Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 22, 2013, Pages 9160-9165

  Waters, Christopher W ^a   Varuzhanyan, Grigor ^a   Talmadge, Robert J ^a   Voss, Andrew A ^a  

^a CALIFORNIA STATE POLYTECHNIC UNIVERSITY   (United States)

Author keywords

Channelopathy; Electrophysiology; Myopathy; Myotonia; Trinucleotide Repeat

Indexed keywords

CHLORIDE CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL; MESSENGER RNA; POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CONDUCTANCE; ELECTROPHYSIOLOGY; EX VIVO STUDY; EXCITABILITY; FEMALE; HUNTINGTON CHOREA; MOUSE; MUSCLE ACTION POTENTIAL; MUSCLE SPASM; NONHUMAN; POTASSIUM CHANNELOPATHY; PRIORITY JOURNAL; SKELETAL MUSCLE;

CHANNELOPATHY; ELECTROPHYSIOLOGY; MYOPATHY; MYOTONIA; TRINUCLEOTIDE REPEAT;

ACTION POTENTIALS; ANIMALS; CHANNELOPATHIES; CHLORIDE CHANNELS; ELECTRIC IMPEDANCE; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS MUSCULUS;

EID: 84878459469     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1220068110     Document Type: Article

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