Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use

Nature Protocols

Volumn 10, Issue 1, 2015, Pages 90-105

  Hagemeyer, Christoph E ^a,b   Alt, Karen ^a   Johnston, Angus P R ^b   Such, Georgina K ^c   Ta, Hang T ^a,d   Leung, Melissa K M ^c   Prabhu, Sandeep ^a,b   Wang, Xiaowei ^a,b   Caruso, Frank ^c   Peter, Karlheinz ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE; IRON OXIDE; MACROGOL; POLYMETHACRYLIC ACID; POVIDONE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SORTASE; SORTASE A; UNCLASSIFIED DRUG; AMINOACYLTRANSFERASE; BACTERIAL PROTEIN; CYSTEINE PROTEINASE; MACROGOL DERIVATIVE; NANOPARTICLE; POLY(N-VINYLPYRROLIDINE); POLYMETHACRYLIC ACID DERIVATIVE; POLYVINYL DERIVATIVE; PYRROLIDINE DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL MODIFICATION; DNA EXTRACTION; DRUG CAPSULE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; ESCHERICHIA COLI; HYDROGEN BOND; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DIAGNOSTIC USE; METABOLISM; MOLECULAR IMAGING; PROCEDURES;

AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; CYSTEINE ENDOPEPTIDASES; DRUG DELIVERY SYSTEMS; HYDROGEN BONDING; MOLECULAR IMAGING; MOLECULAR STRUCTURE; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; POLYVINYLS; PYRROLIDINES; SINGLE-CHAIN ANTIBODIES;

EID: 84925937848     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2014.177     Document Type: Article

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