0037101835 scopus 로고    scopus 로고
    • Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
    • Luthi-Carter R, Hanson SA, Strand AD, Bergstrom DA, Chun W, et al. (2002) Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum Mol Genet 11: 1911–1926. 12165554
    • (2002) Hum Mol Genet , vol.11 , pp. 1911-1926
    • Luthi-Carter, R.1    Hanson, S.A.2    Strand, A.D.3    Bergstrom, D.A.4    Chun, W.5
  • 19
    • 25844526181 scopus 로고    scopus 로고
    • Gene expression in Huntington's disease skeletal muscle: a potential biomarker
    • Strand AD, Aragaki AK, Shaw D, Bird T, Holton J, et al. (2005) Gene expression in Huntington's disease skeletal muscle: a potential biomarker. Hum Mol Genet 14: 1863–1876. 15888475
    • (2005) Hum Mol Genet , vol.14 , pp. 1863-1876
    • Strand, A.D.1    Aragaki, A.K.2    Shaw, D.3    Bird, T.4    Holton, J.5
  • 20
    • 0033914747 scopus 로고    scopus 로고
    • Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy
    • Lodi R, Schapira AH, Manners D, Styles P, Wood NW, et al. (2000) Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy. Ann Neurol 48: 72–76. 10894218
    • (2000) Ann Neurol , vol.48 , pp. 72-76
    • Lodi, R.1    Schapira, A.H.2    Manners, D.3    Styles, P.4    Wood, N.W.5
  • 21
    • 22844440902 scopus 로고    scopus 로고
    • Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease
    • Saft C, Zange J, Andrich J, Muller K, Lindenberg K, et al. (2005) Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease. Mov Disord 20: 674–679. 15704211
    • (2005) Mov Disord , vol.20 , pp. 674-679
    • Saft, C.1    Zange, J.2    Andrich, J.3    Muller, K.4    Lindenberg, K.5
  • 22
    • 79951492653 scopus 로고    scopus 로고
    • Low anaerobic threshold and increased skeletal muscle lactate production in subjects with Huntington's disease
    • Ciammola A, Sassone J, Sciacco M, Mencacci NE, Ripolone M, et al. (2011) Low anaerobic threshold and increased skeletal muscle lactate production in subjects with Huntington's disease. Mov Disord 26: 130–137. doi: 10.1002/mds.23258 20931633
    • (2011) Mov Disord , vol.26 , pp. 130-137
    • Ciammola, A.1    Sassone, J.2    Sciacco, M.3    Mencacci, N.E.4    Ripolone, M.5
  • 23
    • 70349422148 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease
    • Quintanilla RA, Johnson GV, (2009) Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease. Brain Res Bull 80: 242–247. doi: 10.1016/j.brainresbull.2009.07.010 19622387
    • (2009) Brain Res Bull , vol.80 , pp. 242-247
    • Quintanilla, R.A.1    Johnson, G.V.2
  • 24
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin J, Handschin C, Spiegelman BM, (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 1: 361–370. 16054085
    • (2005) Cell Metab , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 25
    • 84863011541 scopus 로고    scopus 로고
    • Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
    • Johri A, Calingasan NY, Hennessey TM, Sharma A, Yang L, et al. (2012) Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease. Hum Mol Genet 21: 1124–1137. doi: 10.1093/hmg/ddr541 22095692
    • (2012) Hum Mol Genet , vol.21 , pp. 1124-1137
    • Johri, A.1    Calingasan, N.Y.2    Hennessey, T.M.3    Sharma, A.4    Yang, L.5
  • 26
    • 27144524290 scopus 로고    scopus 로고
    • Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models
    • Fujimoto M, Takaki E, Hayashi T, Kitaura Y, Tanaka Y, et al. (2005) Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models. J Biol Chem 280: 34908–34916. 16051598
    • (2005) J Biol Chem , vol.280 , pp. 34908-34916
    • Fujimoto, M.1    Takaki, E.2    Hayashi, T.3    Kitaura, Y.4    Tanaka, Y.5
  • 27
    • 16044373842 scopus 로고    scopus 로고
    • Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
    • Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, et al. (1996) Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87: 493–506. 8898202
    • (1996) Cell , vol.87 , pp. 493-506
    • Mangiarini, L.1    Sathasivam, K.2    Seller, M.3    Cozens, B.4    Harper, A.5
  • 28
  • 29
    • 33847684865 scopus 로고    scopus 로고
    • The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes
    • Woodman B, Butler R, Landles C, Lupton MK, Tse J, et al. (2007) The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes. Brain Res Bull 72: 83–97. 17352931
    • (2007) Brain Res Bull , vol.72 , pp. 83-97
    • Woodman, B.1    Butler, R.2    Landles, C.3    Lupton, M.K.4    Tse, J.5
  • 30
    • 84873463075 scopus 로고    scopus 로고
    • Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
    • Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, et al. (2013) Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Proc Natl Acad Sci U S A 110: 2366–2370. doi: 10.1073/pnas.1221891110 23341618
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 2366-2370
    • Sathasivam, K.1    Neueder, A.2    Gipson, T.A.3    Landles, C.4    Benjamin, A.C.5
  • 32
    • 84875427900 scopus 로고    scopus 로고
    • Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
    • Mitchell JC, McGoldrick P, Vance C, Hortobagyi T, Sreedharan J, et al. (2013) Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion. Acta Neuropathol 125: 273–288. doi: 10.1007/s00401-012-1043-z 22961620
    • (2013) Acta Neuropathol , vol.125 , pp. 273-288
    • Mitchell, J.C.1    McGoldrick, P.2    Vance, C.3    Hortobagyi, T.4    Sreedharan, J.5
  • 33
    • 61349179577 scopus 로고    scopus 로고
    • Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype
    • Tsika RW, Schramm C, Simmer G, Fitzsimons DP, Moss RL, et al. (2008) Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype. J Biol Chem 283: 36154–36167. doi: 10.1074/jbc.M807461200 18978355
    • (2008) J Biol Chem , vol.283 , pp. 36154-36167
    • Tsika, R.W.1    Schramm, C.2    Simmer, G.3    Fitzsimons, D.P.4    Moss, R.L.5
  • 34
    • 37549049708 scopus 로고    scopus 로고
    • MCAT elements and the TEF-1 family of transcription factors in muscle development and disease
    • Yoshida T, (2008) MCAT elements and the TEF-1 family of transcription factors in muscle development and disease. Arterioscler Thromb Vasc Biol 28: 8–17. 17962623
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 8-17
    • Yoshida, T.1
  • 35
    • 0042092011 scopus 로고    scopus 로고
    • Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions
    • Karasseva N, Tsika G, Ji J, Zhang A, Mao X, et al. (2003) Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions. Mol Cell Biol 23: 5143–5164. 12861002
    • (2003) Mol Cell Biol , vol.23 , pp. 5143-5164
    • Karasseva, N.1    Tsika, G.2    Ji, J.3    Zhang, A.4    Mao, X.5
  • 36
    • 33644632444 scopus 로고    scopus 로고
    • Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway
    • Zhao P, Caretti G, Mitchell S, McKeehan WL, Boskey AL, et al. (2006) Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway. J Biol Chem 281: 429–438. 16267055
    • (2006) J Biol Chem , vol.281 , pp. 429-438
    • Zhao, P.1    Caretti, G.2    Mitchell, S.3    McKeehan, W.L.4    Boskey, A.L.5
  • 37
    • 1342342827 scopus 로고    scopus 로고
    • VITO-1, a novel vestigial related protein is predominantly expressed in the skeletal muscle lineage
    • Mielcarek M, Gunther S, Kruger M, Braun T, (2002) VITO-1, a novel vestigial related protein is predominantly expressed in the skeletal muscle lineage. Mech Dev 119 Suppl 1: S269–274. 14516696
    • (2002) Mech Dev , vol.119 , pp. 269-274
    • Mielcarek, M.1    Gunther, S.2    Kruger, M.3    Braun, T.4
  • 38
    • 58749098559 scopus 로고    scopus 로고
    • VITO-2, a new SID domain protein, is expressed in the myogenic lineage during early mouse embryonic development
    • Mielcarek M, Piotrowska I, Schneider A, Gunther S, Braun T, (2009) VITO-2, a new SID domain protein, is expressed in the myogenic lineage during early mouse embryonic development. Gene Expr Patterns 9: 129–137. doi: 10.1016/j.gep.2008.12.002 19118645
    • (2009) Gene Expr Patterns , vol.9 , pp. 129-137
    • Mielcarek, M.1    Piotrowska, I.2    Schneider, A.3    Gunther, S.4    Braun, T.5
  • 39
    • 1342306306 scopus 로고    scopus 로고
    • VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation
    • Gunther S, Mielcarek M, Kruger M, Braun T, (2004) VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. Nucleic Acids Res 32: 791–802. 14762206
    • (2004) Nucleic Acids Res , vol.32 , pp. 791-802
    • Gunther, S.1    Mielcarek, M.2    Kruger, M.3    Braun, T.4
  • 40
    • 84892450038 scopus 로고    scopus 로고
    • p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin
    • Ehrnhoefer DE, Skotte NH, Ladha S, Nguyen YT, Qiu X, et al. (2014) p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin. Hum Mol Genet 23: 717–729. doi: 10.1093/hmg/ddt458 24070868
    • (2014) Hum Mol Genet , vol.23 , pp. 717-729
    • Ehrnhoefer, D.E.1    Skotte, N.H.2    Ladha, S.3    Nguyen, Y.T.4    Qiu, X.5
  • 41
    • 58249119457 scopus 로고    scopus 로고
    • The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity
    • Cohen TJ, Barrientos T, Hartman ZC, Garvey SM, Cox GA, et al. (2009) The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity. FASEB J 23: 99–106. doi: 10.1096/fj.08-115931 18780762
    • (2009) FASEB J , vol.23 , pp. 99-106
    • Cohen, T.J.1    Barrientos, T.2    Hartman, Z.C.3    Garvey, S.M.4    Cox, G.A.5
  • 42
    • 36348988617 scopus 로고    scopus 로고
    • The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming
    • Cohen TJ, Waddell DS, Barrientos T, Lu Z, Feng G, et al. (2007) The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming. J Biol Chem 282: 33752–33759. 17873280
    • (2007) J Biol Chem , vol.282 , pp. 33752-33759
    • Cohen, T.J.1    Waddell, D.S.2    Barrientos, T.3    Lu, Z.4    Feng, G.5
  • 43
    • 84891554347 scopus 로고    scopus 로고
    • miR-206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4
    • Winbanks CE, Beyer C, Hagg A, Qian H, Sepulveda PV, et al. (2013) miR-206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4. PLoS One 8: e73589. doi: 10.1371/journal.pone.0073589 24023888
    • (2013) PLoS One , vol.8 , pp. 73589
    • Winbanks, C.E.1    Beyer, C.2    Hagg, A.3    Qian, H.4    Sepulveda, P.V.5
  • 44
    • 84861807017 scopus 로고    scopus 로고
    • microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice
    • Liu N, Williams AH, Maxeiner JM, Bezprozvannaya S, Shelton JM, et al. (2012) microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. J Clin Invest 122: 2054–2065. doi: 10.1172/JCI62656 22546853
    • (2012) J Clin Invest , vol.122 , pp. 2054-2065
    • Liu, N.1    Williams, A.H.2    Maxeiner, J.M.3    Bezprozvannaya, S.4    Shelton, J.M.5
  • 45
    • 72149131804 scopus 로고    scopus 로고
    • MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice
    • Williams AH, Valdez G, Moresi V, Qi X, McAnally J, et al. (2009) MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science 326: 1549–1554. doi: 10.1126/science.1181046 20007902
    • (2009) Science , vol.326 , pp. 1549-1554
    • Williams, A.H.1    Valdez, G.2    Moresi, V.3    Qi, X.4    McAnally, J.5
  • 46
    • 84880960483 scopus 로고    scopus 로고
    • Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression
    • Bruneteau G, Simonet T, Bauche S, Mandjee N, Malfatti E, et al. (2013) Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression. Brain 136: 2359–2368. doi: 10.1093/brain/awt164 23824486
    • (2013) Brain , vol.136 , pp. 2359-2368
    • Bruneteau, G.1    Simonet, T.2    Bauche, S.3    Mandjee, N.4    Malfatti, E.5
  • 47
    • 84867132241 scopus 로고    scopus 로고
    • Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice
    • Bricceno KV, Sampognaro PJ, Van Meerbeke JP, Sumner CJ, Fischbeck KH, et al. (2012) Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice. Hum Mol Genet 21: 4448–4459. 22798624
    • (2012) Hum Mol Genet , vol.21 , pp. 4448-4459
    • Bricceno, K.V.1    Sampognaro, P.J.2    Van Meerbeke, J.P.3    Sumner, C.J.4    Fischbeck, K.H.5
  • 48
    • 84893142272 scopus 로고    scopus 로고
    • Signaling pathways controlling skeletal muscle mass
    • Egerman MA, Glass DJ, (2014) Signaling pathways controlling skeletal muscle mass. Crit Rev Biochem Mol Biol 49: 59–68. doi: 10.3109/10409238.2013.857291 24237131
    • (2014) Crit Rev Biochem Mol Biol , vol.49 , pp. 59-68
    • Egerman, M.A.1    Glass, D.J.2
  • 49
    • 33746328957 scopus 로고    scopus 로고
    • Signaling pathways in skeletal muscle remodeling
    • Bassel-Duby R, Olson EN, (2006) Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem 75: 19–37. 16756483
    • (2006) Annu Rev Biochem , vol.75 , pp. 19-37
    • Bassel-Duby, R.1    Olson, E.N.2
  • 50
    • 84897930723 scopus 로고    scopus 로고
    • Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways
    • Brooks NE, Myburgh KH, (2014) Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways. Front Physiol 5: 99. doi: 10.3389/fphys.2014.00099 24672488
    • (2014) Front Physiol , vol.5 , pp. 99
    • Brooks, N.E.1    Myburgh, K.H.2
  • 51
    • 10844273236 scopus 로고    scopus 로고
    • Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation
    • Ribchester RR, Thomson D, Wood NI, Hinks T, Gillingwater TH, et al. (2004) Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation. Eur J Neurosci 20: 3092–3114. 15579164
    • (2004) Eur J Neurosci , vol.20 , pp. 3092-3114
    • Ribchester, R.R.1    Thomson, D.2    Wood, N.I.3    Hinks, T.4    Gillingwater, T.H.5
  • 53
    • 80054760368 scopus 로고    scopus 로고
    • Fiber types in mammalian skeletal muscles
    • Schiaffino S, Reggiani C, (2011) Fiber types in mammalian skeletal muscles. Physiol Rev 91: 1447–1531. doi: 10.1152/physrev.00031.2010 22013216
    • (2011) Physiol Rev , vol.91 , pp. 1447-1531
    • Schiaffino, S.1    Reggiani, C.2
  • 54
    • 84878459469 scopus 로고    scopus 로고
    • Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction
    • Waters CW, Varuzhanyan G, Talmadge RJ, Voss AA, (2013) Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction. Proc Natl Acad Sci U S A 110: 9160–9165. doi: 10.1073/pnas.1220068110 23671115
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 9160-9165
    • Waters, C.W.1    Varuzhanyan, G.2    Talmadge, R.J.3    Voss, A.A.4
  • 55
    • 37349066159 scopus 로고    scopus 로고
    • Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the Huntington's disease mutation
    • Wade A, Jacobs P, Morton AJ, (2008) Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the Huntington's disease mutation. Brain Res 1188: 61–68. 18062944
    • (2008) Brain Res , vol.1188 , pp. 61-68
    • Wade, A.1    Jacobs, P.2    Morton, A.J.3
  • 56
    • 78751517878 scopus 로고    scopus 로고
    • Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease
    • Rozas JL, Gomez-Sanchez L, Tomas-Zapico C, Lucas JJ, Fernandez-Chacon R, (2011) Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease. J Neurosci 31: 1106–1113. doi: 10.1523/JNEUROSCI.2011-10.2011 21248135
    • (2011) J Neurosci , vol.31 , pp. 1106-1113
    • Rozas, J.L.1    Gomez-Sanchez, L.2    Tomas-Zapico, C.3    Lucas, J.J.4    Fernandez-Chacon, R.5
  • 57
    • 84879416006 scopus 로고    scopus 로고
    • Consistent neurodegeneration and its association with clinical progression in Huntington's disease: a coordinate-based meta-analysis
    • Dogan I, Eickhoff SB, Schulz JB, Shah NJ, Laird AR, et al. (2013) Consistent neurodegeneration and its association with clinical progression in Huntington's disease: a coordinate-based meta-analysis. Neurodegener Dis 12: 23–35. doi: 10.1159/000339528 22922585
    • (2013) Neurodegener Dis , vol.12 , pp. 23-35
    • Dogan, I.1    Eickhoff, S.B.2    Schulz, J.B.3    Shah, N.J.4    Laird, A.R.5
  • 58
    • 84895480605 scopus 로고    scopus 로고
    • A metabolic link to skeletal muscle wasting and regeneration
    • Koopman R, Ly CH, Ryall JG, (2014) A metabolic link to skeletal muscle wasting and regeneration. Front Physiol 5: 32. doi: 10.3389/fphys.2014.00032 24567722
    • (2014) Front Physiol , vol.5 , pp. 32
    • Koopman, R.1    Ly, C.H.2    Ryall, J.G.3
  • 59
    • 33750975898 scopus 로고    scopus 로고
    • Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects
    • Ciammola A, Sassone J, Alberti L, Meola G, Mancinelli E, et al. (2006) Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects. Cell Death Differ 13: 2068–2078. 16729030
    • (2006) Cell Death Differ , vol.13 , pp. 2068-2078
    • Ciammola, A.1    Sassone, J.2    Alberti, L.3    Meola, G.4    Mancinelli, E.5
  • 60
    • 84901290643 scopus 로고    scopus 로고
    • Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells
    • Ismailoglu I, Chen Q, Popowski M, Yang L, Gross SS, et al. (2014) Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells. Dev Biol 391: 230–240. doi: 10.1016/j.ydbio.2014.04.005 24780625
    • (2014) Dev Biol , vol.391 , pp. 230-240
    • Ismailoglu, I.1    Chen, Q.2    Popowski, M.3    Yang, L.4    Gross, S.S.5
  • 61
    • 80051970950 scopus 로고    scopus 로고
    • FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model
    • Schips TG, Wietelmann A, Hohn K, Schimanski S, Walther P, et al. (2011) FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model. Cardiovasc Res 91: 587–597. doi: 10.1093/cvr/cvr144 21628326
    • (2011) Cardiovasc Res , vol.91 , pp. 587-597
    • Schips, T.G.1    Wietelmann, A.2    Hohn, K.3    Schimanski, S.4    Walther, P.5
  • 62
    • 0141678246 scopus 로고    scopus 로고
    • Standardization and statistical approaches to therapeutic trials in the R6/2 mouse
    • Hockly E, Woodman B, Mahal A, Lewis CM, Bates G, (2003) Standardization and statistical approaches to therapeutic trials in the R6/2 mouse. Brain Res Bull 61: 469–479. 13679245
    • (2003) Brain Res Bull , vol.61 , pp. 469-479
    • Hockly, E.1    Woodman, B.2    Mahal, A.3    Lewis, C.M.4    Bates, G.5
  • 63
    • 82155182012 scopus 로고    scopus 로고
    • SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease
    • Mielcarek M, Benn CL, Franklin SA, Smith DL, Woodman B, et al. (2011) SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease. PLoS One 6: e27746. doi: 10.1371/journal.pone.0027746 22140466
    • (2011) PLoS One , vol.6 , pp. 27746
    • Mielcarek, M.1    Benn, C.L.2    Franklin, S.A.3    Smith, D.L.4    Woodman, B.5
  • 64
    • 84889031644 scopus 로고    scopus 로고
    • HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration
    • Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, et al. (2013) HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol 11: e1001717. doi: 10.1371/journal.pbio.1001717 24302884
    • (2013) PLoS Biol , vol.11 , pp. 1001717
    • Mielcarek, M.1    Landles, C.2    Weiss, A.3    Bradaia, A.4    Seredenina, T.5
  • 65
    • 84889000595 scopus 로고    scopus 로고
    • HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo
    • Mielcarek M, Seredenina T, Stokes MP, Osborne GF, Landles C, et al. (2013) HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo. PLoS One 8: e80849. doi: 10.1371/journal.pone.0080849 24278330
    • (2013) PLoS One , vol.8 , pp. 80849
    • Mielcarek, M.1    Seredenina, T.2    Stokes, M.P.3    Osborne, G.F.4    Landles, C.5
  • 66
    • 0025311410 scopus 로고
    • Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation
    • Smolenski RT, Lachno DR, Ledingham SJ, Yacoub MH, (1990) Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation. J Chromatogr 527: 414–420. 2387888
    • (1990) J Chromatogr , vol.527 , pp. 414-420
    • Smolenski, R.T.1    Lachno, D.R.2    Ledingham, S.J.3    Yacoub, M.H.4
  • 67
    • 13944271398 scopus 로고    scopus 로고
    • Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle
    • Soppa GK, Smolenski RT, Latif N, Yuen AH, Malik A, et al. (2005) Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle. Am J Physiol Heart Circ Physiol 288: H1468–H1476. 15528231
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. 1468-1476
    • Soppa, G.K.1    Smolenski, R.T.2    Latif, N.3    Yuen, A.H.4    Malik, A.5
  • 68
    • 80052303432 scopus 로고    scopus 로고
    • A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis
    • Acevedo-Arozena A, Kalmar B, Essa S, Ricketts T, Joyce P, et al. (2011) A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. Dis Model Mech 4: 686–700. doi: 10.1242/dmm.007237 21540242
    • (2011) Dis Model Mech , vol.4 , pp. 686-700
    • Acevedo-Arozena, A.1    Kalmar, B.2    Essa, S.3    Ricketts, T.4    Joyce, P.5
  • 69
    • 84864014087 scopus 로고    scopus 로고
    • Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS
    • Lu CH, Petzold A, Kalmar B, Dick J, Malaspina A, et al. (2012) Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS. PLoS One 7: e40998. doi: 10.1371/journal.pone.0040998 22815892
    • (2012) PLoS One , vol.7 , pp. 40998
    • Lu, C.H.1    Petzold, A.2    Kalmar, B.3    Dick, J.4    Malaspina, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.