Different roles of the cardiac Na+/Ca+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 3, 2013, Pages

  Bai, Yan ^a,c   Morgan, Eric E ^a   Giovannucci, David R ^a   Pierre, Sandrine V ^a   Philipson, Kenneth D ^b   Askari, Amir ^a   Liu, Lijun ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Calcium; Cardiac hypertrophy; PI3K; Positive inotropy

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; ENDOTHELIN 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OUABAIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE 1A; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ENZYME ACTIVATION; HEART HYPERTROPHY; HEART MUSCLE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SODIUM CALCIUM EXCHANGE; UPREGULATION; WILD TYPE;

ANIMALS; CALCIUM; CARDIOMEGALY; CARDIOTONIC AGENTS; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MALE; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; ONCOGENE PROTEIN V-AKT; OUABAIN; PHOSPHATIDYLINOSITOL 3-KINASES; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SODIUM-CALCIUM EXCHANGER; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84873320165     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00462.2012     Document Type: Article

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