-
2
-
-
0027432418
-
Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues
-
Strong TV, Tagle DA, Valdes JM, Elmer LW, Boehm K, et al. (1993) Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues. Nat Genet 5: 259–265. 8275091
-
(1993)
Nat Genet
, vol.5
, pp. 259-265
-
-
Strong, T.V.1
Tagle, D.A.2
Valdes, J.M.3
Elmer, L.W.4
Boehm, K.5
-
3
-
-
0027484673
-
Huntington's disease gene (IT15) is widely expressed in human and rat tissues
-
Li SH, Schilling G, Young WS, 3rdLi XJ, Margolis RL, et al. (1993) Huntington's disease gene (IT15) is widely expressed in human and rat tissues. Neuron 11: 985–993. 8240819
-
(1993)
Neuron
, vol.11
, pp. 985-993
-
-
Li, S.H.1
Schilling, G.2
Young, W.S.3
Li, X.J.4
Margolis, R.L.5
-
4
-
-
1242338856
-
Huntingtin-protein interactions and the pathogenesis of Huntington's disease
-
Li SH, Li XJ, (2004) Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet 20: 146–154. 15036808
-
(2004)
Trends Genet
, vol.20
, pp. 146-154
-
-
Li, S.H.1
Li, X.J.2
-
5
-
-
33744921670
-
Expression and characterization of full-length human huntingtin, an elongated HEAT repeat protein
-
Li W, Serpell LC, Carter WJ, Rubinsztein DC, Huntington JA, (2006) Expression and characterization of full-length human huntingtin, an elongated HEAT repeat protein. J Biol Chem 281: 15916–15922. 16595690
-
(2006)
J Biol Chem
, vol.281
, pp. 15916-15922
-
-
Li, W.1
Serpell, L.C.2
Carter, W.J.3
Rubinsztein, D.C.4
Huntington, J.A.5
-
6
-
-
0041656292
-
The hunt for huntingtin function: interaction partners tell many different stories
-
Harjes P, Wanker EE, (2003) The hunt for huntingtin function: interaction partners tell many different stories. Trends Biochem Sci 28: 425–433. 12932731
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 425-433
-
-
Harjes, P.1
Wanker, E.E.2
-
7
-
-
84993912315
-
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
-
Zeitlin S, Liu JP, Chapman DL, Papaioannou VE, Efstratiadis A, (1995) Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nat Genet 11: 155–163. 7550343
-
(1995)
Nat Genet
, vol.11
, pp. 155-163
-
-
Zeitlin, S.1
Liu, J.P.2
Chapman, D.L.3
Papaioannou, V.E.4
Efstratiadis, A.5
-
8
-
-
0033119123
-
Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology
-
Gutekunst CA, Li SH, Yi H, Mulroy JS, Kuemmerle S, et al. (1999) Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. J Neurosci 19: 2522–2534. 10087066
-
(1999)
J Neurosci
, vol.19
, pp. 2522-2534
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Mulroy, J.S.4
Kuemmerle, S.5
-
9
-
-
77649297870
-
Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease
-
Sathasivam K, Lane A, Legleiter J, Warley A, Woodman B, et al. (2010) Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease. Hum Mol Genet 19: 65–78. doi: 10.1093/hmg/ddp467 19825844
-
(2010)
Hum Mol Genet
, vol.19
, pp. 65-78
-
-
Sathasivam, K.1
Lane, A.2
Legleiter, J.3
Warley, A.4
Woodman, B.5
-
10
-
-
77950547661
-
Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease
-
Moffitt H, McPhail GD, Woodman B, Hobbs C, Bates GP, (2009) Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease. PLoS One 4: e8025. doi: 10.1371/journal.pone.0008025 19956633
-
(2009)
PLoS One
, vol.4
, pp. 8025
-
-
Moffitt, H.1
McPhail, G.D.2
Woodman, B.3
Hobbs, C.4
Bates, G.P.5
-
12
-
-
44449104300
-
Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure
-
Pattison JS, Sanbe A, Maloyan A, Osinska H, Klevitsky R, et al. (2008) Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure. Circulation 117: 2743–2751. doi: 10.1161/CIRCULATIONAHA.107.750232 18490523
-
(2008)
Circulation
, vol.117
, pp. 2743-2751
-
-
Pattison, J.S.1
Sanbe, A.2
Maloyan, A.3
Osinska, H.4
Klevitsky, R.5
-
13
-
-
84944718721
-
Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease
-
Mielcarek M, Inuabasi L, Bondulich MK, Muller T, Osborne GF, et al. (2014) Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease. PLoS Genet 10: e1004550. doi: 10.1371/journal.pgen.1004550 25101683
-
(2014)
PLoS Genet
, vol.10
, pp. 1004550
-
-
Mielcarek, M.1
Inuabasi, L.2
Bondulich, M.K.3
Muller, T.4
Osborne, G.F.5
-
14
-
-
84907484531
-
The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model
-
Mielcarek M, Bondulich MK, Inuabasi L, Franklin SA, Muller T, et al. (2014) The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model. PLoS One 9: e108961. doi: 10.1371/journal.pone.0108961 25268775
-
(2014)
PLoS One
, vol.9
, pp. 108961
-
-
Mielcarek, M.1
Bondulich, M.K.2
Inuabasi, L.3
Franklin, S.A.4
Muller, T.5
-
15
-
-
67650095269
-
Beyond the brain: widespread pathology in Huntington's disease
-
van der Burg JM, Bjorkqvist M, Brundin P, (2009) Beyond the brain: widespread pathology in Huntington's disease. Lancet Neurol 8: 765–774. doi: 10.1016/S1474-4422(09)70178-4 19608102
-
(2009)
Lancet Neurol
, vol.8
, pp. 765-774
-
-
van der Burg, J.M.1
Bjorkqvist, M.2
Brundin, P.3
-
16
-
-
84908384280
-
Skeletal muscle pathology in Huntington's disease
-
Zielonka D, Piotrowska I, Marcinkowski JT, Mielcarek M, (2014) Skeletal muscle pathology in Huntington's disease. Front Physiol 5:380: 1–5.
-
(2014)
Front Physiol
, vol.5
, Issue.380
, pp. 1-5
-
-
Zielonka, D.1
Piotrowska, I.2
Marcinkowski, J.T.3
Mielcarek, M.4
-
17
-
-
34748821960
-
Myopathy as a first symptom of Huntington's disease in a Marathon runner
-
Kosinski CM, Schlangen C, Gellerich FN, Gizatullina Z, Deschauer M, et al. (2007) Myopathy as a first symptom of Huntington's disease in a Marathon runner. Mov Disord 22: 1637–1640. 17534945
-
(2007)
Mov Disord
, vol.22
, pp. 1637-1640
-
-
Kosinski, C.M.1
Schlangen, C.2
Gellerich, F.N.3
Gizatullina, Z.4
Deschauer, M.5
-
18
-
-
0037101835
-
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
-
Luthi-Carter R, Hanson SA, Strand AD, Bergstrom DA, Chun W, et al. (2002) Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum Mol Genet 11: 1911–1926. 12165554
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1911-1926
-
-
Luthi-Carter, R.1
Hanson, S.A.2
Strand, A.D.3
Bergstrom, D.A.4
Chun, W.5
-
19
-
-
25844526181
-
Gene expression in Huntington's disease skeletal muscle: a potential biomarker
-
Strand AD, Aragaki AK, Shaw D, Bird T, Holton J, et al. (2005) Gene expression in Huntington's disease skeletal muscle: a potential biomarker. Hum Mol Genet 14: 1863–1876. 15888475
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1863-1876
-
-
Strand, A.D.1
Aragaki, A.K.2
Shaw, D.3
Bird, T.4
Holton, J.5
-
20
-
-
0033914747
-
Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy
-
Lodi R, Schapira AH, Manners D, Styles P, Wood NW, et al. (2000) Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy. Ann Neurol 48: 72–76. 10894218
-
(2000)
Ann Neurol
, vol.48
, pp. 72-76
-
-
Lodi, R.1
Schapira, A.H.2
Manners, D.3
Styles, P.4
Wood, N.W.5
-
21
-
-
22844440902
-
Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease
-
Saft C, Zange J, Andrich J, Muller K, Lindenberg K, et al. (2005) Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease. Mov Disord 20: 674–679. 15704211
-
(2005)
Mov Disord
, vol.20
, pp. 674-679
-
-
Saft, C.1
Zange, J.2
Andrich, J.3
Muller, K.4
Lindenberg, K.5
-
22
-
-
79951492653
-
Low anaerobic threshold and increased skeletal muscle lactate production in subjects with Huntington's disease
-
Ciammola A, Sassone J, Sciacco M, Mencacci NE, Ripolone M, et al. (2011) Low anaerobic threshold and increased skeletal muscle lactate production in subjects with Huntington's disease. Mov Disord 26: 130–137. doi: 10.1002/mds.23258 20931633
-
(2011)
Mov Disord
, vol.26
, pp. 130-137
-
-
Ciammola, A.1
Sassone, J.2
Sciacco, M.3
Mencacci, N.E.4
Ripolone, M.5
-
23
-
-
70349422148
-
Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease
-
Quintanilla RA, Johnson GV, (2009) Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease. Brain Res Bull 80: 242–247. doi: 10.1016/j.brainresbull.2009.07.010 19622387
-
(2009)
Brain Res Bull
, vol.80
, pp. 242-247
-
-
Quintanilla, R.A.1
Johnson, G.V.2
-
24
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J, Handschin C, Spiegelman BM, (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 1: 361–370. 16054085
-
(2005)
Cell Metab
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
25
-
-
84863011541
-
Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
-
Johri A, Calingasan NY, Hennessey TM, Sharma A, Yang L, et al. (2012) Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease. Hum Mol Genet 21: 1124–1137. doi: 10.1093/hmg/ddr541 22095692
-
(2012)
Hum Mol Genet
, vol.21
, pp. 1124-1137
-
-
Johri, A.1
Calingasan, N.Y.2
Hennessey, T.M.3
Sharma, A.4
Yang, L.5
-
26
-
-
27144524290
-
Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models
-
Fujimoto M, Takaki E, Hayashi T, Kitaura Y, Tanaka Y, et al. (2005) Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models. J Biol Chem 280: 34908–34916. 16051598
-
(2005)
J Biol Chem
, vol.280
, pp. 34908-34916
-
-
Fujimoto, M.1
Takaki, E.2
Hayashi, T.3
Kitaura, Y.4
Tanaka, Y.5
-
27
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, et al. (1996) Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87: 493–506. 8898202
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
-
28
-
-
0035862896
-
Neurological abnormalities in a knock-in mouse model of Huntington's disease
-
Lin CH, Tallaksen-Greene S, Chien WM, Cearley JA, Jackson WS, et al. (2001) Neurological abnormalities in a knock-in mouse model of Huntington's disease. Hum Mol Genet 10: 137–144. 11152661
-
(2001)
Hum Mol Genet
, vol.10
, pp. 137-144
-
-
Lin, C.H.1
Tallaksen-Greene, S.2
Chien, W.M.3
Cearley, J.A.4
Jackson, W.S.5
-
29
-
-
33847684865
-
The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes
-
Woodman B, Butler R, Landles C, Lupton MK, Tse J, et al. (2007) The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes. Brain Res Bull 72: 83–97. 17352931
-
(2007)
Brain Res Bull
, vol.72
, pp. 83-97
-
-
Woodman, B.1
Butler, R.2
Landles, C.3
Lupton, M.K.4
Tse, J.5
-
30
-
-
84873463075
-
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
-
Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, et al. (2013) Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Proc Natl Acad Sci U S A 110: 2366–2370. doi: 10.1073/pnas.1221891110 23341618
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 2366-2370
-
-
Sathasivam, K.1
Neueder, A.2
Gipson, T.A.3
Landles, C.4
Benjamin, A.C.5
-
31
-
-
0032919205
-
Formation of polyglutamine inclusions in non-CNS tissue
-
Sathasivam K, Hobbs C, Turmaine M, Mangiarini L, Mahal A, et al. (1999) Formation of polyglutamine inclusions in non-CNS tissue. Hum Mol Genet 8: 813–822. 10196370
-
(1999)
Hum Mol Genet
, vol.8
, pp. 813-822
-
-
Sathasivam, K.1
Hobbs, C.2
Turmaine, M.3
Mangiarini, L.4
Mahal, A.5
-
32
-
-
84875427900
-
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
-
Mitchell JC, McGoldrick P, Vance C, Hortobagyi T, Sreedharan J, et al. (2013) Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion. Acta Neuropathol 125: 273–288. doi: 10.1007/s00401-012-1043-z 22961620
-
(2013)
Acta Neuropathol
, vol.125
, pp. 273-288
-
-
Mitchell, J.C.1
McGoldrick, P.2
Vance, C.3
Hortobagyi, T.4
Sreedharan, J.5
-
33
-
-
61349179577
-
Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype
-
Tsika RW, Schramm C, Simmer G, Fitzsimons DP, Moss RL, et al. (2008) Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype. J Biol Chem 283: 36154–36167. doi: 10.1074/jbc.M807461200 18978355
-
(2008)
J Biol Chem
, vol.283
, pp. 36154-36167
-
-
Tsika, R.W.1
Schramm, C.2
Simmer, G.3
Fitzsimons, D.P.4
Moss, R.L.5
-
34
-
-
37549049708
-
MCAT elements and the TEF-1 family of transcription factors in muscle development and disease
-
Yoshida T, (2008) MCAT elements and the TEF-1 family of transcription factors in muscle development and disease. Arterioscler Thromb Vasc Biol 28: 8–17. 17962623
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 8-17
-
-
Yoshida, T.1
-
35
-
-
0042092011
-
Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions
-
Karasseva N, Tsika G, Ji J, Zhang A, Mao X, et al. (2003) Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions. Mol Cell Biol 23: 5143–5164. 12861002
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5143-5164
-
-
Karasseva, N.1
Tsika, G.2
Ji, J.3
Zhang, A.4
Mao, X.5
-
36
-
-
33644632444
-
Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway
-
Zhao P, Caretti G, Mitchell S, McKeehan WL, Boskey AL, et al. (2006) Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway. J Biol Chem 281: 429–438. 16267055
-
(2006)
J Biol Chem
, vol.281
, pp. 429-438
-
-
Zhao, P.1
Caretti, G.2
Mitchell, S.3
McKeehan, W.L.4
Boskey, A.L.5
-
37
-
-
1342342827
-
VITO-1, a novel vestigial related protein is predominantly expressed in the skeletal muscle lineage
-
Mielcarek M, Gunther S, Kruger M, Braun T, (2002) VITO-1, a novel vestigial related protein is predominantly expressed in the skeletal muscle lineage. Mech Dev 119 Suppl 1: S269–274. 14516696
-
(2002)
Mech Dev
, vol.119
, pp. 269-274
-
-
Mielcarek, M.1
Gunther, S.2
Kruger, M.3
Braun, T.4
-
38
-
-
58749098559
-
VITO-2, a new SID domain protein, is expressed in the myogenic lineage during early mouse embryonic development
-
Mielcarek M, Piotrowska I, Schneider A, Gunther S, Braun T, (2009) VITO-2, a new SID domain protein, is expressed in the myogenic lineage during early mouse embryonic development. Gene Expr Patterns 9: 129–137. doi: 10.1016/j.gep.2008.12.002 19118645
-
(2009)
Gene Expr Patterns
, vol.9
, pp. 129-137
-
-
Mielcarek, M.1
Piotrowska, I.2
Schneider, A.3
Gunther, S.4
Braun, T.5
-
39
-
-
1342306306
-
VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation
-
Gunther S, Mielcarek M, Kruger M, Braun T, (2004) VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. Nucleic Acids Res 32: 791–802. 14762206
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 791-802
-
-
Gunther, S.1
Mielcarek, M.2
Kruger, M.3
Braun, T.4
-
40
-
-
84892450038
-
p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin
-
Ehrnhoefer DE, Skotte NH, Ladha S, Nguyen YT, Qiu X, et al. (2014) p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin. Hum Mol Genet 23: 717–729. doi: 10.1093/hmg/ddt458 24070868
-
(2014)
Hum Mol Genet
, vol.23
, pp. 717-729
-
-
Ehrnhoefer, D.E.1
Skotte, N.H.2
Ladha, S.3
Nguyen, Y.T.4
Qiu, X.5
-
41
-
-
58249119457
-
The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity
-
Cohen TJ, Barrientos T, Hartman ZC, Garvey SM, Cox GA, et al. (2009) The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity. FASEB J 23: 99–106. doi: 10.1096/fj.08-115931 18780762
-
(2009)
FASEB J
, vol.23
, pp. 99-106
-
-
Cohen, T.J.1
Barrientos, T.2
Hartman, Z.C.3
Garvey, S.M.4
Cox, G.A.5
-
42
-
-
36348988617
-
The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming
-
Cohen TJ, Waddell DS, Barrientos T, Lu Z, Feng G, et al. (2007) The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming. J Biol Chem 282: 33752–33759. 17873280
-
(2007)
J Biol Chem
, vol.282
, pp. 33752-33759
-
-
Cohen, T.J.1
Waddell, D.S.2
Barrientos, T.3
Lu, Z.4
Feng, G.5
-
43
-
-
84891554347
-
miR-206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4
-
Winbanks CE, Beyer C, Hagg A, Qian H, Sepulveda PV, et al. (2013) miR-206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4. PLoS One 8: e73589. doi: 10.1371/journal.pone.0073589 24023888
-
(2013)
PLoS One
, vol.8
, pp. 73589
-
-
Winbanks, C.E.1
Beyer, C.2
Hagg, A.3
Qian, H.4
Sepulveda, P.V.5
-
44
-
-
84861807017
-
microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice
-
Liu N, Williams AH, Maxeiner JM, Bezprozvannaya S, Shelton JM, et al. (2012) microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. J Clin Invest 122: 2054–2065. doi: 10.1172/JCI62656 22546853
-
(2012)
J Clin Invest
, vol.122
, pp. 2054-2065
-
-
Liu, N.1
Williams, A.H.2
Maxeiner, J.M.3
Bezprozvannaya, S.4
Shelton, J.M.5
-
45
-
-
72149131804
-
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice
-
Williams AH, Valdez G, Moresi V, Qi X, McAnally J, et al. (2009) MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science 326: 1549–1554. doi: 10.1126/science.1181046 20007902
-
(2009)
Science
, vol.326
, pp. 1549-1554
-
-
Williams, A.H.1
Valdez, G.2
Moresi, V.3
Qi, X.4
McAnally, J.5
-
46
-
-
84880960483
-
Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression
-
Bruneteau G, Simonet T, Bauche S, Mandjee N, Malfatti E, et al. (2013) Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression. Brain 136: 2359–2368. doi: 10.1093/brain/awt164 23824486
-
(2013)
Brain
, vol.136
, pp. 2359-2368
-
-
Bruneteau, G.1
Simonet, T.2
Bauche, S.3
Mandjee, N.4
Malfatti, E.5
-
47
-
-
84867132241
-
Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice
-
Bricceno KV, Sampognaro PJ, Van Meerbeke JP, Sumner CJ, Fischbeck KH, et al. (2012) Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice. Hum Mol Genet 21: 4448–4459. 22798624
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4448-4459
-
-
Bricceno, K.V.1
Sampognaro, P.J.2
Van Meerbeke, J.P.3
Sumner, C.J.4
Fischbeck, K.H.5
-
48
-
-
84893142272
-
Signaling pathways controlling skeletal muscle mass
-
Egerman MA, Glass DJ, (2014) Signaling pathways controlling skeletal muscle mass. Crit Rev Biochem Mol Biol 49: 59–68. doi: 10.3109/10409238.2013.857291 24237131
-
(2014)
Crit Rev Biochem Mol Biol
, vol.49
, pp. 59-68
-
-
Egerman, M.A.1
Glass, D.J.2
-
49
-
-
33746328957
-
Signaling pathways in skeletal muscle remodeling
-
Bassel-Duby R, Olson EN, (2006) Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem 75: 19–37. 16756483
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 19-37
-
-
Bassel-Duby, R.1
Olson, E.N.2
-
50
-
-
84897930723
-
Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways
-
Brooks NE, Myburgh KH, (2014) Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways. Front Physiol 5: 99. doi: 10.3389/fphys.2014.00099 24672488
-
(2014)
Front Physiol
, vol.5
, pp. 99
-
-
Brooks, N.E.1
Myburgh, K.H.2
-
51
-
-
10844273236
-
Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation
-
Ribchester RR, Thomson D, Wood NI, Hinks T, Gillingwater TH, et al. (2004) Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation. Eur J Neurosci 20: 3092–3114. 15579164
-
(2004)
Eur J Neurosci
, vol.20
, pp. 3092-3114
-
-
Ribchester, R.R.1
Thomson, D.2
Wood, N.I.3
Hinks, T.4
Gillingwater, T.H.5
-
52
-
-
84885174553
-
Muscle type and fiber type specificity in muscle wasting
-
Ciciliot S, Rossi AC, Dyar KA, Blaauw B, Schiaffino S, (2013) Muscle type and fiber type specificity in muscle wasting. Int J Biochem Cell Biol 45: 2191–2199. doi: 10.1016/j.biocel.2013.05.016 23702032
-
(2013)
Int J Biochem Cell Biol
, vol.45
, pp. 2191-2199
-
-
Ciciliot, S.1
Rossi, A.C.2
Dyar, K.A.3
Blaauw, B.4
Schiaffino, S.5
-
53
-
-
80054760368
-
Fiber types in mammalian skeletal muscles
-
Schiaffino S, Reggiani C, (2011) Fiber types in mammalian skeletal muscles. Physiol Rev 91: 1447–1531. doi: 10.1152/physrev.00031.2010 22013216
-
(2011)
Physiol Rev
, vol.91
, pp. 1447-1531
-
-
Schiaffino, S.1
Reggiani, C.2
-
54
-
-
84878459469
-
Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction
-
Waters CW, Varuzhanyan G, Talmadge RJ, Voss AA, (2013) Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction. Proc Natl Acad Sci U S A 110: 9160–9165. doi: 10.1073/pnas.1220068110 23671115
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 9160-9165
-
-
Waters, C.W.1
Varuzhanyan, G.2
Talmadge, R.J.3
Voss, A.A.4
-
55
-
-
37349066159
-
Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the Huntington's disease mutation
-
Wade A, Jacobs P, Morton AJ, (2008) Atrophy and degeneration in sciatic nerve of presymptomatic mice carrying the Huntington's disease mutation. Brain Res 1188: 61–68. 18062944
-
(2008)
Brain Res
, vol.1188
, pp. 61-68
-
-
Wade, A.1
Jacobs, P.2
Morton, A.J.3
-
56
-
-
78751517878
-
Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease
-
Rozas JL, Gomez-Sanchez L, Tomas-Zapico C, Lucas JJ, Fernandez-Chacon R, (2011) Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease. J Neurosci 31: 1106–1113. doi: 10.1523/JNEUROSCI.2011-10.2011 21248135
-
(2011)
J Neurosci
, vol.31
, pp. 1106-1113
-
-
Rozas, J.L.1
Gomez-Sanchez, L.2
Tomas-Zapico, C.3
Lucas, J.J.4
Fernandez-Chacon, R.5
-
57
-
-
84879416006
-
Consistent neurodegeneration and its association with clinical progression in Huntington's disease: a coordinate-based meta-analysis
-
Dogan I, Eickhoff SB, Schulz JB, Shah NJ, Laird AR, et al. (2013) Consistent neurodegeneration and its association with clinical progression in Huntington's disease: a coordinate-based meta-analysis. Neurodegener Dis 12: 23–35. doi: 10.1159/000339528 22922585
-
(2013)
Neurodegener Dis
, vol.12
, pp. 23-35
-
-
Dogan, I.1
Eickhoff, S.B.2
Schulz, J.B.3
Shah, N.J.4
Laird, A.R.5
-
58
-
-
84895480605
-
A metabolic link to skeletal muscle wasting and regeneration
-
Koopman R, Ly CH, Ryall JG, (2014) A metabolic link to skeletal muscle wasting and regeneration. Front Physiol 5: 32. doi: 10.3389/fphys.2014.00032 24567722
-
(2014)
Front Physiol
, vol.5
, pp. 32
-
-
Koopman, R.1
Ly, C.H.2
Ryall, J.G.3
-
59
-
-
33750975898
-
Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects
-
Ciammola A, Sassone J, Alberti L, Meola G, Mancinelli E, et al. (2006) Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects. Cell Death Differ 13: 2068–2078. 16729030
-
(2006)
Cell Death Differ
, vol.13
, pp. 2068-2078
-
-
Ciammola, A.1
Sassone, J.2
Alberti, L.3
Meola, G.4
Mancinelli, E.5
-
60
-
-
84901290643
-
Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells
-
Ismailoglu I, Chen Q, Popowski M, Yang L, Gross SS, et al. (2014) Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells. Dev Biol 391: 230–240. doi: 10.1016/j.ydbio.2014.04.005 24780625
-
(2014)
Dev Biol
, vol.391
, pp. 230-240
-
-
Ismailoglu, I.1
Chen, Q.2
Popowski, M.3
Yang, L.4
Gross, S.S.5
-
61
-
-
80051970950
-
FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model
-
Schips TG, Wietelmann A, Hohn K, Schimanski S, Walther P, et al. (2011) FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model. Cardiovasc Res 91: 587–597. doi: 10.1093/cvr/cvr144 21628326
-
(2011)
Cardiovasc Res
, vol.91
, pp. 587-597
-
-
Schips, T.G.1
Wietelmann, A.2
Hohn, K.3
Schimanski, S.4
Walther, P.5
-
62
-
-
0141678246
-
Standardization and statistical approaches to therapeutic trials in the R6/2 mouse
-
Hockly E, Woodman B, Mahal A, Lewis CM, Bates G, (2003) Standardization and statistical approaches to therapeutic trials in the R6/2 mouse. Brain Res Bull 61: 469–479. 13679245
-
(2003)
Brain Res Bull
, vol.61
, pp. 469-479
-
-
Hockly, E.1
Woodman, B.2
Mahal, A.3
Lewis, C.M.4
Bates, G.5
-
63
-
-
82155182012
-
SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease
-
Mielcarek M, Benn CL, Franklin SA, Smith DL, Woodman B, et al. (2011) SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease. PLoS One 6: e27746. doi: 10.1371/journal.pone.0027746 22140466
-
(2011)
PLoS One
, vol.6
, pp. 27746
-
-
Mielcarek, M.1
Benn, C.L.2
Franklin, S.A.3
Smith, D.L.4
Woodman, B.5
-
64
-
-
84889031644
-
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration
-
Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, et al. (2013) HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol 11: e1001717. doi: 10.1371/journal.pbio.1001717 24302884
-
(2013)
PLoS Biol
, vol.11
, pp. 1001717
-
-
Mielcarek, M.1
Landles, C.2
Weiss, A.3
Bradaia, A.4
Seredenina, T.5
-
65
-
-
84889000595
-
HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo
-
Mielcarek M, Seredenina T, Stokes MP, Osborne GF, Landles C, et al. (2013) HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo. PLoS One 8: e80849. doi: 10.1371/journal.pone.0080849 24278330
-
(2013)
PLoS One
, vol.8
, pp. 80849
-
-
Mielcarek, M.1
Seredenina, T.2
Stokes, M.P.3
Osborne, G.F.4
Landles, C.5
-
66
-
-
0025311410
-
Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation
-
Smolenski RT, Lachno DR, Ledingham SJ, Yacoub MH, (1990) Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation. J Chromatogr 527: 414–420. 2387888
-
(1990)
J Chromatogr
, vol.527
, pp. 414-420
-
-
Smolenski, R.T.1
Lachno, D.R.2
Ledingham, S.J.3
Yacoub, M.H.4
-
67
-
-
13944271398
-
Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle
-
Soppa GK, Smolenski RT, Latif N, Yuen AH, Malik A, et al. (2005) Effects of chronic administration of clenbuterol on function and metabolism of adult rat cardiac muscle. Am J Physiol Heart Circ Physiol 288: H1468–H1476. 15528231
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
, pp. 1468-1476
-
-
Soppa, G.K.1
Smolenski, R.T.2
Latif, N.3
Yuen, A.H.4
Malik, A.5
-
68
-
-
80052303432
-
A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis
-
Acevedo-Arozena A, Kalmar B, Essa S, Ricketts T, Joyce P, et al. (2011) A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. Dis Model Mech 4: 686–700. doi: 10.1242/dmm.007237 21540242
-
(2011)
Dis Model Mech
, vol.4
, pp. 686-700
-
-
Acevedo-Arozena, A.1
Kalmar, B.2
Essa, S.3
Ricketts, T.4
Joyce, P.5
-
69
-
-
84864014087
-
Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS
-
Lu CH, Petzold A, Kalmar B, Dick J, Malaspina A, et al. (2012) Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS. PLoS One 7: e40998. doi: 10.1371/journal.pone.0040998 22815892
-
(2012)
PLoS One
, vol.7
, pp. 40998
-
-
Lu, C.H.1
Petzold, A.2
Kalmar, B.3
Dick, J.4
Malaspina, A.5
|