Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts

American Journal of Physiology - Cell Physiology

Volumn 297, Issue 3, 2009, Pages

  Hickey, Anthony J R ^a   Chai, Chau C ^a   Choong, Soon Y ^a   De Freitas Costa, Silvana ^a   Skea, Gretchen L ^a   Phillips, Anthony R J ^a   Cooper, Garth J S ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Adenylate control; Complex I dysfunction; Hypertensive heart; Oxidative stress; Respiration; Saponin permeabilized fibers

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; MYOSIN ADENOSINE TRIPHOSPHATASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE PRESSURE; HEART MITOCHONDRION; HEART MUSCLE COMPLIANCE; HEART PRELOAD; HYDROLYSIS; LIPID PEROXIDATION; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL VOLUME; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIROMETRY; SPONTANEOUSLY HYPERTENSIVE RAT; TRANSMISSION ELECTRON MICROSCOPY; WISTAR KYOTO RAT;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; HEART; LIPID PEROXIDATION; MITOCHONDRIA, HEART; MYOCARDIUM; OXYGEN CONSUMPTION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SUPEROXIDES;

RATTUS;

EID: 70349230846     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00111.2009     Document Type: Article

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