The HIF-2alpha dependent induction of PAP and adenosine synthesis regulates glioblastoma stem cell function through the A2B adenosine receptor

International Journal of Biochemistry and Cell Biology

Volumn 49, Issue 1, 2014, Pages 8-16

  Liu, Tian Zhu ^a   Wang, Xin ^a   Bai, Yi Feng ^b   Liao, Hong Zhan ^a   Qiu, Sheng Cong ^a   Yang, Ye Qing ^c   Yan, Xiao Hui ^a   Chen, Jian ^a   Guo, Hong Bo ^a   Zhang, Shi Zhong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c Central Hospital   (China)

Author keywords

A2B receptors; Adenosine; Glioblastoma stem cells; Hypoxia; Prostatic acid phosphatase

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; ADENOSINE; ADENOSINE A2B RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; 1-PROPYL-8-(4-SULFOPHENYL)XANTHINE; ADENOSINE A2 RECEPTOR ANTAGONIST; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE; XANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CARCINOGENESIS; CELL FUNCTION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; GLIOBLASTOMA; GLIOBLASTOMA STEM CELL; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFANT; MALE; NEURAL STEM CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; SYNTHESIS; TUMOR GROWTH; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL HYPOXIA; DRUG EFFECTS; DRUG SCREENING; GENETICS; METABOLISM; NUDE RAT; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; TUMOR CELL CULTURE; TUMOR CELL LINE; WESTERN BLOTTING;

ADENOSINE; ADENOSINE A2 RECEPTOR ANTAGONISTS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GLIOBLASTOMA; HUMANS; MALE; NEOPLASTIC STEM CELLS; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, NUDE; RECEPTOR, ADENOSINE A2B; RNA INTERFERENCE; TUMOR CELLS, CULTURED; XANTHINES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84893191712     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.01.007     Document Type: Article

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