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Volumn 15, Issue 10, 2014, Pages 931-942

Chemoresistance in high-grade gliomas: Relevance of adenosine signalling in stem-like cells of glioblastoma multiforme

Author keywords

Adenosine; Adenosine A3 receptor; Glioblastoma multiforme; Glioblastoma stem like cells; Multiple drugs resistance associated protein 1 (Mrp1) transporter

Indexed keywords

5' NUCLEOTIDASE; ABC TRANSPORTER; ACID PHOSPHATASE PROSTATE ISOENZYME; ADENOSINE; ADENOSINE A3 RECEPTOR; ADENOSINE PHOSPHATE; BEVACIZUMAB; GLUTATHIONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LUNG RESISTANCE PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MULTIDRUG RESISTANCE PROTEIN; RAL PROTEIN; REACTIVE OXYGEN METABOLITE; TEMOZOLOMIDE; VASCULOTROPIN; ANTINEOPLASTIC AGENT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1;

EID: 84925946155     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (174)
  • 1
    • 79960555749 scopus 로고    scopus 로고
    • Study of resistance to chemotherapy mediated by ABC transporters in biopsies of glioblastoma multiforme
    • Quezada C, Peigñan L, Segura R, et al. Study of resistance to chemotherapy mediated by ABC transporters in biopsies of glioblastoma multiforme. Rev Med Chil 2011; 39(4): 415-24.
    • (2011) Rev Med Chil , vol.39 , Issue.4 , pp. 415-424
    • Quezada, C.1    Peigñan, L.2    Segura, R.3
  • 2
    • 77349117235 scopus 로고    scopus 로고
    • Survival comparison between glioblastoma multiforme and other incurable cancers
    • Tran B, Rosenthal MA. Survival comparison between glioblastoma multiforme and other incurable cancers. J Clin Neurosci 2010; 17(4): 417-21.
    • (2010) J Clin Neurosci , vol.17 , Issue.4 , pp. 417-421
    • Tran, B.1    Rosenthal, M.A.2
  • 3
    • 79961206982 scopus 로고    scopus 로고
    • Combined use of anticancer drugs and an inhibitor of multiple drug resistance-associated protein-1 increases sensitivity and decreases survival of glioblastoma multiforme cells in vitro
    • Peigñan L, Garrido W, Segura R, et al. Combined use of anticancer drugs and an inhibitor of multiple drug resistance-associated protein-1 increases sensitivity and decreases survival of glioblastoma multiforme cells in vitro. Neurochem Res 2011; 36(8): 1397-406.
    • (2011) Neurochem Res , vol.36 , Issue.8 , pp. 1397-1406
    • Peigñan, L.1    Garrido, W.2    Segura, R.3
  • 4
    • 77955604252 scopus 로고    scopus 로고
    • Novel medical therapeutics in glioblastomas, including targeted molecular therapies, current and future clinical trials
    • Quant EC, Wen PY. Novel medical therapeutics in glioblastomas, including targeted molecular therapies, current and future clinical trials. Neuroimaging Clin N Am 2010; 20(3): 425-48.
    • (2010) Neuroimaging Clin N Am , vol.20 , Issue.3 , pp. 425-448
    • Quant, E.C.1    Wen, P.Y.2
  • 5
    • 77749338221 scopus 로고    scopus 로고
    • Recent advances in therapy for glioblastoma
    • Clarke J, Butowski N, Chang S. Recent advances in therapy for glioblastoma. Arch Neurol 2010; 67(3): 279-83.
    • (2010) Arch Neurol , vol.67 , Issue.3 , pp. 279-283
    • Clarke, J.1    Butowski, N.2    Chang, S.3
  • 6
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003; 63(18): 5821-8.
    • (2003) Cancer Res , vol.63 , Issue.18 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3
  • 8
    • 78951487499 scopus 로고    scopus 로고
    • Glioma-initiating cells and molecular pathology: Implications for therapy
    • Natsume A, Kinjo S, Yuki K, et al. Glioma-initiating cells and molecular pathology: implications for therapy. Brain Tumor Pathol 2011; 28(1): 1-12.
    • (2011) Brain Tumor Pathol , vol.28 , Issue.1 , pp. 1-12
    • Natsume, A.1    Kinjo, S.2    Yuki, K.3
  • 9
    • 79953813644 scopus 로고    scopus 로고
    • Glioblastoma stem cells
    • Tabatabai G, Weller M. Glioblastoma stem cells. Cell Tissue Res 2011; 343(3): 459-65.
    • (2011) Cell Tissue Res , vol.343 , Issue.3 , pp. 459-465
    • Tabatabai, G.1    Weller, M.2
  • 11
    • 79952993517 scopus 로고    scopus 로고
    • Multidrug efflux pumps and cancer stem cells: Insights into multidrug resistance and therapeutic development
    • Moitra K, Lou H, Dean M. Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development. Clin Pharmacol Ther 2011; 89(4): 491-502.
    • (2011) Clin Pharmacol Ther , vol.89 , Issue.4 , pp. 491-502
    • Moitra, K.1    Lou, H.2    Dean, M.3
  • 12
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006; 444(7120): 756-60.
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3
  • 13
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
    • Liu G, Yuan X, Zeng Z, et al. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer 2006; 5: 67.
    • (2006) Mol Cancer , vol.5 , pp. 67
    • Liu, G.1    Yuan, X.2    Zeng, Z.3
  • 14
    • 34848899578 scopus 로고    scopus 로고
    • Chemotherapy and cancer stem cells
    • Rich JN, Bao S. Chemotherapy and cancer stem cells. Cell Stem Cell 2007; 1(4): 353-55.
    • (2007) Cell Stem Cell , vol.1 , Issue.4 , pp. 353-355
    • Rich, J.N.1    Bao, S.2
  • 15
    • 70350317445 scopus 로고    scopus 로고
    • Chemotherapeutic treatment of gliomas increases the amount of cancer stem-like cells
    • Bleau AM, Holland EC. Chemotherapeutic treatment of gliomas increases the amount of cancer stem-like cells. Med Sci (Paris) 2009; 25(10): 775-7.
    • (2009) Med Sci (Paris) , vol.25 , Issue.10 , pp. 775-777
    • Bleau, A.M.1    Holland, E.C.2
  • 16
    • 33745198882 scopus 로고    scopus 로고
    • Chemotherapy resistance of glioblastoma stem cells
    • Eramo A, Ricci-Vitiani L, Zeuner A, et al. Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ 2006; 13(7): 1238-41.
    • (2006) Cell Death Differ , vol.13 , Issue.7 , pp. 1238-1241
    • Eramo, A.1    Ricci-Vitiani, L.2    Zeuner, A.3
  • 17
    • 33750541962 scopus 로고    scopus 로고
    • Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype
    • Salmaggi A, Boiardi A, Gelati M, et al. Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype. Glia 2006; 54(8): 850-60.
    • (2006) Glia , vol.54 , Issue.8 , pp. 850-860
    • Salmaggi, A.1    Boiardi, A.2    Gelati, M.3
  • 18
    • 53449085011 scopus 로고    scopus 로고
    • Glioblastoma and stem cells
    • Altaner C. Glioblastoma and stem cells. Neoplasma 2008; 55(5): 369-74.
    • (2008) Neoplasma , vol.55 , Issue.5 , pp. 369-374
    • Altaner, C.1
  • 19
    • 77953125390 scopus 로고    scopus 로고
    • Influence of Etoposide on antiapoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells
    • Jin F, Zhao L, Guo YJ, et al. Influence of Etoposide on antiapoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells. Brain Res 2010; 1336: 103-11.
    • (2010) Brain Res , vol.1336 , pp. 103-111
    • Jin, F.1    Zhao, L.2    Guo, Y.J.3
  • 20
    • 51049101689 scopus 로고    scopus 로고
    • Targeting cancer stem cells through L1CAM suppresses glioma growth
    • Bao S, Wu Q, Li Z, et al. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res 2008; 68(15): 6043-8.
    • (2008) Cancer Res , vol.68 , Issue.15 , pp. 6043-6048
    • Bao, S.1    Wu, Q.2    Li, Z.3
  • 21
    • 79953189403 scopus 로고    scopus 로고
    • Cancer stem cells in glioblastoma-molecular signaling and therapeutic targeting
    • Huang Z, Cheng L, Guryanova OA, et al. Cancer stem cells in glioblastoma-molecular signaling and therapeutic targeting. Protein Cell 2010; 1(7): 638-55.
    • (2010) Protein Cell , vol.1 , Issue.7 , pp. 638-655
    • Huang, Z.1    Cheng, L.2    Guryanova, O.A.3
  • 22
    • 70349572622 scopus 로고    scopus 로고
    • ABC transporters as potential targets for modulation of drug resistance
    • Gatti L, Beretta GL, Cossa G, et al. ABC transporters as potential targets for modulation of drug resistance. Mini Rev Med Chem 2009; 9(9): 1102-12.
    • (2009) Mini Rev Med Chem , vol.9 , Issue.9 , pp. 1102-1112
    • Gatti, L.1    Beretta, G.L.2    Cossa, G.3
  • 23
    • 79960566297 scopus 로고    scopus 로고
    • FK506 confers chemosensitivity to anticancer drugs in glioblastoma multiforme cells by decreasing the expression of the multiple resistanceassociated protein-1
    • Garrido W, Munoz M, San Martin R, et al. FK506 confers chemosensitivity to anticancer drugs in glioblastoma multiforme cells by decreasing the expression of the multiple resistanceassociated protein-1. Biochem Biophys Res Commun 2011; 411(1): 62-8.
    • (2011) Biochem Biophys Res Commun , vol.411 , Issue.1 , pp. 62-68
    • Garrido, W.1    Munoz, M.2    San Martin, R.3
  • 24
    • 34548602528 scopus 로고    scopus 로고
    • Chemoresistance of CD133(+) tumor stem cells from human brain glioma
    • Bi CL, Fang JS, Chen FH, et al. Chemoresistance of CD133(+) tumor stem cells from human brain glioma. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007; 32(4): 568-73.
    • (2007) Zhong Nan Da Xue Xue Bao Yi Xue Ban , vol.32 , Issue.4 , pp. 568-573
    • Bi, C.L.1    Fang, J.S.2    Chen, F.H.3
  • 25
    • 46549084099 scopus 로고    scopus 로고
    • Comparison between cells and cancer stem-like cells isolated from glioblastoma and astrocytoma on expression of anti-apoptotic and multidrug resistance-associated protein genes
    • Jin F, Zhao L, Zhao HY, et al. Comparison between cells and cancer stem-like cells isolated from glioblastoma and astrocytoma on expression of anti-apoptotic and multidrug resistance-associated protein genes. Neuroscience 2008; 154(2): 541-50.
    • (2008) Neuroscience , vol.154 , Issue.2 , pp. 541-550
    • Jin, F.1    Zhao, L.2    Zhao, H.Y.3
  • 26
    • 70349296853 scopus 로고    scopus 로고
    • The ABCG2 resistance network of glioblastoma
    • Bleau AM, Huse JT, Holland EC. The ABCG2 resistance network of glioblastoma. Cell Cycle 2009; 8(18): 2936-44.
    • (2009) Cell Cycle , vol.8 , Issue.18 , pp. 2936-2944
    • Bleau, A.M.1    Huse, J.T.2    Holland, E.C.3
  • 27
    • 79959928027 scopus 로고    scopus 로고
    • Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroids
    • Kolenda J, Jensen SS, Aaberg-Jessen C, et al. Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroids. J Neurooncol 2011; 103(1): 43-58.
    • (2011) J Neurooncol , vol.103 , Issue.1 , pp. 43-58
    • Kolenda, J.1    Jensen, S.S.2    Aaberg-Jessen, C.3
  • 28
    • 0036636724 scopus 로고    scopus 로고
    • Brain-tumour drug resistance: The bare essentials
    • Bredel M, Zentner J. Brain-tumour drug resistance: the bare essentials. Lancet Oncol 2002; 3(7): 397-406.
    • (2002) Lancet Oncol , vol.3 , Issue.7 , pp. 397-406
    • Bredel, M.1    Zentner, J.2
  • 29
    • 78049515473 scopus 로고    scopus 로고
    • Temozolomide versus procarbazine, lomustine, and vincristine in recurrent high-grade glioma
    • Brada M, Stenning S, Gabe R, et al. Temozolomide versus procarbazine, lomustine, and vincristine in recurrent high-grade glioma. J Clin Oncol 2010; 28(30): 4601-8.
    • (2010) J Clin Oncol , vol.28 , Issue.30 , pp. 4601-4608
    • Brada, M.1    Stenning, S.2    Gabe, R.3
  • 30
    • 32944481699 scopus 로고    scopus 로고
    • PCV chemotherapy for recurrent glioblastoma
    • Schmidt F, Fischer J, Herrlinger U, et al. PCV chemotherapy for recurrent glioblastoma. Neurology 2006; 66(4): 587-9.
    • (2006) Neurology , vol.66 , Issue.4 , pp. 587-589
    • Schmidt, F.1    Fischer, J.2    Herrlinger, U.3
  • 31
    • 33747169623 scopus 로고    scopus 로고
    • Standard treatment and experimental targeted drug therapy for recurrent glioblastoma multiforme
    • Chang SM, Butowski NA, Sneed PK, et al. Standard treatment and experimental targeted drug therapy for recurrent glioblastoma multiforme. Neurosurg Focus 2006; 20(4): E4.
    • (2006) Neurosurg Focus , vol.20 , Issue.4
    • Chang, S.M.1    Butowski, N.A.2    Sneed, P.K.3
  • 32
    • 33646568511 scopus 로고    scopus 로고
    • Mechanisms and strategies to overcome multiple drug resistance in cancer
    • Ozben T. Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett 2006; 580(12): 2903-9.
    • (2006) FEBS Lett , vol.580 , Issue.12 , pp. 2903-2909
    • Ozben, T.1
  • 33
    • 84870424506 scopus 로고    scopus 로고
    • 5'-ectonucleotidase mediates multiple-drug resistance in glioblastoma multiforme cells
    • Quezada C, Garrido W, Oyarzun C, et al. 5'-ectonucleotidase mediates multiple-drug resistance in glioblastoma multiforme cells. J Cell Physiol 2013; 228(3): 602-8.
    • (2013) J Cell Physiol , vol.228 , Issue.3 , pp. 602-608
    • Quezada, C.1    Garrido, W.2    Oyarzun, C.3
  • 34
    • 84925943449 scopus 로고    scopus 로고
    • Study of the role of extracellular adenosine on chemoresistance in glioblastoma stemlike cells
    • Quezada C, Garrido W, Rocha JD, et al. Study of the role of extracellular adenosine on chemoresistance in glioblastoma stemlike cells. FEBS J 2013; 280: 201SI.
    • (2013) FEBS J , vol.280 , pp. 201
    • Quezada, C.1    Garrido, W.2    Rocha, J.D.3
  • 35
    • 21044459993 scopus 로고    scopus 로고
    • Optimal role of temozolomide in the treatment of malignant gliomas
    • Stupp R, van den Bent MJ, Hegi ME. Optimal role of temozolomide in the treatment of malignant gliomas. Curr Neurol Neurosci Rep 2005; 5(3): 198-206.
    • (2005) Curr Neurol Neurosci Rep , vol.5 , Issue.3 , pp. 198-206
    • Stupp, R.1    van den Bent, M.J.2    Hegi, M.E.3
  • 36
    • 77955378377 scopus 로고    scopus 로고
    • Mesenchymal migration as a therapeutic target in glioblastoma
    • Zhong J, Paul A, Kellie SJ, et al. Mesenchymal migration as a therapeutic target in glioblastoma. J Oncol 2010; 2010: 430142.
    • (2010) J Oncol , vol.2010
    • Zhong, J.1    Paul, A.2    Kellie, S.J.3
  • 37
    • 33847630104 scopus 로고    scopus 로고
    • Tendencia de la mortalidad por tumores cerebrales malignos en Chile. Análisis de tasas
    • Díaz V, Yañez A, Ponce C, et al. Tendencia de la mortalidad por tumores cerebrales malignos en Chile. Análisis de tasas. Rev Chil Neuro-Psiquiat 2006; 44: 263-70.
    • (2006) Rev Chil Neuro-Psiquiat , vol.44 , pp. 263-270
    • Díaz, V.1    Yañez, A.2    Ponce, C.3
  • 38
    • 57449117296 scopus 로고    scopus 로고
    • Pediatric glioblastoma cell line shows different patterns of expression of transmembrane ABC transporters after in vitro exposure to vinblastine
    • Valera ET, de Freitas Cortez MA, de Paula Queiroz RG, et al. Pediatric glioblastoma cell line shows different patterns of expression of transmembrane ABC transporters after in vitro exposure to vinblastine. Childs Nerv Syst 2009; 25(1): 39-45.
    • (2009) Childs Nerv Syst , vol.25 , Issue.1 , pp. 39-45
    • Valera, E.T.1    de Freitas Cortez, M.A.2    de Paula Queiroz, R.G.3
  • 39
  • 40
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010
    • Jemal A, Siegel R, Xu J, et al. Cancer statistics, 2010. CA Cancer J Clin 2010; 60(5): 277-300.
    • (2010) CA Cancer J Clin , vol.60 , Issue.5 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3
  • 42
    • 0036316548 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown in septic encephalopathy and brain tumours
    • Davies DC. Blood-brain barrier breakdown in septic encephalopathy and brain tumours. J Anat 2002; 200(6): 639-46.
    • (2002) J Anat , vol.200 , Issue.6 , pp. 639-646
    • Davies, D.C.1
  • 43
    • 33646428102 scopus 로고    scopus 로고
    • Blood-brain barrier interfaces and brain tumors
    • Lee SW, Kim WJ, Park JA, et al. Blood-brain barrier interfaces and brain tumors. Arch Pharm Res 2006; 29(4): 265-75.
    • (2006) Arch Pharm Res , vol.29 , Issue.4 , pp. 265-275
    • Lee, S.W.1    Kim, W.J.2    Park, J.A.3
  • 44
    • 38849198756 scopus 로고    scopus 로고
    • Radiotherapy and radiosensitizers in the treatment of glioblastoma multiforme
    • Chang JE, Khuntia D, Robins HI, et al. Radiotherapy and radiosensitizers in the treatment of glioblastoma multiforme. Clin Adv Hematol Oncol 2007; 5(11): 894-902, 907-815.
    • (2007) Clin Adv Hematol Oncol , vol.5 , Issue.11
    • Chang, J.E.1    Khuntia, D.2    Robins, H.I.3
  • 45
    • 0035469483 scopus 로고    scopus 로고
    • Current and future developments in the use of temozolomide for the treatment of brain tumours
    • Stupp R, Gander M, Leyvraz S, et al. Current and future developments in the use of temozolomide for the treatment of brain tumours. Lancet Oncol 2001; 2(9): 552-60.
    • (2001) Lancet Oncol , vol.2 , Issue.9 , pp. 552-560
    • Stupp, R.1    Gander, M.2    Leyvraz, S.3
  • 46
    • 40949121607 scopus 로고    scopus 로고
    • ABC multidrug transporters: Structure, function and role in chemoresistance
    • Sharom FJ. ABC multidrug transporters: structure, function and role in chemoresistance. Pharmacogenomics 2008; 9(1): 105-27.
    • (2008) Pharmacogenomics , vol.9 , Issue.1 , pp. 105-127
    • Sharom, F.J.1
  • 47
    • 42149132635 scopus 로고    scopus 로고
    • Chemoresistance in gliomas
    • Lu C, Shervington A. Chemoresistance in gliomas. Mol Cell Biochem 2008; 312(1-2): 71-80.
    • (2008) Mol Cell Biochem , vol.312 , Issue.1-2 , pp. 71-80
    • Lu, C.1    Shervington, A.2
  • 48
    • 62549108159 scopus 로고    scopus 로고
    • ABC transporters, drug resistance, and cancer stem cells
    • Dean M. ABC transporters, drug resistance, and cancer stem cells. J Mammary Gland Biol Neoplasia 2009; 14(1): 3-9.
    • (2009) J Mammary Gland Biol Neoplasia , vol.14 , Issue.1 , pp. 3-9
    • Dean, M.1
  • 49
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005; 5(4): 275-84.
    • (2005) Nat Rev Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 50
    • 4644306516 scopus 로고    scopus 로고
    • A distinct "side population" of cells with high drug efflux capacity in human tumor cells
    • Hirschmann-Jax C, Foster AE, Wulf GG, et al. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A 2004; 101(39): 14228-33.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.39 , pp. 14228-14233
    • Hirschmann-Jax, C.1    Foster, A.E.2    Wulf, G.G.3
  • 51
    • 79955438869 scopus 로고    scopus 로고
    • SALL4, a stem cell factor, affects the side population by regulation of the ATP-binding cassette drug transport genes
    • Jeong HW, Cui W, Yang Y, et al. SALL4, a stem cell factor, affects the side population by regulation of the ATP-binding cassette drug transport genes. PLoS One 2011; 6(4): e18372.
    • (2011) PLoS One , vol.6 , Issue.4
    • Jeong, H.W.1    Cui, W.2    Yang, Y.3
  • 52
    • 0036090222 scopus 로고    scopus 로고
    • Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro
    • Graham SM, Jorgensen HG, Allan E, et al. Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood 2002; 99(1): 319-25.
    • (2002) Blood , vol.99 , Issue.1 , pp. 319-325
    • Graham, S.M.1    Jorgensen, H.G.2    Allan, E.3
  • 53
    • 0344735881 scopus 로고    scopus 로고
    • Cancerous stem cells can arise from pediatric brain tumors
    • Hemmati HD, Nakano I, Lazareff JA, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 2003; 100(25): 15178-83.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.25 , pp. 15178-15183
    • Hemmati, H.D.1    Nakano, I.2    Lazareff, J.A.3
  • 54
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • Galli R, Binda E, Orfanelli U, et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 2004; 64(19): 7011-21.
    • (2004) Cancer Res , vol.64 , Issue.19 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3
  • 55
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004; 432(7015): 396-401.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 56
    • 33748051406 scopus 로고    scopus 로고
    • Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
    • Bao S, Wu Q, Sathornsumetee S, et al. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res 2006; 66(16): 7843-8.
    • (2006) Cancer Res , vol.66 , Issue.16 , pp. 7843-7848
    • Bao, S.1    Wu, Q.2    Sathornsumetee, S.3
  • 57
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serumcultured cell lines
    • Lee J, Kotliarova S, Kotliarov Y, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serumcultured cell lines. Cancer Cell 2006; 9(5): 391-403.
    • (2006) Cancer Cell , vol.9 , Issue.5 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3
  • 58
    • 62849086607 scopus 로고    scopus 로고
    • Autocrine factors sustain glioblastoma stem cell self-renewal
    • Li G, Chen Z, Hu YD, et al. Autocrine factors sustain glioblastoma stem cell self-renewal. Oncol Rep 2009; 21(2): 419-24.
    • (2009) Oncol Rep , vol.21 , Issue.2 , pp. 419-424
    • Li, G.1    Chen, Z.2    Hu, Y.D.3
  • 59
    • 78649986150 scopus 로고    scopus 로고
    • TGF-beta Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma
    • Anido J, Saez-Borderias A, Gonzalez-Junca A, et al. TGF-beta Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma. Cancer Cell 2010; 18(6): 655-68.
    • (2010) Cancer Cell , vol.18 , Issue.6 , pp. 655-668
    • Anido, J.1    Saez-Borderias, A.2    Gonzalez-Junca, A.3
  • 60
    • 33845610993 scopus 로고    scopus 로고
    • Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumourinitiating cells
    • Piccirillo SG, Reynolds BA, Zanetti N, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumourinitiating cells. Nature 2006; 444(7120): 761-5.
    • (2006) Nature , vol.444 , Issue.7120 , pp. 761-765
    • Piccirillo, S.G.1    Reynolds, B.A.2    Zanetti, N.3
  • 61
    • 33846029123 scopus 로고    scopus 로고
    • A perivascular niche for brain tumor stem cells
    • Calabrese C, Poppleton H, Kocak M, et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007; 11(1): 69-82.
    • (2007) Cancer Cell , vol.11 , Issue.1 , pp. 69-82
    • Calabrese, C.1    Poppleton, H.2    Kocak, M.3
  • 62
    • 33947191055 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
    • Vredenburgh JJ, Desjardins A, Herndon JE, et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res 2007; 13(4): 1253-9.
    • (2007) Clin Cancer Res , vol.13 , Issue.4 , pp. 1253-1259
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon, J.E.3
  • 63
    • 36049037819 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
    • Vredenburgh JJ, Desjardins A, Herndon JE, et al. Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol 2007; 25(30): 4722-9.
    • (2007) J Clin Oncol , vol.25 , Issue.30 , pp. 4722-4729
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon, J.E.3
  • 64
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • Friedman HS, Prados MD, Wen PY, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 2009; 27(28): 4733-40.
    • (2009) J Clin Oncol , vol.27 , Issue.28 , pp. 4733-4740
    • Friedman, H.S.1    Prados, M.D.2    Wen, P.Y.3
  • 65
    • 79958217698 scopus 로고    scopus 로고
    • Recurrent spinal cord glioblastoma: Salvage therapy with bevacizumab
    • Chamberlain MC, Johnston SK. Recurrent spinal cord glioblastoma: salvage therapy with bevacizumab. J Neurooncol 2011; 102(3): 427-32.
    • (2011) J Neurooncol , vol.102 , Issue.3 , pp. 427-432
    • Chamberlain, M.C.1    Johnston, S.K.2
  • 66
    • 80052749324 scopus 로고    scopus 로고
    • Retrospective study of dasatinib for recurrent glioblastoma after bevacizumab failure
    • Lu-Emerson C, Norden AD, Drappatz J, et al. Retrospective study of dasatinib for recurrent glioblastoma after bevacizumab failure. J Neurooncol 2011; 104(1): 287-91.
    • (2011) J Neurooncol , vol.104 , Issue.1 , pp. 287-291
    • Lu-Emerson, C.1    Norden, A.D.2    Drappatz, J.3
  • 67
    • 70350142397 scopus 로고    scopus 로고
    • Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
    • Iwamoto FM, Abrey LE, Beal K, et al. Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma. Neurology 2009; 73(15): 1200-6.
    • (2009) Neurology , vol.73 , Issue.15 , pp. 1200-1206
    • Iwamoto, F.M.1    Abrey, L.E.2    Beal, K.3
  • 68
    • 61349199518 scopus 로고    scopus 로고
    • An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma
    • Norden AD, Drappatz J, Muzikansky A, et al. An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma. J Neurooncol 2009; 92(2): 149-55.
    • (2009) J Neurooncol , vol.92 , Issue.2 , pp. 149-155
    • Norden, A.D.1    Drappatz, J.2    Muzikansky, A.3
  • 69
    • 56749136293 scopus 로고    scopus 로고
    • What is the place of bevacizumab and irinotecan in the treatment of glioblastoma and other malignant gliomas?
    • Omuro AM, Delattre JY. What is the place of bevacizumab and irinotecan in the treatment of glioblastoma and other malignant gliomas?. Curr Opin Neurol 2008; 21(6): 717-9.
    • (2008) Curr Opin Neurol , vol.21 , Issue.6 , pp. 717-719
    • Omuro, A.M.1    Delattre, J.Y.2
  • 70
    • 78349252105 scopus 로고    scopus 로고
    • Overview of cellular immunotherapy for patients with glioblastoma
    • Vauleon E, Avril T, Collet B, et al. Overview of cellular immunotherapy for patients with glioblastoma. Clin Dev Immunol 2010; 2010. pii: 689171.
    • (2010) Clin Dev Immunol 2010
    • Vauleon, E.1    Avril, T.2    Collet, B.3
  • 71
    • 78650642294 scopus 로고    scopus 로고
    • Depletion of regulatory T cells facilitates growth of established tumors: A mechanism involving the regulation of myeloid-derived suppressor cells by lipoxin A4
    • Zhang B, Jia H, Liu J, et al. Depletion of regulatory T cells facilitates growth of established tumors: a mechanism involving the regulation of myeloid-derived suppressor cells by lipoxin A4. J Immunol 2010; 185(12): 7199-206.
    • (2010) J Immunol , vol.185 , Issue.12 , pp. 7199-7206
    • Zhang, B.1    Jia, H.2    Liu, J.3
  • 72
    • 78049488087 scopus 로고    scopus 로고
    • Glioma cells display complex cell surface topographies that resist the actions of cytolytic effector lymphocytes
    • Hoa N, Ge L, Kuznetsov Y, et al. Glioma cells display complex cell surface topographies that resist the actions of cytolytic effector lymphocytes. J Immunol 2010; 185(8): 4793-803.
    • (2010) J Immunol , vol.185 , Issue.8 , pp. 4793-4803
    • Hoa, N.1    Ge, L.2    Kuznetsov, Y.3
  • 73
    • 80055118669 scopus 로고    scopus 로고
    • Stem cells in brain tumorigenesis and their impact on therapy
    • Cardona AF, Balana C, Torres D, et al. Stem cells in brain tumorigenesis and their impact on therapy. Curr Stem Cell Res Ther 2011; 6(4): 339-49.
    • (2011) Curr Stem Cell Res Ther , vol.6 , Issue.4 , pp. 339-349
    • Cardona, A.F.1    Balana, C.2    Torres, D.3
  • 74
    • 33747749871 scopus 로고    scopus 로고
    • Angiogenesis in malignant glioma-a target for antitumor therapy?
    • Tuettenberg J, Friedel C, Vajkoczy P. Angiogenesis in malignant glioma-a target for antitumor therapy?. Crit Rev Oncol Hematol 2006; 59(3): 181-93.
    • (2006) Crit Rev Oncol Hematol , vol.59 , Issue.3 , pp. 181-193
    • Tuettenberg, J.1    Friedel, C.2    Vajkoczy, P.3
  • 75
    • 68049093213 scopus 로고    scopus 로고
    • Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy
    • Lucio-Eterovic AK, Piao Y, de Groot JF. Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin Cancer Res 2009; 15(14): 4589-99.
    • (2009) Clin Cancer Res , vol.15 , Issue.14 , pp. 4589-4599
    • Lucio-Eterovic, A.K.1    Piao, Y.2    de Groot, J.F.3
  • 76
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003; 3(6): 401-10.
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 77
    • 77952509640 scopus 로고    scopus 로고
    • Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma
    • Rahman R, Smith S, Rahman C, et al. Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma. J Oncol 2010; 2010: 251231.
    • (2010) J Oncol , vol.2010
    • Rahman, R.1    Smith, S.2    Rahman, C.3
  • 78
    • 34247628429 scopus 로고    scopus 로고
    • Angiogenesis in cancer: Molecular mechanisms, clinical impact
    • Eichhorn ME, Kleespies A, Angele MK, et al. Angiogenesis in cancer: molecular mechanisms, clinical impact. Langenbecks Arch Surg 2007; 392(3): 371-9.
    • (2007) Langenbecks Arch Surg , vol.392 , Issue.3 , pp. 371-379
    • Eichhorn, M.E.1    Kleespies, A.2    Angele, M.K.3
  • 79
    • 77952470629 scopus 로고    scopus 로고
    • Progress on antiangiogenic therapy for patients with malignant glioma
    • Ahluwalia MS, Gladson CL. Progress on antiangiogenic therapy for patients with malignant glioma. J Oncol 2010; 2010: 689018.
    • (2010) J Oncol , vol.2010
    • Ahluwalia, M.S.1    Gladson, C.L.2
  • 80
    • 84862766496 scopus 로고    scopus 로고
    • Glioblastoma angiogenesis: VEGF resistance solutions and new strategies based on molecular mechanisms of tumor vessel formation
    • Takano S. Glioblastoma angiogenesis: VEGF resistance solutions and new strategies based on molecular mechanisms of tumor vessel formation. Brain Tumor Pathol 2012; 29(2): 73-86.
    • (2012) Brain Tumor Pathol , vol.29 , Issue.2 , pp. 73-86
    • Takano, S.1
  • 81
    • 84875640859 scopus 로고    scopus 로고
    • VEGF promotes proliferation of human glioblastoma multiforme stem-like cells through VEGF receptor 2
    • Xu C, Wu X, Zhu J. VEGF promotes proliferation of human glioblastoma multiforme stem-like cells through VEGF receptor 2. ScientificWorldJournal 2013; 2013: 417413.
    • (2013) ScientificWorldJournal , vol.2013
    • Xu, C.1    Wu, X.2    Zhu, J.3
  • 82
    • 77952504774 scopus 로고    scopus 로고
    • Molecular therapeutic targets for glioma angiogenesis
    • Takano S, Yamashita T, Ohneda O. Molecular therapeutic targets for glioma angiogenesis. J Oncol 2010; 2010: 351908.
    • (2010) J Oncol , vol.2010
    • Takano, S.1    Yamashita, T.2    Ohneda, O.3
  • 83
    • 84868035933 scopus 로고    scopus 로고
    • Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype
    • Piao Y, Liang J, Holmes L, et al. Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. Neuro Oncol 2012; 14(11): 1379-92.
    • (2012) Neuro Oncol , vol.14 , Issue.11 , pp. 1379-1392
    • Piao, Y.1    Liang, J.2    Holmes, L.3
  • 84
    • 78650153633 scopus 로고    scopus 로고
    • Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
    • Ricci-Vitiani L, Pallini R, Biffoni M, et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 2010; 468(7325): 824-8.
    • (2010) Nature , vol.468 , Issue.7325 , pp. 824-828
    • Ricci-Vitiani, L.1    Pallini, R.2    Biffoni, M.3
  • 85
    • 77955087620 scopus 로고    scopus 로고
    • Endothelial cell transdifferentiation of human glioma stem progenitor cells in vitro
    • Zhao Y, Dong J, Huang Q, et al. Endothelial cell transdifferentiation of human glioma stem progenitor cells in vitro. Brain Res Bull 2010; 82(5-6): 308-12.
    • (2010) Brain Res Bull , vol.82 , Issue.5-6 , pp. 308-312
    • Zhao, Y.1    Dong, J.2    Huang, Q.3
  • 86
    • 78650098659 scopus 로고    scopus 로고
    • Glioblastoma stem-like cells give rise to tumour endothelium
    • Wang R, Chadalavada K, Wilshire J, et al. Glioblastoma stem-like cells give rise to tumour endothelium. Nature 2010; 468(7325): 829-33.
    • (2010) Nature , vol.468 , Issue.7325 , pp. 829-833
    • Wang, R.1    Chadalavada, K.2    Wilshire, J.3
  • 87
    • 84866340817 scopus 로고    scopus 로고
    • Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications
    • Yang L, Lin C, Wang L, et al. Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications. Exp Cell Res 2012; 318(19): 2417-26.
    • (2012) Exp Cell Res , vol.318 , Issue.19 , pp. 2417-2426
    • Yang, L.1    Lin, C.2    Wang, L.3
  • 88
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston JM, Li Z, McLendon RE, et al. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009; 8(20): 3274-84.
    • (2009) Cell Cycle , vol.8 , Issue.20 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3
  • 89
    • 65249131228 scopus 로고    scopus 로고
    • Brain tumor hypoxia: Tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target
    • Jensen RL. Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target. J Neurooncol 2009; 92(3): 317-35.
    • (2009) J Neurooncol , vol.92 , Issue.3 , pp. 317-335
    • Jensen, R.L.1
  • 90
    • 69349095324 scopus 로고    scopus 로고
    • CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines
    • McCord AM, Jamal M, Williams ES, et al. CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines. Clin Cancer Res 2009; 15(16): 5145-53.
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5145-5153
    • McCord, A.M.1    Jamal, M.2    Williams, E.S.3
  • 91
    • 70449687092 scopus 로고    scopus 로고
    • Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha
    • Soeda A, Park M, Lee D, et al. Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha. Oncogene 2009; 28(45): 3949-59.
    • (2009) Oncogene , vol.28 , Issue.45 , pp. 3949-3959
    • Soeda, A.1    Park, M.2    Lee, D.3
  • 92
    • 77649273107 scopus 로고    scopus 로고
    • Hypoxia inducible factors in cancer stem cells
    • Heddleston JM, Li Z, Lathia JD, et al. Hypoxia inducible factors in cancer stem cells. Br J Cancer 2010; 102(5): 789-95.
    • (2010) Br J Cancer , vol.102 , Issue.5 , pp. 789-795
    • Heddleston, J.M.1    Li, Z.2    Lathia, J.D.3
  • 93
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z, Bao S, Wu Q, et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009; 15(6): 501-13.
    • (2009) Cancer Cell , vol.15 , Issue.6 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3
  • 94
    • 84895920615 scopus 로고    scopus 로고
    • Hypoxia After Liver Surgery Imposes an Aggressive Cancer Stem Cell Phenotype on Residual Tumor Cells
    • Govaert KM, Emmink BL, Nijkamp MW, et al. Hypoxia After Liver Surgery Imposes an Aggressive Cancer Stem Cell Phenotype on Residual Tumor Cells. Ann Surg 2014; 259(4): 750-9.
    • (2014) Ann Surg , vol.259 , Issue.4 , pp. 750-759
    • Govaert, K.M.1    Emmink, B.L.2    Nijkamp, M.W.3
  • 95
    • 84866875005 scopus 로고    scopus 로고
    • Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential
    • Salnikov AV, Liu L, Platen M, et al. Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential. PLoS One 2012; 7(9): e46391.
    • (2012) PLoS One , vol.7 , Issue.9
    • Salnikov, A.V.1    Liu, L.2    Platen, M.3
  • 96
    • 0018125603 scopus 로고
    • Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial
    • Walker MD, Alexander E Jr, Hunt WE, et al. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg 1978; 49(3): 333-43.
    • (1978) J Neurosurg , vol.49 , Issue.3 , pp. 333-343
    • Walker, M.D.1    Alexander, E.2    Hunt, W.E.3
  • 97
    • 51649117107 scopus 로고    scopus 로고
    • Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
    • Hegi ME, Liu L, Herman JG, et al. Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol 2008; 26(25): 4189-99.
    • (2008) J Clin Oncol , vol.26 , Issue.25 , pp. 4189-4199
    • Hegi, M.E.1    Liu, L.2    Herman, J.G.3
  • 98
    • 48649104080 scopus 로고    scopus 로고
    • Temozolomide preferentially depletes cancer stem cells in glioblastoma
    • Beier D, Rohrl S, Pillai DR, et al. Temozolomide preferentially depletes cancer stem cells in glioblastoma. Cancer Res 2008; 68(14): 5706-15.
    • (2008) Cancer Res , vol.68 , Issue.14 , pp. 5706-5715
    • Beier, D.1    Rohrl, S.2    Pillai, D.R.3
  • 99
    • 33846237601 scopus 로고    scopus 로고
    • HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell selfrenewal, and tumorigenicity
    • Clement V, Sanchez P, de Tribolet N, et al. HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell selfrenewal, and tumorigenicity. Curr Biol 2007; 17(2): 165-72.
    • (2007) Curr Biol , vol.17 , Issue.2 , pp. 165-172
    • Clement, V.1    Sanchez, P.2    de Tribolet, N.3
  • 100
    • 63249106377 scopus 로고    scopus 로고
    • Cancer stem cells-new approach to cancerogenensis and treatment
    • Macingova Z, Filip S. Cancer stem cells-new approach to cancerogenensis and treatment. Acta Medica (Hradec Kralove) 2008; 51(3): 139-44.
    • (2008) Acta Medica (Hradec Kralove) , vol.51 , Issue.3 , pp. 139-144
    • Macingova, Z.1    Filip, S.2
  • 101
    • 77349109478 scopus 로고    scopus 로고
    • Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy
    • Sullivan JP, Minna JD, Shay JW. Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy. Cancer Metastasis Rev 2010; 29(1): 61-72.
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.1 , pp. 61-72
    • Sullivan, J.P.1    Minna, J.D.2    Shay, J.W.3
  • 103
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285(21): 1182-6.
    • (1971) N Engl J Med , vol.285 , Issue.21 , pp. 1182-1186
    • Folkman, J.1
  • 104
    • 70449517400 scopus 로고    scopus 로고
    • Antiangiogenic therapies for high-grade glioma
    • Norden AD, Drappatz J, Wen PY. Antiangiogenic therapies for high-grade glioma. Nat Rev Neurol 2009; 5(11): 610-20.
    • (2009) Nat Rev Neurol , vol.5 , Issue.11 , pp. 610-620
    • Norden, A.D.1    Drappatz, J.2    Wen, P.Y.3
  • 105
    • 54249151684 scopus 로고    scopus 로고
    • Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction
    • Das B, Tsuchida R, Malkin D, et al. Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction. Stem Cells 2008; 26(7): 1818-30.
    • (2008) Stem Cells , vol.26 , Issue.7 , pp. 1818-1830
    • Das, B.1    Tsuchida, R.2    Malkin, D.3
  • 106
    • 67349202281 scopus 로고    scopus 로고
    • Effect of hypoxia-inducible factor-1alpha silencing on the sensitivity of human brain glioma cells to doxorubicin and etoposide
    • Chen L, Feng P, Li S, et al. Effect of hypoxia-inducible factor-1alpha silencing on the sensitivity of human brain glioma cells to doxorubicin and etoposide. Neurochem Res 2009; 34(5): 984-90.
    • (2009) Neurochem Res , vol.34 , Issue.5 , pp. 984-990
    • Chen, L.1    Feng, P.2    Li, S.3
  • 107
    • 0030785819 scopus 로고    scopus 로고
    • The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine
    • Blay J, White TD, Hoskin DW. The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine. Cancer Res 1997; 57(13): 2602-5.
    • (1997) Cancer Res , vol.57 , Issue.13 , pp. 2602-2605
    • Blay, J.1    White, T.D.2    Hoskin, D.W.3
  • 108
    • 77957564570 scopus 로고    scopus 로고
    • Extracellular adenosine triphosphate and adenosine in cancer
    • Stagg J, Smyth MJ. Extracellular adenosine triphosphate and adenosine in cancer. Oncogene 2010; 29(39): 5346-58.
    • (2010) Oncogene , vol.29 , Issue.39 , pp. 5346-5358
    • Stagg, J.1    Smyth, M.J.2
  • 109
    • 34347206794 scopus 로고    scopus 로고
    • Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells
    • Merighi S, Benini A, Mirandola P, et al. Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. Mol Pharmacol 2007; 72(1): 162-72.
    • (2007) Mol Pharmacol , vol.72 , Issue.1 , pp. 162-172
    • Merighi, S.1    Benini, A.2    Mirandola, P.3
  • 110
    • 33646909636 scopus 로고    scopus 로고
    • Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells
    • Merighi S, Benini A, Mirandola P, et al. Adenosine modulates vascular endothelial growth factor expression via hypoxiainducible factor-1 in human glioblastoma cells. Biochem Pharmacol 2006; 72(1): 19-31.
    • (2006) Biochem Pharmacol , vol.72 , Issue.1 , pp. 19-31
    • Merighi, S.1    Benini, A.2    Mirandola, P.3
  • 112
    • 0034953105 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M, Hamon Y, Chimini G. The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res 2001; 42(7): 1007-17.
    • (2001) J Lipid Res , vol.42 , Issue.7 , pp. 1007-1017
    • Dean, M.1    Hamon, Y.2    Chimini, G.3
  • 113
    • 0034947674 scopus 로고    scopus 로고
    • From MDR to MXR: New understanding of multidrug resistance systems, their properties and clinical significance
    • Litman T, Druley TE, Stein WD, et al. From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol Life Sci 2001; 58(7): 931-59.
    • (2001) Cell Mol Life Sci , vol.58 , Issue.7 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3
  • 114
    • 0037358040 scopus 로고    scopus 로고
    • Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting p-glycoprotein
    • Thomas H, Coley HM. Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer Control 2003; 10(2): 159-65.
    • (2003) Cancer Control , vol.10 , Issue.2 , pp. 159-165
    • Thomas, H.1    Coley, H.M.2
  • 115
    • 33846215616 scopus 로고    scopus 로고
    • A primer on the mechanics of Pglycoprotein the multidrug transporter
    • Hennessy M, Spiers JP. A primer on the mechanics of Pglycoprotein the multidrug transporter. Pharmacol Res 2007; 55(1): 1-15.
    • (2007) Pharmacol Res , vol.55 , Issue.1 , pp. 1-15
    • Hennessy, M.1    Spiers, J.P.2
  • 116
  • 117
    • 29244441701 scopus 로고    scopus 로고
    • ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier
    • Bronger H, Konig J, Kopplow K, et al. ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier. Cancer Res 2005; 65(24): 11419-28.
    • (2005) Cancer Res , vol.65 , Issue.24 , pp. 11419-11428
    • Bronger, H.1    Konig, J.2    Kopplow, K.3
  • 118
    • 26944461925 scopus 로고    scopus 로고
    • Expression of drug resistance proteins Pgp, MRP1, MRP3, MRP5 and GST-pi in human glioma
    • Calatozzolo C, Gelati M, Ciusani E, et al. Expression of drug resistance proteins Pgp, MRP1, MRP3, MRP5 and GST-pi in human glioma. J Neurooncol 2005; 74(2): 113-21.
    • (2005) J Neurooncol , vol.74 , Issue.2 , pp. 113-121
    • Calatozzolo, C.1    Gelati, M.2    Ciusani, E.3
  • 119
    • 1342287139 scopus 로고    scopus 로고
    • Multidrug resistanceassociated protein MRP1 expression in human gliomas: Chemosensitization to vincristine and etoposide by indomethacin in human glioma cell lines overexpressing MRP1
    • Benyahia B, Huguet S, Decleves X, et al. Multidrug resistanceassociated protein MRP1 expression in human gliomas: chemosensitization to vincristine and etoposide by indomethacin in human glioma cell lines overexpressing MRP1. J Neurooncol 2004; 66(1-2): 65-70.
    • (2004) J Neurooncol , vol.66 , Issue.1-2 , pp. 65-70
    • Benyahia, B.1    Huguet, S.2    Decleves, X.3
  • 120
    • 0032744001 scopus 로고    scopus 로고
    • Structural, mechanistic and clinical aspects of MRP1
    • Hipfner DR, Deeley RG, Cole SP. Structural, mechanistic and clinical aspects of MRP1. Biochim Biophys Acta 1999; 1461(2): 359-376.
    • (1999) Biochim Biophys Acta , vol.1461 , Issue.2 , pp. 359-376
    • Hipfner, D.R.1    Deeley, R.G.2    Cole, S.P.3
  • 121
    • 0027960078 scopus 로고
    • Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells
    • Cole SP, Sparks KE, Fraser K, et al. Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. Cancer Res 1994; 54(22): 5902-5910.
    • (1994) Cancer Res , vol.54 , Issue.22 , pp. 5902-5910
    • Cole, S.P.1    Sparks, K.E.2    Fraser, K.3
  • 122
    • 0035682486 scopus 로고    scopus 로고
    • MRP subfamily transporters and resistance to anticancer agents
    • Kruh GD, Zeng H, Rea PA, et al. MRP subfamily transporters and resistance to anticancer agents. J Bioenerg Biomembr 2001; 33(6): 493-501.
    • (2001) J Bioenerg Biomembr , vol.33 , Issue.6 , pp. 493-501
    • Kruh, G.D.1    Zeng, H.2    Rea, P.A.3
  • 123
    • 0035824674 scopus 로고    scopus 로고
    • Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3)
    • Zelcer N, Saeki T, Reid G, et al. Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J Biol Chem 2001; 276(49): 46400-07.
    • (2001) J Biol Chem , vol.276 , Issue.49 , pp. 46400-46407
    • Zelcer, N.1    Saeki, T.2    Reid, G.3
  • 124
    • 0036471128 scopus 로고    scopus 로고
    • Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues
    • Lai L, Tan T. M. Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues. Biochem J 2002; 361(Pt 3): 497-503.
    • (2002) Biochem J , vol.361 , pp. 497-503
    • Lai, L.1    Tan, T.M.2
  • 125
    • 0034730755 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
    • Jedlitschky G, Burchell B, Keppler D. The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Biol Chem 2000; 275(39): 30069-74.
    • (2000) J Biol Chem , vol.275 , Issue.39 , pp. 30069-30074
    • Jedlitschky, G.1    Burchell, B.2    Keppler, D.3
  • 126
    • 20544436363 scopus 로고    scopus 로고
    • Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain
    • Aronica E, Gorter JA, Redeker S, et al. Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain. Epilepsia 2005; 46(6): 849-57.
    • (2005) Epilepsia , vol.46 , Issue.6 , pp. 849-857
    • Aronica, E.1    Gorter, J.A.2    Redeker, S.3
  • 127
    • 33947580644 scopus 로고    scopus 로고
    • Human multidrug transporter ABCG2, a target for sensitizing drug resistance in cancer chemotherapy
    • Xu J, Peng H, Zhang JT. Human multidrug transporter ABCG2, a target for sensitizing drug resistance in cancer chemotherapy. Curr Med Chem 2007; 14(6): 689-701.
    • (2007) Curr Med Chem , vol.14 , Issue.6 , pp. 689-701
    • Xu, J.1    Peng, H.2    Zhang, J.T.3
  • 128
    • 0041492605 scopus 로고    scopus 로고
    • Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity
    • Awasthi S, Singhal SS, Singhal J, et al. Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity. Int J Oncol 2003; 22(4): 721-32.
    • (2003) Int J Oncol , vol.22 , Issue.4 , pp. 721-732
    • Awasthi, S.1    Singhal, S.S.2    Singhal, J.3
  • 129
    • 33747288211 scopus 로고    scopus 로고
    • Cellular functions of vaults and their involvement in multidrug resistance
    • Steiner E, Holzmann K, Elbling L, et al. Cellular functions of vaults and their involvement in multidrug resistance. Curr Drug Targets 2006; 7(8): 923-34.
    • (2006) Curr Drug Targets , vol.7 , Issue.8 , pp. 923-934
    • Steiner, E.1    Holzmann, K.2    Elbling, L.3
  • 130
    • 33751263449 scopus 로고    scopus 로고
    • A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer
    • O'Connor R, O'Leary M, Ballot J, et al. A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer. Cancer Chemother Pharmacol 2007; 59(1): 79-87.
    • (2007) Cancer Chemother Pharmacol , vol.59 , Issue.1 , pp. 79-87
    • O'Connor, R.1    O'Leary, M.2    Ballot, J.3
  • 131
    • 39749135394 scopus 로고    scopus 로고
    • Inhibition of Pglycoprotein (ABCB1)-and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R))
    • Robey RW, Shukla S, Finley EM, et al. Inhibition of Pglycoprotein (ABCB1)-and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)). Biochem Pharmacol 2008; 75(6): 1302-12.
    • (2008) Biochem Pharmacol , vol.75 , Issue.6 , pp. 1302-1312
    • Robey, R.W.1    Shukla, S.2    Finley, E.M.3
  • 132
    • 0035876039 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin
    • Peck RA, Hewett J, Harding MW, et al. Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin. J Clin Oncol 2001; 19(12): 3130-41.
    • (2001) J Clin Oncol , vol.19 , Issue.12 , pp. 3130-3141
    • Peck, R.A.1    Hewett, J.2    Harding, M.W.3
  • 133
    • 57049110485 scopus 로고    scopus 로고
    • Differences in the expression pattern of P-glycoprotein and MRP1 in low-grade and high-grade gliomas
    • de Faria GP, de Oliveira JA, de Oliveira JG, et al. Differences in the expression pattern of P-glycoprotein and MRP1 in low-grade and high-grade gliomas. Cancer Invest 2008; 26(9): 883-9.
    • (2008) Cancer Invest , vol.26 , Issue.9 , pp. 883-889
    • de Faria, G.P.1    de Oliveira, J.A.2    de Oliveira, J.G.3
  • 134
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • Zhou S, Schuetz JD, Bunting KD, et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001; 7(9): 1028-34.
    • (2001) Nat Med , vol.7 , Issue.9 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3
  • 135
    • 0345600069 scopus 로고    scopus 로고
    • Hematopoietic cells from mice that are deficient in both Bcrp1/Abcg2 and Mdr1a/1b develop normally but are sensitized to mitoxantrone
    • Zhou S, Zong Y, Lu T, et al. Hematopoietic cells from mice that are deficient in both Bcrp1/Abcg2 and Mdr1a/1b develop normally but are sensitized to mitoxantrone. Biotechniques 2003; 35(6): 1248-52.
    • (2003) Biotechniques , vol.35 , Issue.6 , pp. 1248-1252
    • Zhou, S.1    Zong, Y.2    Lu, T.3
  • 136
    • 36049008358 scopus 로고    scopus 로고
    • Bone morphogenetic proteins regulate tumorigenicity in human glioblastoma stem cells
    • Piccirillo SG, Vescovi AL. Bone morphogenetic proteins regulate tumorigenicity in human glioblastoma stem cells. Ernst Schering Found Symp Proc 2006; 5: 59-81.
    • (2006) Ernst Schering Found Symp Proc , vol.5 , pp. 59-81
    • Piccirillo, S.G.1    Vescovi, A.L.2
  • 137
    • 77955158299 scopus 로고    scopus 로고
    • The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research
    • Wan F, Zhang S, Xie R, et al. The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research. Brain Pathol 2010; 20(5): 877-89.
    • (2010) Brain Pathol , vol.20 , Issue.5 , pp. 877-889
    • Wan, F.1    Zhang, S.2    Xie, R.3
  • 138
    • 78049303163 scopus 로고    scopus 로고
    • Downregulation of ABCG2 expression in glioblastoma cancer stem cells with miRNA-328 may decrease their chemoresistance
    • Li WQ, Li YM, Tao BB, et al. Downregulation of ABCG2 expression in glioblastoma cancer stem cells with miRNA-328 may decrease their chemoresistance. Med Sci Monit 2010; 16(10): HY27-30.
    • (2010) Med Sci Monit , vol.16 , Issue.10 , pp. 27-30
    • Li, W.Q.1    Li, Y.M.2    Tao, B.B.3
  • 139
    • 69049110880 scopus 로고    scopus 로고
    • ABCG2 is related with the grade of glioma and resistance to mitoxantone, a chemotherapeutic drug for glioma
    • Jin Y, Bin ZQ, Qiang H, et al. ABCG2 is related with the grade of glioma and resistance to mitoxantone, a chemotherapeutic drug for glioma. J Cancer Res Clin Oncol 2009; 135(10): 1369-76.
    • (2009) J Cancer Res Clin Oncol , vol.135 , Issue.10 , pp. 1369-1376
    • Jin, Y.1    Bin, Z.Q.2    Qiang, H.3
  • 140
    • 84864720900 scopus 로고    scopus 로고
    • MGMT hypermethylation and MDR system in glioblastoma cancer stem cells
    • Caldera V, Mellai M, Annovazzi L, et al. MGMT hypermethylation and MDR system in glioblastoma cancer stem cells. Cancer Genomics Proteomics 2012; 9(4): 171-8.
    • (2012) Cancer Genomics Proteomics , vol.9 , Issue.4 , pp. 171-178
    • Caldera, V.1    Mellai, M.2    Annovazzi, L.3
  • 141
    • 84871999193 scopus 로고    scopus 로고
    • Study of chemoresistant CD133+ cancer stem cells from human glioblastoma cell line U138MG using multiple assays
    • Warrier S, Pavanram P, Raina D, et al. Study of chemoresistant CD133+ cancer stem cells from human glioblastoma cell line U138MG using multiple assays. Cell Biol Int 2012; 36(12): 1137-43.
    • (2012) Cell Biol Int , vol.36 , Issue.12 , pp. 1137-1143
    • Warrier, S.1    Pavanram, P.2    Raina, D.3
  • 142
    • 70350150304 scopus 로고    scopus 로고
    • Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma
    • Nakai E, Park K, Yawata T, et al. Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma. Cancer Invest 2009; 27(9): 901-8.
    • (2009) Cancer Invest , vol.27 , Issue.9 , pp. 901-908
    • Nakai, E.1    Park, K.2    Yawata, T.3
  • 143
    • 79953006501 scopus 로고    scopus 로고
    • Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme
    • Broadley KW, Hunn MK, Farrand KJ, et al. Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme. Stem Cells 2011; 29(3): 452-61.
    • (2011) Stem Cells , vol.29 , Issue.3 , pp. 452-461
    • Broadley, K.W.1    Hunn, M.K.2    Farrand, K.J.3
  • 144
    • 33748421262 scopus 로고    scopus 로고
    • Adenosine metabolism and cancer. Focus on "Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatases and reducing ERK1/2 activity via a novel pathway"
    • Linden J. Adenosine metabolism and cancer. Focus on "Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatases and reducing ERK1/2 activity via a novel pathway". Am J Physiol Cell Physiol 2006; 291(3): C405-406.
    • (2006) Am J Physiol Cell Physiol , vol.291 , Issue.3 , pp. 405-406
    • Linden, J.1
  • 145
    • 0032835596 scopus 로고    scopus 로고
    • Trophic effects of purines in neurons and glial cells
    • Rathbone MP, Middlemiss PJ, Gysbers JW, et al. Trophic effects of purines in neurons and glial cells. Prog Neurobiol 1999; 59(6): 663-90.
    • (1999) Prog Neurobiol , vol.59 , Issue.6 , pp. 663-690
    • Rathbone, M.P.1    Middlemiss, P.J.2    Gysbers, J.W.3
  • 146
    • 0038128250 scopus 로고    scopus 로고
    • Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways
    • Picher M, Burch LH, Hirsh AJ, et al. Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways. J Biol Chem 2003; 278(15): 13468-79.
    • (2003) J Biol Chem , vol.278 , Issue.15 , pp. 13468-13479
    • Picher, M.1    Burch, L.H.2    Hirsh, A.J.3
  • 147
    • 77955750932 scopus 로고    scopus 로고
    • CD73: A novel target for cancer immunotherapy
    • Zhang B. CD73: a novel target for cancer immunotherapy. Cancer Res 2010; 70(16): 6407-11.
    • (2010) Cancer Res , vol.70 , Issue.16 , pp. 6407-6411
    • Zhang, B.1
  • 148
    • 0032902151 scopus 로고    scopus 로고
    • An ecto-nucleotide pyrophosphatase is one of the main enzymes involved in the extracellular metabolism of ATP in rat C6 glioma
    • Grobben B, Anciaux K, Roymans D, et al. An ecto-nucleotide pyrophosphatase is one of the main enzymes involved in the extracellular metabolism of ATP in rat C6 glioma. J Neurochem 1999; 72(2): 826-34.
    • (1999) J Neurochem , vol.72 , Issue.2 , pp. 826-834
    • Grobben, B.1    Anciaux, K.2    Roymans, D.3
  • 149
    • 55649124110 scopus 로고    scopus 로고
    • The role of ecto-5'-nucleotidase/CD73 in glioma cell line proliferation
    • Bavaresco L, Bernardi A, Braganhol E, et al. The role of ecto-5'-nucleotidase/CD73 in glioma cell line proliferation. Mol Cell Biochem 2008; 319(1-2): 61-8.
    • (2008) Mol Cell Biochem , vol.319 , Issue.1-2 , pp. 61-68
    • Bavaresco, L.1    Bernardi, A.2    Braganhol, E.3
  • 150
    • 0032782011 scopus 로고    scopus 로고
    • Expression of CD73 (ecto-5'-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry
    • Ludwig HC, Rausch S, Schallock K, et al. Expression of CD73 (ecto-5'-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry. Anticancer Res 1999; 19(3A): 1747-52.
    • (1999) Anticancer Res , vol.19 , Issue.3 A , pp. 1747-1752
    • Ludwig, H.C.1    Rausch, S.2    Schallock, K.3
  • 151
    • 75949112218 scopus 로고    scopus 로고
    • Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
    • Stagg J, Divisekera U, McLaughlin N, et al. Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis. Proc Natl Acad Sci USA 2010; 107(4): 1547-52.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.4 , pp. 1547-1552
    • Stagg, J.1    Divisekera, U.2    McLaughlin, N.3
  • 152
    • 78449305587 scopus 로고    scopus 로고
    • RNAi-mediated CD73 suppression induces apoptosis and cell-cycle arrest in human breast cancer cells
    • Zhi X, Wang Y, Zhou X, et al. RNAi-mediated CD73 suppression induces apoptosis and cell-cycle arrest in human breast cancer cells. Cancer Sci 2010; 101(12): 2561-9.
    • (2010) Cancer Sci , vol.101 , Issue.12 , pp. 2561-2569
    • Zhi, X.1    Wang, Y.2    Zhou, X.3
  • 153
    • 38649133357 scopus 로고    scopus 로고
    • Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells
    • Wang L, Zhou X, Zhou T, et al. Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells. J Cancer Res Clin Oncol 2008; 134(3): 365-72.
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.3 , pp. 365-372
    • Wang, L.1    Zhou, X.2    Zhou, T.3
  • 154
    • 34548008177 scopus 로고    scopus 로고
    • Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo
    • Zhou X, Zhi X, Zhou P, et al. Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo. Oncol Rep 2007; 17(6): 1341-6.
    • (2007) Oncol Rep , vol.17 , Issue.6 , pp. 1341-1346
    • Zhou, X.1    Zhi, X.2    Zhou, P.3
  • 155
    • 84891824680 scopus 로고    scopus 로고
    • Anti-CD73 therapy impairs tumor angiogenesis
    • Allard B, Turcotte M, Spring K, et al. Anti-CD73 therapy impairs tumor angiogenesis. Int J Cancer 2014; 134(6): 1466-73.
    • (2014) Int J Cancer , vol.134 , Issue.6 , pp. 1466-1473
    • Allard, B.1    Turcotte, M.2    Spring, K.3
  • 156
    • 79954576658 scopus 로고    scopus 로고
    • CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis
    • Stagg J, Divisekera U, Duret H, et al. CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis. Cancer Res 2011; 71(8): 2892-900.
    • (2011) Cancer Res , vol.71 , Issue.8 , pp. 2892-2900
    • Stagg, J.1    Divisekera, U.2    Duret, H.3
  • 157
    • 0029835821 scopus 로고    scopus 로고
    • Evidence for the involvement of ecto-5'-nucleotidase (CD73) in drug resistance
    • Ujhazy P, Berleth ES, Pietkiewicz JM, et al. Evidence for the involvement of ecto-5'-nucleotidase (CD73) in drug resistance. Int J Cancer 1996; 68(4): 493-500.
    • (1996) Int J Cancer , vol.68 , Issue.4 , pp. 493-500
    • Ujhazy, P.1    Berleth, E.S.2    Pietkiewicz, J.M.3
  • 158
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm BB, AP IJ, Jacobson KA, et al. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 2001; 53(4): 527-52.
    • (2001) Pharmacol Rev , vol.53 , Issue.4 , pp. 527-552
    • Fredholm, B.B.A.P.I.J.1    Jacobson, K.A.2
  • 159
    • 27944492352 scopus 로고    scopus 로고
    • Gestational diabetes and the adenosine/L-arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium
    • San Martin R, Sobrevia L. Gestational diabetes and the adenosine/L-arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium. Placenta 2006; 27(1): 1-10.
    • (2006) Placenta , vol.27 , Issue.1 , pp. 1-10
    • San Martin, R.1    Sobrevia, L.2
  • 160
    • 33748994847 scopus 로고    scopus 로고
    • A1 adenosine receptors in microglia control glioblastoma-host interaction
    • Synowitz M, Glass R, Farber K, et al. A1 adenosine receptors in microglia control glioblastoma-host interaction. Cancer Res 2006; 66(17): 8550-7.
    • (2006) Cancer Res , vol.66 , Issue.17 , pp. 8550-8557
    • Synowitz, M.1    Glass, R.2    Farber, K.3
  • 161
    • 36549081419 scopus 로고    scopus 로고
    • The A3 adenosine receptor: An enigmatic player in cell biology
    • Gessi S, Merighi S, Varani K, et al. The A3 adenosine receptor: an enigmatic player in cell biology. Pharmacol Ther 2008; 117(1): 123-40.
    • (2008) Pharmacol Ther , vol.117 , Issue.1 , pp. 123-140
    • Gessi, S.1    Merighi, S.2    Varani, K.3
  • 162
    • 0141459429 scopus 로고    scopus 로고
    • Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines
    • Morrone FB, Jacques-Silva MC, Horn AP, et al. Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines. J Neurooncol 2003; 64(3): 211-8.
    • (2003) J Neurooncol , vol.64 , Issue.3 , pp. 211-218
    • Morrone, F.B.1    Jacques-Silva, M.C.2    Horn, A.P.3
  • 163
    • 77953486951 scopus 로고    scopus 로고
    • A3 receptor ligands: Past, present and future trends
    • Taliani S, Pugliesi I, Bellandi M, et al. A3 receptor ligands: past, present and future trends. Curr Top Med Chem 2010; 10(10): 942-75.
    • (2010) Curr Top Med Chem , vol.10 , Issue.10 , pp. 942-975
    • Taliani, S.1    Pugliesi, I.2    Bellandi, M.3
  • 164
    • 77649181282 scopus 로고    scopus 로고
    • Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors
    • Gessi S, Sacchetto V, Fogli E, et al. Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors. Biochem Pharmacol 2010; 79(10): 1483-95.
    • (2010) Biochem Pharmacol , vol.79 , Issue.10 , pp. 1483-1495
    • Gessi, S.1    Sacchetto, V.2    Fogli, E.3
  • 165
    • 33644877968 scopus 로고    scopus 로고
    • A3 adenosine receptors modulate hypoxia-inducible factor-1alpha expression in human A375 melanoma cells
    • Merighi S, Benini A, Mirandola P, et al. A3 adenosine receptors modulate hypoxia-inducible factor-1alpha expression in human A375 melanoma cells. Neoplasia 2005; 7(10): 894-903.
    • (2005) Neoplasia , vol.7 , Issue.10 , pp. 894-903
    • Merighi, S.1    Benini, A.2    Mirandola, P.3
  • 166
    • 34547178922 scopus 로고    scopus 로고
    • Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells
    • Merighi S, Benini A, Mirandola P, et al. Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells. Mol Pharmacol 2007; 72(2): 395-406.
    • (2007) Mol Pharmacol , vol.72 , Issue.2 , pp. 395-406
    • Merighi, S.1    Benini, A.2    Mirandola, P.3
  • 167
    • 84893191712 scopus 로고    scopus 로고
    • The HIF-2alpha dependent induction of PAP and adenosine synthesis regulates glioblastoma stem cell function through the A2B adenosine receptor
    • Liu TZ, Wang X, Bai YF, et al. The HIF-2alpha dependent induction of PAP and adenosine synthesis regulates glioblastoma stem cell function through the A2B adenosine receptor. Int J Biochem Cell Biol 2014; 49: 8-16.
    • (2014) Int J Biochem Cell Biol , vol.49 , pp. 8-16
    • Liu, T.Z.1    Wang, X.2    Bai, Y.F.3
  • 168
    • 53049093740 scopus 로고    scopus 로고
    • Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine
    • Zylka MJ, Sowa NA, Taylor-Blake B, et al. Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine. Neuron 2008; 60(1): 111-22.
    • (2008) Neuron , vol.60 , Issue.1 , pp. 111-122
    • Zylka, M.J.1    Sowa, N.A.2    Taylor-Blake, B.3
  • 169
    • 84890222150 scopus 로고    scopus 로고
    • Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis
    • Lotsch D, Steiner E, Holzmann K, et al. Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis. Oncotarget 2013; 4(11): 1904-18.
    • (2013) Oncotarget , vol.4 , Issue.11 , pp. 1904-1918
    • Lotsch, D.1    Steiner, E.2    Holzmann, K.3
  • 170
    • 77956461668 scopus 로고    scopus 로고
    • MRP3: A molecular target for human glioblastoma multiforme immunotherapy
    • Kuan CT, Wakiya K, Herndon JE, et al. MRP3: a molecular target for human glioblastoma multiforme immunotherapy. BMC Cancer 2010; 10: 468.
    • (2010) BMC Cancer , vol.10 , pp. 468
    • Kuan, C.T.1    Wakiya, K.2    Herndon, J.E.3
  • 171
    • 11144264060 scopus 로고    scopus 로고
    • Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells
    • Kang YH, Lee E, Youk HJ, et al. Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells. Cancer Lett 2005; 217(2): 181-90.
    • (2005) Cancer Lett , vol.217 , Issue.2 , pp. 181-190
    • Kang, Y.H.1    Lee, E.2    Youk, H.J.3
  • 172
    • 0037051092 scopus 로고    scopus 로고
    • Molecular and functional MDR1-Pgp and MRPs expression in human glioblastoma multiforme cell lines
    • Decleves X, Fajac A, Lehmann-Che J, et al. Molecular and functional MDR1-Pgp and MRPs expression in human glioblastoma multiforme cell lines. Int J Cancer 2002; 98(2): 173-80.
    • (2002) Int J Cancer , vol.98 , Issue.2 , pp. 173-180
    • Decleves, X.1    Fajac, A.2    Lehmann-Che, J.3
  • 173
    • 84883192286 scopus 로고    scopus 로고
    • Synergy between the ectoenzymes CD39 and CD73 contributes to adenosinergic immunosuppression in human malignant gliomas
    • Xu S, Shao QQ, Sun JT, et al. Synergy between the ectoenzymes CD39 and CD73 contributes to adenosinergic immunosuppression in human malignant gliomas. Neuro Oncol 2013; 15(9): 1160-72.
    • (2013) Neuro Oncol , vol.15 , Issue.9 , pp. 1160-1172
    • Xu, S.1    Shao, Q.Q.2    Sun, J.T.3
  • 174
    • 83555164934 scopus 로고    scopus 로고
    • Involvement of ecto-5'-nucleotidase/CD73 in U138MG glioma cell adhesion
    • Cappellari AR, Vasques GJ, Bavaresco L, et al. Involvement of ecto-5'-nucleotidase/CD73 in U138MG glioma cell adhesion. Mol Cell Biochem 2012; 359(1-2): 315-22.
    • (2012) Mol Cell Biochem , vol.359 , Issue.1-2 , pp. 315-322
    • Cappellari, A.R.1    Vasques, G.J.2    Bavaresco, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.