Ranolazine attenuates the enhanced reverse Na+-Ca2+ exchange current via inhibiting hypoxia-increased late sodium current in ventricular myocytes

Journal of Pharmacological Sciences

Volumn 124, Issue 3, 2014, Pages 365-373

  Wang, Xiao Jing ^a   Wang, Lei Lei ^a   Fu, Chen ^a   Zhang, Pei Hua ^a   Wu, Ying ^a   Ma, Ji Hua ^a  

^a WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Hypoxia; Late sodium current; Patch clamp technique; Ranolazine; Sodium calcium exchanger

Indexed keywords

CALCIUM; CELL PROTEIN; INCREASED LATE SODIUM CURRENT; RANOLAZINE; SODIUM; TETRODOTOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL HYPOXIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DOWN REGULATION; DRUG EFFECT; EARLY AFTER DEPOLARIZATION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; NONHUMAN; SODIUM CALCIUM EXCHANGE; WHOLE CELL PATCH CLAMP;

ACETANILIDES; ACTION POTENTIALS; ANIMALS; ANOXIA; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HEART VENTRICLES; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PIPERAZINES; RABBITS; SODIUM; SODIUM-CALCIUM EXCHANGER; TETRODOTOXIN;

EID: 84897411260     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.13202FP     Document Type: Article

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