Mitochondrial dysfunction in the hypertensive rat brain: Respiratory complexes exhibit assembly defects in hypertension

Hypertension

Volumn 51, Issue 2, 2008, Pages 412-419

  Lopez Campistrous, Ana ^a   Hao, Li ^a   Xiang, Wang ^a   Ton, Dong ^a   Semchuk, Paul ^a   Sander, Joerg ^a   Ellison, Michael J ^a   Fernandez Patron, Carlos ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Brain; Hypertension; Mitochondria; Oxidative stress; Proteomics

Indexed keywords

CYTOCHROME C OXIDASE; DOXYCYCLINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RESPIRATORY COMPLEX V; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BRAIN MITOCHONDRION; BRAIN STEM; CELL ENERGY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; ENZYME SYNTHESIS; HOMEOSTASIS; HYPERTENSION; MITOCHONDRIAL RESPIRATION; MITOCHONDRION DYSFUNCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; RAT; RATING SCALE; SPONTANEOUSLY HYPERTENSIVE RAT; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL ELECTROPHORESIS; ULTRACENTRIFUGATION; WESTERN BLOTTING; WISTAR KYOTO RAT;

ANIMALS; BRAIN; CARDIOVASCULAR SYSTEM; DOXYCYCLINE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INHIBITORS; HOMEOSTASIS; HYPERTENSION; METALLOENDOPEPTIDASES; MITOCHONDRIAL DISEASES; MULTIENZYME COMPLEXES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; TANDEM MASS SPECTROMETRY;

EID: 38549101488     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.102285     Document Type: Article

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