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Volumn 7, Issue 3, 2015, Pages 271-284

Lentiviral vectors in cancer immunotherapy

Author keywords

cancer; cell fate control system; cellular immunity; chimeric antigen receptor; cytokines; dendritic cells; immunotherapy; lentivirus; T cells; transgene

Indexed keywords

CANCER VACCINE; CHIMERIC ANTIGEN RECEPTOR; DENDRITIC CELL VACCINE; LENTIVIRUS VECTOR; NUCLEASE; T LYMPHOCYTE RECEPTOR;

EID: 84925805603     PISSN: 1750743X     EISSN: 17507448     Source Type: Journal    
DOI: 10.2217/imt.14.108     Document Type: Review
Times cited : (30)

References (107)
  • 1
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan RA, Dudley ME, Wunderlich JR et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314(5796), 126-129 (2006).
    • (2006) Science , vol.314 , Issue.5796 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3
  • 2
    • 84925834019 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide
    • Gene therapy clinical trials worldwide. www.wiley.co.uk/genmed/clinical
  • 3
    • 0030563195 scopus 로고    scopus 로고
    • Adenoviruses as gene-delivery vehicles
    • Wilson JM. Adenoviruses as gene-delivery vehicles. N. Engl. J. Med. 334, 1185-1187 (1996)
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1185-1187
    • Wilson, J.M.1
  • 4
    • 84880584473 scopus 로고    scopus 로고
    • High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration
    • Janovitz T, Klein IA, Oliveira T et al. High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration. J. Virol. 87(15), 8559-8568 (2013).
    • (2013) J. Virol. , vol.87 , Issue.15 , pp. 8559-8568
    • Janovitz, T.1    Klein, I.A.2    Oliveira, T.3
  • 5
    • 0029849257 scopus 로고    scopus 로고
    • Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
    • Dong JY, Fan PD, Frizzell RA. Quantitative analysis of the packaging capacity of recombinant adeno-associated virus. Hum. Gene Ther. 7(17), 2101-2112 (1996).
    • (1996) Hum. Gene Ther. , vol.7 , Issue.17 , pp. 2101-2112
    • Dong, J.Y.1    Fan, P.D.2    Frizzell, R.A.3
  • 6
    • 44649139364 scopus 로고    scopus 로고
    • HIV-1 accessory proteins-ensuring viral survival in a hostile environment
    • Malim MH, Emerman M. HIV-1 accessory proteins-ensuring viral survival in a hostile environment. Cell Host Microbe 3(6), 388-398 (2008).
    • (2008) Cell Host Microbe , vol.3 , Issue.6 , pp. 388-398
    • Malim, M.H.1    Emerman, M.2
  • 7
    • 0031832923 scopus 로고    scopus 로고
    • The molecular basis of HIV capsid assembly
    • Jones IM, Morikawa Y. The molecular basis of HIV capsid assembly. Rev. Med. Virol. 8(2), 87-95 (1998).
    • (1998) Rev. Med. Virol. , vol.8 , Issue.2 , pp. 87-95
    • Jones, I.M.1    Morikawa, Y.2
  • 8
    • 84876926824 scopus 로고    scopus 로고
    • LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus
    • Finkelshtein D, Werman A, Novick D, Barak S, Rubinstein M. LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus. Proc. Natl Acad. Sci. USA 110(18), 7306-7311 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , Issue.18 , pp. 7306-7311
    • Finkelshtein, D.1    Werman, A.2    Novick, D.3    Barak, S.4    Rubinstein, M.5
  • 11
    • 0020414647 scopus 로고
    • Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene
    • Watanabe S, Temin HM. Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene. Proc. Natl Acad. Sci. USA 79(19), 5986-5990 (1982).
    • (1982) Proc. Natl Acad. Sci. USA , vol.79 , Issue.19 , pp. 5986-5990
    • Watanabe, S.1    Temin, H.M.2
  • 12
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • Dull T, Zufferey R, Kelly M et al. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 72(11), 8463-8471 (1998).
    • (1998) J. Virol. , vol.72 , Issue.11 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3
  • 13
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat. Biotechnol. 15(9), 871-875 (1997).
    • (1997) Nat. Biotechnol. , vol.15 , Issue.9 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5
  • 14
    • 0031743608 scopus 로고    scopus 로고
    • Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
    • Zufferey R, Dull T, Mandel RJ et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72(12), 9873-9880 (1998).
    • (1998) J. Virol. , vol.72 , Issue.12 , pp. 9873-9880
    • Zufferey, R.1    Dull, T.2    Mandel, R.J.3
  • 16
    • 0034672356 scopus 로고    scopus 로고
    • The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells
    • Sirven A, Pflumio F, Zennou V et al. The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells. Blood 96(13), 4103-4110 (2000).
    • (2000) Blood , vol.96 , Issue.13 , pp. 4103-4110
    • Sirven, A.1    Pflumio, F.2    Zennou, V.3
  • 17
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey R, Donello JE, Trono D, Hope TJ. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 73(4), 2886-2892 (1999).
    • (1999) J. Virol. , vol.73 , Issue.4 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3    Hope, T.J.4
  • 18
    • 0034919136 scopus 로고    scopus 로고
    • Lentivirus vectors encoding both central polypurine tract and posttranscriptional regulatory element provide enhanced transduction and transgene expression
    • Barry SC, Harder B, Brzezinski M, Flint LY, Seppen J, Osborne WR. Lentivirus vectors encoding both central polypurine tract and posttranscriptional regulatory element provide enhanced transduction and transgene expression. Hum. Gene Ther. 12(9), 1103-1108 (2001).
    • (2001) Hum. Gene Ther. , vol.12 , Issue.9 , pp. 1103-1108
    • Barry, S.C.1    Harder, B.2    Brzezinski, M.3    Flint, L.Y.4    Seppen, J.5    Osborne, W.R.6
  • 19
    • 0029022369 scopus 로고
    • Transcriptional activation by tetracyclines in mammalian cells
    • Gossen M, Freundlieb S, Bender G, Müller G, Hillen W, Bujard H. Transcriptional activation by tetracyclines in mammalian cells. Science 268(5218), 1766-1769 (1995).
    • (1995) Science , vol.268 , Issue.5218 , pp. 1766-1769
    • Gossen, M.1    Freundlieb, S.2    Bender, G.3    Müller, G.4    Hillen, W.5    Bujard, H.6
  • 20
    • 0034724857 scopus 로고    scopus 로고
    • Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
    • Cavazzana-Calvo M, Hacein-Bey S, de Saint Basile G et al. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 288(5466), 669-672 (2000).
    • (2000) Science , vol.288 , Issue.5466 , pp. 669-672
    • Cavazzana-Calvo, M.1    Hacein-Bey, S.2    De Saint Basile, G.3
  • 21
    • 34547657665 scopus 로고    scopus 로고
    • Hot spots of retroviral integration in human CD34+ hematopoietic cells
    • Cattoglio C, Facchini G, Sartori D et al. Hot spots of retroviral integration in human CD34+ hematopoietic cells. Blood 110(6), 1770-1778 (2007).
    • (2007) Blood , vol.110 , Issue.6 , pp. 1770-1778
    • Cattoglio, C.1    Facchini, G.2    Sartori, D.3
  • 22
    • 79959935594 scopus 로고    scopus 로고
    • Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat -thalassemia
    • Ronen K, Negre O, Roth S et al. Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat -thalassemia. Mol. Ther. 19(7), 1273-1286 (2011).
    • (2011) Mol. Ther. , vol.19 , Issue.7 , pp. 1273-1286
    • Ronen, K.1    Negre, O.2    Roth, S.3
  • 23
    • 84879607520 scopus 로고    scopus 로고
    • Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents
    • Rittelmeyer I, Rothe M, Brugman MH et al. Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents. Hepatology 58(1), 397-408 (2013).
    • (2013) Hepatology , vol.58 , Issue.1 , pp. 397-408
    • Rittelmeyer, I.1    Rothe, M.2    Brugman, M.H.3
  • 24
    • 33845187432 scopus 로고    scopus 로고
    • Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo
    • Philippe S, Sarkis C, Barkats M et al. Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo. Proc. Natl Acad. Sci. USA 103(47), 17684-17689 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.47 , pp. 17684-17689
    • Philippe, S.1    Sarkis, C.2    Barkats, M.3
  • 25
    • 33644822908 scopus 로고    scopus 로고
    • Effective gene therapy with nonintegrating lentiviral vectors
    • Yáñez-Muñoz RJ, Balaggan KS, MacNeil A et al. Effective gene therapy with nonintegrating lentiviral vectors. Nat. Med. 12(3), 348-353 (2006).
    • (2006) Nat. Med. , vol.12 , Issue.3 , pp. 348-353
    • Yáñez-Muñoz, R.J.1    Balaggan, K.S.2    Macneil, A.3
  • 26
    • 56749185598 scopus 로고    scopus 로고
    • A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector
    • Bayer M, Kantor B, Cockrell A et al. A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector. Mol. Ther. 16(12), 1968-1976 (2008).
    • (2008) Mol. Ther. , vol.16 , Issue.12 , pp. 1968-1976
    • Bayer, M.1    Kantor, B.2    Cockrell, A.3
  • 27
    • 36349019180 scopus 로고    scopus 로고
    • Targeted genome modifications using integrase-deficient lentiviral vectors
    • Cornu TI, Cathomen T. Targeted genome modifications using integrase-deficient lentiviral vectors. Mol. Ther. 15(12), 2107-2113 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.12 , pp. 2107-2113
    • Cornu, T.I.1    Cathomen, T.2
  • 28
    • 84875157258 scopus 로고    scopus 로고
    • A library of TAL effector nucleases spanning the human genome
    • Kim Y, Kweon J, Kim A et al. A library of TAL effector nucleases spanning the human genome. Nat. Biotechnol. 31(3), 251-258 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , Issue.3 , pp. 251-258
    • Kim, Y.1    Kweon, J.2    Kim, A.3
  • 29
    • 63149089286 scopus 로고    scopus 로고
    • Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy
    • Karwacz K, Mukherjee S, Apolonia L et al. Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy. J. Virol. 83(7), 3094-3103 (2009).
    • (2009) J. Virol. , vol.83 , Issue.7 , pp. 3094-3103
    • Karwacz, K.1    Mukherjee, S.2    Apolonia, L.3
  • 30
    • 84860681545 scopus 로고    scopus 로고
    • Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
    • Provasi E, Genovese P, Lombardo A et al. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer. Nat. Med. 18(5), 807-815 (2012).
    • (2012) Nat. Med. , vol.18 , Issue.5 , pp. 807-815
    • Provasi, E.1    Genovese, P.2    Lombardo, A.3
  • 31
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337(6096), 816-821 (2012).
    • (2012) Science , vol.337 , Issue.6096 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 32
    • 84898665052 scopus 로고    scopus 로고
    • Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
    • Koike-Yusa H, Li Y, Tan EP, Velasco-Herrera Mdel C, Yusa K. Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library. Nat. Biotechnol. 32(3), 267-273 (2014).
    • (2014) Nat. Biotechnol. , vol.32 , Issue.3 , pp. 267-273
    • Koike-Yusa, H.1    Li, Y.2    Tan, E.P.3    Velasco-Herrera Mdel, C.4    Yusa, K.5
  • 33
    • 84880571335 scopus 로고    scopus 로고
    • CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
    • Gilbert LA, Larson MH, Morsut L et al. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell 154(2), 442-451 (2013).
    • (2013) Cell , vol.154 , Issue.2 , pp. 442-451
    • Gilbert, L.A.1    Larson, M.H.2    Morsut, L.3
  • 34
    • 84880570576 scopus 로고    scopus 로고
    • High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
    • Fu Y, Foden JA, Khayter C et al. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. 9, 822-826 (2013).
    • (2013) Nat. Biotechnol. , vol.9 , pp. 822-826
    • Fu, Y.1    Foden, J.A.2    Khayter, C.3
  • 35
    • 84884165315 scopus 로고    scopus 로고
    • DNA targeting specificity of RNA-guided Cas9 nucleases
    • Hsu PD, Scott DA, Weinstein JA et al. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31, 827-832 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , pp. 827-832
    • Hsu, P.D.1    Scott, D.A.2    Weinstein, J.A.3
  • 36
    • 84884155038 scopus 로고    scopus 로고
    • High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
    • Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol. 31, 839-843 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , pp. 839-843
    • Pattanayak, V.1    Lin, S.2    Guilinger, J.P.3    Ma, E.4    Doudna, J.A.5    Liu, D.R.6
  • 37
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong L, Ran FA, Cox D et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1    Ran, F.A.2    Cox, D.3
  • 38
    • 84861990434 scopus 로고    scopus 로고
    • Precision genome engineering with programmable DNA-nicking enzymes
    • Kim E, Kim S, Kim DH, Choi BS, Choi IY, Kim JS. Precision genome engineering with programmable DNA-nicking enzymes. Genome Res. 22(7), 1327-1333 (2012).
    • (2012) Genome Res. , vol.22 , Issue.7 , pp. 1327-1333
    • Kim, E.1    Kim, S.2    Kim, D.H.3    Choi, B.S.4    Choi, I.Y.5    Kim, J.S.6
  • 39
    • 84861984839 scopus 로고    scopus 로고
    • Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme
    • Wang J, Friedman G, Doyon Y et al. Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme. Genome Res. 22(7), 1316-1326 (2012).
    • (2012) Genome Res. , vol.22 , Issue.7 , pp. 1316-1326
    • Wang, J.1    Friedman, G.2    Doyon, Y.3
  • 40
    • 84861960685 scopus 로고    scopus 로고
    • Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects
    • Ramirez CL, Certo MT, Mussolino C et al. Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects. Nucleic Acids Res. 40(12), 5560-5568 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , Issue.12 , pp. 5560-5568
    • Ramirez, C.L.1    Certo, M.T.2    Mussolino, C.3
  • 41
    • 84876389220 scopus 로고    scopus 로고
    • Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells
    • Holkers M, Maggio I, Liu J et al. Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells. Nucleic Acids Res. 41(5), e63 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , Issue.5 , pp. e63
    • Holkers, M.1    Maggio, I.2    Liu, J.3
  • 42
    • 0029883624 scopus 로고    scopus 로고
    • Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy
    • Black ME, Newcomb TG, Wilson HM, Loeb LA. Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy. Proc. Natl Acad. Sci. USA 93(8), 3525-3529 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , Issue.8 , pp. 3525-3529
    • Black, M.E.1    Newcomb, T.G.2    Wilson, H.M.3    Loeb, L.A.4
  • 43
    • 84862889768 scopus 로고    scopus 로고
    • Suicide gene therapy to increase the safety of chimeric antigen receptor-redirected T lymphocytes
    • Casucci M, Bondanza A. Suicide gene therapy to increase the safety of chimeric antigen receptor-redirected T lymphocytes. J. Cancer 2, 378-382 (2001).
    • (2001) J. Cancer , vol.2 , pp. 378-382
    • Casucci, M.1    Bondanza, A.2
  • 44
    • 33644750264 scopus 로고    scopus 로고
    • Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation
    • Berger C, Flowers ME, Warren EH, Riddell SR. Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation. Blood 107(6), 2294-2302 (2006).
    • (2006) Blood , vol.107 , Issue.6 , pp. 2294-2302
    • Berger, C.1    Flowers, M.E.2    Warren, E.H.3    Riddell, S.R.4
  • 45
    • 34247194881 scopus 로고    scopus 로고
    • Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy
    • Sato T, Neschadim A, Konrad AM, Fowler DH, Lavie A, Medin JA. Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. Mol. Ther. 15(5), 962-970 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.5 , pp. 962-970
    • Sato, T.1    Neschadim, A.2    Konrad, A.M.3    Fowler, D.H.4    Lavie, A.5    Medin, J.A.6
  • 46
    • 84862829497 scopus 로고    scopus 로고
    • Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase
    • Neschadim A, Wang JC, Sato T, Fowler DH, Lavie A, Medin JA. Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase. Mol. Ther. 20(5), 1002-1013 (2012).
    • (2012) Mol. Ther. , vol.20 , Issue.5 , pp. 1002-1013
    • Neschadim, A.1    Wang, J.C.2    Sato, T.3    Fowler, D.H.4    Lavie, A.5    Medin, J.A.6
  • 47
    • 84871978590 scopus 로고    scopus 로고
    • Engineered human Tmpk fused with truncated cell-surface markers: Versatile cell-fate control safety cassettes
    • Scaife M, Pacienza N, Au BC et al. Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes. Gene Ther. 20(1), 24-34 (2013).
    • (2013) Gene Ther. , vol.20 , Issue.1 , pp. 24-34
    • Scaife, M.1    Pacienza, N.2    Au, B.C.3
  • 48
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 392(6673), 245-252 (1998).
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 49
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide or tumor lysate-pulsed dendritic cells
    • Nestle FO, Alijagic S, Gilliet M et al. Vaccination of melanoma patients with peptide or tumor lysate-pulsed dendritic cells. Nat. Med. 4(3), 328-332 (1998).
    • (1998) Nat. Med. , vol.4 , Issue.3 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3
  • 50
    • 84898746976 scopus 로고    scopus 로고
    • Sipuleucel-T and immunotherapy in the treatment of prostate cancer
    • Dawson NA, Roesch EE. Sipuleucel-T and immunotherapy in the treatment of prostate cancer. Expert Opin. Biol. Ther. 14(5), 709-719 (2014).
    • (2014) Expert Opin. Biol. Ther. , vol.14 , Issue.5 , pp. 709-719
    • Dawson, N.A.1    Roesch, E.E.2
  • 51
    • 0842312143 scopus 로고    scopus 로고
    • Lentivirally transduced dendritic cells as a tool for cancer immunotherapy
    • Breckpot K, Dullaers M, Bonehill A et al. Lentivirally transduced dendritic cells as a tool for cancer immunotherapy. J. Gene Med. 5(8), 654-667 (2003).
    • (2003) J. Gene Med. , vol.5 , Issue.8 , pp. 654-667
    • Breckpot, K.1    Dullaers, M.2    Bonehill, A.3
  • 52
    • 4143137360 scopus 로고    scopus 로고
    • Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction
    • Jeon, MS, Atfield, A., Venuprasad, K et al. Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction. Immunity 21(2), 167-177 (2004).
    • (2004) Immunity , vol.21 , Issue.2 , pp. 167-177
    • Jeon, S.M.1    Atfield, A.2    Venuprasad, K.3
  • 53
    • 33745736420 scopus 로고    scopus 로고
    • T-cell tolerance or function is determined by combinatorial costimulatory signals
    • Nurieva, R., Thomas, S., Nguyen, T et al. T-cell tolerance or function is determined by combinatorial costimulatory signals. EMBO J. 25(11), 2623-2633 (2006).
    • (2006) EMBO J. , vol.25 , Issue.11 , pp. 2623-2633
    • Nurieva, R.1    Thomas, S.2    Nguyen, T.3
  • 54
    • 0242579946 scopus 로고    scopus 로고
    • CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine
    • Curtsinger, JM, Johnson, CM, Mescher, MF. CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine. J. Immunol. 171(10), 5165-5171 (2003).
    • (2003) J. Immunol. , vol.171 , Issue.10 , pp. 5165-5171
    • Curtsinger, M.J.1    Johnson, M.C.2    Mescher, F.M.3
  • 55
    • 80053927917 scopus 로고    scopus 로고
    • PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8(+) T cells
    • Karwacz, K, Bricogne, C, MacDonald, D et al. PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8(+) T cells. EMBO Mol. Med. 3(10), 581-592 (2011).
    • (2011) EMBO Mol. Med. , vol.3 , Issue.10 , pp. 581-592
    • Karwacz, K.1    Bricogne, C.2    Macdonald, D.3
  • 56
    • 84908031412 scopus 로고    scopus 로고
    • Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells
    • 2014
    • Pen, JJ, Keersmaecker, BD, Heirman, C et al. (2014). Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells. Gene Ther. 21(3), 262-271 (2014).
    • (2014) Gene Ther. , vol.21 , Issue.3 , pp. 262-271
    • Pen, J.J.1    Keersmaecker, D.B.2    Heirman, C.3
  • 57
    • 70350433514 scopus 로고    scopus 로고
    • Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
    • Fife, BT, Pauken, KE, Eagar, TN et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat. Immunol. 10(11), U1185-U1170 (2009).
    • (2009) Nat. Immunol. , vol.10 , Issue.11 , pp. U1185-U1170
    • Fife, T.B.1    Pauken, E.K.2    Eagar, N.T.3
  • 58
    • 42449157639 scopus 로고    scopus 로고
    • Targeting dendritic cell signaling to regulate the response to immunization
    • Escors, D, Lopes, L, Lin, R et al. Targeting dendritic cell signaling to regulate the response to immunization. Blood 111(6), 3050-3061 (2008).
    • (2008) Blood , vol.111 , Issue.6 , pp. 3050-3061
    • Escors, D.1    Lopes, L.2    Lin, R.3
  • 59
    • 80054088221 scopus 로고    scopus 로고
    • Differential immune responses mediated by adenovirus-and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model
    • Felizardo TC, Wang JCM, Mcgray RA et al. Differential immune responses mediated by adenovirus-and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model. Gene Ther. 18(10), 986-995 (2011).
    • (2011) Gene Ther. , vol.18 , Issue.10 , pp. 986-995
    • Felizardo, T.C.1    Wang, J.C.M.2    McGray, R.A.3
  • 60
    • 33947583453 scopus 로고    scopus 로고
    • In vivo administration of lentiviral vectors triggers a type i interferon response that restricts hepatocyte gene transfer and promotes vector clearance
    • Brown BD, Sitia G, Annoni A et al. In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance. Blood 109(7), 2797-2805 (2007).
    • (2007) Blood , vol.109 , Issue.7 , pp. 2797-2805
    • Brown, B.D.1    Sitia, G.2    Annoni, A.3
  • 61
    • 77951993592 scopus 로고    scopus 로고
    • HIV-1 lentiviral vector immunogenicity is mediated by Toll-Like Receptor 3 (TLR3) and TLR7
    • Breckpot K, Escors D, Arce F et al. HIV-1 lentiviral vector immunogenicity is mediated by Toll-Like Receptor 3 (TLR3) and TLR7. J. Virol. 84(11), 5627-5636 (2010).
    • (2010) J. Virol. , vol.84 , Issue.11 , pp. 5627-5636
    • Breckpot, K.1    Escors, D.2    Arce, F.3
  • 62
    • 0035695838 scopus 로고    scopus 로고
    • Lentiviral vector-mediated tyrosinase-related protein 2 gene transfer to dendritic cells for the therapy of melanoma
    • Metharom P, Ellem KA, Schmidt C, Wei MQ. Lentiviral vector-mediated tyrosinase-related protein 2 gene transfer to dendritic cells for the therapy of melanoma. Hum. Gene Ther. 12(18), 2203-2213 (2001).
    • (2001) Hum. Gene Ther. , vol.12 , Issue.18 , pp. 2203-2213
    • Metharom, P.1    Ellem, K.A.2    Schmidt, C.3    Wei, M.Q.4
  • 63
    • 33846062266 scopus 로고    scopus 로고
    • Gene transfer to dendritic cells induced a protective immunity against melanoma
    • Metharom P, Ellem KA, Wei MQ. Gene transfer to dendritic cells induced a protective immunity against melanoma. Cell Mol. Immunol. 2(4), 281-288 (2005).
    • (2005) Cell Mol. Immunol. , vol.2 , Issue.4 , pp. 281-288
    • Metharom, P.1    Ellem, K.A.2    Wei, M.Q.3
  • 64
    • 34247189774 scopus 로고    scopus 로고
    • Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines
    • Koya RC, Kimura T, Ribas A et al. Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines. Mol. Ther. 15(5), 971-980 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.5 , pp. 971-980
    • Koya, R.C.1    Kimura, T.2    Ribas, A.3
  • 65
    • 33645229133 scopus 로고    scopus 로고
    • An effective cancer vaccine modality: Lentiviral modification of dendritic cells expressing multiple cancer-specific antigens
    • Wang B, He J, Liu C, Chang LJ. An effective cancer vaccine modality: Lentiviral modification of dendritic cells expressing multiple cancer-specific antigens. Vaccine 24(17), 3477-3489 (2006).
    • (2006) Vaccine , vol.24 , Issue.17 , pp. 3477-3489
    • Wang, B.1    He, J.2    Liu, C.3    Chang, L.J.4
  • 66
    • 39849098133 scopus 로고    scopus 로고
    • Tumor protection following vaccination with low doses of lentivirally transduced DCs expressing the self-antigen erbB2
    • Mossoba ME, Walia JS, Rasaiah VI et al. Tumor protection following vaccination with low doses of lentivirally transduced DCs expressing the self-antigen erbB2. Mol. Ther. 16(3), 607-617 (2008).
    • (2008) Mol. Ther. , vol.16 , Issue.3 , pp. 607-617
    • Mossoba, M.E.1    Walia, J.S.2    Rasaiah, V.I.3
  • 67
    • 84876447672 scopus 로고    scopus 로고
    • Dendritic cell directed vaccination with a lentivector encoding PSCA for prostate cancer in mice
    • Xiao L, Joo K-I, Lim M, Wang P. Dendritic cell directed vaccination with a lentivector encoding PSCA for prostate cancer in mice. PLoS ONE 7(11) e48866, (2012).
    • (2012) PLoS ONE , vol.7 , Issue.11 , pp. e48866
    • Xiao, L.1    Joo, K.-I.2    Lim, M.3    Wang, P.4
  • 68
    • 0028285230 scopus 로고
    • Proliferating dendritic cell progenitors in human blood
    • Romani N, Gruner S, Brang D et al. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180(1), 83-93 (1994).
    • (1994) J. Exp. Med. , vol.180 , Issue.1 , pp. 83-93
    • Romani, N.1    Gruner, S.2    Brang, D.3
  • 69
    • 0028289244 scopus 로고
    • Efficient presentation of soluble-antigen by cultured human dendritic cells is maintained by granulocyte-macrophage colony-stimulating factor plus interleukin-4 and down-regulated by Tumor-Necrosis-Factor-alpha
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble-antigen by cultured human dendritic cells is maintained by granulocyte-macrophage colony-stimulating factor plus interleukin-4 and down-regulated by Tumor-Necrosis-Factor-alpha. J. Exp. Med. 179(4), 1109-1118 (1994).
    • (1994) J. Exp. Med. , vol.179 , Issue.4 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 70
    • 0026702360 scopus 로고
    • Interactions of tumor-necrosis-factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell-growth in vitro from early bipotent CD34+ progenitors in human bone-marrow
    • Reid CDL, Stackpoole A, Meager A, Tikerpae J. Interactions of tumor-necrosis-factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell-growth in vitro from early bipotent CD34+ progenitors in human bone-marrow. J. Immunol. 149(8), 2681-2688 (1992).
    • (1992) J. Immunol. , vol.149 , Issue.8 , pp. 2681-2688
    • Reid, C.D.L.1    Stackpoole, A.2    Meager, A.3    Tikerpae, J.4
  • 71
    • 0035404586 scopus 로고    scopus 로고
    • Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells
    • Salmon P, Arrighi JF, Piguet V et al. Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells. J. Gene Med. 3(4), 311-320 (2001).
    • (2001) J. Gene Med. , vol.3 , Issue.4 , pp. 311-320
    • Salmon, P.1    Arrighi, J.F.2    Piguet, V.3
  • 72
    • 0034283912 scopus 로고    scopus 로고
    • Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors
    • Chinnasamy N, Chinnasamy D, Toso JF et al. Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors. Hum. Gene Ther. 11(13), 1901-1909 (2000).
    • (2000) Hum. Gene Ther. , vol.11 , Issue.13 , pp. 1901-1909
    • Chinnasamy, N.1    Chinnasamy, D.2    Toso, J.F.3
  • 73
    • 80052599019 scopus 로고    scopus 로고
    • Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy
    • Senju S, Haruta M, Matsumura K et al. Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy. Gene Ther. 18(9), 874-883 (2011).
    • (2011) Gene Ther. , vol.18 , Issue.9 , pp. 874-883
    • Senju, S.1    Haruta, M.2    Matsumura, K.3
  • 74
    • 3042749373 scopus 로고    scopus 로고
    • Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro
    • Zhan XC, Dravid G, Ye ZH et al. Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet 364(9429), 163-171 (2004).
    • (2004) Lancet , vol.364 , Issue.9429 , pp. 163-171
    • Zhan, X.C.1    Dravid, G.2    Ye, Z.H.3
  • 75
    • 0036721329 scopus 로고    scopus 로고
    • Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
    • Kamath AT, Henri S, Battye F, Tough DF, Shortman K. Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood 100(5), 1734-1741 (2002).
    • (2002) Blood , vol.100 , Issue.5 , pp. 1734-1741
    • Kamath, A.T.1    Henri, S.2    Battye, F.3    Tough, D.F.4    Shortman, K.5
  • 77
    • 33745609027 scopus 로고    scopus 로고
    • Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization
    • He YK, Zhang JY, Donahue C, Falo LD. Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization. Immunity 24(5), 643-656 (2006).
    • (2006) Immunity , vol.24 , Issue.5 , pp. 643-656
    • He, Y.K.1    Zhang, J.Y.2    Donahue, C.3    Falo, L.D.4
  • 78
    • 34548108611 scopus 로고    scopus 로고
    • Successful immunization with a single injection of non-integrating lentiviral vector
    • Negri DRM, Michelini Z, Baroncelli S et al. Successful immunization with a single injection of non-integrating lentiviral vector. Mol. Ther. 15(9), 1716-1723 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.9 , pp. 1716-1723
    • Negri, D.R.M.1    Michelini, Z.2    Baroncelli, S.3
  • 79
    • 73949111672 scopus 로고    scopus 로고
    • HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells
    • Dai B, Yang L, Yang H, Hu B, Baltimore D, Wang P. HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells. Proc. Natl Acad. Sci. USA 106(48), 20382-20387 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.48 , pp. 20382-20387
    • Dai, B.1    Yang, L.2    Yang, H.3    Hu, B.4    Baltimore, D.5    Wang, P.6
  • 80
    • 9344269897 scopus 로고    scopus 로고
    • Expression of costimulatory molecules in human leukemias
    • Hirano N, Takahashi T, Ohtake S et al. Expression of costimulatory molecules in human leukemias. Leukemia 10(7), 1168-1176 (1996).
    • (1996) Leukemia , vol.10 , Issue.7 , pp. 1168-1176
    • Hirano, N.1    Takahashi, T.2    Ohtake, S.3
  • 81
    • 0027239503 scopus 로고
    • Anti-tumor and anti-metastatic activity of interleukin-12 against murine tumors
    • Brunda MJ, Luistro L, Warrier RR et al. Anti-tumor and anti-metastatic activity of interleukin-12 against murine tumors. J. Exp. Med. 178(4), 1223-1230 (1993).
    • (1993) J. Exp. Med. , vol.178 , Issue.4 , pp. 1223-1230
    • Brunda, M.J.1    Luistro, L.2    Warrier, R.R.3
  • 82
    • 0028824039 scopus 로고
    • IL-12 deaths: Explanation and a puzzle
    • Cohen J. IL-12 deaths: explanation and a puzzle. Science 270(5238), 908-908 (1995).
    • (1995) Science , vol.270 , Issue.5238 , pp. 908-908
    • Cohen, J.1
  • 83
    • 0034103809 scopus 로고    scopus 로고
    • Phase i trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: Ability to maintain IFN-gamma induction is associated with clinical response
    • Gollob JA, Mier JW, Veenstra K et al. Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: Ability to maintain IFN-gamma induction is associated with clinical response. Clin. Cancer Res. 6(5), 1678-1692 (2000).
    • (2000) Clin. Cancer Res. , vol.6 , Issue.5 , pp. 1678-1692
    • Gollob, J.A.1    Mier, J.W.2    Veenstra, K.3
  • 84
    • 0033973093 scopus 로고    scopus 로고
    • Cytokines and soluble cytokine receptor induction after IL-12 administration in cancer patients
    • Haicheur N, Escudier B, Dorval T et al. Cytokines and soluble cytokine receptor induction after IL-12 administration in cancer patients. Clin. Exp. Immunol. 119(1), 28-37 (2000).
    • (2000) Clin. Exp. Immunol. , vol.119 , Issue.1 , pp. 28-37
    • Haicheur, N.1    Escudier, B.2    Dorval, T.3
  • 85
    • 0037242365 scopus 로고    scopus 로고
    • Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses
    • Portielje JEA, Lamers CHJ, Kruit WHJ et al. Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses. Clin. Cancer Res. 9(1), 76-83 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , Issue.1 , pp. 76-83
    • Portielje, J.E.A.1    Lamers, C.H.J.2    Kruit, W.H.J.3
  • 86
    • 0031564332 scopus 로고    scopus 로고
    • Enhanced immunogenicity of B cell lymphoma genetically engineered to express both B7-1 and interleukin-12
    • Pizzoferrato E, Chu NR, Hawley TS et al. Enhanced immunogenicity of B cell lymphoma genetically engineered to express both B7-1 and interleukin-12. Hum. Gene Ther. 8(18), 2217-2228 (1997).
    • (1997) Hum. Gene Ther. , vol.8 , Issue.18 , pp. 2217-2228
    • Pizzoferrato, E.1    Chu, N.R.2    Hawley, T.S.3
  • 87
    • 72949086895 scopus 로고    scopus 로고
    • IL-12 immunotherapy of murine leukaemia: Comparison of systemic versus gene modified cell therapy
    • Labbe A, Nelles M, Walia J et al. IL-12 immunotherapy of murine leukaemia: comparison of systemic versus gene modified cell therapy. J. Cell Mol. Med. 13(8B), 1962-1976 (2009).
    • (2009) J. Cell Mol. Med. , vol.13 , Issue.8 B , pp. 1962-1976
    • Labbe, A.1    Nelles, M.2    Walia, J.3
  • 88
    • 84891148986 scopus 로고    scopus 로고
    • Localized interleukin-12 delivery for immunotherapy of solid tumours
    • Wei LZ, Xu Y, Nelles ME et al. Localized interleukin-12 delivery for immunotherapy of solid tumours. J. Cell Mol. Med. 17(11), 1465-1474 (2013).
    • (2013) J. Cell Mol. Med. , vol.17 , Issue.11 , pp. 1465-1474
    • Wei, L.Z.1    Xu, Y.2    Nelles, M.E.3
  • 89
    • 0034663189 scopus 로고    scopus 로고
    • Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage-colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce anti-leukemic immune responses
    • Stripecke R, Cardoso AA, Pepper KA et al. Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage-colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce anti-leukemic immune responses. Blood 96(4), 1317-1326 (2000).
    • (2000) Blood , vol.96 , Issue.4 , pp. 1317-1326
    • Stripecke, R.1    Cardoso, A.A.2    Pepper, K.A.3
  • 90
    • 10944238100 scopus 로고    scopus 로고
    • IL-2/B7. 1 (CD80) fusagene transduction of AML blasts by a self-inactivating lentiviral vector stimulates T cell responses in vitro: A strategy to generate whole cell vaccines for AML
    • Chan L, Hardwick N, Darling D et al. IL-2/B7.1 (CD80) fusagene transduction of AML blasts by a self-inactivating lentiviral vector stimulates T cell responses in vitro: a strategy to generate whole cell vaccines for AML. Mol. Ther. 11(1), 120-131 (2005).
    • (2005) Mol. Ther. , vol.11 , Issue.1 , pp. 120-131
    • Chan, L.1    Hardwick, N.2    Darling, D.3
  • 91
    • 0033120418 scopus 로고    scopus 로고
    • A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission
    • Cortes JE, Kantarjian HM, O'Brien S et al. A pilot study of interleukin-2 for adult patients with acute myelogenous leukemia in first complete remission. Cancer 85(7), 1506-1513 (1999).
    • (1999) Cancer , vol.85 , Issue.7 , pp. 1506-1513
    • Cortes, J.E.1    Kantarjian, H.M.2    O'brien, S.3
  • 92
    • 34247212403 scopus 로고    scopus 로고
    • Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules
    • Suhoski MM, Golovina TN, Aqui NA et al. Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules. Mol. Ther. 15(5), 981-988 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.5 , pp. 981-988
    • Suhoski, M.M.1    Golovina, T.N.2    Aqui, N.A.3
  • 93
    • 0022538117 scopus 로고
    • Transfer of specificity by murine alpha-T-cell and beta-T-cell receptor genes
    • Dembic Z, Haas W, Weiss S et al. Transfer of specificity by murine alpha-T-cell and beta-T-cell receptor genes. Nature 320(6059), 232-238 (1986).
    • (1986) Nature , vol.320 , Issue.6059 , pp. 232-238
    • Dembic, Z.1    Haas, W.2    Weiss, S.3
  • 94
    • 54549106702 scopus 로고    scopus 로고
    • Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition
    • Yang S, Cohen CJ, Peng PD et al. Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition. Gene Ther. 15(21), 1411-1423 (2008).
    • (2008) Gene Ther. , vol.15 , Issue.21 , pp. 1411-1423
    • Yang, S.1    Cohen, C.J.2    Peng, P.D.3
  • 95
    • 84925727210 scopus 로고    scopus 로고
    • Clinicaltrials.gov NCT01795976
    • Clinicaltrials.gov NCT01795976. https://clinicaltrials.gov/ct2/show/NCT01795976
  • 96
    • 84925764677 scopus 로고    scopus 로고
    • Clinicaltrials.gov NCT00910650
    • Clinicaltrials.gov NCT00910650. https://clinicaltrials.gov/ct2/show/NCT00910650
  • 97
    • 77952236875 scopus 로고    scopus 로고
    • Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
    • Bendle GM, Linnemann C, Hooijkaas AI et al. Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat. Med. 16(5), 565-570 (2010).
    • (2010) Nat. Med. , vol.16 , Issue.5 , pp. 565-570
    • Bendle, G.M.1    Linnemann, C.2    Hooijkaas, A.I.3
  • 98
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N. Engl. J. Med. 365(8), 725-733 (2011).
    • (2011) N. Engl. J. Med. , vol.365 , Issue.8 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 99
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • Kochenderfer JN, Dudley ME, Feldman SA et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119(12), 2709-2720 (2012).
    • (2012) Blood , vol.119 , Issue.12 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3
  • 100
    • 0347994955 scopus 로고    scopus 로고
    • Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain
    • Finney HM, Akbar AN, Lawson ADG. Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain. J. Immunol. 172(1), 104-113 (2004).
    • (2004) J. Immunol. , vol.172 , Issue.1 , pp. 104-113
    • Finney, H.M.1    Akbar, A.N.2    Lawson, A.D.G.3
  • 101
    • 3042551216 scopus 로고    scopus 로고
    • Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
    • Imai C, Mihara K, Andreansky M et al. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia 18(4), 676-684 (2004).
    • (2004) Leukemia , vol.18 , Issue.4 , pp. 676-684
    • Imai, C.1    Mihara, K.2    Andreansky, M.3
  • 102
    • 0027471898 scopus 로고
    • Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma-subunit or zeta-subunit of the immunoglobulin and T-cell receptors
    • Eshhar Z, Waks T, Gross G, Schindler DG. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma-subunit or zeta-subunit of the immunoglobulin and T-cell receptors. Proc. Natl Acad. Sci. USA 90(2), 720-724 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , Issue.2 , pp. 720-724
    • Eshhar, Z.1    Waks, T.2    Gross, G.3    Schindler, D.G.4
  • 103
    • 84902582355 scopus 로고    scopus 로고
    • Retargeting NK-92 cells by means of CD19-and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity
    • Boissel L, Betancur-Boissel M, Lu W et al. Retargeting NK-92 cells by means of CD19-and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity. Oncoimmunology 2(10), e26527 (2013).
    • (2013) Oncoimmunology , vol.2 , Issue.10 , pp. e26527
    • Boissel, L.1    Betancur-Boissel, M.2    Lu, W.3
  • 104
    • 84455172814 scopus 로고    scopus 로고
    • Predicting cytokine storms: It's about density
    • Frigault MJ, June CH. Predicting cytokine storms: it's about density. Blood 118(26), 6724-6726 (2011).
    • (2011) Blood , vol.118 , Issue.26 , pp. 6724-6726
    • Frigault, M.J.1    June, C.H.2
  • 105
    • 80455162464 scopus 로고    scopus 로고
    • Inducible apoptosis as a safety switch for adoptive cell therapy
    • Di Stasi A, Tey S-K, Dotti G et al. Inducible apoptosis as a safety switch for adoptive cell therapy. N. Engl. J. Med. 365(18), 1673-1683 (2011).
    • (2011) N. Engl. J. Med. , vol.365 , Issue.18 , pp. 1673-1683
    • Di Stasi, A.1    Tey, S.-K.2    Dotti, G.3
  • 106
    • 83455213653 scopus 로고    scopus 로고
    • Treatment of advanced leukemia in mice with mRNA engineered T cells
    • Barrett DM, Zhao Y, Liu X et al. Treatment of advanced leukemia in mice with mRNA engineered T cells. Hum. Gene Ther. 22(12), 1575-1586 (2011).
    • (2011) Hum. Gene Ther. , vol.22 , Issue.12 , pp. 1575-1586
    • Barrett, D.M.1    Zhao, Y.2    Liu, X.3
  • 107
    • 84890207337 scopus 로고    scopus 로고
    • T cells expressing chimeric antigen receptors can cause anaphylaxis in humans
    • Maus MV, Haas AR, Beatty GL et al. T cells expressing chimeric antigen receptors can cause anaphylaxis in humans. Cancer Immunol. Res. 1(1), 26-31 (2013).
    • (2013) Cancer Immunol. Res. , vol.1 , Issue.1 , pp. 26-31
    • Maus, M.V.1    Haas, A.R.2    Beatty, G.L.3


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