Enzymatic single-chain antibody tagging: A universal approach to targeted molecular imaging and cell homing in cardiovascular disease

Circulation Research

Volumn 109, Issue 4, 2011, Pages 365-373

  Ta, H T ^a   Prabhu, S ^a,b   Leitner, E ^a   Jia, F ^a   Von Elverfeldt, D ^d   Jackson, Katherine E ^a   Heidt, T ^d   Nair, A K N ^a,c   Pearce, H ^a   Von Zur Muhlen, C ^d   Wang, X ^a,b   Peter, K ^a,b   Hagemeyer, C E ^a,b,c  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

antibodies; cell therapy; molecular imaging; platelets; sortase A; targeted molecular therapy; thrombosis

Indexed keywords

CONTRAST MEDIUM; ENHANCED GREEN FLUORESCENT PROTEIN; IRON OXIDE; MICROPARTICLES OF IRON OXIDE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SORTASE; SORTASE A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELL ADHESION; CELL HOMING; CELL REGENERATION; CELL SPECIFICITY; CONJUGATION; CONTROLLED STUDY; INFLAMMATION; INTRAVITAL MICROSCOPY; MICROSCOPY; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOSIS;

AMINOACYLTRANSFERASES; ANIMALS; BACTERIAL PROTEINS; BLOOD PLATELETS; CELL MOVEMENT; CELL TRACKING; CHLORIDES; CHO CELLS; CONTRAST MEDIA; CRICETINAE; CRICETULUS; CYSTEINE ENDOPEPTIDASES; DISEASE MODELS, ANIMAL; FERRIC COMPOUNDS; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MICE; MICE, INBRED C57BL; MICROSCOPY, VIDEO; MOLECULAR PROBE TECHNIQUES; PLATELET ACTIVATION; RECOMBINANT FUSION PROTEINS; SINGLE-CHAIN ANTIBODIES; THROMBOSIS;

EID: 80051787417     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.249375     Document Type: Article

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