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Volumn 35, Issue 46, 2014, Pages 3258-3266

Mitochondrial injury and dysfunction in hypertension-induced cardiac damage

Author keywords

Blood pressure; Hypertension; Mitochondria

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; CALCIUM; CYCLOSPORIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MESSENGER RNA; MITOCHONDRIAL DNA; MITOFUSIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; VALSARTAN;

EID: 84926152755     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehu436     Document Type: Review
Times cited : (71)

References (86)
  • 2
    • 33846022731 scopus 로고    scopus 로고
    • Mitochondrial disease-its impact, etiology, and pathology
    • McFarland R, Taylor RW, Turnbull DM. Mitochondrial disease-its impact, etiology, and pathology. Curr Top Dev Biol 2007; 77: 113-155.
    • (2007) Curr Top Dev Biol , vol.77 , pp. 113-155
    • McFarland, R.1    Taylor, R.W.2    Turnbull, D.M.3
  • 3
    • 4043086952 scopus 로고    scopus 로고
    • Mitochondria in health and disease: Perspectives on a new mitochondrial biology
    • Duchen MR. Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol Aspects Med 2004; 25: 365-451.
    • (2004) Mol Aspects Med , vol.25 , pp. 365-451
    • Duchen, M.R.1
  • 4
    • 30844433781 scopus 로고    scopus 로고
    • Mitochondrial function, energy expenditure, aging and insulin resistance
    • Spec No 2
    • Ritz P, Berrut G. Mitochondrial function, energy expenditure, aging and insulin resistance. Diabetes Metab 2005; 31(Spec No 2): 5S67-65S73.
    • (2005) Diabetes Metab , vol.31 , pp. 5S67-65S73
    • Ritz, P.1    Berrut, G.2
  • 6
    • 0034235229 scopus 로고    scopus 로고
    • The internal structure of mitochondria
    • Frey TG, Mannella CA. The internal structure of mitochondria. Trends Biochem Sci 2000; 25: 319-324.
    • (2000) Trends Biochem Sci , vol.25 , pp. 319-324
    • Frey, T.G.1    Mannella, C.A.2
  • 7
    • 78651287877 scopus 로고    scopus 로고
    • Making heads or tails of phospholipids in mitochondria
    • Osman C, Voelker DR, Langer T. Making heads or tails of phospholipids in mitochondria. J Cell Biol 2011; 192: 7-16.
    • (2011) J Cell Biol , vol.192 , pp. 7-16
    • Osman, C.1    Voelker, D.R.2    Langer, T.3
  • 8
    • 1642341366 scopus 로고    scopus 로고
    • Mitochondriopathies
    • Finsterer J. Mitochondriopathies. Eur J Neurol 2004; 11: 163-186.
    • (2004) Eur J Neurol , vol.11 , pp. 163-186
    • Finsterer, J.1
  • 9
    • 0037029129 scopus 로고    scopus 로고
    • Reactive oxygen species affect mitochondrial electron transport complex i activity through oxidative cardiolipin damage
    • Paradies G, Petrosillo G, Pistolese M, Ruggiero FM. Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage. Gene 2002; 286: 135-141.
    • (2002) Gene , vol.286 , pp. 135-141
    • Paradies, G.1    Petrosillo, G.2    Pistolese, M.3    Ruggiero, F.M.4
  • 10
    • 0008724863 scopus 로고    scopus 로고
    • Reactive oxygen species generated by the mitochondrial respiratory chain affect the complex iii activity via cardiolipin peroxidation in beef-heart submitochondrial particles
    • Paradies G, Petrosillo G, Pistolese M, Ruggiero FM. Reactive oxygen species generated by the mitochondrial respiratory chain affect the complex III activity via cardiolipin peroxidation in beef-heart submitochondrial particles. Mitochondrion 2001; 1: 151-159.
    • (2001) Mitochondrion , vol.1 , pp. 151-159
    • Paradies, G.1    Petrosillo, G.2    Pistolese, M.3    Ruggiero, F.M.4
  • 11
    • 0035914342 scopus 로고    scopus 로고
    • Subcellular distribution of superoxide dismutases (sod) in rat liver: Cu, zn-sod in mitochondria
    • Okado-Matsumoto A, Fridovich I. Subcellular distribution of superoxide dismutases (sod) in rat liver: Cu, Zn-SOD in mitochondria. J Biol Chem 2001; 276: 38388-38393.
    • (2001) J Biol Chem , vol.276 , pp. 38388-38393
    • Okado-Matsumoto, A.1    Fridovich, I.2
  • 12
    • 79952339999 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in kidney disease
    • Weinberg JM. Mitochondrial biogenesis in kidney disease. J Am Soc Nephrol 2011; 22: 431-436.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 431-436
    • Weinberg, J.M.1
  • 13
    • 84887387419 scopus 로고    scopus 로고
    • After the banquet: Mitochondrial biogenesis, mitophagy, and cell survival
    • Zhu J, Wang KZ, Chu CT. After the banquet: mitochondrial biogenesis, mitophagy, and cell survival. Autophagy 2013; 9: 1663-1676.
    • (2013) Autophagy , vol.9 , pp. 1663-1676
    • Zhu, J.1    Wang, K.Z.2    Chu, C.T.3
  • 14
    • 84875753723 scopus 로고    scopus 로고
    • Mitochondrial dynamics: Regulatory mechanisms and emerging role in renal pathophysiology
    • Zhan M, Brooks C, Liu F, Sun L, Dong Z. Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology. Kidney Int 2013; 83: 568-581.
    • (2013) Kidney Int , vol.83 , pp. 568-581
    • Zhan, M.1    Brooks, C.2    Liu, F.3    Sun, L.4    Dong, Z.5
  • 15
    • 84889242417 scopus 로고    scopus 로고
    • Mitochondrial dynamics-mitochondrial fission and fusion in human diseases
    • Archer SL. Mitochondrial dynamics-mitochondrial fission and fusion in human diseases. N Engl J Med 2013; 369: 2236-2251.
    • (2013) N Engl J Med , vol.369 , pp. 2236-2251
    • Archer, S.L.1
  • 16
    • 84898622228 scopus 로고    scopus 로고
    • Musical chairs during mitophagy
    • Dengjel J, Abeliovich H. Musical chairs during mitophagy. Autophagy 2014; 10: 706-707.
    • (2014) Autophagy , vol.10 , pp. 706-707
    • Dengjel, J.1    Abeliovich, H.2
  • 17
    • 70349230846 scopus 로고    scopus 로고
    • Impaired atp turnover and adp supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts
    • Hickey AJ, Chai CC, Choong SY, de Freitas Costa S, Skea GL, Phillips AR, Cooper GJ. Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts. Am J Physiol Cell Physiol 2009; 297: C766-C774.
    • (2009) Am J Physiol Cell Physiol , vol.297 , pp. C766-C774
    • Hickey, A.J.1    Chai, C.C.2    Choong, S.Y.3    De Freitas Costa, S.4    Skea, G.L.5    Phillips, A.R.6    Cooper, G.J.7
  • 19
    • 0037440107 scopus 로고    scopus 로고
    • Reduced contraction strength with increased intracellular [ca2+] in left ventricular trabeculae from failing rat hearts
    • Ward M-L, Pope AJ, Loiselle DS, Cannell MB. Reduced contraction strength with increased intracellular [Ca2+] in left ventricular trabeculae from failing rat hearts. J Physiol 2003; 546: 537-550.
    • (2003) J Physiol , vol.546 , pp. 537-550
    • Ward, M.-L.1    Pope, A.J.2    Loiselle, D.S.3    Cannell, M.B.4
  • 20
    • 36949006516 scopus 로고    scopus 로고
    • The pparalpha-pgc-1alpha axis controls cardiac energy metabolism in healthy and diseased myocardium
    • Duncan JG, Finck BN. The PPARalpha-PGC-1alpha axis controls cardiac energy metabolism in healthy and diseased myocardium. PPAR Res 2008; 2008: 253817.
    • (2008) PPAR Res , vol.2008 , pp. 253817
    • Duncan, J.G.1    Finck, B.N.2
  • 21
    • 84856109625 scopus 로고    scopus 로고
    • Mitochondrial fusion is essential for organelle function and cardiac homeostasis
    • Chen Y, Liu Y, Dorn GW II. Mitochondrial fusion is essential for organelle function and cardiac homeostasis. Circ Res 2011; 109: 1327-1331.
    • (2011) Circ Res , vol.109 , pp. 1327-1331
    • Chen, Y.1    Liu, Y.2    Dorn, G.W.I.I.3
  • 22
  • 23
    • 84905132634 scopus 로고    scopus 로고
    • Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension
    • Eirin A, Williams BJ, Ebrahimi B, Zhang X, Crane JA, Lerman A, Textor SC, Lerman LO. Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension. J Hypertens 2014; 32: 154-165.
    • (2014) J Hypertens , vol.32 , pp. 154-165
    • Eirin, A.1    Williams, B.J.2    Ebrahimi, B.3    Zhang, X.4    Crane, J.A.5    Lerman, A.6    Textor, S.C.7    Lerman, L.O.8
  • 24
    • 84895074770 scopus 로고    scopus 로고
    • Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat
    • Tang Y, Mi C, Liu J, Gao F, Long J. Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat. Cardiovasc Pathol 2014; 23: 101-106.
    • (2014) Cardiovasc Pathol , vol.23 , pp. 101-106
    • Tang, Y.1    Mi, C.2    Liu, J.3    Gao, F.4    Long, J.5
  • 27
    • 0035725015 scopus 로고    scopus 로고
    • Nadh/nadph oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat
    • Beswick RA, Dorrance AM, Leite R, Webb RC. NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat. Hypertension 2001; 38: 1107-1111.
    • (2001) Hypertension , vol.38 , pp. 1107-1111
    • Beswick, R.A.1    Dorrance, A.M.2    Leite, R.3    Webb, R.C.4
  • 30
    • 16544383188 scopus 로고    scopus 로고
    • Mechanical stretch induces mitochondria-dependent apoptosis in neonatal rat cardiomyocytes and g2/m accumulation in cardiac fibroblasts
    • Liao XD, Wang XH, Jin HJ, Chen LY, Chen Q. Mechanical stretch induces mitochondria-dependent apoptosis in neonatal rat cardiomyocytes and G2/m accumulation in cardiac fibroblasts. Cell Res 2004; 14: 16-26.
    • (2004) Cell Res , vol.14 , pp. 16-26
    • Liao, X.D.1    Wang, X.H.2    Jin, H.J.3    Chen, L.Y.4    Chen, Q.5
  • 33
    • 0033535974 scopus 로고    scopus 로고
    • Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis
    • von Harsdorf R, Li PF, Dietz R. Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation 1999; 99: 2934-2941.
    • (1999) Circulation , vol.99 , pp. 2934-2941
    • Von Harsdorf, R.1    Li, P.F.2    Dietz, R.3
  • 35
    • 84879951018 scopus 로고    scopus 로고
    • Changes in cardiac mitochondrial aldehyde dehydrogenase 2 activity in relation to oxidative stress and inflammatory injury in diabetic rats
    • Wang H-J, Kang P-F, Wu W-J, Tang Y, Pan Q-Q, Ye H-W, Tang B, Li Z-H, Gao Q. Changes in cardiac mitochondrial aldehyde dehydrogenase 2 activity in relation to oxidative stress and inflammatory injury in diabetic rats. Mol Med Rep 2013; 8: 686-690.
    • (2013) Mol Med Rep , vol.8 , pp. 686-690
    • Wang, H.-J.1    Kang, P.-F.2    Wu, W.-J.3    Tang, Y.4    Pan, Q.-Q.5    Ye, H.-W.6    Tang, B.7    Li, Z.-H.8    Gao, Q.9
  • 37
    • 84900299510 scopus 로고    scopus 로고
    • Mitochondrial damage-Associated molecular patterns and vascular function
    • Working Group on Di C.D.
    • Wenceslau CF, McCarthy CG, Szasz T, Spitler K, Goulopoulou S, Webb RC. Working Group on Di CD. Mitochondrial damage-Associated molecular patterns and vascular function. Eur Heart J 2014; 35: 1172-1177.
    • (2014) Eur Heart J , vol.35 , pp. 1172-1177
    • Wenceslau, C.F.1    McCarthy, C.G.2    Szasz, T.3    Spitler, K.4    Goulopoulou, S.5    Webb, R.C.6
  • 42
    • 84876347779 scopus 로고    scopus 로고
    • Mitochondria and endothelial function
    • Kluge MA, Fetterman JL, Vita JA. Mitochondria and endothelial function. Circ Res 2013; 112: 1171-1188.
    • (2013) Circ Res , vol.112 , pp. 1171-1188
    • Kluge, M.A.1    Fetterman, J.L.2    Vita, J.A.3
  • 44
    • 84898917380 scopus 로고    scopus 로고
    • Arginase i enhances atherosclerotic plaque stabilization by inhibiting inflammation and promoting smooth muscle cell proliferation
    • Wang XP, Zhang W, Liu XQ, Wang WK, Yan F, Dong WQ, Zhang Y, Zhang MX. Arginase i enhances atherosclerotic plaque stabilization by inhibiting inflammation and promoting smooth muscle cell proliferation. Eur Heart J 2014; 35: 911-919.
    • (2014) Eur Heart J , vol.35 , pp. 911-919
    • Wang, X.P.1    Zhang, W.2    Liu, X.Q.3    Wang, W.K.4    Yan, F.5    Dong, W.Q.6    Zhang, Y.7    Zhang, M.X.8
  • 50
    • 0037326196 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor-gamma coactivator 1 alpha (pgc-1 alpha): Transcriptional coactivator and metabolic regulator
    • Puigserver P, Spiegelman BM. Peroxisome proliferator-Activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr Rev 2003; 24: 78-90.
    • (2003) Endocr Rev , vol.24 , pp. 78-90
    • Puigserver, P.1    Spiegelman, B.M.2
  • 51
    • 84879240043 scopus 로고    scopus 로고
    • Potential role of bnip3 in cardiac remodeling, myocardial stiffness, and endoplasmic reticulum: Mitochondrial calcium homeostasis in diastolic and systolic heart failure
    • Chaanine AH, Gordon RE, Kohlbrenner E, Benard L, Jeong D, Hajjar RJ. Potential role of BNIP3 in cardiac remodeling, myocardial stiffness, and endoplasmic reticulum: mitochondrial calcium homeostasis in diastolic and systolic heart failure. Circ Heart Fail 2013; 6: 572-583.
    • (2013) Circ Heart Fail , vol.6 , pp. 572-583
    • Chaanine, A.H.1    Gordon, R.E.2    Kohlbrenner, E.3    Benard, L.4    Jeong, D.5    Hajjar, R.J.6
  • 52
    • 0032807973 scopus 로고    scopus 로고
    • A mitochondrial cytochrome b mutation but no mutations of nuclearly encoded subunits in ubiquinol cytochrome c reductase (complex iii) deficiency
    • Valnot I, Kassis J, Chretien D, de Lonlay P, Parfait B, Munnich A, Kachaner J, Rustin P, Rotig A. A mitochondrial cytochrome b mutation but no mutations of nuclearly encoded subunits in ubiquinol cytochrome c reductase (complex III) deficiency. Hum Genet 1999; 104: 460-466.
    • (1999) Hum Genet , vol.104 , pp. 460-466
    • Valnot, I.1    Kassis, J.2    Chretien, D.3    De Lonlay, P.4    Parfait, B.5    Munnich, A.6    Kachaner, J.7    Rustin, P.8    Rotig, A.9
  • 54
    • 66049143421 scopus 로고    scopus 로고
    • Cloning, expression andmutation of mitochondrialatpase gene of hypertensive patients and rats
    • Zhou L, Wang DF, Zhang GY, Li HN, Zhang PP, Zhao XT, Gu JR, Liew CC. Cloning, expression andmutation of mitochondrialATPase gene of hypertensive patients and rats. ACTA 1999; 21: 729-732.
    • (1999) ACTA , vol.21 , pp. 729-732
    • Zhou, L.1    Wang, D.F.2    Zhang, G.Y.3    Li, H.N.4    Zhang, P.P.5    Zhao, X.T.6    Gu, J.R.7    Liew, C.C.8
  • 55
    • 84868209632 scopus 로고    scopus 로고
    • New insights on molecular mechanisms of renal aging
    • Schmitt R, Melk A. New insights on molecular mechanisms of renal aging. Am J Transplant 2012; 12: 2892-2900.
    • (2012) Am J Transplant , vol.12 , pp. 2892-2900
    • Schmitt, R.1    Melk, A.2
  • 56
    • 84903379646 scopus 로고    scopus 로고
    • Salt-sensitive hypertension in mitochondrial superoxide dismutase deficiency is associated with intra-renal oxidative stress and inflammation
    • Jin K, Vaziri ND. Salt-sensitive hypertension in mitochondrial superoxide dismutase deficiency is associated with intra-renal oxidative stress and inflammation. Clin Exp Nephrol 2013; 18: 445-452.
    • (2013) Clin Exp Nephrol , vol.18 , pp. 445-452
    • Jin, K.1    Vaziri, N.D.2
  • 58
    • 84865819868 scopus 로고    scopus 로고
    • Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb ofhenle in the dahl salt-sensitive rat
    • Zheleznova NN, Yang C, Ryan RP, Halligan BD, Liang M, Greene AS, Cowley AWJr. Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb ofHenle in the Dahl salt-sensitive rat. Physiol Genomics 2012; 44: 829-842.
    • (2012) Physiol Genomics , vol.44 , pp. 829-842
    • Zheleznova, N.N.1    Yang, C.2    Ryan, R.P.3    Halligan, B.D.4    Liang, M.5    Greene, A.S.6    Awjr, C.7
  • 59
    • 33745609228 scopus 로고    scopus 로고
    • Mitochondrial metabolic states regulate nitric oxide and hydrogen peroxide diffusion to the cytosol
    • Boveris A, Valdez LB, Zaobornyj T, Bustamante J. Mitochondrial metabolic states regulate nitric oxide and hydrogen peroxide diffusion to the cytosol. Biochim Biophys Acta 2006; 1757: 535-542.
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 535-542
    • Boveris, A.1    Valdez, L.B.2    Zaobornyj, T.3    Bustamante, J.4
  • 60
    • 84868211606 scopus 로고    scopus 로고
    • A mitochondrial permeability transition pore inhibitor improves renal outcomes after revascularization in experimental atherosclerotic renal artery stenosis
    • Eirin A, Li Z, Zhang X, Krier JD, Woollard JR, Zhu XY, Tang H, Herrmann SM, Lerman A, Textor SC, Lerman LO. A mitochondrial permeability transition pore inhibitor improves renal outcomes after revascularization in experimental atherosclerotic renal artery stenosis. Hypertension 2012; 60: 1242-1249.
    • (2012) Hypertension , vol.60 , pp. 1242-1249
    • Eirin, A.1    Li, Z.2    Zhang, X.3    Krier, J.D.4    Woollard, J.R.5    Zhu, X.Y.6    Tang, H.7    Herrmann, S.M.8    Lerman, A.9    Textor, S.C.10    Lerman, L.O.11
  • 61
    • 84877743633 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor delta agonist, hpp593, prevents renal necrosis under chronic ischemia
    • Fedorova LV, Sodhi K, Gatto-Weis C, Puri N, Hinds TD Jr, Shapiro JI, Malhotra D. Peroxisome proliferator-Activated receptor delta agonist, HPP593, prevents renal necrosis under chronic ischemia. PLoS ONE 2013; 8: e64436.
    • (2013) PLoS ONE , vol.8 , pp. e64436
    • Fedorova, L.V.1    Sodhi, K.2    Gatto-Weis, C.3    Puri, N.4    Hinds, T.D.5    Shapiro, J.I.6    Malhotra, D.7
  • 62
    • 77956267257 scopus 로고    scopus 로고
    • Losartan improved respiratory function and coenzyme q content in brain mitochondria of young spontaneously hypertensive rats
    • Sumbalova Z, Kucharska J, Kristek F. Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats. Cell Mol Neurobiol 2010; 30: 751-758.
    • (2010) Cell Mol Neurobiol , vol.30 , pp. 751-758
    • Sumbalova, Z.1    Kucharska, J.2    Kristek, F.3
  • 63
    • 16544372170 scopus 로고    scopus 로고
    • Decreased atp-synthesis ability of brain mitochondria in spontaneously hypertensive rats
    • Doroshchuk AD, Postnov A, Afanaseva GV, Budnikov E, PostnovIu V. [Decreased ATP-synthesis ability of brain mitochondria in spontaneously hypertensive rats]. Kardiologiia 2004; 44: 64-65.
    • (2004) Kardiologiia , vol.44 , pp. 64-65
    • Doroshchuk, A.D.1    Postnov, A.2    Afanaseva, G.V.3    Budnikov, E.4    Postnoviu, V.5
  • 65
    • 0036919755 scopus 로고    scopus 로고
    • Long-Term angiotensin ii inhibition increases mitochondrial nitric oxide synthase and not antioxidant enzyme activities in rat heart
    • Costa LE, La-Padula P, Lores-Arnaiz S, DAmico G, Boveris A, Kurnjek ML, Basso N. Long-Term angiotensin ii inhibition increases mitochondrial nitric oxide synthase and not antioxidant enzyme activities in rat heart. J Hypertens 2002; 20: 2487-2494.
    • (2002) J Hypertens , vol.20 , pp. 2487-2494
    • Costa, L.E.1    La-Padula, P.2    Lores-Arnaiz, S.3    Boveris, A.4    Kurnjek, M.L.5    Basso, N.6
  • 67
    • 67650173949 scopus 로고    scopus 로고
    • Cardiac mitochondrial function and tissue remodelling are improved by a non-Antihypertensive dose of enalapril in spontaneously hypertensive rats
    • Piotrkowski B, Koch OR, De Cavanagh EM, Fraga CG. Cardiac mitochondrial function and tissue remodelling are improved by a non-Antihypertensive dose of enalapril in spontaneously hypertensive rats. Free Radic Res 2009; 43: 390-399.
    • (2009) Free Radic Res , vol.43 , pp. 390-399
    • Piotrkowski, B.1    Koch, O.R.2    De Cavanagh, E.M.3    Fraga, C.G.4
  • 69
    • 34147116081 scopus 로고    scopus 로고
    • Mitochondrial function and nitric oxide metabolism are modified by enalapril treatment in rat kidney
    • Piotrkowski B, Fraga CG, de Cavanagh EM. Mitochondrial function and nitric oxide metabolism are modified by enalapril treatment in rat kidney.Am J Physiol Regul Integr Comp Physiol 2007; 292: R1494-R1501.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , pp. R1494-R1501
    • Piotrkowski, B.1    Fraga, C.G.2    De Cavanagh, E.M.3
  • 71
    • 41949104144 scopus 로고    scopus 로고
    • Molecular mechanisms of angiotensin ii-mediated mitochondrial dysfunction: Linking mitochondrial oxidative damage and vascular endothelial dysfunction
    • Doughan AK, Harrison DG, Dikalov SI. Molecular mechanisms of angiotensin ii-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ Res 2008; 102: 488-496.
    • (2008) Circ Res , vol.102 , pp. 488-496
    • Doughan, A.K.1    Harrison, D.G.2    Dikalov, S.I.3
  • 72
    • 0028365310 scopus 로고
    • Angiotensin ii stimulates nadh and nadph oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin ii stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74: 1141-1148.
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 73
    • 0028946337 scopus 로고
    • Superoxide dismutase and glutathione peroxidase activities are increased by enalapril and captopril in mouse liver
    • de Cavanagh EM, Inserra F, Ferder L, Romano L, Ercole L, Fraga CG. Superoxide dismutase and glutathione peroxidase activities are increased by enalapril and captopril in mouse liver. FEBS Lett 1995; 361: 22-24.
    • (1995) FEBS Lett , vol.361 , pp. 22-24
    • De Cavanagh, E.M.1    Inserra, F.2    Ferder, L.3    Romano, L.4    Ercole, L.5    Fraga, C.G.6
  • 76
    • 84894067221 scopus 로고    scopus 로고
    • Combined therapeutic benefit of mitochondria-Targeted antioxidant, mitoq10, and angiotensin receptor blocker, losartan, on cardiovascular function
    • McLachlan J, Beattie E, Murphy MP, Koh-Tan CH, Olson E, Beattie W, Dominiczak AF, Nicklin SA, Graham D. Combined therapeutic benefit of mitochondria-Targeted antioxidant, Mitoq10, and angiotensin receptor blocker, losartan, on cardiovascular function. J Hypertens 2014; 32: 555-564.
    • (2014) J Hypertens , vol.32 , pp. 555-564
    • McLachlan, J.1    Beattie, E.2    Murphy, M.P.3    Koh-Tan, C.H.4    Olson, E.5    Beattie, W.6    Dominiczak, A.F.7    Nicklin, S.A.8    Graham, D.9
  • 77
    • 12344334666 scopus 로고    scopus 로고
    • Cyclosporine protects against ischemia/reperfusion injury in rat kidneys
    • Singh D, Chander V, Chopra K. Cyclosporine protects against ischemia/reperfusion injury in rat kidneys. Toxicology 2005; 207: 339-347.
    • (2005) Toxicology , vol.207 , pp. 339-347
    • Singh, D.1    Chander, V.2    Chopra, K.3
  • 78
    • 0027325502 scopus 로고
    • Acute cyclosporine-induced renal vasoconstriction is mediated by endothelin-1
    • 480-487; discussion
    • Bloom IT, Bentley FR, Garrison RN. Acute cyclosporine-induced renal vasoconstriction is mediated by endothelin-1. Surgery 1993; 114: 480-487; discussion 487-488.
    • (1993) Surgery , vol.114 , pp. 487-488
    • Bloom, I.T.1    Bentley, F.R.2    Garrison, R.N.3
  • 79
    • 0032949880 scopus 로고    scopus 로고
    • Cyclosporin-induced hypertension: Incidence, pathogenesis and management
    • Taler SJ, Textor SC, Canzanello VJ, Schwartz L. Cyclosporin-induced hypertension: incidence, pathogenesis and management. Drug Saf 1999; 20: 437-449.
    • (1999) Drug Saf , vol.20 , pp. 437-449
    • Taler, S.J.1    Textor, S.C.2    Canzanello, V.J.3    Schwartz, L.4
  • 80
    • 84897457350 scopus 로고    scopus 로고
    • First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics
    • Szeto HH. First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. Br J Pharmacol 2014; 171: 2029-2050.
    • (2014) Br J Pharmacol , vol.171 , pp. 2029-2050
    • Szeto, H.H.1
  • 83
    • 77955283395 scopus 로고    scopus 로고
    • Animal and human studies with the mitochondria-Targeted antioxidant mitoq
    • Smith RAJ, Murphy MP. Animal and human studies with the mitochondria-Targeted antioxidant mitoq. Ann N Y Acad Sci 2010; 1201: 96-103.
    • (2010) Ann N y Acad Sci , vol.1201 , pp. 96-103
    • Smith, R.A.J.1    Murphy, M.P.2
  • 85
    • 84875422028 scopus 로고    scopus 로고
    • Rationale and design of the embrace stemi study: A phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for st-segment elevation myocardial infarction
    • e507
    • Chakrabarti AK, Feeney K, Abueg C, Brown DA, Czyz E, Tendera M, Janosi A, Giugliano RP, Kloner RA, Weaver WD, Bode C, Godlewski J, Merkely B, Gibson CM. Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for st-segment elevation myocardial infarction. Am Heart J 2013; 165: 509-514.e507.
    • (2013) Am Heart J , vol.165 , pp. 509-514
    • Chakrabarti, A.K.1    Feeney, K.2    Abueg, C.3    Brown, D.A.4    Czyz, E.5    Tendera, M.6    Janosi, A.7    Giugliano, R.P.8    Kloner, R.A.9    Weaver, W.D.10    Bode, C.11    Godlewski, J.12    Merkely, B.13    Gibson, C.M.14


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.