Protein kinase C and Ca2+-calmodulin-dependent protein kinase II mediate the enlarged reverse INCX induced by ouabain-increased late sodium current in rabbit ventricular myocytes

Experimental Physiology

Volumn 100, Issue 4, 2015, Pages 399-409

  Wu, Ying ^a   Wang, Leilei ^a   Ma, Jihua ^a   Song, Yejia ^b   Zhang, Peihua ^a   Luo, Antao ^a   Fu, Chen ^a   Cao, Zhenzhen ^a   Wang, Xiaojing ^a   Shryock, John C ^c   Belardinelli, Luiz ^c  

^a WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c Gilead Sciences ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISINDOLYLMALEIMIDE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; OUABAIN; PROTEIN KINASE C; RANOLAZINE; CALCIUM; CARDIOTONIC AGENT; ENZYME INHIBITOR; SODIUM;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; FEMALE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; INOTROPISM; MALE; NONHUMAN; PROTEIN FUNCTION; RABBIT; SARCOMERE; SODIUM CALCIUM EXCHANGE; SODIUM CURRENT; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CHANNEL GATING; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; HEART CONTRACTION; HEART VENTRICLE; MEMBRANE POTENTIAL; METABOLISM; PHYSIOLOGY;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CARDIOTONIC AGENTS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; HEART VENTRICLES; ION CHANNEL GATING; MEMBRANE POTENTIALS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; OUABAIN; PROTEIN KINASE C; RABBITS; SODIUM;

EID: 84926132415     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2014.083972     Document Type: Article

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