Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 50, 2010, Pages 21499-21504

  Yang, Jinbo ^a,b   Huang, Jing ^c   Dasgupta, Maupali ^b   Sears, Nathan ^b   Miyagi, Masaru ^d   Wang, Benlian ^d   Chance, Mark R ^d   Chen, Xing ^a   Du, Yuping ^a   Wang, Yuxin ^a   An, Lizhe ^a   Wang, Qin ^a   Lu, Tao ^b   Zhang, Xiaodong ^e   Wang, Zhenghe ^e   Stark, George R ^b,e  

^a LANZHOU UNIVERSITY   (China)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Gene regulation; Posttranslational modifications; Signal transduction

Indexed keywords

HISTONE METHYLTRANSFERASE; INTERLEUKIN 6; LYSINE; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ARTICLE; CELL ACTIVITY; CHROMATIN IMMUNOPRECIPITATION; DOWN REGULATION; GENE SEQUENCE; HISTONE MODIFICATION; HUMAN; HUMAN CELL; METHYLATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL LINE; HISTONE DEMETHYLASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; INTERLEUKIN-6; LYSINE; METHYLATION; PROMOTER REGIONS, GENETIC; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 78650717706     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016147107     Document Type: Article

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