-
1
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan RA, Dudley ME, Wunderlich JR et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314(5796), 126-129 (2006).
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
-
2
-
-
84925834019
-
-
Gene therapy clinical trials worldwide
-
Gene therapy clinical trials worldwide. www.wiley.co.uk/genmed/clinical
-
-
-
-
3
-
-
0030563195
-
Adenoviruses as gene-delivery vehicles
-
Wilson JM. Adenoviruses as gene-delivery vehicles. N. Engl. J. Med. 334, 1185-1187 (1996)
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1185-1187
-
-
Wilson, J.M.1
-
4
-
-
84880584473
-
High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration
-
Janovitz T, Klein IA, Oliveira T et al. High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration. J. Virol. 87(15), 8559-8568 (2013).
-
(2013)
J. Virol.
, vol.87
, Issue.15
, pp. 8559-8568
-
-
Janovitz, T.1
Klein, I.A.2
Oliveira, T.3
-
5
-
-
0029849257
-
Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
-
Dong JY, Fan PD, Frizzell RA. Quantitative analysis of the packaging capacity of recombinant adeno-associated virus. Hum. Gene Ther. 7(17), 2101-2112 (1996).
-
(1996)
Hum. Gene Ther.
, vol.7
, Issue.17
, pp. 2101-2112
-
-
Dong, J.Y.1
Fan, P.D.2
Frizzell, R.A.3
-
6
-
-
44649139364
-
HIV-1 accessory proteins-ensuring viral survival in a hostile environment
-
Malim MH, Emerman M. HIV-1 accessory proteins-ensuring viral survival in a hostile environment. Cell Host Microbe 3(6), 388-398 (2008).
-
(2008)
Cell Host Microbe
, vol.3
, Issue.6
, pp. 388-398
-
-
Malim, M.H.1
Emerman, M.2
-
7
-
-
0031832923
-
The molecular basis of HIV capsid assembly
-
Jones IM, Morikawa Y. The molecular basis of HIV capsid assembly. Rev. Med. Virol. 8(2), 87-95 (1998).
-
(1998)
Rev. Med. Virol.
, vol.8
, Issue.2
, pp. 87-95
-
-
Jones, I.M.1
Morikawa, Y.2
-
8
-
-
84876926824
-
LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus
-
Finkelshtein D, Werman A, Novick D, Barak S, Rubinstein M. LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus. Proc. Natl Acad. Sci. USA 110(18), 7306-7311 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, Issue.18
, pp. 7306-7311
-
-
Finkelshtein, D.1
Werman, A.2
Novick, D.3
Barak, S.4
Rubinstein, M.5
-
9
-
-
0034646513
-
HIV-1 genome nuclear import is mediated by a central DNA flap
-
Zennou V, Petit C, Guetard D, Nerhbass U, Montagnier L, Charneau P. HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 101(2), 173-185 (2000).
-
(2000)
Cell
, vol.101
, Issue.2
, pp. 173-185
-
-
Zennou, V.1
Petit, C.2
Guetard, D.3
Nerhbass, U.4
Montagnier, L.5
Charneau, P.6
-
10
-
-
0034122464
-
Progress with retroviral gene vectors
-
Palù G, Parolin C, Takeuchi Y, Pizzato M. Progress with retroviral gene vectors. Rev. Med. Virol. 10(3), 185-202 (2000).
-
(2000)
Rev. Med. Virol.
, vol.10
, Issue.3
, pp. 185-202
-
-
Palù, G.1
Parolin, C.2
Takeuchi, Y.3
Pizzato, M.4
-
11
-
-
0020414647
-
Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene
-
Watanabe S, Temin HM. Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene. Proc. Natl Acad. Sci. USA 79(19), 5986-5990 (1982).
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, Issue.19
, pp. 5986-5990
-
-
Watanabe, S.1
Temin, H.M.2
-
12
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull T, Zufferey R, Kelly M et al. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 72(11), 8463-8471 (1998).
-
(1998)
J. Virol.
, vol.72
, Issue.11
, pp. 8463-8471
-
-
Dull, T.1
Zufferey, R.2
Kelly, M.3
-
13
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat. Biotechnol. 15(9), 871-875 (1997).
-
(1997)
Nat. Biotechnol.
, vol.15
, Issue.9
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
Naldini, L.4
Trono, D.5
-
14
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R, Dull T, Mandel RJ et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72(12), 9873-9880 (1998).
-
(1998)
J. Virol.
, vol.72
, Issue.12
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
-
15
-
-
0031666744
-
Development of a self-inactivating lentivirus vector
-
Miyoshi H, Blömer U, Takahashi M, Gage FH, Verma IM. Development of a self-inactivating lentivirus vector. J. Virol. 72(10), 8150-8157 (1998).
-
(1998)
J. Virol.
, vol.72
, Issue.10
, pp. 8150-8157
-
-
Miyoshi, H.1
Blömer, U.2
Takahashi, M.3
Gage, F.H.4
Verma, I.M.5
-
16
-
-
0034672356
-
The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells
-
Sirven A, Pflumio F, Zennou V et al. The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells. Blood 96(13), 4103-4110 (2000).
-
(2000)
Blood
, vol.96
, Issue.13
, pp. 4103-4110
-
-
Sirven, A.1
Pflumio, F.2
Zennou, V.3
-
17
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey R, Donello JE, Trono D, Hope TJ. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 73(4), 2886-2892 (1999).
-
(1999)
J. Virol.
, vol.73
, Issue.4
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
-
18
-
-
0034919136
-
Lentivirus vectors encoding both central polypurine tract and posttranscriptional regulatory element provide enhanced transduction and transgene expression
-
Barry SC, Harder B, Brzezinski M, Flint LY, Seppen J, Osborne WR. Lentivirus vectors encoding both central polypurine tract and posttranscriptional regulatory element provide enhanced transduction and transgene expression. Hum. Gene Ther. 12(9), 1103-1108 (2001).
-
(2001)
Hum. Gene Ther.
, vol.12
, Issue.9
, pp. 1103-1108
-
-
Barry, S.C.1
Harder, B.2
Brzezinski, M.3
Flint, L.Y.4
Seppen, J.5
Osborne, W.R.6
-
19
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen M, Freundlieb S, Bender G, Müller G, Hillen W, Bujard H. Transcriptional activation by tetracyclines in mammalian cells. Science 268(5218), 1766-1769 (1995).
-
(1995)
Science
, vol.268
, Issue.5218
, pp. 1766-1769
-
-
Gossen, M.1
Freundlieb, S.2
Bender, G.3
Müller, G.4
Hillen, W.5
Bujard, H.6
-
20
-
-
0034724857
-
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
-
Cavazzana-Calvo M, Hacein-Bey S, de Saint Basile G et al. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 288(5466), 669-672 (2000).
-
(2000)
Science
, vol.288
, Issue.5466
, pp. 669-672
-
-
Cavazzana-Calvo, M.1
Hacein-Bey, S.2
De Saint Basile, G.3
-
21
-
-
34547657665
-
Hot spots of retroviral integration in human CD34+ hematopoietic cells
-
Cattoglio C, Facchini G, Sartori D et al. Hot spots of retroviral integration in human CD34+ hematopoietic cells. Blood 110(6), 1770-1778 (2007).
-
(2007)
Blood
, vol.110
, Issue.6
, pp. 1770-1778
-
-
Cattoglio, C.1
Facchini, G.2
Sartori, D.3
-
22
-
-
79959935594
-
Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat -thalassemia
-
Ronen K, Negre O, Roth S et al. Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat -thalassemia. Mol. Ther. 19(7), 1273-1286 (2011).
-
(2011)
Mol. Ther.
, vol.19
, Issue.7
, pp. 1273-1286
-
-
Ronen, K.1
Negre, O.2
Roth, S.3
-
23
-
-
84879607520
-
Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents
-
Rittelmeyer I, Rothe M, Brugman MH et al. Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents. Hepatology 58(1), 397-408 (2013).
-
(2013)
Hepatology
, vol.58
, Issue.1
, pp. 397-408
-
-
Rittelmeyer, I.1
Rothe, M.2
Brugman, M.H.3
-
24
-
-
33845187432
-
Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo
-
Philippe S, Sarkis C, Barkats M et al. Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo. Proc. Natl Acad. Sci. USA 103(47), 17684-17689 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.47
, pp. 17684-17689
-
-
Philippe, S.1
Sarkis, C.2
Barkats, M.3
-
25
-
-
33644822908
-
Effective gene therapy with nonintegrating lentiviral vectors
-
Yáñez-Muñoz RJ, Balaggan KS, MacNeil A et al. Effective gene therapy with nonintegrating lentiviral vectors. Nat. Med. 12(3), 348-353 (2006).
-
(2006)
Nat. Med.
, vol.12
, Issue.3
, pp. 348-353
-
-
Yáñez-Muñoz, R.J.1
Balaggan, K.S.2
Macneil, A.3
-
26
-
-
56749185598
-
A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector
-
Bayer M, Kantor B, Cockrell A et al. A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector. Mol. Ther. 16(12), 1968-1976 (2008).
-
(2008)
Mol. Ther.
, vol.16
, Issue.12
, pp. 1968-1976
-
-
Bayer, M.1
Kantor, B.2
Cockrell, A.3
-
27
-
-
36349019180
-
Targeted genome modifications using integrase-deficient lentiviral vectors
-
Cornu TI, Cathomen T. Targeted genome modifications using integrase-deficient lentiviral vectors. Mol. Ther. 15(12), 2107-2113 (2007).
-
(2007)
Mol. Ther.
, vol.15
, Issue.12
, pp. 2107-2113
-
-
Cornu, T.I.1
Cathomen, T.2
-
28
-
-
84875157258
-
A library of TAL effector nucleases spanning the human genome
-
Kim Y, Kweon J, Kim A et al. A library of TAL effector nucleases spanning the human genome. Nat. Biotechnol. 31(3), 251-258 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, Issue.3
, pp. 251-258
-
-
Kim, Y.1
Kweon, J.2
Kim, A.3
-
29
-
-
63149089286
-
Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy
-
Karwacz K, Mukherjee S, Apolonia L et al. Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy. J. Virol. 83(7), 3094-3103 (2009).
-
(2009)
J. Virol.
, vol.83
, Issue.7
, pp. 3094-3103
-
-
Karwacz, K.1
Mukherjee, S.2
Apolonia, L.3
-
30
-
-
84860681545
-
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
-
Provasi E, Genovese P, Lombardo A et al. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer. Nat. Med. 18(5), 807-815 (2012).
-
(2012)
Nat. Med.
, vol.18
, Issue.5
, pp. 807-815
-
-
Provasi, E.1
Genovese, P.2
Lombardo, A.3
-
31
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337(6096), 816-821 (2012).
-
(2012)
Science
, vol.337
, Issue.6096
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
32
-
-
84898665052
-
Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
-
Koike-Yusa H, Li Y, Tan EP, Velasco-Herrera Mdel C, Yusa K. Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library. Nat. Biotechnol. 32(3), 267-273 (2014).
-
(2014)
Nat. Biotechnol.
, vol.32
, Issue.3
, pp. 267-273
-
-
Koike-Yusa, H.1
Li, Y.2
Tan, E.P.3
Velasco-Herrera Mdel, C.4
Yusa, K.5
-
33
-
-
84880571335
-
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
-
Gilbert LA, Larson MH, Morsut L et al. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell 154(2), 442-451 (2013).
-
(2013)
Cell
, vol.154
, Issue.2
, pp. 442-451
-
-
Gilbert, L.A.1
Larson, M.H.2
Morsut, L.3
-
34
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
-
Fu Y, Foden JA, Khayter C et al. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. 9, 822-826 (2013).
-
(2013)
Nat. Biotechnol.
, vol.9
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
-
35
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu PD, Scott DA, Weinstein JA et al. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31, 827-832 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
Scott, D.A.2
Weinstein, J.A.3
-
36
-
-
84884155038
-
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
-
Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol. 31, 839-843 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 839-843
-
-
Pattanayak, V.1
Lin, S.2
Guilinger, J.P.3
Ma, E.4
Doudna, J.A.5
Liu, D.R.6
-
37
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L, Ran FA, Cox D et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
-
38
-
-
84861990434
-
Precision genome engineering with programmable DNA-nicking enzymes
-
Kim E, Kim S, Kim DH, Choi BS, Choi IY, Kim JS. Precision genome engineering with programmable DNA-nicking enzymes. Genome Res. 22(7), 1327-1333 (2012).
-
(2012)
Genome Res.
, vol.22
, Issue.7
, pp. 1327-1333
-
-
Kim, E.1
Kim, S.2
Kim, D.H.3
Choi, B.S.4
Choi, I.Y.5
Kim, J.S.6
-
39
-
-
84861984839
-
Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme
-
Wang J, Friedman G, Doyon Y et al. Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme. Genome Res. 22(7), 1316-1326 (2012).
-
(2012)
Genome Res.
, vol.22
, Issue.7
, pp. 1316-1326
-
-
Wang, J.1
Friedman, G.2
Doyon, Y.3
-
40
-
-
84861960685
-
Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects
-
Ramirez CL, Certo MT, Mussolino C et al. Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects. Nucleic Acids Res. 40(12), 5560-5568 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, Issue.12
, pp. 5560-5568
-
-
Ramirez, C.L.1
Certo, M.T.2
Mussolino, C.3
-
41
-
-
84876389220
-
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells
-
Holkers M, Maggio I, Liu J et al. Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells. Nucleic Acids Res. 41(5), e63 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, Issue.5
, pp. e63
-
-
Holkers, M.1
Maggio, I.2
Liu, J.3
-
42
-
-
0029883624
-
Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy
-
Black ME, Newcomb TG, Wilson HM, Loeb LA. Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy. Proc. Natl Acad. Sci. USA 93(8), 3525-3529 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, Issue.8
, pp. 3525-3529
-
-
Black, M.E.1
Newcomb, T.G.2
Wilson, H.M.3
Loeb, L.A.4
-
43
-
-
84862889768
-
Suicide gene therapy to increase the safety of chimeric antigen receptor-redirected T lymphocytes
-
Casucci M, Bondanza A. Suicide gene therapy to increase the safety of chimeric antigen receptor-redirected T lymphocytes. J. Cancer 2, 378-382 (2001).
-
(2001)
J. Cancer
, vol.2
, pp. 378-382
-
-
Casucci, M.1
Bondanza, A.2
-
44
-
-
33644750264
-
Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation
-
Berger C, Flowers ME, Warren EH, Riddell SR. Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation. Blood 107(6), 2294-2302 (2006).
-
(2006)
Blood
, vol.107
, Issue.6
, pp. 2294-2302
-
-
Berger, C.1
Flowers, M.E.2
Warren, E.H.3
Riddell, S.R.4
-
45
-
-
34247194881
-
Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy
-
Sato T, Neschadim A, Konrad AM, Fowler DH, Lavie A, Medin JA. Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. Mol. Ther. 15(5), 962-970 (2007).
-
(2007)
Mol. Ther.
, vol.15
, Issue.5
, pp. 962-970
-
-
Sato, T.1
Neschadim, A.2
Konrad, A.M.3
Fowler, D.H.4
Lavie, A.5
Medin, J.A.6
-
46
-
-
84862829497
-
Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase
-
Neschadim A, Wang JC, Sato T, Fowler DH, Lavie A, Medin JA. Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase. Mol. Ther. 20(5), 1002-1013 (2012).
-
(2012)
Mol. Ther.
, vol.20
, Issue.5
, pp. 1002-1013
-
-
Neschadim, A.1
Wang, J.C.2
Sato, T.3
Fowler, D.H.4
Lavie, A.5
Medin, J.A.6
-
47
-
-
84871978590
-
Engineered human Tmpk fused with truncated cell-surface markers: Versatile cell-fate control safety cassettes
-
Scaife M, Pacienza N, Au BC et al. Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes. Gene Ther. 20(1), 24-34 (2013).
-
(2013)
Gene Ther.
, vol.20
, Issue.1
, pp. 24-34
-
-
Scaife, M.1
Pacienza, N.2
Au, B.C.3
-
48
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 392(6673), 245-252 (1998).
-
(1998)
Nature
, vol.392
, Issue.6673
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
49
-
-
0031941423
-
Vaccination of melanoma patients with peptide or tumor lysate-pulsed dendritic cells
-
Nestle FO, Alijagic S, Gilliet M et al. Vaccination of melanoma patients with peptide or tumor lysate-pulsed dendritic cells. Nat. Med. 4(3), 328-332 (1998).
-
(1998)
Nat. Med.
, vol.4
, Issue.3
, pp. 328-332
-
-
Nestle, F.O.1
Alijagic, S.2
Gilliet, M.3
-
50
-
-
84898746976
-
Sipuleucel-T and immunotherapy in the treatment of prostate cancer
-
Dawson NA, Roesch EE. Sipuleucel-T and immunotherapy in the treatment of prostate cancer. Expert Opin. Biol. Ther. 14(5), 709-719 (2014).
-
(2014)
Expert Opin. Biol. Ther.
, vol.14
, Issue.5
, pp. 709-719
-
-
Dawson, N.A.1
Roesch, E.E.2
-
51
-
-
0842312143
-
Lentivirally transduced dendritic cells as a tool for cancer immunotherapy
-
Breckpot K, Dullaers M, Bonehill A et al. Lentivirally transduced dendritic cells as a tool for cancer immunotherapy. J. Gene Med. 5(8), 654-667 (2003).
-
(2003)
J. Gene Med.
, vol.5
, Issue.8
, pp. 654-667
-
-
Breckpot, K.1
Dullaers, M.2
Bonehill, A.3
-
52
-
-
4143137360
-
Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction
-
Jeon, MS, Atfield, A., Venuprasad, K et al. Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction. Immunity 21(2), 167-177 (2004).
-
(2004)
Immunity
, vol.21
, Issue.2
, pp. 167-177
-
-
Jeon, S.M.1
Atfield, A.2
Venuprasad, K.3
-
53
-
-
33745736420
-
T-cell tolerance or function is determined by combinatorial costimulatory signals
-
Nurieva, R., Thomas, S., Nguyen, T et al. T-cell tolerance or function is determined by combinatorial costimulatory signals. EMBO J. 25(11), 2623-2633 (2006).
-
(2006)
EMBO J.
, vol.25
, Issue.11
, pp. 2623-2633
-
-
Nurieva, R.1
Thomas, S.2
Nguyen, T.3
-
54
-
-
0242579946
-
CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine
-
Curtsinger, JM, Johnson, CM, Mescher, MF. CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine. J. Immunol. 171(10), 5165-5171 (2003).
-
(2003)
J. Immunol.
, vol.171
, Issue.10
, pp. 5165-5171
-
-
Curtsinger, M.J.1
Johnson, M.C.2
Mescher, F.M.3
-
55
-
-
80053927917
-
PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8(+) T cells
-
Karwacz, K, Bricogne, C, MacDonald, D et al. PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8(+) T cells. EMBO Mol. Med. 3(10), 581-592 (2011).
-
(2011)
EMBO Mol. Med.
, vol.3
, Issue.10
, pp. 581-592
-
-
Karwacz, K.1
Bricogne, C.2
Macdonald, D.3
-
56
-
-
84908031412
-
Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells
-
2014
-
Pen, JJ, Keersmaecker, BD, Heirman, C et al. (2014). Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells. Gene Ther. 21(3), 262-271 (2014).
-
(2014)
Gene Ther.
, vol.21
, Issue.3
, pp. 262-271
-
-
Pen, J.J.1
Keersmaecker, D.B.2
Heirman, C.3
-
57
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife, BT, Pauken, KE, Eagar, TN et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat. Immunol. 10(11), U1185-U1170 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, Issue.11
, pp. U1185-U1170
-
-
Fife, T.B.1
Pauken, E.K.2
Eagar, N.T.3
-
58
-
-
42449157639
-
Targeting dendritic cell signaling to regulate the response to immunization
-
Escors, D, Lopes, L, Lin, R et al. Targeting dendritic cell signaling to regulate the response to immunization. Blood 111(6), 3050-3061 (2008).
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3050-3061
-
-
Escors, D.1
Lopes, L.2
Lin, R.3
-
59
-
-
80054088221
-
Differential immune responses mediated by adenovirus-and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model
-
Felizardo TC, Wang JCM, Mcgray RA et al. Differential immune responses mediated by adenovirus-and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model. Gene Ther. 18(10), 986-995 (2011).
-
(2011)
Gene Ther.
, vol.18
, Issue.10
, pp. 986-995
-
-
Felizardo, T.C.1
Wang, J.C.M.2
McGray, R.A.3
-
60
-
-
33947583453
-
In vivo administration of lentiviral vectors triggers a type i interferon response that restricts hepatocyte gene transfer and promotes vector clearance
-
Brown BD, Sitia G, Annoni A et al. In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance. Blood 109(7), 2797-2805 (2007).
-
(2007)
Blood
, vol.109
, Issue.7
, pp. 2797-2805
-
-
Brown, B.D.1
Sitia, G.2
Annoni, A.3
-
61
-
-
77951993592
-
HIV-1 lentiviral vector immunogenicity is mediated by Toll-Like Receptor 3 (TLR3) and TLR7
-
Breckpot K, Escors D, Arce F et al. HIV-1 lentiviral vector immunogenicity is mediated by Toll-Like Receptor 3 (TLR3) and TLR7. J. Virol. 84(11), 5627-5636 (2010).
-
(2010)
J. Virol.
, vol.84
, Issue.11
, pp. 5627-5636
-
-
Breckpot, K.1
Escors, D.2
Arce, F.3
-
62
-
-
0035695838
-
Lentiviral vector-mediated tyrosinase-related protein 2 gene transfer to dendritic cells for the therapy of melanoma
-
Metharom P, Ellem KA, Schmidt C, Wei MQ. Lentiviral vector-mediated tyrosinase-related protein 2 gene transfer to dendritic cells for the therapy of melanoma. Hum. Gene Ther. 12(18), 2203-2213 (2001).
-
(2001)
Hum. Gene Ther.
, vol.12
, Issue.18
, pp. 2203-2213
-
-
Metharom, P.1
Ellem, K.A.2
Schmidt, C.3
Wei, M.Q.4
-
63
-
-
33846062266
-
Gene transfer to dendritic cells induced a protective immunity against melanoma
-
Metharom P, Ellem KA, Wei MQ. Gene transfer to dendritic cells induced a protective immunity against melanoma. Cell Mol. Immunol. 2(4), 281-288 (2005).
-
(2005)
Cell Mol. Immunol.
, vol.2
, Issue.4
, pp. 281-288
-
-
Metharom, P.1
Ellem, K.A.2
Wei, M.Q.3
-
64
-
-
34247189774
-
Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines
-
Koya RC, Kimura T, Ribas A et al. Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines. Mol. Ther. 15(5), 971-980 (2007).
-
(2007)
Mol. Ther.
, vol.15
, Issue.5
, pp. 971-980
-
-
Koya, R.C.1
Kimura, T.2
Ribas, A.3
-
65
-
-
33645229133
-
An effective cancer vaccine modality: Lentiviral modification of dendritic cells expressing multiple cancer-specific antigens
-
Wang B, He J, Liu C, Chang LJ. An effective cancer vaccine modality: Lentiviral modification of dendritic cells expressing multiple cancer-specific antigens. Vaccine 24(17), 3477-3489 (2006).
-
(2006)
Vaccine
, vol.24
, Issue.17
, pp. 3477-3489
-
-
Wang, B.1
He, J.2
Liu, C.3
Chang, L.J.4
-
66
-
-
39849098133
-
Tumor protection following vaccination with low doses of lentivirally transduced DCs expressing the self-antigen erbB2
-
Mossoba ME, Walia JS, Rasaiah VI et al. Tumor protection following vaccination with low doses of lentivirally transduced DCs expressing the self-antigen erbB2. Mol. Ther. 16(3), 607-617 (2008).
-
(2008)
Mol. Ther.
, vol.16
, Issue.3
, pp. 607-617
-
-
Mossoba, M.E.1
Walia, J.S.2
Rasaiah, V.I.3
-
67
-
-
84876447672
-
Dendritic cell directed vaccination with a lentivector encoding PSCA for prostate cancer in mice
-
Xiao L, Joo K-I, Lim M, Wang P. Dendritic cell directed vaccination with a lentivector encoding PSCA for prostate cancer in mice. PLoS ONE 7(11) e48866, (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.11
, pp. e48866
-
-
Xiao, L.1
Joo, K.-I.2
Lim, M.3
Wang, P.4
-
68
-
-
0028285230
-
Proliferating dendritic cell progenitors in human blood
-
Romani N, Gruner S, Brang D et al. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180(1), 83-93 (1994).
-
(1994)
J. Exp. Med.
, vol.180
, Issue.1
, pp. 83-93
-
-
Romani, N.1
Gruner, S.2
Brang, D.3
-
69
-
-
0028289244
-
Efficient presentation of soluble-antigen by cultured human dendritic cells is maintained by granulocyte-macrophage colony-stimulating factor plus interleukin-4 and down-regulated by Tumor-Necrosis-Factor-alpha
-
Sallusto F, Lanzavecchia A. Efficient presentation of soluble-antigen by cultured human dendritic cells is maintained by granulocyte-macrophage colony-stimulating factor plus interleukin-4 and down-regulated by Tumor-Necrosis-Factor-alpha. J. Exp. Med. 179(4), 1109-1118 (1994).
-
(1994)
J. Exp. Med.
, vol.179
, Issue.4
, pp. 1109-1118
-
-
Sallusto, F.1
Lanzavecchia, A.2
-
70
-
-
0026702360
-
Interactions of tumor-necrosis-factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell-growth in vitro from early bipotent CD34+ progenitors in human bone-marrow
-
Reid CDL, Stackpoole A, Meager A, Tikerpae J. Interactions of tumor-necrosis-factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell-growth in vitro from early bipotent CD34+ progenitors in human bone-marrow. J. Immunol. 149(8), 2681-2688 (1992).
-
(1992)
J. Immunol.
, vol.149
, Issue.8
, pp. 2681-2688
-
-
Reid, C.D.L.1
Stackpoole, A.2
Meager, A.3
Tikerpae, J.4
-
71
-
-
0035404586
-
Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells
-
Salmon P, Arrighi JF, Piguet V et al. Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells. J. Gene Med. 3(4), 311-320 (2001).
-
(2001)
J. Gene Med.
, vol.3
, Issue.4
, pp. 311-320
-
-
Salmon, P.1
Arrighi, J.F.2
Piguet, V.3
-
72
-
-
0034283912
-
Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors
-
Chinnasamy N, Chinnasamy D, Toso JF et al. Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors. Hum. Gene Ther. 11(13), 1901-1909 (2000).
-
(2000)
Hum. Gene Ther.
, vol.11
, Issue.13
, pp. 1901-1909
-
-
Chinnasamy, N.1
Chinnasamy, D.2
Toso, J.F.3
-
73
-
-
80052599019
-
Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy
-
Senju S, Haruta M, Matsumura K et al. Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy. Gene Ther. 18(9), 874-883 (2011).
-
(2011)
Gene Ther.
, vol.18
, Issue.9
, pp. 874-883
-
-
Senju, S.1
Haruta, M.2
Matsumura, K.3
-
74
-
-
3042749373
-
Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro
-
Zhan XC, Dravid G, Ye ZH et al. Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet 364(9429), 163-171 (2004).
-
(2004)
Lancet
, vol.364
, Issue.9429
, pp. 163-171
-
-
Zhan, X.C.1
Dravid, G.2
Ye, Z.H.3
-
75
-
-
0036721329
-
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
-
Kamath AT, Henri S, Battye F, Tough DF, Shortman K. Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood 100(5), 1734-1741 (2002).
-
(2002)
Blood
, vol.100
, Issue.5
, pp. 1734-1741
-
-
Kamath, A.T.1
Henri, S.2
Battye, F.3
Tough, D.F.4
Shortman, K.5
-
76
-
-
84880334859
-
Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways
-
Wang JCM, Felizardo TC, Au BCY, Fowler DH, Dekaban GA, Medin JA. Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways. Virol. J. 10, 240 (2013).
-
(2013)
Virol. J.
, vol.10
, pp. 240
-
-
Wang, J.C.M.1
Felizardo, T.C.2
Au, B.C.Y.3
Fowler, D.H.4
Dekaban, G.A.5
Medin, J.A.6
-
77
-
-
33745609027
-
Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization
-
He YK, Zhang JY, Donahue C, Falo LD. Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization. Immunity 24(5), 643-656 (2006).
-
(2006)
Immunity
, vol.24
, Issue.5
, pp. 643-656
-
-
He, Y.K.1
Zhang, J.Y.2
Donahue, C.3
Falo, L.D.4
-
78
-
-
34548108611
-
Successful immunization with a single injection of non-integrating lentiviral vector
-
Negri DRM, Michelini Z, Baroncelli S et al. Successful immunization with a single injection of non-integrating lentiviral vector. Mol. Ther. 15(9), 1716-1723 (2007).
-
(2007)
Mol. Ther.
, vol.15
, Issue.9
, pp. 1716-1723
-
-
Negri, D.R.M.1
Michelini, Z.2
Baroncelli, S.3
-
79
-
-
73949111672
-
HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells
-
Dai B, Yang L, Yang H, Hu B, Baltimore D, Wang P. HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells. Proc. Natl Acad. Sci. USA 106(48), 20382-20387 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.48
, pp. 20382-20387
-
-
Dai, B.1
Yang, L.2
Yang, H.3
Hu, B.4
Baltimore, D.5
Wang, P.6
-
80
-
-
9344269897
-
Expression of costimulatory molecules in human leukemias
-
Hirano N, Takahashi T, Ohtake S et al. Expression of costimulatory molecules in human leukemias. Leukemia 10(7), 1168-1176 (1996).
-
(1996)
Leukemia
, vol.10
, Issue.7
, pp. 1168-1176
-
-
Hirano, N.1
Takahashi, T.2
Ohtake, S.3
-
81
-
-
0027239503
-
Anti-tumor and anti-metastatic activity of interleukin-12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR et al. Anti-tumor and anti-metastatic activity of interleukin-12 against murine tumors. J. Exp. Med. 178(4), 1223-1230 (1993).
-
(1993)
J. Exp. Med.
, vol.178
, Issue.4
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
-
82
-
-
0028824039
-
IL-12 deaths: Explanation and a puzzle
-
Cohen J. IL-12 deaths: explanation and a puzzle. Science 270(5238), 908-908 (1995).
-
(1995)
Science
, vol.270
, Issue.5238
, pp. 908-908
-
-
Cohen, J.1
-
83
-
-
0034103809
-
Phase i trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: Ability to maintain IFN-gamma induction is associated with clinical response
-
Gollob JA, Mier JW, Veenstra K et al. Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: Ability to maintain IFN-gamma induction is associated with clinical response. Clin. Cancer Res. 6(5), 1678-1692 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, Issue.5
, pp. 1678-1692
-
-
Gollob, J.A.1
Mier, J.W.2
Veenstra, K.3
-
84
-
-
0033973093
-
Cytokines and soluble cytokine receptor induction after IL-12 administration in cancer patients
-
Haicheur N, Escudier B, Dorval T et al. Cytokines and soluble cytokine receptor induction after IL-12 administration in cancer patients. Clin. Exp. Immunol. 119(1), 28-37 (2000).
-
(2000)
Clin. Exp. Immunol.
, vol.119
, Issue.1
, pp. 28-37
-
-
Haicheur, N.1
Escudier, B.2
Dorval, T.3
-
85
-
-
0037242365
-
Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses
-
Portielje JEA, Lamers CHJ, Kruit WHJ et al. Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses. Clin. Cancer Res. 9(1), 76-83 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.1
, pp. 76-83
-
-
Portielje, J.E.A.1
Lamers, C.H.J.2
Kruit, W.H.J.3
-
86
-
-
0031564332
-
Enhanced immunogenicity of B cell lymphoma genetically engineered to express both B7-1 and interleukin-12
-
Pizzoferrato E, Chu NR, Hawley TS et al. Enhanced immunogenicity of B cell lymphoma genetically engineered to express both B7-1 and interleukin-12. Hum. Gene Ther. 8(18), 2217-2228 (1997).
-
(1997)
Hum. Gene Ther.
, vol.8
, Issue.18
, pp. 2217-2228
-
-
Pizzoferrato, E.1
Chu, N.R.2
Hawley, T.S.3
-
87
-
-
72949086895
-
IL-12 immunotherapy of murine leukaemia: Comparison of systemic versus gene modified cell therapy
-
Labbe A, Nelles M, Walia J et al. IL-12 immunotherapy of murine leukaemia: comparison of systemic versus gene modified cell therapy. J. Cell Mol. Med. 13(8B), 1962-1976 (2009).
-
(2009)
J. Cell Mol. Med.
, vol.13
, Issue.8 B
, pp. 1962-1976
-
-
Labbe, A.1
Nelles, M.2
Walia, J.3
-
88
-
-
84891148986
-
Localized interleukin-12 delivery for immunotherapy of solid tumours
-
Wei LZ, Xu Y, Nelles ME et al. Localized interleukin-12 delivery for immunotherapy of solid tumours. J. Cell Mol. Med. 17(11), 1465-1474 (2013).
-
(2013)
J. Cell Mol. Med.
, vol.17
, Issue.11
, pp. 1465-1474
-
-
Wei, L.Z.1
Xu, Y.2
Nelles, M.E.3
-
89
-
-
0034663189
-
Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage-colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce anti-leukemic immune responses
-
Stripecke R, Cardoso AA, Pepper KA et al. Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage-colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce anti-leukemic immune responses. Blood 96(4), 1317-1326 (2000).
-
(2000)
Blood
, vol.96
, Issue.4
, pp. 1317-1326
-
-
Stripecke, R.1
Cardoso, A.A.2
Pepper, K.A.3
-
90
-
-
10944238100
-
IL-2/B7. 1 (CD80) fusagene transduction of AML blasts by a self-inactivating lentiviral vector stimulates T cell responses in vitro: A strategy to generate whole cell vaccines for AML
-
Chan L, Hardwick N, Darling D et al. IL-2/B7.1 (CD80) fusagene transduction of AML blasts by a self-inactivating lentiviral vector stimulates T cell responses in vitro: a strategy to generate whole cell vaccines for AML. Mol. Ther. 11(1), 120-131 (2005).
-
(2005)
Mol. Ther.
, vol.11
, Issue.1
, pp. 120-131
-
-
Chan, L.1
Hardwick, N.2
Darling, D.3
-
91
-
-
0033120418
-
A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission
-
Cortes JE, Kantarjian HM, O'Brien S et al. A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission. Cancer 85(7), 1506-1513 (1999).
-
(1999)
Cancer
, vol.85
, Issue.7
, pp. 1506-1513
-
-
Cortes, J.E.1
Kantarjian, H.M.2
O'brien, S.3
-
92
-
-
34247212403
-
Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules
-
Suhoski MM, Golovina TN, Aqui NA et al. Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules. Mol. Ther. 15(5), 981-988 (2007).
-
(2007)
Mol. Ther.
, vol.15
, Issue.5
, pp. 981-988
-
-
Suhoski, M.M.1
Golovina, T.N.2
Aqui, N.A.3
-
93
-
-
0022538117
-
Transfer of specificity by murine alpha-T-cell and beta-T-cell receptor genes
-
Dembic Z, Haas W, Weiss S et al. Transfer of specificity by murine alpha-T-cell and beta-T-cell receptor genes. Nature 320(6059), 232-238 (1986).
-
(1986)
Nature
, vol.320
, Issue.6059
, pp. 232-238
-
-
Dembic, Z.1
Haas, W.2
Weiss, S.3
-
94
-
-
54549106702
-
Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition
-
Yang S, Cohen CJ, Peng PD et al. Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition. Gene Ther. 15(21), 1411-1423 (2008).
-
(2008)
Gene Ther.
, vol.15
, Issue.21
, pp. 1411-1423
-
-
Yang, S.1
Cohen, C.J.2
Peng, P.D.3
-
95
-
-
84925727210
-
-
Clinicaltrials.gov NCT01795976
-
Clinicaltrials.gov NCT01795976. https://clinicaltrials.gov/ct2/show/NCT01795976
-
-
-
-
96
-
-
84925764677
-
-
Clinicaltrials.gov NCT00910650
-
Clinicaltrials.gov NCT00910650. https://clinicaltrials.gov/ct2/show/NCT00910650
-
-
-
-
97
-
-
77952236875
-
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
-
Bendle GM, Linnemann C, Hooijkaas AI et al. Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat. Med. 16(5), 565-570 (2010).
-
(2010)
Nat. Med.
, vol.16
, Issue.5
, pp. 565-570
-
-
Bendle, G.M.1
Linnemann, C.2
Hooijkaas, A.I.3
-
98
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N. Engl. J. Med. 365(8), 725-733 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, Issue.8
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
99
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
Kochenderfer JN, Dudley ME, Feldman SA et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119(12), 2709-2720 (2012).
-
(2012)
Blood
, vol.119
, Issue.12
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
-
100
-
-
0347994955
-
Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain
-
Finney HM, Akbar AN, Lawson ADG. Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain. J. Immunol. 172(1), 104-113 (2004).
-
(2004)
J. Immunol.
, vol.172
, Issue.1
, pp. 104-113
-
-
Finney, H.M.1
Akbar, A.N.2
Lawson, A.D.G.3
-
101
-
-
3042551216
-
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
-
Imai C, Mihara K, Andreansky M et al. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia 18(4), 676-684 (2004).
-
(2004)
Leukemia
, vol.18
, Issue.4
, pp. 676-684
-
-
Imai, C.1
Mihara, K.2
Andreansky, M.3
-
102
-
-
0027471898
-
Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma-subunit or zeta-subunit of the immunoglobulin and T-cell receptors
-
Eshhar Z, Waks T, Gross G, Schindler DG. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma-subunit or zeta-subunit of the immunoglobulin and T-cell receptors. Proc. Natl Acad. Sci. USA 90(2), 720-724 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, Issue.2
, pp. 720-724
-
-
Eshhar, Z.1
Waks, T.2
Gross, G.3
Schindler, D.G.4
-
103
-
-
84902582355
-
Retargeting NK-92 cells by means of CD19-and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity
-
Boissel L, Betancur-Boissel M, Lu W et al. Retargeting NK-92 cells by means of CD19-and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity. Oncoimmunology 2(10), e26527 (2013).
-
(2013)
Oncoimmunology
, vol.2
, Issue.10
, pp. e26527
-
-
Boissel, L.1
Betancur-Boissel, M.2
Lu, W.3
-
104
-
-
84455172814
-
Predicting cytokine storms: It's about density
-
Frigault MJ, June CH. Predicting cytokine storms: it's about density. Blood 118(26), 6724-6726 (2011).
-
(2011)
Blood
, vol.118
, Issue.26
, pp. 6724-6726
-
-
Frigault, M.J.1
June, C.H.2
-
105
-
-
80455162464
-
Inducible apoptosis as a safety switch for adoptive cell therapy
-
Di Stasi A, Tey S-K, Dotti G et al. Inducible apoptosis as a safety switch for adoptive cell therapy. N. Engl. J. Med. 365(18), 1673-1683 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, Issue.18
, pp. 1673-1683
-
-
Di Stasi, A.1
Tey, S.-K.2
Dotti, G.3
-
106
-
-
83455213653
-
Treatment of advanced leukemia in mice with mRNA engineered T cells
-
Barrett DM, Zhao Y, Liu X et al. Treatment of advanced leukemia in mice with mRNA engineered T cells. Hum. Gene Ther. 22(12), 1575-1586 (2011).
-
(2011)
Hum. Gene Ther.
, vol.22
, Issue.12
, pp. 1575-1586
-
-
Barrett, D.M.1
Zhao, Y.2
Liu, X.3
-
107
-
-
84890207337
-
T cells expressing chimeric antigen receptors can cause anaphylaxis in humans
-
Maus MV, Haas AR, Beatty GL et al. T cells expressing chimeric antigen receptors can cause anaphylaxis in humans. Cancer Immunol. Res. 1(1), 26-31 (2013).
-
(2013)
Cancer Immunol. Res.
, vol.1
, Issue.1
, pp. 26-31
-
-
Maus, M.V.1
Haas, A.R.2
Beatty, G.L.3
|