Functional effects of protein kinase C activation on the human cardiac Na+ channel

Circulation Research

Volumn 80, Issue 3, 1997, Pages 370-376

  Murray, Katherine T ^a   Hu, Ningning ^a   Daw, J Richard ^a   Shin, Hyeon Gyu ^a   Watson, Marshall T ^a   Mashburn, Amy B ^a   George Jr , Alfred L ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

heart; phosphorylation; protein kinase C; sodium channels; xenopus oocyte

Indexed keywords

ALPHA 1B ADRENERGIC RECEPTOR; CHELERYTHRINE; GLYCEROL 2 ACETATE 1 OLEATE; METHOXAMINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; SODIUM CHANNEL;

ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; XENOPUS LAEVIS;

EID: 0031051126     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.80.3.370     Document Type: Article

References (33)

1. El-Sherif N, Reentrant mechanisms in ventricular arrhythmias. In; Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. Philadelphia, Pa: WB Saunders; 1995:576-582.
2. Poole JE, Bardy GH. Sudden cardiac death. In: Zipes DP. Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. Philadelphia, Pa: WB Saunders; 1995:812-832.
3. Wang Q, Shen J, Splawski I, Atkinson D, Li Z, Robinson JL, Moss AJ, Towbin JA, Keating MT. SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Cell. 1995;80: 805-811.
4. Wang Q, Shen J, Li Z, Timothy K, Vincent GM, Priori SG, Schwanz PJ. Keating MT. Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia. Hum Mol Genet, 1995;4:1603-1607.
5. Podrid PJ. Fuchs T, Candinas R. Role of the sympathetic nervous system in the genesis of ventricular arrhythmia. Circulation. 1990; 82(suppll):I 103-l-113.
6. Corr PB. Heathers GP, Yamada KA. Mechanisms contributing to the arrhythmogenic influences of aiphai-adrenergic stimulation in the ischemic heart. Am J Meet. 1987;87{suppl a):I9S-25S.
7. Webster MW. Fitzpatrick MA, Nicholls MG, Ikram H, Wells JE. Effect of enalapril on ventricular arrhythmias in congestive heart failure. Am J Cardiol. 1985;56:566-569.
8. + channels by antiarrhythmic drugs, neurotransmitters and hormones, Trends Phannacal Sci. 1992;13;352-358.
9. Ono K, Fozzard HA, Hanck DA, Mechanism of cAMP-dependent modulation of cardiac sodium channel current kinetics. Circ Res. 1993;72:807-815.
10. Gintant GA, Liu D-W. β-Adrenergic modulation of fast inward sodium current in canine myocardium: syncytial preparations versus isolated myocytes. Ore Res. 1992;70:844-850.
11. + channels in neonatal rat. Circ Res, 1989; 65:1804-1809.
12. + channels, J Membr Biol. 1992; 130:183-190.
13. Nilius B, Tytgat J, Albitz R, Modulation of cardiac Na channels by angiotensin II. Biochim Biophys Acta, 1989;1014:259-262.
14. Gellens ME, George AL, Chen L, Chahine M, Horn R, Barchi RL, Kallen RG. Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel. Proc Natl Acad Sci U S A. 1992;89:554-558.
15. Numann R, Catterall WA, Scheuer T. Functional modulation of brain sodium channels by protein kinase C phosphorylation. Science. 1991; 254:115-118.
16. + channel required for modulation by protein kinase C. Science. 1991;254:866-868.
17. + channel by protein kinase C. Cric Res. 1994;75:999-1005.
18. 1-adrenergic receptor. Proc Natl Acad Sci U S A. 1988; 85:7159-7163.
19. Hoger JH. Walter AE, Vance D, Yu L, Lester HA, Davidson N. Modulation of a cloned mouse brain potassium channel, Neuron. 1991;6:227-236.
20. Kass RS, Bennett PB. Microeleetrode voltage clamp; the cardiac Purkinje fiber. In: Smith TG, Lecar H, Redman S, Gage P, eds. Voltage and Patch Clamping with Microelectrodes. Bethesda, Md: Waverly Press; 1985:178-191.
21. Po S, Snyders DJ, Baker R, Tamkun MM, Bennett PB. Functional expression of an inactivating potassium channel cloned from human heart. Circ Res, 1992;71:732-736.
22. Murray KT, Anno T, Bennett PB, Hondegbem LM. Voltage clamp of the cardiac sodium current at 37°C in physiologic solutions. Biophys J. 1990;57:607-613.
23. Higuchi R. Using PCR to engineer DNA, In: Erlich HA, ed. PCR Technology. New York, NY: Stockston; 1989:61-70.
24. Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR. Site-directed mutagenesis by overlap extension using the polymerase chain reaction, Gene. 1989;77:51-59.
25. +-ATPase in oocytes of Xenopus laevis. J Membr Biol. 1990;118:131-142.
26. Herbert JM, Augereau JM, Gleye J, Maffrand JP. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun. 1990;172:993-999.
27. + channel by protein kinase C. Proc Natl Acad Sci U S A. 1995;92: 12003-12007.
28. + channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C. Proc Natl Acad Sci U S A. 1994;91:3289-3293.
29. Weigl L, Frohnwieser B, Spreitzer B, Kalten R, Schreibmayer W. Modulation of cardiac sodium channel a-subunits by protein kinase C. Biophys J. 1994;66:A202. Abstract.
30. Ks, potassium channel. Nature. 1996;384:80-83.
31. Ks cardiac potassium current, Nature. 1996;384:78-80.
32. + channel in mouse heart, EMBO J. 1991;10:2805-2811.
33. Ks, and mediates species-specific responses to protein kinase C. Proc Natl Acad Sci U S A. 1993;90:11528-11532.