Chimotherapeutic treatment of gliomas increases the amount of cancer stem-like cells;Le traitement du gliome par les agents chimiothérapeutiques favorise la survie des cellules souches tumorales

Medecine/Sciences

Volumn 25, Issue 10, 2009, Pages 775-777

  Bleau, Anne Marie ^a   Holland, Eric C ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TEMOZOLOMIDE;

CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STEM CELL; CARCINOGENESIS; ENDOTHELIUM CELL; GENE; GLIOBLASTOMA; GLIOMA; HUMAN; IN VIVO STUDY; NOTE; PHENOTYPE; PROTEIN EXPRESSION;

EID: 70350317445     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20092510775     Document Type: Note

References (8)

1. Bleau AM, Hambardzumyan D, Ozawa T, et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 2009 ; 4 : 226-235
2. Regenbrecht CR, Lehrach H, Adjaye J. Stemming cancer: functional genomics of cancer stem cells in solid tumors. Stem Cell Rev 2008 ; 4 : 319-328
3. Boo S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Mature 2006 ; 444 : 756-760 (Pubitemid 44949604)
4. Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005 ; 5 : 275-284 (Pubitemid 40488633)
5. Hirschmann-Jax C, Foster AE, Wulf GG, et al. A distinct side population of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci USA 2004 ; 101 : 14228-14233 (Pubitemid 39305058)
6. Goodell MA, Brose K, Paradis G, et al. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996 ; 183 : 1797-1806 (Pubitemid 26134320)
7. Shih AH, Dai C, Hu X, et at. Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res 2004 ; 64 : 4783-4789
8. McConville P, Hambardzumyan D, MoodyJB, et al. Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma. Clin Cancer Res 2007 ; 13 : 2897-2904 (Pubitemid 46849564)