Noncanonical STAT3 activation regulates excess TGF-β1 and collagen I expression in muscle of stricturing Crohn's disease

Journal of Immunology

Volumn 194, Issue 7, 2015, Pages 3422-3431

  Li, Chao ^a   Iness, Audra ^a   Yoon, Jennifer ^a   Grider, John R ^a   Murthy, Karnam S ^a   Kellum, John M ^a   Kuemmerle, John F ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; INTERLEUKIN 6; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSFORMING GROWTH FACTOR BETA1; TRINITROBENZENESULFONIC ACID; COLLAGEN TYPE I, ALPHA 1 CHAIN; CYTOKINE; PROTEIN BINDING;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; CTGF GENE; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; INTESTINAL FIBROSIS; INTESTINE MUSCLE; LUCIFERASE ASSAY; MALE; MIDDLE AGED; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ULCERATIVE COLITIS; YOUNG ADULT; ADOLESCENT; AGED; ANIMAL; CHEMICALLY INDUCED; COLITIS; DISEASE MODEL; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; INTESTINE; METABOLISM; MUSCLE; MUTATION; PATHOLOGY; PHOSPHORYLATION; PROMOTER REGION; REPORTER GENE; SMOOTH MUSCLE;

ADOLESCENT; ADULT; AGED; ANIMALS; COLITIS; COLLAGEN TYPE I; CONNECTIVE TISSUE GROWTH FACTOR; CROHN DISEASE; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; FIBROSIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; INTESTINES; MALE; MICE; MIDDLE AGED; MUSCLE, SMOOTH; MUSCLES; MUTATION; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA1; YOUNG ADULT;

EID: 84925877415     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401779     Document Type: Article

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